Isaac Witz
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Isaac Witz
Isaac P. Witz (born November 7, 1934) is an Israeli Immunologist and cancer researcher, who is professor Emeritus at the Shmunis School of Biomedicine and Cancer Research in Tel Aviv University (TAU), where he was formerly the vice president for Research and Development and the Dean of Faculty of Life Sciences. He is one of the scientists who laid the foundations of the tumor microenvironment (TME) research field. Biography Isaac Witz was born in Vienna. In September 1939 he immigrated with his parents to Palestine which was administered by a British-held mandate. In 1952, Witz joined the Israeli Defense Forces, where he served as an officer in the armored forces. He did his reserve service in the medical corps. Soon after his discharge, he initiated his Masters studies in Microbiology, Biochemistry and Parasitology which he completed in 1959. He then started his Doctoral studies in on various aspects of Cancer Immunology at the Hebrew University of Jerusalem – Hadassa ...
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Vienna
en, Viennese , iso_code = AT-9 , registration_plate = W , postal_code_type = Postal code , postal_code = , timezone = CET , utc_offset = +1 , timezone_DST = CEST , utc_offset_DST = +2 , blank_name = Vehicle registration , blank_info = W , blank1_name = GDP , blank1_info = € 96.5 billion (2020) , blank2_name = GDP per capita , blank2_info = € 50,400 (2020) , blank_name_sec1 = HDI (2019) , blank_info_sec1 = 0.947 · 1st of 9 , blank3_name = Seats in the Federal Council , blank3_info = , blank_name_sec2 = GeoTLD , blank_info_sec2 = .wien , website = , footnotes = , image_blank_emblem = Wien logo.svg , blank_emblem_size = Vienna ( ; german: Wien ; ba ...
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Immunochemist
Immunochemistry is the study of the chemistry of the immune system. This involves the study of the properties, functions, interactions and production of the chemical components (antibodies/immunoglobulins, toxin, epitopes of proteins like CD4, antitoxins, cytokines/chemokines, antigens) of the immune system. It also include immune responses and determination of immune materials/products by immunochemical assays. In addition, immunochemistry is the study of the identities and functions of the components of the immune system. Immunochemistry is also used to describe the application of immune system components, in particular antibodies, to chemically labelled antigen molecules for visualization. Various methods in immunochemistry have been developed and refined, and used in scientific study, from virology to molecular evolution. Immunochemical techniques include: enzyme-linked immunosorbent assay, immunoblotting (e.g., Western blot assay), precipitation and agglutination react ...
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Metastasis
Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; the term is typically used when referring to metastasis by a cancerous tumor. The newly pathological sites, then, are metastases (mets). It is generally distinguished from cancer invasion, which is the direct extension and penetration by cancer cells into neighboring tissues. Cancer occurs after cells are genetically altered to proliferate rapidly and indefinitely. This uncontrolled proliferation by mitosis produces a primary heterogeneic tumour. The cells which constitute the tumor eventually undergo metaplasia, followed by dysplasia then anaplasia, resulting in a malignant phenotype. This malignancy allows for invasion into the circulation, followed by invasion to a second site for tumorigenesis. Some cancer cells known as circulating tumor cells acquire the ability to penetrate the walls of lymphatic or blood vessels, after which they are abl ...
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Antibodies
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen. Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can ''tag'' a microbe or an infected cell for attack by other parts of the immune system, or can neutralize it directly (for example, by blocking a part of a virus that is essential for its invasion). To allow the immune system to recognize millions of different antigens, the antigen-binding sites at both tips of the antibody come in an equally wide variety. In contrast, the remainder of the antibody is relatively constant. It only occurs in a few vari ...
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Tel Aviv
Tel Aviv-Yafo ( he, תֵּל־אָבִיב-יָפוֹ, translit=Tēl-ʾĀvīv-Yāfō ; ar, تَلّ أَبِيب – يَافَا, translit=Tall ʾAbīb-Yāfā, links=no), often referred to as just Tel Aviv, is the most populous city in the Gush Dan metropolitan area of Israel. Located on the Israeli coastal plain, Israeli Mediterranean coastline and with a population of , it is the Economy of Israel, economic and Technology of Israel, technological center of the country. If East Jerusalem is considered part of Israel, Tel Aviv is the country's second most populous city after Jerusalem; if not, Tel Aviv is the most populous city ahead of West Jerusalem. Tel Aviv is governed by the Tel Aviv-Yafo Municipality, headed by Mayor Ron Huldai, and is home to many List of diplomatic missions in Israel, foreign embassies. It is a Global city, beta+ world city and is ranked 57th in the 2022 Global Financial Centres Index. Tel Aviv has the List of cities by GDP, third- or fourth-largest e ...
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Suzhou
Suzhou (; ; Suzhounese: ''sou¹ tseu¹'' , Mandarin: ), alternately romanized as Soochow, is a major city in southern Jiangsu province, East China. Suzhou is the largest city in Jiangsu, and a major economic center and focal point of trade and commerce. Administratively, Suzhou is a prefecture-level city with a population of 6,715,559 in the city proper, and a total resident population of 12,748,262 as of the 2020 census in its administrative area. The city jurisdiction area's north waterfront is on a lower reach of the Yangtze whereas it has its more focal south-western waterfront on Lake Tai – crossed by several waterways, its district belongs to the Yangtze River Delta region. Suzhou is now part of the Greater Shanghai metro area, incorporating most of Changzhou, Wuxi and Suzhou urban districts plus Kunshan and Taicang, with a population of more than 38,000,000 residents as of 2020. Its urban population grew at an unprecedented rate of 6.5% between 2000 and 2014, which ...
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Versailles
The Palace of Versailles ( ; french: Château de Versailles ) is a former royal residence built by King Louis XIV located in Versailles, about west of Paris, France. The palace is owned by the French Republic and since 1995 has been managed, under the direction of the French Ministry of Culture, by the Public Establishment of the Palace, Museum and National Estate of Versailles. Some 15,000,000 people visit the palace, park, or gardens of Versailles every year, making it one of the most popular tourist attractions in the world. Louis XIII built a simple hunting lodge on the site of the Palace of Versailles in 1623 and replaced it with a small château in 1631–34. Louis XIV expanded the château into a palace in several phases from 1661 to 1715. It was a favorite residence for both kings, and in 1682, Louis XIV moved the seat of his court and government to Versailles, making the palace the ''de facto'' capital of France. This state of affairs was continued by Kings Louis XV an ...
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Florence
Florence ( ; it, Firenze ) is a city in Central Italy and the capital city of the Tuscany region. It is the most populated city in Tuscany, with 383,083 inhabitants in 2016, and over 1,520,000 in its metropolitan area.Bilancio demografico anno 2013, datISTAT/ref> Florence was a centre of medieval European trade and finance and one of the wealthiest cities of that era. It is considered by many academics to have been the birthplace of the Renaissance, becoming a major artistic, cultural, commercial, political, economic and financial center. During this time, Florence rose to a position of enormous influence in Italy, Europe, and beyond. Its turbulent political history includes periods of rule by the powerful Medici family and numerous religious and republican revolutions. From 1865 to 1871 the city served as the capital of the Kingdom of Italy (established in 1861). The Florentine dialect forms the base of Standard Italian and it became the language of culture throughout Ital ...
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Prague
Prague ( ; cs, Praha ; german: Prag, ; la, Praga) is the capital and largest city in the Czech Republic, and the historical capital of Bohemia. On the Vltava river, Prague is home to about 1.3 million people. The city has a temperate oceanic climate, with relatively warm summers and chilly winters. Prague is a political, cultural, and economic hub of central Europe, with a rich history and Romanesque, Gothic, Renaissance and Baroque architectures. It was the capital of the Kingdom of Bohemia and residence of several Holy Roman Emperors, most notably Charles IV (r. 1346–1378). It was an important city to the Habsburg monarchy and Austro-Hungarian Empire. The city played major roles in the Bohemian and the Protestant Reformations, the Thirty Years' War and in 20th-century history as the capital of Czechoslovakia between the World Wars and the post-war Communist era. Prague is home to a number of well-known cultural attractions, many of which survived the ...
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Sea Of Galilee
The Sea of Galilee ( he, יָם כִּנֶּרֶת, Judeo-Aramaic: יַמּא דטבריא, גִּנֵּיסַר, ar, بحيرة طبريا), also called Lake Tiberias, Kinneret or Kinnereth, is a freshwater lake in Israel. It is the lowest freshwater lake on Earth and the second-lowest lake in the world (after the Dead Sea, a saltwater lake), at levels between and below sea level. It is approximately in circumference, about long, and wide. Its area is at its fullest, and its maximum depth is approximately .Data Summary: Lake Kinneret (Sea of Galilee)
The lake is fed partly by underground springs, but its main source is the

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Stockholm
Stockholm () is the Capital city, capital and List of urban areas in Sweden by population, largest city of Sweden as well as the List of urban areas in the Nordic countries, largest urban area in Scandinavia. Approximately 980,000 people live in the Stockholm Municipality, municipality, with 1.6 million in the Stockholm urban area, urban area, and 2.4 million in the Metropolitan Stockholm, metropolitan area. The city stretches across fourteen islands where Mälaren, Lake Mälaren flows into the Baltic Sea. Outside the city to the east, and along the coast, is the island chain of the Stockholm archipelago. The area has been settled since the Stone Age, in the 6th millennium BC, and was founded as a city in 1252 by Swedish statesman Birger Jarl. It is also the county seat of Stockholm County. For several hundred years, Stockholm was the capital of Finland as well (), which then was a part of Sweden. The population of the municipality of Stockholm is expected to reach o ...
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Karolinska Institute
The Karolinska Institute (KI; sv, Karolinska Institutet; sometimes known as the (Royal) Caroline Institute in English) is a research-led medical university in Solna within the Stockholm urban area of Sweden. The Karolinska Institute is consistently ranked amongst the world's best medical schools, ranking 6th worldwide for medicine in 2021. The Nobel Assembly at the Karolinska Institute awards the Nobel Prize in Physiology or Medicine. The assembly consists of fifty professors from various medical disciplines at the university. The current rector of Karolinska Institute is Ole Petter Ottersen, who took office in August 2017. The Karolinska Institute was founded in 1810 on the island of Kungsholmen on the west side of Stockholm; the main campus was relocated decades later to Solna, just outside Stockholm. A second campus was established more recently in Flemingsberg, Huddinge, south of Stockholm. The Karolinska Institute is Sweden's third oldest medical school, after Uppsala ...
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