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Eutylone
Eutylone (also known as β-keto-1,3-benzodioxolyl-''N''-ethylbutanamine, bk-EBDB, and ''N''-ethylbutylone) is a stimulant and empathogenic compound developed in the 1960s, which is classified as a designer drug. It was first reported to the EMCDDA in 2014 and became widespread internationally in 2019-2020 following bans on the related compound ephylone. It is not a natural, but a synthetic cathinone. In 2021, eutylone was the most common cathinone identified by the Drug Enforcement Administration in the United States. Legal status Sweden's public health agency suggested classifying eutylone as a hazardous substance, on September 25, 2019. In the United States Eutylone is considered a schedule 1 controlled substance as a positional isomer of Pentylonehttps://www.deadiversion.usdoj.gov/schedules/orangebook/orangebook.pdf See also * 5-Methylethylone * Butylone * Ethyl-J * Ethylone * Ephylone ''N''-Ethylpentylone (β-keto-ethylbenzodioxolylpentanamine, βk-ethyl-K, βk-E ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cathinones
Substituted cathinones, which include some stimulants and entactogens, are derivatives of cathinone. They feature a phenethylamine core with an alkyl group attached to the alpha carbon, and a ketone group attached to the beta carbon, along with additional substitutions. Cathinone occurs naturally in the plant khat whose leaves are chewed as a recreational drug. List of substituted cathinones The derivatives may be produced by substitutions at four locations of the cathinone molecule: * R1 = hydrogen, or any combination of one or more alkyl, alkoxy, alkylenedioxy, haloalkyl or halide substituents * R2 = hydrogen or any alkyl group * R3 = hydrogen, any alkyl group, or incorporation in a cyclic structure * R4 = hydrogen, any alkyl group, or incorporation in a cyclic structure The following table displays notable derivatives that have been reported: Legality On 2 April 2010, the Advisory Council on the Misuse of Drugs in the UK announced that a broad structure-based b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ethyl-J
Ethylbenzodioxolylbutanamine (EBDB; Ethyl-J) is a lesser-known entactogen, stimulant, and psychedelic. It is the ''N''-ethyl analogue of benzodioxylbutanamine (BDB; "J"), and also the α-ethyl analogue of methylenedioxyethylamphetamine (MDEA; "Eve"). EBDB was first synthesized by Alexander Shulgin. In his book '' PiHKAL'', the minimum dosage consumed was 90 mg, and the duration is unknown. EBDB produced few to no effects at the dosage range tested in ''PiHKAL'', but at higher doses of several hundred milligrams it produces euphoric effects similar to those of methylbenzodioxylbutanamine (MBDB; "Eden", "Methyl-J"), although milder and shorter lasting. Very little data exists about the pharmacological properties, metabolism, and toxicity of EBDB. See also * Methylbenzodioxolylbutanamine (MBDB; Methyl-J) * Ethylbenzodioxolylpentanamine (EBDP; Ethyl-K) * Eutylone Eutylone (also known as β-keto-1,3-benzodioxolyl-''N''-ethylbutanamine, bk-EBDB, and ''N''-ethylbutylone) is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ephylone
''N''-Ethylpentylone (β-keto-ethylbenzodioxolylpentanamine, βk-ethyl-K, βk-EBDP, ephylone) is a substituted cathinone and stimulant drug which was developed in the 1960s. It has been reported as a novel designer drug in several countries including the United Kingdom, South Africa, New Zealand, the United States, and Australia.Pill testing at festivals has hidden benefits that could reduce drug taking Claudia Long, , 2018-07-20 In 2018, ''N''-ethylpentylone was the most common drug of the cathinone class to be identified in |
Ephylone
''N''-Ethylpentylone (β-keto-ethylbenzodioxolylpentanamine, βk-ethyl-K, βk-EBDP, ephylone) is a substituted cathinone and stimulant drug which was developed in the 1960s. It has been reported as a novel designer drug in several countries including the United Kingdom, South Africa, New Zealand, the United States, and Australia.Pill testing at festivals has hidden benefits that could reduce drug taking Claudia Long, , 2018-07-20 In 2018, ''N''-ethylpentylone was the most common drug of the cathinone class to be identified in |
5-Methylethylone
5-Methylethylone (5-methyl-βk-MDEA, 5ME) is an empathogen, stimulant and psychedelic drug of the amphetamine, phenethylamine, and cathinone chemical classes. It is structurally related to ethylone, a novel designer drug. Relatively little data exists about the pharmacological properties, metabolism, and toxicity of 5-methylethylone, though it has been sold as a designer drug. Legal status United States 5-Methylethylone is unscheduled in the United States, but it is not currently approved by the Food and Drug Administration for human consumption. The state of Vermont lists it as a regulated drug. Vermont Health Regulations See also * 5-Methyl-MDA * |
N-Ethylhexylone
''N''-Ethylhexylone is a recreational designer drug from the substituted cathinone family, with stimulant effects. It was first identified in Poland in August 2019. It is illegal in Taiwan since July 2020, where it had been sold mixed with plant material under the name 彩虹菸 ("Rainbow Tobacco" or "Rainbow Smoke"). See also * 3F-NEH * 4F-PHP * 5-Methylethylone * Ethylone * Eutylone * Ephylone * Isohexylone * MDPV * MDPHP * N-Ethylhexedrone * N-Ethylheptylone ''N''-Ethylheptylone (HEP) is a recreational designer drug from the substituted cathinone family, with stimulant effects. It is a homologue of related drugs such as ethylone, eutylone, ephylone and ''N''-ethylhexylone but with a longer hepty ... References Cathinones Designer drugs Norepinephrine–dopamine reuptake inhibitors {{nervous-system-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N-Ethylhexedrone
''N''-Ethylhexedrone (also known as α-ethylaminocaprophenone, ''N''-ethylnorhexedrone, hexen, and NEH) is a stimulant of the cathinone class that acts as a norepinephrine–dopamine reuptake inhibitor (NDRI) with IC50 values of 0.0978 and 0.0467 μM, respectively. ''N''-Ethylhexedrone was first mentioned in a series of patents by Boehringer Ingelheim in the 1960s which led to the development of the better-known drug methylenedioxypyrovalerone (MDPV). Since the mid-2010s, ''N''-ethylhexedrone has been sold online as a designer drug. In 2018, ''N''-ethylhexedrone was the second most common drug of the cathinone class to be identified in Drug Enforcement Administration seizures. ''N''-Ethylhexedrone was first synthesized by Boehringer Ingelheim in 1964. It appears to have emerged on the online research chemical market in late 2015. It is an example of a novel psychoactive substance specifically chosen to mimic the features of prohibited substances and bypass drug laws. It is one ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Designer Drugs
A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests. Designer drugs include psychoactive substances that have been designated by the European Union as new psychoactive substances (NPS) as well as analogs of performance-enhancing drugs such as designer steroids. Some of these were originally synthesized by academic or industrial researchers in an effort to discover more potent derivatives with fewer side effects, and shorter duration (and possibly also because it is easier to apply for patents for new molecules) and were later co-opted for recreational use. Other designer drugs were prepared for the first time in clandestine laboratories. Because the efficacy and safety of these substances have not been thoroughly evaluated in animal and human trials, the use of some of these drugs may result i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
N-Ethylheptylone
''N''-Ethylheptylone (HEP) is a recreational designer drug from the substituted cathinone family, with stimulant effects. It is a homologue of related drugs such as ethylone, eutylone, ephylone and ''N''-ethylhexylone but with a longer heptyl side chain. It was first reported in Sweden in 2019. See also * α-PEP * 3F-NEH * 4F-PV9 * MDPHP * N-Ethylheptedrone ''N''-Ethylheptedrone is a recreational designer drug from the substituted cathinone family, with stimulant effects. It is a homologue of related drugs such as ethcathinone, ''N''-ethylbuphedrone and ''N''-ethylhexedrone but with a longer p ... References Designer drugs Cathinones {{nervous-system-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stimulant
Stimulants (also often referred to as psychostimulants or colloquially as uppers) is an overarching term that covers many drugs including those that increase activity of the central nervous system and the body, drugs that are pleasurable and invigorating, or drugs that have Sympathomimetic drug, sympathomimetic effects. Stimulants are widely used throughout the world as prescription medicines as well as without a prescription (either legally or Prohibition (drugs), illicitly) as performance-enhancing substance, performance-enhancing or recreational drug use, recreational drugs. Among narcotics, stimulants produce a noticeable crash or ''Comedown (drugs), comedown'' at the end of their effects. The most frequently prescribed stimulants as of 2013 were lisdexamfetamine (Vyvanse), methylphenidate (Ritalin), and amphetamine (Adderall). It was estimated in 2015 that the percentage of the world population that had used cocaine during a year was 0.4%. For the category "amphetamines and p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ethylone
Ethylone, also known as 3,4-methylenedioxy-''N''-ethylcathinone (MDEC, βk-MDEA), is a recreational designer drug classified as an entactogen, stimulant, and psychedelic of the phenethylamine, amphetamine, and cathinone chemical classes. It is the β-keto analogue of MDEA ("Eve"). Ethylone has only a short history of human use and is reported to be less potent than its relative methylone. In the United States, it began to be found in cathinone products in late 2011. Very little data exists about the pharmacological properties, metabolism, and toxicity of ethylone, and although several ethylone-related deaths have been reported, the cause of death was not due to ingestion of ethylone. Pharmacokinetics Analysis of human and rat urine for the metabolites of bk-amphetamines suggested that ethylone was degraded in the following metabolic steps: # N- deethylation to the primary amine. # Reduction of the keto moiety to the respective alcohol. Legal Status As of October 2015 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
