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2C-YN
2C-YN is an analog of phenethylamine that can be synthesized from 2C-I. Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-YN, although Daniel Trachsel lists it as having a dosage of around 50mg and a duration of around 2 hours, with relatively mild psychedelic effects. Legality Canada As of October 31st, 2016; 2C-YN is a controlled substance (Schedule III) in Canada. http://gazette.gc.ca/rp-pr/p2/2016/2016-05-04/html/sor-dors72-eng.php See also * 2C-AL * 2C-E * 2C-cP 2C-CP (2C-cP) is a recreational designer drug from the substituted phenethylamine family, with psychedelic effects. It was first synthesised by Daniel Trachsel and colleagues in 2006. It has a binding affinity (Ki) of 95 nM at the seroton ... * 2C-V References {{Hallucinogenic phenethylamines 2C (psychedelics) Ethynyl compounds ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2C (psychedelics)
2C (2C-''x'') is a general name for the family of psychedelic phenethylamines containing methoxy groups on the 2 and 5 positions of a benzene ring. Most of these compounds also carry lipophilic substituents at the 4 position, usually resulting in more potent and more metabolically stable and longer acting compounds. Most of the currently known 2C compounds were first synthesized by Alexander Shulgin in the 1970s and 1980s and published in his book '' PiHKAL'' (''Phenethylamines i Have Known And Loved''). Shulgin also coined the term 2C, being an acronym for the 2 carbon atoms between the benzene ring and the amino group. Legality Canada As of October 12, 2016, the 2C-''x'' family of substituted phenethylamines is a controlled substance (Schedule III) in Canada. See also * Substituted phenethylamines * Substituted amphetamines * Substituted methylenedioxyphenethylamines * DOx, 25-NB * Substituted tryptamine Substituted tryptamines, or serotonin analogues, are organic comp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2C-AL
2C-AL is a drug from the substituted phenethylamine Substituted phenethylamines (or simply phenethylamines) are a chemical class of organic compounds that are based upon the phenethylamine structure; the class is composed of all the derivative compounds of phenethylamine which can be formed by ... family which acts as an agonist of the 5-HT2A receptor, with an EC50 of 2.15nM at 5-HT2A vs 77.71nM at 5-HT2B, and produces a head-twitch response in animal studies. It was first discussed as a hypothetical compound in Daniel Trachsel's 2013 review of the field after his successful synthesis of the related compounds 2C-V and 2C-YN, and finally synthesised by a team at Gilgamesh Pharmaceuticals in 2020 using a different synthetic route from that employed by Trachsel. See also * 2C-CP * 2C-IP * 2C-P * 2C-T-16 * Allylescaline * 3C-AL References Designer drugs Psychedelic phenethylamines Serotonin receptor agonists Methoxy compounds Allyl compounds {{nervous-syste ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2C-cP
2C-CP (2C-cP) is a recreational designer drug from the substituted phenethylamine family, with psychedelic effects. It was first synthesised by Daniel Trachsel and colleagues in 2006. It has a binding affinity (Ki) of 95 nM at the serotonin receptor 5-HT2A and 41 nM at 5-HT2C and is active at a dosage of between 15 and 35 mg with a duration of 3 to 6 hours. See also * 2C-IP * 2C-P * 2C-T-15 2C-T-15 or 2,5-dimethoxy-4-(β-cyclopropylthio)phenethylamine is a psychedelic phenethylamine of the 2C family. It was presumably first synthesized by Alexander Shulgin and reported in his book '' PiHKAL (Phenethylamines i Have Known And Loved) ... * 2C-V * 2C-YN References Designer drugs Psychedelic phenethylamines Serotonin receptor agonists Methoxy compounds Cyclopropyl compounds {{nervous-system-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2C-V
2C-V is a recreational designer drug from the substituted phenethylamine family, with psychedelic effects. It was first synthesised by Daniel Trachsel and colleagues in 2006. It is active at a dosage of 25 mg with a duration of around 5 hours. See also * 2C-AL * 2C-CP * 2C-E 2C-E is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin and documented in his book '' PiHKAL''. Like the other substances in its family, it produces sensory and cognitive effects in its physical reactio ... * 2C-YN References Designer drugs Psychedelic phenethylamines Serotonin receptor agonists Methoxy compounds Vinyl compounds {{nervous-system-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Structural Analog
A structural analog (analogue in modern traditional English; Commonwealth English), also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component. It can differ in one or more atoms, functional groups, or substructures, which are replaced with other atoms, groups, or substructures. A structural analog can be imagined to be formed, at least theoretically, from the other compound. Structural analogs are often isoelectronic. Despite a high chemical similarity, structural analogs are not necessarily functional analogs and can have very different physical, chemical, biochemical, or pharmacological properties. In drug discovery, either a large series of structural analogs of an initial lead compound are created and tested as part of a structure–activity relationship study or a database is screened for structural analogs of a lead compound. Chemical analogues of i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenethylamine
Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine, which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission by binding to trace amine-associated receptor 1 (TAAR1) and inhibiting vesicular monoamine transporter 2 (VMAT2) in monoamine neurons. To a lesser extent, it also acts as a neurotransmitter in the human central nervous system. In mammals, phenethylamine is produced from the amino acid L-phenylalanine by the enzyme aromatic L-amino acid decarboxylase via enzymatic decarboxylation. In addition to its presence in mammals, phenethylamine is found in many other organisms and foods, such as chocolate, especially after microbial fermentation. Phenethylamine is sold as a dietary supplement for purported mood and weight loss-related therapeutic benefits; however, in orally ingested phenethylamine, a significant amount is metabolized in the small intestine by monoa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2C-I
2C-I is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin and described in his 1991 book '' PiHKAL'' (''Phenethylamines I Have Known and Loved''). The drug has been used recreationally as psychedelic and other reported effects and was sometimes confused with the more potent chemical cousin 25I-NBOMe, nicknamed "Smiles," in the media.Weiss, Piper (September 20, 2012)2C-I or 'Smiles': The New Killer Drug Every Parent Should Know About.''Yahoo! News''Mackin, Teresa (October 9, 2012)Dangerous synthetic drug making its way across the country. WISH-TV Recreational use In the early 2000s, 2C-I was sold in Dutch smart shops after the drug 2C-B was banned. According to the US Drug Enforcement Administration, 2C-I is taken orally or snorted in a powder form.Reuters (March 20, 2011)Synthetic drug, subject of proposed bans, kill teen./ref> Drug prohibition laws European Union In December 2003, the European Council issued a binding order compell ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2C-E
2C-E is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin and documented in his book '' PiHKAL''. Like the other substances in its family, it produces sensory and cognitive effects in its physical reactions with living organisms. Properties 2,5-Dimethoxy-4-ethylphenethylamine is a colorless oil. Crystalline forms are obtained as the amine salt by reacting the free base with a mineral acid, typically hydrochloric acid (HCl). Shulgin does not report an exact boiling point for the free base, stating only that during one synthesis the fraction boiling between 90 and 100 °C at 0.25 mmHg pressure was collected and converted to the hydrochloride salt. Shulgin reports the melting point of the hydrochloride salt as 208.5–210.5 °C. Effects According to Shulgin, the duration of 2C-E's effects is generally between six and ten hours for an average dose, with the plateau lasting between three and six hours. 2C-E's effects are o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
