The following is a list of

psychedelic drug Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary states of consciousness (known as psychedelic experiences or "trips").Pollan, Michael (2018). ''How to Change Your Mind: What the New Science o ...

s of various chemical classes, including both naturally occurring and synthetic compounds.

Serotonergic psychedelics Psychedelics are a subclass of Hallucinogen, hallucinogenic drugs whose primary effect is to trigger non-ordinary states of consciousness (known as psychedelic experiences or "trips").Pollan, Michael (2018). ''How to Change Your Mind: What the ...

are usually considered the "classical" psychedelics, whereas the other classes are often seen as having only secondary psychedelic properties; nonetheless all of the compounds listed here are considered psychoactive and hallucinogenic in humans to some degree. Some of these compounds may be classified differently or under more than one category due to a unique structural classification, multiple mechanisms of action, or the fact that the precise

pharmacodynamic Pharmacodynamics (PD) is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs). The effects can include those manifested within animals (including humans), microorganisms, or combinations of organisms (for ...

actions of the compound are not yet completely understood. Because of the vast amount of possible substitutions and chemical analogs of most psychedelic compounds, the total diversity of chemical compounds which produce psychedelic effects in humans is not fully reflected within this list, leaving room for many that have not yet been sufficiently investigated and others that have not yet been discovered. Naturally occurring compounds are marked with a †.

Serotonergic psychedelics ( serotonin 5-HT_2A receptor agonists)

* Indoles ** Tryptamines (more specifically alkylated tryptamines]) *** Psilocin†, also known as '4-HO-DMT'; another active constituent of the '' Psilocybe'' genus of mushrooms; also a metabolite of psilocybin and

psilacetin ''O''-Acetylpsilocin (also known as psilacetin, 4-acetoxy-DMT, 4-AcO-DMT, or synthetic shrooms) is a semi-synthetic psychoactive drug that has been suggested by David E. Nichols, David Nichols to be a potentially useful alternative to psilocybi ...

*** Psilocybin†, also known as '4-PO-DMT'; the primary active constituent of the '' Psilocybe'' genus of mushrooms; its effects are partially attributed to psilocin, to which it is a

prodrug A prodrug is a medication or compound that, after intake, is metabolized (i.e., converted within the body) into a pharmacologically active drug. Instead of administering a drug directly, a corresponding prodrug can be used to improve how the drug ...

via dephosphorylation *** Bufotenin†, also known as '5-HO-DMT' and dimethylserotonin; another constituent of the skin and venom of

psychoactive toads The Colorado River toad (''Incilius alvarius''), formerly known as the Sonoran Desert toad, is found in northern Mexico and the southwestern United States. It exudes toxins from glands within its skin that have psychoactive properties. Descri ...

, its psychedelic activity is disputed; also a metabolite of 5-MeO-DMT *** Baeocystin†, also known as '4-PO-NMT'; another active constituent of the '' Psilocybe'' genus of mushrooms; its psychedelic activity is disputed *** Aeruginascin†, also known as '4-PO-N-TMT', an active constituent of the mushroom '' Inocybe aeruginascens'' ***

5-MeO-DMT 5-MeO-DMT (5-methoxy-''N'',''N''-dimethyltryptamine) or O-methyl-bufotenin is a psychedelic of the tryptamine class. It is found in a wide variety of plant species, and also is secreted by the glands of at least one toad species, the Colorado Ri ...

†, the primary active constituent of the skin and venom of

, a prodrug to bufotenin via demethylation *** ''N,N''-Dimethyltryptamine†, also known as 'DMT'; the primary active constituent of the Amerindian brew ayahuasca; endogenously present in various plants and animals, including humans, possibly a trace amine neurotransmitter ***

5-Bromo-DMT 5-Bromo-DMT (5-bromo-''N'',''N''-dimethyltryptamine) is a psychedelic brominated indole alkaloid found in the sponges ''Smenospongia aurea'' and ''Smenospongia echina'', as well as in ''Verongula rigida'' (0.00142% dry weight) alongside 5,6-Dibr ...

†, was found in the marine invertebrates '' Smenospongia aurea'' and '' Smenospongia echina'', as well as in '' Verongula rigida'' *** ''N''-Methyl-''N''-ethyltryptamine, also known as 'MET' *** ''N''-Methyl-''N''-isopropyltryptamine, also known as 'MiPT' *** N- Methyl-N-propyltryptamine, also known as 'MPT' *** ''N,N''-Diethyltryptamine, also known as 'DET' *** ''N''-Ethyl-''N''-isopropyltryptamine, also known as 'EiPT' *** ''N''-Methyl-''N''-butyltryptamine, also known as 'MBT' *** ''N''-Propyl-''N''-isopropyltryptamine, also known as 'PiPT' *** ''N,N''-Dipropyltryptamine, also known as 'DPT' *** ''N,N''-Diisopropyltryptamine, also known as 'DiPT' *** ''N,N''-Diallyltryptamine, also known as 'DALT' *** ''N,N''-Dibutyltryptamine, also known as 'DBT' *** ''N''-Ethyltryptamine, also known as 'NET' *** ''N''-Methyltryptamine†, also known as 'NMT'; its psychedelic activity is disputed *** Trimethyltryptamine, also known as 'TMT' (

2,N,N-TMT 2,''N,N''-trimethyltryptamine, 2,''N,N''-TMT, or 2-Me-DMT is a tryptamine derivative that is a psychedelic drug. It was invented by Alexander Shulgin and reported in his book TiHKAL (#34). It is claimed to show psychoactive effects at a dosage of ...

5,N,N-TMT 5,''N'',''N''-trimethyltryptamine (5,''N'',''N''-TMT; 5-TMT) is a tryptamine derivative that is a psychedelic drug. It was first made in 1958 by E. H. Young. In animal experiments it was found to be in between DMT and 5-MeO-DMT in potency which ...

, and

7,N,N-TMT 7,''N'',''N''-trimethyltryptamine (7-methyl-DMT, 7-TMT), is a tryptamine derivative which acts as an agonist of 5-HT2 receptors. In animal tests, both 7-TMT and its 5-methoxy derivative 5-MeO-7-TMT produced behavioural responses similar to th ...

) *** α-Methyltryptamine, also known as 'αMT' and 'AMT'; also has entactogenic properties *** α-Ethyltryptamine, also known as 'αET' and 'AET'; also has entactogenic properties *** α,''N''-DMT ***

α,N,N-Trimethyltryptamine α,''N'',''N''-Trimethyltryptamine (α,''N'',''N''-TMT, α-TMT, ATMT) is a psychoactive drug of the tryptamine chemical class which acts as a psychedelic hallucinogen. It is similar in structure to the other psychedelics of the tryptamine class ...

, also known as 'α-TMT' ***

Ethocybin Ethocybin (CEY-19; 4-phosphoryloxy-DET; 4-PO-DET) is a homologue of the mushroom alkaloid psilocybin, and a semi-synthetic psychedelic alkaloid of the tryptamine family. Effects of ethocybin are comparable to those of a shorter LSD or psilocybi ...

, also known as '4-PO-DET', 'CEY-19', and 'CEY-39' ***

4-HO-MET 4-HO-MET (4-hydroxy-''N''-methyl-''N''-ethyltryptamine, metocin, or methylcybin), is a lesser-known psychedelic drug. It is a structural− and functional analog of psilocin as well as the 4-hydroxyl analog of methylethyltryptamine (MET). 4-HO-M ...

, also known as 'Metocin', 'Methylcybin', and 'Colour' *** 4-HO-DET, also known as 'Ethocin' and 'CZ-74' ***

4-HO-MPT 4-Hydroxy-''N''-methyl-''N''-propyltryptamine, commonly known as 4-HO-MPT or meprocin, is a psychedelic drug in the tryptamine class of chemical compounds and is a higher homologue of the naturally occurring substituted tryptamine psilocin as wel ...

, also known as 'Meprocin' ***

4-HO-MiPT 4-HO-MiPT (miprocin, 4-hydroxy-''N''-methyl-''N''-isopropyltryptamine) is a synthetic substituted aromatic compound and a lesser-known psychedelic tryptamine. It is thought to be a serotonergic psychedelic, similar to magic mushrooms, LSD and ...

, also known as 'Miprocin' ***

4-HO-MALT 4-HO-MALT (4-hydroxy-''N''-methyl-''N''-allyltryptamine) is a tryptamine derivative which has been sold as a designer drug, first being detected in Slovenia in 2021. See also * 4-HO-MiPT * 4-HO-McPT * 4-HO-MPT * 4-AcO-DALT * 5-MeO-MALT 5-Me ...

***

4-HO-DPT 4-HO-DPT (4-hydroxy-''N'',''N''-dipropyltryptamine, Deprocin) is a substituted tryptamine with psychedelic effects. It is the 4-hydroxyl analog of dipropyltryptamine (DPT). In 2019, Chadeayne et al. solved the crystal structure of the fumarate sa ...

, also known as 'Deprocin' ***

4-HO-DiPT 4-Hydroxy-N,N-diisopropyltryptamine (4-HO-DiPT or Iprocin) is a synthetic psychedelic drug. It is a higher homologue of psilocin, 4-HO-DET, and is a positional isomer of 4-HO-DPT and has a tryptamine molecular sub-structure. Dosage 4-HO-DiPT i ...

, also known as 'Iprocin' *** 4-HO-DALT, also known as 'Daltocin' ***

4-HO-DBT 4-Hydroxy-''N,N''-dibutyltryptamine (4-HO-DBT) is a psychedelic drug belonging to the tryptamine family. It is found either as its crystalline hydrochloride salt or as an oily or crystalline base. 4-HO-DBT was first made by the chemist Alexa ...

***

4-HO-DSBT 4-HO-DsBT (4-hydroxy-''N,N''-di-''sec''-butyltryptamine) is a tryptamine derivative which acts as a serotonin receptor agonist. It was first made by Alexander Shulgin and is mentioned in his book TiHKAL, but was never tested by him. However it h ...

*** 4-HO-αMT ***

4-HO-MPMI 4-HO-MPMI (also known as 4-Hydroxy-''N''-methyl-(α,''N''-trimethylene)-tryptamine or lucigenol) is a tryptamine derivative that is a psychedelic drug. It was developed by the team led by David Nichols from Purdue University in the late 1990s. ...

, also known as 'Lucigenol' *** 4-HO-TMT *** 4-HO-1,N,N-TMT, also known as '1-Me-4-HO-DMT' and '1-methylpsilocin' *** 4-HO-5-MeO-DMT, also known as 'Psilomethoxin' ***

4-AcO-DMT ''O''-Acetylpsilocin (also known as psilacetin, 4-acetoxy-DMT, 4-AcO-DMT, or synthetic shrooms) is a semi-synthetic psychoactive drug that has been suggested by David Nichols to be a potentially useful alternative to psilocybin for pharmacolog ...

, also known as 'psiloacetin'; its effects are partially attributed to psilocin, to which it is a prodrug via

deacetylation : In organic chemistry, acetylation is an organic esterification reaction with acetic acid. It introduces an acetyl group into a chemical compound. Such compounds are termed ''acetate esters'' or simply ''acetates''. Deacetylation is the opposit ...

*** 4-AcO-MET, also known as 'Metacetin' *** 4-AcO-MiPT *** 4-AcO-MALT *** 4-AcO-DET, also known as 'Ethacetin' *** 4-AcO-EiPT, also known as 'Ethipracetin' ***

4-AcO-DPT 4-Acetyloxy-''N,N''-dipropyltryptamine (or 4-AcO-DPT) is a tryptamine derivative. 4-AcO-DPT has been sold as a designer drug. It is an ester of 4-HO-DPT, a psychedelic tryptamine first synthesized by Alexander Shulgin. Anecdotal reports indicate t ...

, also known as 'Depracetin' *** 4-AcO-DiPT, also known as 'Ipracetin' ***

4-AcO-DALT 4-Acetyloxy-''N,N''-diallyltryptamine (or 4-AcO-DALT) is a tryptamine derivative. It has been sold as a designer drug, but little other information is available. It was first officially identified in seized drug samples in 2012. See also * DALT ...

, also known as 'Daltacetin' ***

4-MeO-DMT 4-MeO-DMT (4-methoxy-''N'',''N''-dimethyltryptamine) is a tryptamine derivative which has some central activity in animal tests similar to that of related psychedelic tryptamine drugs, although with significantly lower potency than either 5-MeO ...

***

4-MeO-MiPT 4-MeO-MiPT, or 4-methoxy-''N''-methyl-''N''-isopropyltryptamine, is a lesser-known Psychedelics, dissociatives and deliriants, psychedelic drug. It is the 4-methoxy analog (chemistry), analog of MiPT. 4-MeO-MiPT was first synthesized by Alexander ...

***

5-MeO-NMT 5-MeO-NMT (5-methoxy-''N''-methyltryptamine) is an organic chemical compound, being the 5-methoxy analog (chemistry), analog of N-Methyltryptamine, ''N''-methyltryptamine (NMT). It was first isolated from ''Phalaris arundinacea'' (reed canary gras ...

† ***

5-MeO-MET 5-MeO-MET (5-Methoxy-N-methyl-N-ethyltryptamine) is a relatively rare designer drug from the substituted tryptamine family, related to compounds such as N-methyl-N-ethyltryptamine and 5-MeO-DMT. It was first synthesised in the 1960s and was stud ...

*** 5-MeO-MPT ***

5-MeO-MiPT 5-MeO-MiPT is a psychedelic and hallucinogenic drug, used by some as an entheogen. It has structural and pharmacodynamic properties similar to the drugs 5-MeO-DiPT, DiPT, and MiPT. It is commonly used as a "substitute" for 5-MeO-DiPT because o ...

, also known as 'Moxy'; also has entactogenic properties ***

5-MeO-MALT 5-MeO-MALT (5-methoxy-''N''-methyl-''N''-allyltryptamine) is a lesser-known psychedelic drug that is closely related to 5-MeO-DALT and has been sold online as a designer drug. Legality 5-MeO-MALT is illegal in Hungary. Sweden's public health a ...

***

5-MeO-DET 5-MeO-DET or 5-methoxy-''N,N''-diethyltryptamine is a hallucinogenic tryptamine. Pharmacology 5-MeO-DET inhibits serotonin reuptake with an IC50 value of 2.4 μM and activates 5-HT2A receptors with an EC50 value of 8.11 nM. Effects Low dosages ...

***

5-MeO-EiPT 5-MeO EiPT is a psychedelic of the tryptamine class that has been sold online as a designer drug. Legality 5-MeO-EiPT is illegal in Japan. 5-MeO-EiPT is illegal in Italy. Sweden's public health agency suggested classifying 5-MeO-EiPT as a hazar ...

*** 5-MeO-EPT ***

5-MeO-PiPT 5-Methoxy-''N''-propyl-''N''-isopropyltryptamine (5-MeO-PiPT) is a substituted tryptamine derivative which is claimed to have psychedelic effects. It has been sold as a designer drug, first being identified in 2021 in British Columbia, Canada. ...

*** 5-MeO-DPT ***

5-MeO-DiPT 5-Methoxy-''N'',''N''-diisopropyltryptamine (5-MeO-DiPT, sometimes called Foxy Methoxy or simply Foxy) is a psychedelic tryptamine and the methoxy derivative of diisopropyltryptamine (DiPT). Pharmacology The mechanism that produces the purport ...

, also known as 'Foxy Methoxy' ***

5-MeO-DALT 5-MeO-DALT or ''N,N''- di allyl-5-methoxy tryptamine is a psychedelic tryptamine first synthesized by Alexander Shulgin. Chemistry The full name of the chemical is ''N''-allyl-''N''-indol-3-yl)ethyl group">ethyl] propene, prop-2-en-1- amine. It i ...

*** 5-MeO-AMT, 5-MeO-αMT, also has entactogenic properties ***

5-MeO-αET 5-Methoxy-alpha-ethyltryptamine (5-MeO-α-ET) is a psychoactive drug and member of the tryptamine chemical class. It produces psychedelic and stimulant effects. Dosage 5-MeO-α-ET, when used recreationally, is usually taken orally at dosages ...

, also has entactogenic properties ***

5-MeO-MPMI 5-MeO-MPMI (also known as 5-Methoxy-''N''-methyl-(α,''N''-trimethylene)tryptamine) is a tryptamine derivative that is a psychedelic drug. It was first developed by the team led by JE Macor in 1992, and subsequently investigated by the team led b ...

*** 5-MeO-2,N,N-TMT , also known as 'Indomethacin' and 'Indapex' *** 5-MeO-7,N,N-TMT *** 5-MeO-a,N-DMT, also known as 'α,N,O-TMS' *** 4-F-5-MeO-DMT *** 5-MeS-DMT *** 5-Me-MiPT, its psychedelic activity is disputed ***

5-HO-DiPT 5-HO-DiPT (5-hydroxy-''N,N''-di-''iso''-propyltryptamine) is a tryptamine derivative which acts as a serotonin receptor agonist. It is primarily known as a metabolite of the better known psychoactive drug 5-MeO-DiPT, but 5-HO-DiPT has also rarely ...

*** 2-α-DMT *** 2-Me-DET *** 4-Me-αMT *** 4-Me-αET, also has entactogenic properties *** 7-Me-αET, also has entactogenic properties *** 4,5-DHP-AMT, also known as 'AL-37350A' ***

4,5-DHP-DMT 1-(2-Dimethylaminoethyl)dihydropyrano(3,2-e)indole (4,5-DHP-DMT) is a tricyclic tryptamine derivative which acts as a potent and reasonably selective partial agonist for the serotonin receptor 5-HT, with a Ki of 17.0 nM, and moderate selectivit ...

***

4,5-MDO-DMT 4,5-MDO-DMT, or 4,5-methylenedioxy-''N'',''N''-dimethyltryptamine, is a lesser-known psychedelic drug. It is the 4,5-methylenedioxy analog of DMT. 4,5-MDO-DMT was first synthesized by Alexander Shulgin, though in his book ''TiHKAL'' it was not te ...

***

4,5-MDO-DiPT 4,5-MDO-DiPT, or 4,5-methylenedioxy-N,N-diisopropyltryptamine, is a lesser-known psychedelic drug. It is the 4,5- methylenedioxy analog of DiPT. 4,5-MDO-DiPT was first synthesized by Alexander Shulgin. In his book ''TiHKAL'' (''Tryptamines I Hav ...

***

5,6-MDO-DiPT 5,6-MDO-DiPT, or 5,6-methylenedioxy-''N'',''N''-diisopropyltryptamine, is a lesser-known psychedelic drug. It is the 5,6-methylenedioxy analog of DiPT. 5,6-MDO-DiPT was first synthesized by Alexander Shulgin. It is mentioned in his book ''TiHKAL ...

*** 5,6-MDO-MiPT *** 5-Fluoro-αMT, also has entactogenic properties ***

6-Fluoro-αMT 6-Fluoro-α-methyltryptamine (6-fluoro-AMT, 6F-AMT) is a tryptamine derivative related to compounds such as alpha-methyltryptamine and 5-MeO-AMT, which has been sold as a designer drug. Animal tests showed it to be somewhat less active than A ...

*** 6-Fluoro-DMT *** ''N,N''-Tetramethylenetryptamine, also known as 'Pyr-T' ***

4-HO-pyr-T 4-HO-pyr-T (4-hydroxy-''N'',''N''-tetramethylenetryptamine) is a lesser-known psychedelic drug. It is the 4-hydroxyl analog of pyr-T. 4-HO-pyr-T was first synthesized by Alexander Shulgin. In his book ''TiHKAL ''TIHKAL: The Continuation ...

***

5-MeO-pyr-T 5-MeO-pyr-T (5-methoxy-''N'',''N''-tetramethylenetryptamine) is a lesser-known psychedelic drug. It is the 5- methoxy analog of pyr-T. 5-MeO-pyr-T was first synthesized by Hunt & Brimblecombe, who credited S. Mitzal for characterization of che ...

***

RU-28306 RU-28306 is a tricyclic tryptamine derivative which acts as a serotonin receptor agonist, with selectivity for 5-HT1 and 5-HT2 subtypes. It can be regarded either as a conformationally constrained derivative of DMT, or a structurally simplifi ...

, also known as '4,a-Methylene-N,N-DMT' ***

O-4310 O-4310 (1-isopropyl-6-fluoro-psilocin) is a tryptamine derivative developed by Organix Inc which acts as a serotonin receptor agonist. It is claimed to have an EC50 of 5nM at 5-HT2A with 89% efficacy vs 5-HT, and 100x selectivity over 5-HT2C, ...

, also known as '6-Fluoro-1-Isopropyl-4-HO-DMT' *** CP-132,484, also known as '4,5-DHP-1-Methyltryptamine' ** Benzofuran derivatives (technically not tryptamines) *** Dimemebfe, also known as '5-MeO-BFE' ***

5-MeO-DiBF 5-MeO-DiBF is a psychedelic that has been sold online as a designer drug and was first definitively identified in December 2015 by a forensic laboratory in Slovenia. It is thought to act as an agonist for the 5-HT1A and 5-HT2 family of serot ...

** Ibogoids (can be classified as complex tryptamines) *** Ibogaine†, the primary active constituent of

iboga ''Tabernanthe iboga'' (iboga) is an evergreen rainforest shrub native to Central Africa. A member of the Apocynaceae family indigenous to Gabon, the Democratic Republic of Congo, and the Republic of Congo, it is cultivated across Central Africa ...

rootbark; also has dissociative properties *** Voacangine†, another active constituent of

rootbark ** Ergolines (more specifically lysergamides, which can be classified as complex tryptamines; also contain a phenethylamine backbone) *** Lysergic acid diethylamide, also known as 'LSD' and 'acid' *** Lysergic acid amide†, also known as 'LSA' and 'ergine'; the primary active constituent of morning glory and Hawaiian baby woodrose seeds *** ''N1''-Methyl-lysergic acid diethylamide, also known as 'MLD-41' *** ''N''-Acetyl-lysergic acid diethylamide, also known as 'ALD-52' *** 1-Propionyl-lysergic acid diethylamide, also known as '1P-LSD'; its effects are partially attributed to LSD, to which it is a prodrug via hydrolyzation *** 1‐cyclopropanoyl‐''d''‐lysergic acid diethylamide, also known as '1cP-LSD' *** 1-valeryl-D-lysergic acid diethylamide, also known as '1V-LSD' *** 6-Allyl-6-''nor''-lysergic acid diethylamide, also known as 'AL-LAD' *** 6-Butyl-6-''nor''-lysergic acid diethylamide, also known as 'BU-LAD' *** 6-Ethyl-6-''nor''-lysergic acid diethylamide, also known as 'ETH-LAD' *** 1-Propionyl-6-Ethyl-6-''nor''-lysergic acid diethylamide, also known as '1P-ETH-LAD' *** 6-Propyl-6-''nor''-lysergic acid diethylamide, also known as 'PRO-LAD' *** 6-Cyclopropyl-6-''nor''-lysergic acid diethylamide, also known as 'CYP-LAD' *** 6-''nor''-Lysergic acid diethylamide, also known as 'PARGY-LAD' *** Lysergic acid ethylamide, also known as 'LAE-32' *** Lysergic acid α-hydroxyethylamide†, also known as 'LSH' and 'LAH'; another active constituent of morning glory seeds; an active constituent of some species of fungi *** Lysergic acid 2-butyl amide, also known as 'LSB' ***

Lysergic acid 3-pentyl amide Lysergic acid 3-pentyl amide (3-Pentyllysergamide, LSP) is an analogue of LSD originally researched by David E. Nichols and colleagues at Purdue University. It has similar binding affinity to LSD itself as both a 5-HT1A and 5-HT2A agonist, and ...

, also known as 'LSP' *** Lysergic acid methyl ester, also known as 'LSME' *** Lysergic acid 2,4-dimethylazetidide, also known as 'LSZ' and 'LA-SS-Az' *** Lysergic acid piperidine, also known as 'LSD-Pip'; its psychedelic activity is disputed *** ''N,N''-Dimethyl-lysergamide, also known as 'DAM-57' ***

Methylisopropyllysergamide Methylisopropyllysergamide (lysergic acid methylisopropyl amide, MIPLA) is an analogue of LSD that was originally discovered by Albert Hofmann at Sandoz during the original structure-activity research into LSD. It has subsequently been investigat ...

, also known as 'MIPLA' *** ''N,N''-Diallyllysergamide, also known as 'DAL' *** ''N''-Pyrrolidyllysergamide, also known as 'LPD-824' *** ''N''-Morpholinyllysergamide, also known as 'LSM-775' *** 1-methyl-lysergic acid butanolamide, also known as 'Methysergide'; the active constituent of Sansert and Deseril; a prodrug which has to be metabolized to methylergometrine to become psychoactive *** Lysergic acid β-propanolamide†, also known as 'Ergonovine' and 'Ergometrine'; another active constituent of morning glory seeds, and an active constituent of

ergot Ergot ( ) or ergot fungi refers to a group of fungi of the genus ''Claviceps''. The most prominent member of this group is ''Claviceps purpurea'' ("rye ergot fungus"). This fungus grows on rye and related plants, and produces alkaloids that ca ...

fungi *** Lysergic acid 1-butanolamide†, also known as 'Methylergonovine', 'Methergine', and 'Methylergometrine'; another active constituent of morning glory seeds and of

fungi *

Phenethylamine Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine, which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission by binding to trace amin ...

s (more specifically alkoxylated phenethylamines) ** Substituted phenethylamines ***

Mescaline Mescaline or mescalin (3,4,5-trimethoxyphenethylamine) is a naturally occurring psychedelic protoalkaloid of the substituted phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin. Biological sou ...

†, the primary active constituent of certain cacti, such as

peyote The peyote (; ''Lophophora williamsii'' ) is a small, spineless cactus which contains psychoactive alkaloids, particularly mescaline. ''Peyote'' is a Spanish word derived from the Nahuatl (), meaning "caterpillar cocoon", from a root , "to gl ...

and San Pedro *** Lophophine†, also known as 'MMDPEA'; another active constituent of certain cacti, such as

and San Pedro; also has entactogenic properties ***

Isomescaline Isomescaline (2,3,4-trimethoxyphenethylamine) is a lesser-known compound based on a well-known psychedelic drug. It is an isomer of mescaline, as well as an analog of TIM-2, TIM-3, and TIM-4. Isomescaline was first synthesized by Alexander Sh ...

*** Cyclopropylmescaline *** Thioisomescaline (2-TIM, 3-TIM, and 4-TIM) *** 4-Desoxymescaline *** Jimscaline *** Escaline *** Metaescaline *** Thiometaescaline (3-TME, 4-TME, and 5-TME) ***

Trisescaline Trisescaline (3,4,5-triethoxyphenethylamine) is a lesser-known phenethylamine prepared as a possible psychedelic drug. It is an analog of mescaline. Trisescaline was first synthesized by Alexander Shulgin. In his book '' PiHKAL'', both the minimu ...

*** Thiotrisescaline (3-T-TRIS and 4-T-TRIS) ***

Symbescaline Symbescaline, or 3,5-di ethoxy-4-methoxyphenethylamine, is a lesser-known psychedelic drug. It is an isomer of asymbescaline. Symbescaline was first synthesized by Alexander Shulgin. In his book '' PiHKAL (Phenethylamines i Have Known And Loved)' ...

***

Asymbescaline Asymbescaline (3,4-diethoxy-5-methoxyphenethylamine) is a lesser-known psychedelic drug. It is a homolog of mescaline. Asymbescaline was first synthesized by Alexander Shulgin. In his book '' PiHKAL'', the dosage range is listed as 200–280&nbs ...

*** Thiosymbescaline (3-TSB and 4-TSB) *** Phenescaline *** Allylescaline, also known as 'AL' *** Methallylescaline *** Proscaline *** Isoproscaline *** Metaproscaline ***

Thioproscaline Thioproscaline, or 3,5-dimethoxy-4-propyl thio phenethylamine, is a lesser-known psychedelic drug. It is the 4-propyl thio analog of mescaline. Thioproscaline was first synthesized by Alexander Shulgin. In his book '' PiHKAL (Phenethylamines i ...

*** Buscaline *** Thiobuscaline *** α-ethylmescaline, also known as 'AEM' *** Ariadne, also known as 'α-Et-DOM', '4C-D', and 'Dimoxamine' ***

Macromerine Macromerine is a phenethylamine derivative. It was first identified from the cactus '' Coryphantha macromeris''. It can also be found in ''C. runyonii'', ''C. elephantidens'', and other related members of the family Cactaceae. The plants may hav ...

*** MEPEA ***

TOM Tom or TOM may refer to: * Tom (given name), a diminutive of Thomas or Tomás or an independent Aramaic given name (and a list of people with the name) Characters * Tom Anderson, a character in ''Beavis and Butt-Head'' * Tom Beck, a character ...

(2-TOM and 5-TOM) *** Bis-TOM *** TOMSO, also known as '2-methoxy-4-methyl-5-methylsulfinylamphetamine' *** TOET (2-TOET and 5-TOET) *** BOH *** BOM, also known as 'β-Methoxy-mescaline' *** β-D *** 4-D *** DME *** F-2 *** F-22 *** FLEA, also known as 'MDHMA' ***

MDPH 3,4-Methylenedioxyphentermine (MDPH) is a lesser-known psychedelic drug. MDPH was first synthesized by Alexander Shulgin. In his book '' PiHKAL (Phenethylamines i Have Known And Loved)'', the dosage range is listed as 160–240 mg, and the ...

*** MDMP *** Propynyl ***

2C family 2C (2C-''x'') is a general name for the family of psychedelic phenethylamines containing methoxy groups on the 2 and 5 positions of a benzene ring. Most of these compounds also carry lipophilic substituents at the 4 position, usually resulting in ...

(2,5-dimethoxy, 4-substituted phenethylamines) ****

βk-2C-B βk-2C-B (Bk-2C-B; 2-Amino-1-(4-bromo-2,5-dimethoxyphenyl)ethan1-one) is a novel psychedelic substance. It is the beta (β) ketone structural analogue of 2C-B, a psychedelic drug of the 2C (psychedelics), 2C family. It is used as a recreational ...

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2C-B 2C-B (4-Bromo-2,5-dimethoxyphenethylamine) is a psychedelic drug of the 2C family. It was first synthesized by Alexander Shulgin in 1974. In Shulgin's book '' PiHKAL'', the dosage range is listed as 12–24 mg. As a recreational drug, 2C-B is so ...

**** 2CB-2EtO **** 2CB-5EtO **** 2CB-diEtO ****

2C-B-FLY 2C-B-FLY is a psychedelic phenethylamine and designer drug of the 2C family. It was first synthesized in 1996 by Aaron P. Monte. Chemistry 2C-B-FLY is 8-bromo-2,3,6,7-benzo-dihydro-difuran-ethylamine. The full name of the chemical is 2-(8-brom ...

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2C-B-BUTTERFLY 2C-B-BUTTERFLY (2C-B-MOTH-BIKHIR, 2C-B-BFLY) is a conformationally-restricted derivative of the phenethylamine hallucinogen 2C-B, which was discovered in 1999 by Michael S. Whiteside and Aaron Monte. It is a ring-expanded homologue of the bett ...

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2C-C 2C-C is a Psychedelics, dissociatives and deliriants, psychedelic drug of the 2C (psychedelics), 2C family. It was first synthesized by Alexander Shulgin, sometimes used as an entheogen. In his book ''PiHKAL, PiHKAL (Phenethylamines i Have Known A ...

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2C-D 2C-D (2,5-dimethoxy-4-methylphenethylamine or 2C-M) is a psychedelic drug of the 2C family that is sometimes used as an entheogen. It was first synthesized in 1970 by a team from the Texas Research Institute of Mental Sciences, and its activity w ...

**** 2CD-2EtO **** 2CD-diEtO **** 2CD-5EtO ****

2C-E 2C-E is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin and documented in his book '' PiHKAL''. Like the other substances in its family, it produces sensory and cognitive effects in its physical reacti ...

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2C-EF 2C-EF is a lesser-known psychedelic drug. It was originally named by Alexander Shulgin as described in his book PiHKAL (Phenethylamines i Have Known And Loved), but he never synthesised it himself, though it has been synthesised and its activity ...

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2C-F 2C-F (4-fluoro-2,5-dimethoxyphenethylamine) is a lesser-known psychedelic drug of the 2C family. It was first synthesized by Alexander Shulgin. In his book '' PiHKAL'', the minimum dosage is listed as 250 mg. 2C-F may be found as a browni ...

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2C-G 2C-G is a psychedelic phenethylamine of the 2C family. First synthesized by Alexander Shulgin, it is sometimes used as an entheogen. It has structural and pharmacodynamic properties similar to 2C-D and Ganesha. Like many of the phenethylami ...

(2C-G-1, 2C-G-2, 2C-G-3, 2C-G-4, 2C-G-5, 2C-G-6, and 2C-G-N) ****

2C-H 2C-H (2,5-dimethoxyphenethylamine) is a lesser-known substituted phenethylamine of the 2C family. History 2C-H was first synthesized in 1932 by Johannes S. Buck. Use 2C-H is used as a precursor in the synthesis of other substituted phenethyl ...

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2C-I 2C-I is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin and described in his 1991 book '' PiHKAL'' (''Phenethylamines I Have Known and Loved''). The drug has been used recreationally as psychedelic and ...

**** 2CI-2EtO ****

2C-iP 2C-iP (also known as Jelena) is a relatively potent and long acting psychedelic phenethylamine and compound from the 2C family that was first synthesized by Dmitri Ger and has been sold online as a designer drug. It is a structural analog of ...

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2C-N 2C-N (2,5-dimethoxy-4-nitrophenethylamine) is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin. Chemistry The full name of the chemical is 2-(2,5-dimethoxy-4-nitrophenyl)ethanamine. Salts of 2C-N have ...

**** 2C-O **** 2C-O-4 ****

2C-P 2C-P is a relatively potent and long acting psychedelic phenethylamine of the 2C family. Chemistry 2C-P is 2,5-dimethoxy-4-''n''-propylphenethylamine. The full name of the chemical is 2-(2,5-dimethoxy-4-propylphenyl)ethanamine. The hydrochlori ...

**** 2C-SE ****

2C-T 2C-T (or 4-methylthio-2,5-DMPEA) is a psychedelic and hallucinogenic drug of the 2C family. It is used by some as an entheogen. It has structural and pharmacodynamic properties similar to the drugs mescaline and 2C-T-2. It was first synthesize ...

**** 2CT-5EtO ****

2C-T-2 2C-T-2 is a psychedelic and entactogenic phenethylamine of the 2C family. It was first synthesized in 1981 by Alexander Shulgin, and rated by him as one of the "magical half-dozen" most important psychedelic phenethylamine compounds. The drug ...

**** 2CT-2-2EtO **** 2CT-2-5EtO **** 2CT-2-diEtO ****

2C-T-4 2C-T-4 (2,5-dimethoxy-4-isopropylthiophenethylamine) is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin and is used as entheogenic recreational drug. Chemistry 2C-T-4 is the 2-carbon homolog of ale ...

(2C-T-4 and Ψ-2C-T-4) **** 2CT-4-2EtO ****

2C-T-7 2C-T-7 is a psychedelic phenethylamine of the 2C family. In his book '' PiHKAL: A Chemical Love Story'', Alexander Shulgin lists the dosage range as 10 to 30 mg. 2C-T-7 is generally taken orally, and produces psychedelic and entactogenic effec ...

**** 2CT-7-2EtO ****

2C-T-8 2C-T-8 is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin, sometimes used as an entheogen. Chemistry The full name of the chemical is 2,5-dimethoxy-4-cyclopropylmethyl thiophenethylamine. The compou ...

**** 2C-T-9 **** 2C-T-13 ****

2C-T-15 2C-T-15 or 2,5-dimethoxy-4-(β-cyclopropylthio)phenethylamine is a psychedelic phenethylamine of the 2C family. It was presumably first synthesized by Alexander Shulgin and reported in his book '' PiHKAL (Phenethylamines i Have Known And Loved)' ...

****

2C-T-16 2C-T-16 is a lesser-known psychedelic drug. It was originally named by Alexander Shulgin as described in his book PiHKAL (Phenethylamines i Have Known And Loved), however while Shulgin began synthesis of this compound he only got as far as the n ...

**** 2C-T-17 ****

2C-T-19 2C-T-19 (2,5-dimethoxy-4-butylthiophenethylamine) is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin. Dosage In his book '' PiHKAL'', Shulgin describes synthesis of the final intermediate of 2C-T-1 ...

, ****

2C-T-21 2C-T-21 (4-(2-fluoroethylthio)-2,5-dimethoxyphenethylamine) is a psychedelic phenethylamine of the 2C family sometimes used as an entheogen. It was first synthesized by Alexander Shulgin. Dosage In his book '' PiHKAL (Phenethylamines i Have K ...

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2C-TFM 2C-TFM is a psychedelic phenethylamine of the 2C family. It was first synthesized in the laboratory of David E. Nichols. It has also been called 2C-CF3, a name derived from the Para-trifluoromethyl group it contains. Chemistry 2C-TFM is a code ...

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2C-YN 2C-YN is an analog of phenethylamine that can be synthesized from 2C-I. Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-YN, although Daniel Trachsel lists it as having a dosage of around 50mg and a d ...

**** BOB, also known as 'β-Methoxy-2C-B' **** BOD, also known as 'β-Methoxy-2C-D' ****

BOHD BOHD (4-methyl-2,5-dimethoxy-beta-hydroxyphenethylamine) is a lesser-known psychedelic drug. It is the beta- hydroxy derivative of 2C-D. BOHD was first synthesized by Alexander Shulgin. In his book '' PiHKAL'', the minimum dosage is listed as 50& ...

, also known as 'β-Hydroxy-2C-D' **** HOT-2 **** HOT-7 **** HOT-17 **** Indane derivatives (technically not phenethylamines) *****

2CB-Ind 2CB-Ind is a conformationally-restricted derivative of the phenethylamine hallucinogen 2C-B, discovered in 1974 by Alexander Shulgin. It acts as a moderately potent and selective agonist for the 5-HT2A and 5-HT2C receptors, but unlike the cor ...

**** Benzocyclobutene derivatives (technically not phenethylamines) ***** 2C-BCB, also known as 'TCB-2' **** NBOMe derivatives ***** NBOMe-mescaline ***** 2C-H-NBOMe, also known as '25H-NBOMe' *****

2C-C-NBOMe 25C-NBOMe (NBOMe-2C-C, 2C-C-NBOMe, Cimbi-82) is a psychedelic drug and derivative of the psychedelic phenethylamine 2C-C. 25C-NBOMe appeared on online vendor sites in 2010 but was not reported in the literature until 2011. It acts as a potent ag ...

, also known as '25C-NBOMe' ***** 2CBCB-NBOMe, also known as 'NBOMe-TCB-2' ***** 2CBFly-NBOMe, also known as 'Cimbi-31' ***** 2C-B-NBOMe, also known as '25B-NBOMe', 'M25B-NBOMe', 'BOM 2-CB', 'Cimbi-36', 'Nova', or 'New Nexus' ***** 2C-I-NBOMe, also known as '25I-NBOMe', 'Cimbi-5', "Solaris", or "N-Bomb" ***** 2C-TFM-NBOMe, also known as '25TFM-NBOMe' ***** 2C-D-NBOMe, also known as '25D-NBOMe' *****

2C-G-NBOMe 25G-NBOMe (NBOMe-2C-G) is a derivative of the phenethylamine hallucinogen 2C-G, which acts as a highly potent partial agonist for the human 5-HT2A receptor. Legality Sweden The Riksdag added 25G-NBOMe to Narcotic Drugs Punishments Act und ...

, also known as '25G-NBOMe' ***** 2C-E-NBOMe, also known as '25E-NBOMe' ***** 2C-P-NBOMe, also known as '25P-NBOMe' ***** 2C-iP-NBOMe, also known as '25iP-NBOMe' ***** 2C-CN-NBOMe, also known as '25CN-NBOMe' ***** 2C-N-NBOMe, also known as '25N-NBOMe' ***** 2C-T-NBOMe, also known as '25T2-NBOMe' ***** 2C-T-4-NBOMe, also known as '25T4-NBOMe' ***** 2C-T-7-NBOMe, also known as '25T7-NBOMe' ***** DMBMPP, 2-Benzylpiperidine analogue of 25B-NBOMe **** NBOH derivatives ***** 2C-C-NBOH, also known as '25C-NBOH' and 'NBOH-2CC' ***** 2C-B-NBOH, also known as '25B-NBOH' ***** 2C-I-NBOH, also known as '25I-NBOH' ***** 2C-CN-NBOH, also known as '25CN-NBOH' and 'NBOH-2C-CN' **** NBMD derivatives ***** 2C-I-NBMD, also known as '25I-NBMD' **** NBF derivatives ***** 2C-C-NBF, also known as '25C-NBF' ***** 2C-B-NBF, also known as '25B-NBF' ***** 2C-I-NBF, also known as '25I-NBF' ** Substituted

amphetamine Amphetamine (contracted from alpha- methylphenethylamine) is a strong central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity. It is also commonly used ...

s (''a''lpha-''m''ethyl-''ph''en''et''hyl''amines'') *** 3C family (3,5-dimethoxy, 4-substituted amphetamines) ****

3C-E 3C-E is a psychedelic of the amphetamine class. It was first synthesized by Alexander Shulgin. In his book '' PiHKAL'', Shulgin lists the dosage range as 30 to 60 mg, consumed orally. The duration of action was stated to be 8–12 hours. T ...

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3C-P 3C-P (α-Methyl-4-propoxy-3,5-dimethoxyphenethylamine) is a psychedelic phenethylamine. It has structural and pharmacodynamic properties similar to the drugs mescaline, proscaline, and amphetamine. Little information exists on the human pharmaco ...

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3C-DFE 3C-DFE is a lesser-known psychedelic drug, which is a fluorinated derivative of 3C-E. It was first synthesised by Daniel Trachsel in 2002, and has been reported as showing similar psychedelic activity to related compounds, with a dose range of ar ...

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3C-BZ 3C-BZ (4-benzyloxy-3,5-dimethoxyamphetamine) is a lesser-known psychedelic drug and a substituted amphetamine. 3C-BZ was first synthesized by Alexander Shulgin. In his book '' PiHKAL'', the dosage range is listed as 25–200 mg and the durat ...

***

DOx 4-Substituted-2,5-dimethoxyamphetamines (DO''x'') is a chemical class of substituted amphetamine derivatives featuring methoxy groups at the 2- and 5- positions of the phenyl ring, and a substituent such as alkyl or halogen at the 4- po ...

family (2,5-dimethoxy, 4-substituted amphetamines) **** DOAM **** DOB ****

Meta-DOB Meta-DOB, or 5- bromo-2,4-dimethoxy amphetamine, is a lesser-known psychedelic drug. It is similar in structure to DOB. Meta-DOB was first synthesized by Alexander Shulgin. In his book '' PiHKAL (Phenethylamines i Have Known And Loved)'', the ...

**** Methyl-DOB **** DOBU **** DOC **** DOEF **** DOET, also known as 'DOE' **** DOI ****

DOM Dom or DOM may refer to: People and fictional characters * Dom (given name), including fictional characters * Dom (surname) * Dom La Nena (born 1989), stage name of Brazilian-born cellist, singer and songwriter Dominique Pinto * Dom people, an et ...

, also known as 'STP' **** Ψ-DOM **** DON **** DOPR **** DOiPR **** DOT, also known as 'Aleph' (Aleph-2, Aleph-4, Aleph-6, and Aleph-7) **** Meta-DOT **** Ortho-DOT **** DOTFM *** Phenylcyclopropylamine derivatives (technically not amphetamines) **** DMCPA *** DMMDA *** DMMDA-2 *** 2,5-dimethoxy-3,4-dimethylamphetamine, also known as 'Ganesha'; (G-3, G-4, G-5, and G-N) *** 4-methyl-2,5-dimethoxymethamphetamine, also known as 'Beatrice', 'MDO-D', and 'MDOM' *** 2,N-dimethyl-4,5-methylenedioxyamphetamine, also known as 'Madam-6' *** Dimethoxyamphetamine (2,4-DMA, 2,5-DMA, and 3,4-DMA) *** Trimethoxyamphetamine (TMA-2, TMA-6) *** Tetramethoxyamphetamine *** Br-DragonFLY *** TFMFly *** 2-Bromo-4,5-methylenedioxyamphetamine *** 4-Bromo-3,5-dimethoxyamphetamine *** EEE *** EEM *** EME *** EMM *** EDMA *** EIDA ***

Ethyl-J Ethylbenzodioxolylbutanamine (EBDB; Ethyl-J) is a lesser-known entactogen, stimulant, and psychedelic. It is the ''N''-ethyl analogue of benzodioxylbutanamine (BDB; "J"), and also the α-ethyl analogue of methylenedioxyethylamphetamine (MDEA ...

, also known as 'EBDB' *** Methyl-J, also known as 'MDMB' ***

Ethyl-K ''N''-Ethyl-1,3-benzodioxolylpentanamine (EBDP; Ethyl-K; 3,4-methylenedioxy-''N''-ethyl-α-propylphenethylamine) is a psychoactive drug and member of the phenethylamine chemical class which acts as an entactogen, psychedelic, and stimulant. ...

, also known as 'EBDP' ***

Methyl-K ''N''-Methyl-1,3-benzodioxolylpentanamine (MBDP; Methyl-K, UWA-091), also known as 3,4-methylenedioxy-α-propyl-''N''-methylphenethylamine, is a psychoactive drug of the phenethylamine chemical class. It is the ''N''-methyl analogue of 1,3- be ...

, also known as 'MBDP' and 'UWA-91' *** IDNNA *** Iris *** MDAI ***

MDMAI 5,6-Methylenedioxy-''N''-methyl-2-aminoindane (MDMAI), is a drug developed in the 1990s by a team led by David E. Nichols at Purdue University. It acts as a non-neurotoxic and highly selective serotonin releasing agent (SSRA) in animals and a ...

*** MDAT *** MDMAT ***

MDAL Methylenedioxyallylamphetamine (MDAL or 3,4-methylenedioxy-''N''-allylamphetamine) is a lesser-known psychedelic drug. It is also the ''N''-allyl derivative of 3,4-methylenedioxyamphetamine (MDA). MDAL was first synthesized by Alexander Shulgin ...

*** MDBU ***

MDBZ Methylenedioxybenzylamphetamine, abbreviated MDBZ, and systematically named 3,4-methylenedioxy-''N''-benzylamphetamine, is a psychedelic drug. It is the ''N''-benzyl derivative of 3,4-methylenedioxyamphetamine (MDA). MDBZ was first synthesized by ...

***

MDDM 3,4-Methylenedioxy-''N'',''N''-dimethylamphetamine (MDDM) is a lesser-known research chemical. It is also the ''N'',''N''-dimethyl analog of 3,4-methylenedioxyamphetamine (MDA). MDDM was first synthesized by Alexander Shulgin. In his book '' PiHK ...

*** MDIP *** MDMEOET ***

MDMEO 3,4-Methylenedioxy-''N''-methoxyamphetamine (MDMEO, MDMEOA, or MDMeOA) is a lesser-known psychedelic drug and a substituted amphetamine. It is also the N-methoxy analogue of MDA. MDMEO was first synthesized by Alexander Shulgin. In his book '' ...

*** MDOH, also known as 'MDH' *** MDHOET *** MDPL *** MDCPM ***

MDPR 3,4-Methylenedioxy-''N''-propylamphetamine (MDPR, "Phantom") is a lesser-known psychedelic drug and a substituted amphetamine. MDPR was first synthesized by Alexander Shulgin. In his book '' PiHKAL'', the minimum dosage is listed as 200 ...

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MEDA Meda may refer to: Places * Meda de Mouros, a parish in Tábua Municipality, Portugal * Medas, a parish in Gondomar Municipality, Portugal * Meda-Ela, Sri Lanka * Međa (Leskovac), village in the municipality of Leskovac, Serbia * Meda, Lombard ...

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MEM Mem (also spelled Meem, Meme, or Mim) is the thirteenth letter of the Semitic abjads, including Hebrew mēm , Aramaic Mem , Syriac mīm ܡ, Arabic mīm and Phoenician mēm . Its sound value is . The Phoenician letter gave rise to the Greek mu ...

*** Methyl-DMA *** MMDA, also known as '3-methoxy-MDA' (2T-MMDA-3a and 4T-MMDA-2) ***

MMDA-2 MMDA-2 (2-methoxy-4,5-methylenedioxyamphetamine) is a psychedelic drug of the amphetamine class. It is closely related to MMDA and MDA. Alexander Shulgin was likely the first to synthesize MMDA-2. In his book '' PiHKAL'', the dose is listed as ...

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5-Methyl-MDA 5-Methyl-3,4-methylenedioxyamphetamine (5-Methyl-MDA) is an entactogen and psychedelic designer drug of the amphetamine class. It is a ring-methylated homologue of MDA and a structural isomer of MDMA. Effects and research Drug discriminatio ...

*** MEE *** MME *** MPM ***

DiFMDA Difluoromethylenedioxyamphetamine (DiFMDA) is a substituted derivative of 3,4-methylenedioxyamphetamine 3,4-Methylenedioxyamphetamine (also known as MDA and sass) is an empathogen-entactogen, psychostimulant, and psychedelic drug of the am ...

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5-APB 5-APB (abbreviation of "5-(2-aminopropyl)benzofuran"; see infobox for the correct IUPAC name) is an empathogenic psychoactive compound of the substituted benzofuran, substituted amphetamine and substituted phenethylamine classes. 5-APB and oth ...

*** 6-APB, also known as 'Benzofury' ***

5-APDB 5-(2-Aminopropyl)-2,3-dihydrobenzofuran (5-APDB, 3-Desoxy-MDA, EMA-4) is a putative entactogen drug of the phenethylamine and amphetamine classes. It is an analogue of MDA where the heterocyclic 3-position oxygen from the 3,4-methylenedioxy rin ...

*** 6-APDB ***

5-MAPB 5-MAPB (1-(benzofuran-5-yl)-''N''-methylpropan-2-amine) is an entactogenic designer drug similar to MDMA in its structure and effects. Legal Status Canada 5-MAPB is not listed itself in the CDSA but since it is structurally related to MDMA it ...

***

5-MAPDB 5-MAPDB (1-(2,3-dihydrobenzofuran-5-yl)-N-methylpropan-2-amine) is a chemical compound which acts as an entactogenic drug. It is structurally related to drugs like 5-APDB and 5-MAPB, which have similar effects to MDMA and have been used as recr ...

*** 6-MAPDB, its psychedelic activity is disputed *** 6-MAPB *** 6-EAPB ***

5-EAPB 5-EAPB (1-(benzofuran-5-yl)-''N''-ethylpropan-2-amine) is a potentially entactogenic amphetamine Amphetamine (contracted from alpha- methylphenethylamine) is a strong central nervous system (CNS) stimulant that is used in the treatment ...

*** Para-Methoxyamphetamine, also known as 'PMA' and '4-MA' *** Paramethoxymethamphetamine, also known as 'PMMA', 'Methyl-MA', and '4-MMA' ***

4-Ethylamphetamine 4-Ethylamphetamine (4-EA) is a substituted amphetamine derivative which has been sold as a designer drug. It is mainly known as a synthetic intermediate used as a building block to manufacture larger molecules, but 4-EA is closely related in che ...

, also known as '4-EA' ***

3-Methoxy-4-methylamphetamine 3-Methoxy-4-methylamphetamine (MMA) is an entactogen and psychedelic drug of the phenethylamine and amphetamine classes. It was first synthesized in 1970 and was encountered as a street drug in Italy in the same decade.de Zorzi C, Cavalli A, Un ...

, also known as 'MMA' ***

4-Methylmethamphetamine 4-Methylmethamphetamine (4-MMA) or Mephedrine, is a putative stimulant and entactogen drug of the amphetamine class. It is the β-de keto analogue of mephedrone. See also * 4-Methylamphetamine (4-MA) * 4-Methylmethcathinone (4-MMC) * 3-Met ...

, also known as '4-MMA' ***

4-Methylthioamphetamine 4-Methylthioamphetamine (4-MTA) is a designer drug of the substituted amphetamine class developed in the 1990s by a team led by David E. Nichols, an American pharmacologist and medical chemist, at Purdue University. It acts as a non-neurotoxic hi ...

, also known as '4-MTA' ***

4-Fluoroamphetamine 4-Fluoroamphetamine (4-FA; 4-FMP; PAL-303; "Flux"), also known as ''para''-fluoroamphetamine (PFA) is a psychoactive research chemical of the phenethylamine and substituted amphetamine chemical classes. It produces stimulant and entactogenic ef ...

, also known as '4-FA', 'PAL-303', 'Flux', 'Flits', 'R2D2', and 'Miley' *** Norfenfluramine, also known as '3-TFMA' ***

Para-Iodoamphetamine ''para''-Iodoamphetamine (PIA), also known as 4-iodoamphetamine (4-IA), is a research chemical of the phenethylamine and amphetamine chemical classes. It acts as a selective serotonin releasing agent and is also a MAOI Monoamine oxidas ...

, also known as 'PIA', '4-iodoamphetamine', and '4-IA' *** Para-Chloroamphetamine, also known as 'PCA', '4-chloroamphetamine', and '4-CA' * Benzoxazines (more specifically cyclopropylethynylated benzoxazines) ** Substituted benzoxazines ***

Efavirenz Efavirenz (EFV), sold under the brand names Sustiva among others, is an antiretroviral medication used to treat and prevent HIV/AIDS. It is generally recommended for use with other antiretrovirals. It may be used for prevention after a needlest ...

, the active constituent of Sustiva, Stocrin, and Efavir

Empathogens/entactogens ( serotonin (5-HT) releasing agents)

* Substituted methylenedioxy-phenethylamines (

MDxx Substituted methylenedioxy- phenethylamines (MDxx) are a large chemical class of derivatives of the phenethylamines, which includes many psychoactive drugs that act as entactogens, psychedelics, and/or stimulants, as well as entheogens. These a ...

) ** MDMA, also known as 'Molly', and 'Mandy' ** MDA, also known as 'Sass' **

2,3-MDA 2,3-Methylenedioxyamphetamine (2,3-MDA) or ORTHO-MDA is an amphetamine derivative which is mentioned in PIHKAL as a fairly potent and long-lasting stimulant drug, but with little or none of the entactogenic effects associated with its better-k ...

, also known as 'ORTHO-MDA' **

** MMDA, also known as '3-methoxy-MDA' ** MDEA, also known as 'MDE' ** MBDB **

** MDBU **

** MDIP ** MDMEOET **

** MDOH, also known as 'MDH' ** MDHOET ** MDPL ** MDCPM **

** BDB, also known as 'MDB' and 'J' **

** EIDA **

, also known as 'EBDP' ** Lophophine†, also known as 'MMDPEA'; an active constituent of certain cacti, such as

and San Pedro * Substituted amphetamines (exclusively; most of the substituted methylenedioxy-phenethylamines also overlap this category) ** EDMA ** Para-Methoxyamphetamine, also known as 'PMA' ** Paramethoxymethamphetamine, also known as 'PMMA' and 'Methyl-MA' **

, also known as '4-EA' **

, also known as 'MMA' **

, also known as '4-MMA' **

, also known as '4-MTA' **

, also known as '4-FA', 'PAL-303', 'Flux', 'Flits', 'R2D2', and 'Miley' ** Norfenfluramine, also known as '3-TFMA' **

, also known as 'PIA', '4-iodoamphetamine', and '4-IA' ** Para-Chloroamphetamine, also known as 'PCA', '4-chloroamphetamine', and '4-CA' * Substituted cathinones ** Methylone, also known as 'bk-MDMA' and 'MDMC' **

Ethylone Ethylone, also known as 3,4-methylenedioxy-''N''-ethylcathinone (MDEC, βk-MDEA), is a recreational designer drug classified as an entactogen, stimulant, and psychedelic of the phenethylamine, amphetamine, and cathinone chemical classes. It is t ...

, also known as 'bk-MDEA' and 'MDEC' **

Eutylone Eutylone (also known as β-keto-1,3-benzodioxolyl-''N''-ethylbutanamine, bk-EBDB, and ''N''-ethylbutylone) is a stimulant and empathogenic compound developed in the 1960s, which is classified as a designer drug. It was first reported to the EMCD ...

, also known as 'bk-EBDB' ** Butylone, also known as 'bk-MBDB' **

Pentylone Pentylone (β-Keto-Methylbenzodioxolylpentanamine, βk-Methyl-K, βk-MBDP, methylenedioxypentedrone, or 1‐(3,4‐methylenedioxyphenyl)‐2‐(methylamino)pentan‐1‐one) is a stimulant developed in the 1960s. It is a substituted cathinone ( ...

, also known as 'bk-Methyl-K' and 'bk-MBDP' **

4-Ethylmethcathinone 4-Ethylmethcathinone (4-EMC) is a recreational designer drug of the stimulant and entactogen class. It is a structural isomer of 4-MEC and 3,4-DMMC. It has been identified in many countries around the world, initially in Europe but was first fo ...

, also known as '4-EMC' **

3-Methylmethcathinone 3-Methylmethcathinone, also known as 3-MMC and metaphedrone, is a designer drug from the substituted cathinone family. 3-MMC is closely related in structure to the more commonly known illicit drug mephedrone (4-MMC), and is also illegal in most ...

, also known as '3-MMC' * Substituted benzofurans **

** 6-APB **

** 6-APDB **

** 6-MAPDB, its psychedelic activity is disputed ** 6-MAPB **

** 6-EAPB ** 5-MBPB * Substituted tetralins ** MDAT ** MDMAT ** 6-CAT ** Tetralinylaminopropane, also known as 'TAP' and '6-APT' * Substituted indanes ** Trifluoromethylaminoindane, also known as 'TAI' **

Ethyltrifluoromethylaminoindane ''N''-Ethyl-5-trifluoromethyl-2-aminoindane (ETAI) is a psychoactive drug and research chemical with putative entactogenic effects. It functions as a selective serotonin releasing agent (SSRA). ETAI is the aminoindane analogue of fenfluramine ...

, also known as 'ETAI' ** 5-Iodo-2-aminoindane, also known as '5-IAI' **

MMAI 5-Methoxy-6-methyl-2-aminoindane (MMAI) is a drug developed in the 1990s by a team led by David E. Nichols at Purdue University. It acts as a non-neurotoxic and highly selective serotonin releasing agent (SSRA) and produces entactogen effects in ...

** MDAI **

Indanylaminopropane 5-(2-Aminopropyl)-2,3-dihydro-1''H''-indene (5-APDI), also known as indanylaminopropane (IAP), IAP (psychedelic), 2-API(2-aminopropylindane), indanametamine, and, incorrectly, as indanylamphetamine, is an entactogen and psychedelic drug of the a ...

, also known as '5-APDI' and 'IAP' * Substituted naphthalenes ** Naphthylaminopropane, also known as 'NAP' and 'PAL-287' * Substituted phenylisobutylamines (alpha-ethyl-phenethylamines) **

4-chlorophenylisobutylamine 4-Chlorophenylisobutylamine (4-CAB, AEPCA), also known as 4-chloro-α-ethylphenethylamine, is an entactogen and stimulant drug of the phenethylamine class. It is an analogue of ''para''-chloroamphetamine (PCA) where the alpha position methyl ...

, also known as '4-chloro-α-ethylphenethylamine', '4-CAB', and 'AEPCA' **

4-Methylphenylisobutylamine 4-Methylphenylisobutylamine (4-MAB), also known as 4-methyl-α-ethylphenethylamine, is a stimulant drug of the phenethylamine class. See also * Phenylisobutylamine * 4-Methylamphetamine * Benzodioxolylbutanamine 1,3-Benzodioxolylbutanamine ...

, also known as '4-MAB' ** Ariadne, also known as 'α-Et-DOM', '4C-D', and 'Dimoxamine' * Alpha-substituted (-alkylated) tryptamines ** α-methyltryptamine, also known as 'αMT' and 'AMT' ** 5-MeO-AMT, 5-MeO-αMT ** α-ethyltryptamine, also known as 'αET' and 'AET' ** 4-Me-αET ** 7-Me-αET **

Cannabinoids ( CB-1 cannabinoid receptor ligands)

* Phytocannabinoids ** Δ⁹-THC†,

agonist An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an antagonist blocks the action of the ago ...

; the primary active constituent of cannabis *** 11-hydroxy-Δ⁹-THC, agonist; an active metabolite of

orally administered Oral administration is a route of administration where a substance is taken through the mouth. Per os abbreviated to P.O. is sometimes used as a direction for medication to be taken orally. Many medications are taken orally because they are i ...

Δ⁹-THC; not technically a phytocannabinoid ** CBD†, negative allosteric modulator, another major active constituent of cannabis **

CBN CBN, or cbn, may refer to: Broadcasting organizations * Radio stations in St. John's, Newfoundland: ** CBN (AM), CBC Radio One ** CBN-FM, CBC Music * Chronicle Broadcasting Network, the predecessor of ABS-CBN * CBN (Australian TV station), a TV s ...

†, a minor active constituent of cannabis, also a metabolite of THC and a product of its degradation **

THCV Tetrahydrocannabivarin (THCV, THV, O-4394, GWP42004) is a homologue of tetrahydrocannabinol (THC) having a propyl (3-carbon) side chain instead of a pentyl (5-carbon) group on the molecule, which makes it produce very different effects from THC. ...

†, a minor active constituent of cannabis *

Synthetic cannabinoids Synthetic cannabinoids are a class of designer drug molecules that bind to the same receptors to which cannabinoids (THC, CBD and many others) in cannabis plants attach. These novel psychoactive substances should not be confused with synthetic ...

(C6)-CP 47,497 (C6)-CP 47,497 (CP 47,497 dimethylhexyl homologue) is a synthetic cannabinoid, a CP 47,497 homologue. Its systematic name is 2- 1''S'',3''R'')-3-hydroxycyclohexyl5-(1,1-dimethylhexyl)phenol. See also * Synthetic cannabis Synthetic cannabin ...

(C9)-CP 47,497 (C9)-CP 47,497 (CP 47,497 dimethylnonyl homologue) is a synthetic cannabinoid, a CP 47,497 homologue. Its systematic name is 2- 1''S'',3''R'')-3-hydroxycyclohexyl5-(1,1-dimethylnonyl)phenol. See also * Synthetic cannabis * (C6)-CP 47,497 ( ...

** 1-Butyl-3-(2-methoxybenzoyl)indole ** 1-Butyl-3-(4-methoxybenzoyl)indole ** 1-Pentyl-3-(2-methoxybenzoyl)indole ** 2-Isopropyl-5-methyl-1-
(2,6-dihydroxy-4-nonylphenyl)cyclohex-1-ene **

4-HTMPIPO 4-HTMPIPO is a synthetic cannabinoid drug first identified in smoking products purchased from online vendors in 2012. 4-HTMPIPO is the product resulting from the electrophilic addition of water to the cyclopropane moiety of synthetic cannabinoi ...

4-Nonylphenylboronic acid 4-Nonylphenylboronic acid is a potent and selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH), with an IC50 of 9.1nM, and 870x selectivity for FAAH over the related enzyme MAGL, which it inhibits with an IC50 of 7900nM. It is al ...

** 5Br-UR-144 ** 5Cl-APINACA ** 5Cl-UR-144 ** 5F-3-pyridinoylindole **

5F-AB-FUPPYCA 5F-AB-FUPPYCA (also known as AZ-037) is a pyrazole-based synthetic cannabinoid that is presumed to be an agonist of the CB1 receptor and has been sold online as a designer drug. It was first detected by the EMCDDA as part of a seizure of 540& ...

5F-ADB-PINACA 5F-ADB-PINACA is a cannabinoid designer drug that is an ingredient in some synthetic cannabis products. It is a potent agonist of the CB1 receptor and CB2 receptor with EC50 values of 0.24 nM and 2.1 nM respectively. Metabolism Tw ...

5F-ADBICA 5F-ADBICA (also known as 5F-ADB-PICA) is an indole-based synthetic cannabinoid that is a potent agonist at CB1 receptors and CB2 receptors with EC50 values of 0.77 nM and 1.2 nM respectively. Legal Status China As of October 2015 5F-ADBICA ...

5F-ADB 5F-ADB (also known as 5F-MDMB-PINACA) is an indazole-based synthetic cannabinoid from the indazole-3-carboxamide family, which has been used as an active ingredient in synthetic cannabis products and has been sold online as a designer drug. 5F-A ...

5F-AMB 5F-AMB (also known as 5F-MMB-PINACA and 5F-AMB-PINACA) is an indazole-based synthetic cannabinoid from the indazole-3-carboxamide family, which has been used as an active ingredient in synthetic cannabis products. It was first identified in Japa ...

5F-APINACA 5F-APINACA (also known as 5F-AKB-48 or 5F-AKB48) is an indazole-based synthetic cannabinoid that has been sold online as a designer drug. Structurally it closely resembles cannabinoid compounds from patent WO 2003/035005 but with a 5-fluoropenty ...

5F-CUMYL-PINACA 5F-CUMYL-PINACA (also known as SGT-25 and sometimes sold in e-cigarette form as C-Liquid) is an indazole-3-carboxamide based synthetic cannabinoid. 5F-CUMYL-PINACA acts as a potent agonist for the cannabinoid receptors, with the original patent c ...

** 5F-EMB-PINACA **

5F-NNE1 5F-NNE1 (also known as 5F-NNEI and 5F-MN-24) is an indole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a designer drug. Given the known metabolic liberation (and presence as ...

5F-PB-22 5F-PB-22 (5F-QUPIC or quinolin-8-yl 1-pentyfluoro-1''H''-indole-3-8-carboxylate) is a designer drug which acts as a cannabinoid agonist. The structure of 5F-PB-22 appears to have been designed with an understanding of structure–activity relati ...

5F-PCN 5F-PCN (also known as 5F-MN-21) is an azaindole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a designer drug. It is closely related to NNE1. Given the known metabolic liberat ...

** 5F-PY-PICA ** 5F-PY-PINACA ** 5F-SDB-006 ** HHC ** A-796,260 **

A-834,735 A-834,735 is a drug developed by Abbott Laboratories that acts as a potent cannabinoid receptor full agonist at both the CB1 and CB2 receptors, with a ''K''i of 12 nM at CB1 and 0.21 nM at CB2. Replacing the aromatic 3-benzoyl or 3-n ...

** A-836,339 ** A-955,840 ** A-40174 ** A-41988 **

A-42574 A4 most often refers to: *A4 paper, a paper size defined by the ISO 216 standard, measuring 210 × 297 mm A4 and variants may also refer to: Science and mathematics * British NVC community A4 (''Hydrocharis morsus-ranae - Stratiotes aloide ...

AB-001 AB-001 (1-pentyl-3-(1-adamantoyl)indole) is a designer drug that was found as an ingredient in synthetic cannabis smoking blends in Ireland in 2010 and Hungary and Germany in 2011. It is unclear who AB-001 was originally developed by, but it is s ...

** AB-CHFUPYCA ** AB-CHMFUPPYCA ** AB-CHMINACA **

AB-FUBICA AB-FUBICA is a drug that acts as a potent agonist for the cannabinoid receptors, with EC50 values of 21 nM at CB1 and 15 nM at CB2. See also * AB-FUBINACA * ADB-FUBICA ADB-FUBICA is a drug that acts as a potent agonist for the cannabinoi ...

** AB-FUBINACA 2-fluorobenzyl isomer ** AB-FUBINACA ** AB-PICA ** AB-PINACA ** Abnormal cannabidiol ** ADAMANTYL-THPINACA ** ADB-CHMINACA **

ADB-FUBICA ADB-FUBICA is a drug that acts as a potent agonist for the cannabinoid receptors, with EC50 values of 2.6 nM at CB1 and 3.0 nM at CB2. See also * AB-FUBICA * AB-FUBINACA AB-FUBINACA is a drug that acts as a potent agonist for the cannabin ...

ADB-FUBINACA ADB-FUBINACA is a designer drug identified in synthetic cannabis blends in Japan in 2013. In 2018, it was the third-most common synthetic cannabinoid identified in drugs seized by the Drug Enforcement Administration. The (''S'')-enantiomer of A ...

** ADB-PINACA ** ADBICA ** ADSB-FUB-187 ** Ajulemic acid **

AM-087 AM-087 (part of the AM cannabinoid series) is an analgesic drug which acts as a cannabinoid agonist. It is a derivative of Δ8-THC, substituted on the 3-position side chain. AM-087 is a potent CB1 agonist with a Ki of 0.43 nM, making it ...

AM-411 AM-411 (part of the AM cannabinoid series) is an analgesic drug that is a cannabinoid agonist. It is a derivative of Δ8-THC substituted with an adamantyl group at the 3-position, demonstrating that the binding pocket for the alkyl chain at this ...

** AM-630 ** AM-630 ** AM-679 ** AM-694 **

AM-855 AM-855 (part of the AM cannabinoid series) is an analgesic drug which is a cannabinoid agonist. It is a derivative of Δ8Tetrahydrocannabinol with a conformationally restricted side chain which has been bound into a fourth ring fused to the aro ...

** AM-883 **

AM-905 AM-905 (part of the AM cannabinoid series) is an analgesic drug which is a cannabinoid agonist. It is conformationally restricted by virtue of the double bond on its side chain, leading an increased affinity for and selectivity between CB1 an ...

** AM-906 ** AM-919 ** AM-926 ** AM-938 **

AM-1220 AM-1220 is a drug that acts as a potent and moderately selective agonist for the cannabinoid receptor CB1, with around 19 times selectivity for CB1 over the related CB2 receptor. It was originally invented in the early 1990s by a team led by Th ...

** AM-1221 ** AM-1235 ** AM-1241 **

AM-1248 AM-1248 is a drug that acts as a moderately potent agonist for both the cannabinoid receptors CB1 and CB2, but with some dispute between sources over its exact potency and selectivity. Replacing the 3-(1-naphthoyl) group found in many indole de ...

** AM-1346 ** AM-1387 ** AM-1714 ** AM-2201 **

AM-2232 AM-2232 (1-(4-cyanobutyl)-3-(naphthalen-1-oyl)indole) is a drug that acts as a potent but unselective agonist for the cannabinoid receptors, with a ''K''i of 0.28 nM at CB1 and 1.48 nM at CB2. In the United States, all CB1 receptor ...

** AM-2233 ** AM-2389 ** AM-4030 ** AM-4113 ** AM-6527 ** AM-6545 ** AM-251 ** AM-281 **

AM-404 AM404, also known as ''N''-arachidonoylaminophenol, is an active metabolite of paracetamol (acetaminophen), responsible for all or part of its analgesic action and anticonvulsant effects. Chemically, it is the amide formed from 4-aminophenol a ...

AMB-CHMINACA AMB-CHMINACA or MMB-CHMINACA (also known as MA-CHMINACA) is an indazole-based synthetic cannabinoid that is a potent agonist of the CB1 receptor and has been sold online as a designer drug. Legal status AMB-CHMINACA is listed in the Fifth Sche ...

** AMB-FUBINACA **

AMG-1 AMG-1 (part of the AM cannabinoid series) is an analgesic drug which is a cannabinoid agonist. It is a derivative of Δ8-THC with a rigidified and extended 3-position side chain. AMG-1 is a potent agonist at both CB1 and CB2 with moderate sel ...

** AMG-3 ** AMG-36 ** AMG-41 ** APICA ** APINACA, also known as 'AKB48' ** APP-FUBINACA ** Arachidonoyl serotonin **

ACEA Acea is a surname. Notable people with the surname include: * Eusebio Acea (born 1969), Cuban rower * Francis Acea (born 1967), Cuban artist *John Adriano Acea (1917–1963), American jazz pianist *Raidel Acea Raidel Acea Morales (born 21 Octo ...

** ACPA ** Arvanil ** AZ-11713908 ** BAY 38-7271 **

BAY 59-3074 BAY 59-3074 is a drug which is a cannabinoid receptor partial agonist developed by Bayer AG. It has analgesic An analgesic drug, also called simply an analgesic (American English), analgaesic (British English), pain reliever, or painkiller ...

** BIM-018 **

Biochanin A Biochanin A is an ''O''-methylated isoflavone. It is a natural organic compound in the class of phytochemicals known as flavonoids. Biochanin A can be found in red clover in soy, in alfalfa sprouts, in peanuts, in chickpea (''Cicer arietinum'' ...

BML-190 BML-190 (Indomethacin morpholinylamide) is a drug used in scientific research that acts as a selective CB2 inverse agonist. BML-190 is structurally derived from the NSAID indomethacin but has a quite different biological activity. The activity p ...

** Nabidrox (Canbisol) **

Cannabicyclohexanol Cannabicyclohexanol (CCH, CP 47,497 dimethyloctyl homologue, (C8)-CP 47,497) is a cannabinoid receptor agonist drug, developed by Pfizer in 1979. On 19 January 2009, the University of Freiburg in Germany announced that an analog of CP 47,497 was ...

** Cannabipiperidiethanone ** CAY-10401 ** CAY-10429 ** CAY-10508 **

CB-13 CB-13 (CRA13, SAB-378) is a cannabinoid drug, which acts as a potent agonist at both the CB1 and CB2 receptors, but has poor blood–brain barrier penetration, and so produces only peripheral effects at low doses, with symptoms of central effec ...

** CB-25 ** CB-52 ** CB-86 ** CB-86 ** CBS-0550 ** CP 47,497 ** CP 55,244 ** CP 55,940 ** CUMYL-5F-PICA ** CUMYL-BICA ** CUMYL-PICA ** CUMYL-PINACA ** CUMYL-THPINACA **

Dexanabinol Dexanabinol (HU-211 or ETS2101) is a synthetic cannabinoid derivative in development by e-Therapeutics plc. It is the "unnatural" enantiomer of the potent cannabinoid agonist HU-210. Unlike other cannabinoid derivatives, HU-211 does not act as a ...

, also known as 'HU-211' ** Dimethylheptylpyran, also known as 'DMHP' ** Drinabant, also known as 'AVE1625' ** Dronabinol ** EAM-2201 ** EMB-FUBINACA **

FAB-144 FAB-144 is an indazole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a designer drug. It is the indazole analogue of XLR-11. Legal status Sweden's public health agency ...

** FDU-NNE1 ** FDU-PB-22 ** FUB-144 ** FUB-APINACA **

FUB-JWH-018 FUB-JWH-018 (also known as FUB-018) is a naphthoylindole-based synthetic cannabinoid, representing a molecular hybrid of JWH-018 and AB-FUBICA or ADB-FUBICA. Legal status In the United States, all CB1 receptor agonists of the 3-(1-naphthoyl)ind ...

** FUB-PB-22 ** FUBIMINA ** Genistein **

GW-405,833 GW-405,833 (L-768,242) is a drug that acts as a potent and selective partial agonist for the cannabinoid receptor subtype CB2, with an EC50 of 0.65 nM and selectivity of around 1200x for CB2 over CB1 receptors. Animal studies have shown i ...

, also known as 'L-768,242' ** GW-842,166X ** Hemopressin ** HU-210 ** HU-243 ** HU-308 ** HU-320 ** HU-331 **

HU-336 HU-336 is a strongly antiangiogenic compound, significantly inhibiting angiogenesis at concentrations as low as 300 nM. It inhibits angiogenesis by directly inducing apoptosis of vascular endothelial cells without changing the expression of ...

HU-345 HU-345 (cannabinol quinone) is a drug that is able to inhibit aortic ring angiogenesis more potently than its parent compound cannabinol (CBN). It exhibits no psychoactive effects on the body. HU-345 can be derived through the oxidative degr ...

** HU-910 **

Ibipinabant Ibipinabant (SLV319, BMS-646,256) is a drug used in scientific research which acts as a potent and highly selective CB1 antagonist. It has potent anorectic effects in animals, and was researched for the treatment of obesity, although CB1 antagon ...

, also known as 'SLV319' **

IDFP IDFP is an organophosphorus compound related to the nerve agent sarin. Like sarin, IDFP is an irreversible inhibitor for a number of different enzymes that normally serve to break down neurotransmitters, however the long alkyl chain of IDFP make ...

** JNJ 1661010 **

JTE-907 JTE-907 is a drug used in scientific research that acts as a selective CB2 inverse agonist. It has antiinflammatory effects in animal studies, thought to be mediated by an interaction between the CB2 receptor and IgE Immunoglobulin E (IgE) ...

** JTE 7-31 ** JWH-007 ** JWH-015 ** JWH-018 ** JWH-019 **

JWH-030 JWH-030 is a research chemical which is a cannabinoid receptor agonist. It has analgesic effects and is used in scientific research. It is a partial agonist at Cannabinoid receptor type 1, CB1 receptors, with a Dissociation constant, Ki of 87 ...

** JWH-051 ** JWH-073 ** JWH-081 **

JWH-098 JWH-098 is a synthetic cannabinoid receptor agonist from the naphthoylindole family. It is the indole 2-methyl derivative of a closely related compound JWH-081, but has markedly different affinity for the CB1 and CB2 receptors. While JWH-081 is ...

JWH-116 JWH-116 is a synthetic cannabinoid receptor ligand from the naphthoylindole family. It is the indole 2-ethyl derivative of related compound JWH-018. The binding affinity of JWH-116 for the CB1 receptor is reported as Ki = 52 ± 5 nM. In the Unit ...

** JWH-122 **

JWH-133 JWH-133 (Dimethylbutyl-deoxy-Delta-8-THC) is a potent selective CB2 receptor agonist with a Ki of 3.4nM and selectivity of around 200x for CB2 over CB1 receptors. It was discovered by and named after, John W. Huffman. It's important to note t ...

** JWH-139 **

JWH-147 JWH-147 is an analgesic drug used in scientific research, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors. It is somewhat selective for the CB2 subtype, with a Ki of 11.0 nM at CB1 vs 7.1 nM at CB2. It was disco ...

** JWH-149 ** JWH-161 ** JWH-164 ** JWH-167 **

JWH-175 JWH-175 is a drug from the naphthylmethylindole family which acts as a cannabinoid receptor agonist. It was invented by the scientist John W. Huffman and colleagues at Clemson University. JWH-175 is closely related to the widely used cannabinoi ...

JWH-176 JWH-176 is an analgesic drug which acts as a cannabinoid receptor agonist. Its binding affinity at the CB1 receptor is 26.0 nM, making it more potent than THC itself, however JWH-176 is particularly notable in that it is a hydrocarbon cont ...

** JWH-182 **

JWH-184 JWH-184 is a synthetic cannabinoid receptor ligand from the naphthylmethylindole family. It is the carbonyl-reduced derivative of related compound JWH-122. The binding affinity of JWH-184 for the CB1 receptor is reported as Ki = 23 ± 6 nM. In ...

JWH-185 JWH-185 is a synthetic cannabinoid receptor ligand from the naphthoylindole family. It is the carbonyl-reduced derivative of related compound JWH-081. The binding affinity of JWH-185 for the CB1 receptor is reported as Ki = 17 ± 3 nM. In the ...

** JWH-192 ** JWH-193 ** JWH-194 ** JWH-195 ** JWH-196 ** JWH-197 ** JWH-198 ** JWH-199 ** JWH-200 ** JWH-203 ** JWH-210 ** JWH-229 ** JWH-249 ** JWH-250 ** JWH-251 ** JWH-302 **

JWH-307 JWH-307 is an analgesic drug used in scientific research, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors. It is somewhat selective for the CB2 subtype, with a Ki of 7.7 nM at CB1 vs 3.3 nM at CB2. It was disco ...

JWH-359 JWH-359 is a dibenzopyran "classical" cannabinoid drug, which is a potent and selective CB2 receptor agonist, with a Ki of 13.0 nM and selectivity of around 220 times for CB2 over CB1 receptors. It is related to other dibenzopyran CB2 ago ...

JWH-369 JWH-369 ((5-(2-chlorophenyl)-1-pentyl-1H-pyrrol-3-yl)(naphthalen-1-yl)methanone) is a synthetic cannabinoid from the naphthoylpyrrole family which acts as a potent agonist of the CB1 (Ki = 7.9 ± 0.4nM) and CB2 (Ki = 5.2 ± 0.3nM) receptors, w ...

** JWH-370 ** JWH-398 ** JWH-424 **

JZL184 JZL184 is an irreversible inhibitor for monoacylglycerol lipase (MAGL), the primary enzyme responsible for degrading the endocannabinoid 2-arachidonoylglycerol (2-AG). It displays high selectivity for MAGL over other brain serine hydrolases, includ ...

** JZL195 ** Kaempferol **

KM-233 KM-233 is a synthetic cannabinoid drug which is a structural analog of Δ8-tetrahydrocannabinol (THC), the less active but more stable isomer of the active component of ''Cannabis''. KM-233 differs from Δ8-THC by the pentyl side chain being r ...

L-759,633 L-759,633 is an analgesic drug that is a cannabinoid agonist. It is a fairly selective agonist for the CB2 receptor, with selectivity of 163x for CB2 over CB1. It produces some similar effects to other cannabinoid agonists such as analgesia, b ...

L-759,656 L-759,656 is an analgesic drug that is a cannabinoid agonist. It is a highly selective agonist for the CB2 receptor, with selectivity of 414x for CB2 over CB1, although it is still not as selective as newer agents such as HU-308. It produces ...

** LASSBio-881 ** LBP-1 **

Leelamine Leelamine (dehydroabietylamine) is a diterpene amine that has weak affinity for the cannabinoid receptors CB1 and CB2, as well as being an inhibitor of pyruvate dehydrogenase kinase. Optically active leelamine is also used as a chiral resolvin ...

Levonantradol Levonantradol (CP 50,556-1) is a synthetic cannabinoid analog of dronabinol (Marinol) developed by Pfizer in the 1980s. It is around 30x more potent than THC, and exhibits antiemetic and analgesic effects via activation of CB1 and CB2 cannabinoi ...

, also known as 'CP 50,5561' ** LH-21 ** LY-320,135 ** LY-2183240 ** MAM-2201 ** MDA-7 **

MDA-19 MDA-19 (also known as BZO-HEXOXIZID) is a drug that acts as a potent and selective agonist for the cannabinoid receptor CB2, with reasonable selectivity over the psychoactive CB1 receptor, though with some variation between species. In animal st ...

** MDA-77 ** MDMB-CHMICA ** MDMB-CHMINACA ** MDMB-FUBINACA ** Menabitan ** MEPIRAPIM **

Methanandamide Methanandamide (AM-356) is a Organic compound#Synthetic compounds, synthetically created stable Chiral (chemistry), chiral Structural analog, analog of anandamide. Its effects have been observed to act on the cannabinoid receptors (specifically o ...

, also known as 'AM-356' ** MJ-15 ** MK-9470 ** MMB-2201 **

MN-18 MN 18 is an indazole-based synthetic cannabinoid that is an agonist for the cannabinoid receptors, with ''K''i values of 45.72 nM at CB1 and 11.098 nM at CB2 and EC50 values of 2.028 nM at CB1 and 1.233 nM at CB2, and has ...

** MN-25, also known as 'UR-12' ** Nabazenil ** Nabilone **

Nabitan Nabitan (Nabutam, Benzopyranoperidine, SP-106, Abbott 40656) is a synthetic cannabinoid analog of dronabinol (Marinol). It exhibits antiemetic and analgesic effects, most likely by binding to and activating the CB1 and CB2 cannabinoid receptors, ...

** Naboctate **

NESS-0327 NESS-0327 is a drug used in scientific research which acts as an extremely potent and selective antagonist of the cannabinoid receptor CB1. It is much more potent an antagonist, and more selective for the CB1 receptor over CB2, than the more com ...

NESS-040C5 NESS-040C5 is a potent cannabinoid agonist which was developed for the treatment of glaucoma. It has reasonable selectivity for the CB2 receptor subtype, having a CB2 affinity of 0.4nM, and 25x selectivity over the related CB1 receptor. See a ...

** NIDA-41020 ** NM-2201 ** NMP-7 ** NNE1 ** Nonabine ** O-224 ** O-581 ** O-585 ** O-606 ** O-689 ** O-774 **

O-806 O-806 is a drug which is a cannabinoid derivative that is used in scientific research. It is described as a mixed agonist/antagonist at the cannabinoid receptor Receptor may refer to: * Sensory receptor, in physiology, any structure which, on ...

O-823 O-823 is a drug which is a cannabinoid derivative that is used in scientific research. It is described as a mixed agonist/antagonist at the cannabinoid receptor Receptor may refer to: * Sensory receptor, in physiology, any structure which, on r ...

** O-889 ** O-1057 **

O-1125 O-1125 (3-(1,1-dimethylhexyl-6-dimethylcarboxamide)-Δ8-tetrahydrocannabinol) is a research chemical which is a cannabinoid derivative. It has analgesic An analgesic drug, also called simply an analgesic (American English), analgaesic (Britis ...

** O-1184 ** O-1191 **

O-1238 O-1238 is a drug which is a cannabinoid derivative that is used in scientific research. It is a partial agonist at the cannabinoid receptor Receptor may refer to: * Sensory receptor, in physiology, any structure which, on receiving environmenta ...

O-1248 O1 or O-1 may refer to: Aircraft *O-1 Bird Dog, an observation aircraft manufactured by Cessna *O-1 Curtiss Falcon, an observation aircraft manufactured by the Curtiss Aircraft Company * O-1 Airship, an Italian manufactured semi-rigid airship op ...

** O-1269 ** O-1270 ** O-1376 ** O-1399 ** O-1422 ** O-1601 ** O-1602 ** O-1624 **

O-1656 O-1656 is a cannabinoid agonist which was invented by Billy R Martin and Raj K Razdan at Organix Inc in 2002. It is moderately selective for the CB2 receptor with a CB1 receptor affinity of 18 nM and a CB2 receptor affinity of 2 nM. Since it ha ...

** O-1657 ** O-1660 ** O-1812 ** O-1860 ** O-1861 ** O-1871 ** O-1918 ** O-2048 ** O-2050 **

O-2093 A macron () is a diacritical mark: it is a straight bar placed above a letter, usually a vowel. Its name derives from Ancient Greek (''makrón'') "long", since it was originally used to mark long or heavy syllables in Greco-Roman metrics ...

** O-2113 ** O-2220 ** O-2365 ** O-2372 ** O-2373 ** O-2383 ** O-2426 ** O-2484 ** O-2545 **

O-2654 A macron () is a diacritical mark: it is a straight bar placed above a letter, usually a vowel. Its name derives from Ancient Greek (''makrón'') "long", since it was originally used to mark long or heavy syllables in Greco-Roman metrics ...

** O-2694 ** O-2715 ** O-2716 ** O-3223 ** O-3226 **

Oleoylethanolamide Oleoylethanolamide (OEA) is an endogenous peroxisome proliferator-activated receptor alpha ( PPAR-α) agonist. It is a naturally occurring ethanolamide lipid that regulates feeding and body weight in vertebrates ranging from mice to pythons. O ...

, also known as 'OEA' ** Olvanil ** Org 27569 ** Org 27759 ** Org 28312 ** Org 28611 ** Org 29647 ** Otenabant, also known as 'CP-945,598' ** Palmitoylethanolamide, also known as 'PEA' ** Parahexyl ** PF-03550096 ** PF-04457845 ** PF-622 ** PF-750 ** PF-3845 ** PF-514273 ** PHOP ** PipISB ** Pirnabine ** Pravadoline ** Pregnenolone ** PSB-SB-487 ** PSB-SB-1202 ** PTI-1 ** PTI-2 ** PX-1 ** PX-2 ** PX-3 ** QUCHIC, also known as 'BB-22' ** QUPIC, also known as 'PB-22' ** RCS-4 ** RCS-8 ** Rimonabant, also known as 'SR141716' ** Rosonabant, also known as 'E-6776' ** RTI-371 ** S-444,823 ** SDB-006 ** SER-601 ** SPA-229 ** SR-144,528 ** STS-135 (drug), STS-135 ** Surinabant, also known as 'SR147778' ** Taranabant, also known as 'MK-0364' ** Tedalinab ** THC-O-acetate ** THC-O-phosphate ** THJ-018 ** THJ-2201 ** Tinabinol ** TM-38837 ** UR-144 ** URB-447 ** URB447, URB-447 ** URB597, URB-597 ** URB602, URB-602 ** URB754, URB-754 ** VCHSR ** VDM-11 ** VSN-16 ** WIN 54,461 ** WIN 55,212-2 ** WIN 56,098 ** XLR-11 (drug), XLR-11 ** Yangonin

Other

* Harmaline†, harmala alkaloids†, and other beta-carbolines, active constituents of ayahuasca; powerful MAOIs (can be classified as indoles) * Salvinorin A†, an opioid (κ-opioid receptor agonist), the active constituent of ''Salvia divinorum'' sage * Salvinorin B methoxymethyl ether†, a semi-synthetic analogue of the natural product salvinorin A with longer duration and increased affinity and potency at the κ-opioid receptor * Salvinorin B ethoxymethyl ether†, a semi-synthetic analogue of the natural product salvinorin A with longer duration and increased affinity and potency at the κ-opioid receptor * Piperazines, such as pFPP and TFMPP, usually classified as stimulants * Myristicin† and elemicin†, the active constituents of nutmeg * Cryogenine (Vertine)†, the active constituent of certain ''Heimia'' species * Atropine†, Hyoscine hydrobromide, scopolamine†, and hyoscyamine†, the active constituents of certain Solanaceae species * Ibotenic acid† and muscimol†, the active constituents of ''Amanita muscaria'' mushrooms

References

{{Reflist Psychedelic drugs, . Drug-related lists, Psychedelic drugs

Serotonergic psychedelics ( serotonin 5-HT2A receptor agonists)

Empathogens/entactogens ( serotonin (5-HT) releasing agents)

Cannabinoids ( CB-1 cannabinoid receptor ligands)

Other

See also

References

Serotonergic psychedelics ( serotonin 5-HT_2A receptor agonists)