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Mariano Santo
Mariano Santo (1488 in Barletta – 1577 in Rome) was a prominent surgeon of the 16th century. He was born and raised in Barletta in 1488 and relocated to Rome in 1510 to study medicine. Following this, he became a surgeon and taught at Bologna University. Eventually he returned to Baletta in 1520 for the death of his father and married Maddalena Braccio shortly after in 1524. Maddalena bore Mariano 4 sons and in 1526 they moved to Milan and in 1527 they again move settling in Ragusa (today Dubrovnik). He operated on battlefields during the war between Austria and Ottomans, and finally went to Venice. Mariano’s written work includes the ''Artium et medicine'' and the very important ''Libellus Aureus de lapide a vesica per incisionem extrahendo'' and the ''De lapide renum''. Additionally, he was the first in Europe to demonstrate a new surgical technique called "sectio mariana", which employs the use of a new tool, the "esploratorium", for the extraction of renal calculi ...
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Mariano Santo
Mariano Santo (1488 in Barletta – 1577 in Rome) was a prominent surgeon of the 16th century. He was born and raised in Barletta in 1488 and relocated to Rome in 1510 to study medicine. Following this, he became a surgeon and taught at Bologna University. Eventually he returned to Baletta in 1520 for the death of his father and married Maddalena Braccio shortly after in 1524. Maddalena bore Mariano 4 sons and in 1526 they moved to Milan and in 1527 they again move settling in Ragusa (today Dubrovnik). He operated on battlefields during the war between Austria and Ottomans, and finally went to Venice. Mariano’s written work includes the ''Artium et medicine'' and the very important ''Libellus Aureus de lapide a vesica per incisionem extrahendo'' and the ''De lapide renum''. Additionally, he was the first in Europe to demonstrate a new surgical technique called "sectio mariana", which employs the use of a new tool, the "esploratorium", for the extraction of renal calculi ...
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Libellus Aureus
A ''libellus'' (plural ''libelli'') in the Roman Empire was any brief document written on individual pages (as opposed to scrolls or tablets), particularly official documents issued by governmental authorities. The term ''libellus'' has particular historical significance for the libelli that were issued during the reign of Emperor Decius to citizens to certify performance of required pagan sacrifices in order to demonstrate loyalty to the authorities of the Roman Empire. During later periods libelli were issued as certificates of indulgence, in which the confessors or martyrs interceded for apostate Christians. Etymology The word ''libellus'' is a Latin diminutive form of the ordinary word ''liber'' (meaning "book"), from which we get the English word ''library''. Literally, it means "little book". Sometimes the word was used to describe what we would call: essays, tracts, pamphlets, or petitions. History During the Decian persecution In the year 250, in an attempt to promote tra ...
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Barletta
Barletta () is a city, ''comune'' of Apulia, in south eastern Italy. Barletta is the capoluogo, together with Andria and Trani, of the Province of Barletta-Andria-Trani. It has a population of around 94,700 citizens. The city's territory belongs to the Valle dell'Ofanto. The Ofanto river crosses the countryside and forms the border between the territory of Barletta and that of Margherita di Savoia. The mouth of the river is in the territory of Barletta. The area of Barletta also includes part of the battlefield of Cannae. This is a very important archeological site, remembered for the major battle in 216 BCE between the Romans and the Carthaginians, won by Hannibal. The site has been recognised as Città d'Arte (''city of art'') of Apulia in the 2005 for the beautiful architecture. Cannae flourished in the Roman period and then after a series of debilitating Saracen attacks, was finally destroyed by the Normans and then abandoned in the early Middle Ages. Barletta is ho ...
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Rome
, established_title = Founded , established_date = 753 BC , founder = King Romulus (legendary) , image_map = Map of comune of Rome (metropolitan city of Capital Rome, region Lazio, Italy).svg , map_caption = The territory of the ''comune'' (''Roma Capitale'', in red) inside the Metropolitan City of Rome (''Città Metropolitana di Roma'', in yellow). The white spot in the centre is Vatican City. , pushpin_map = Italy#Europe , pushpin_map_caption = Location within Italy##Location within Europe , pushpin_relief = yes , coordinates = , coor_pinpoint = , subdivision_type = Country , subdivision_name = Italy , subdivision_type2 = Region , subdivision_name2 = Lazio , subdivision_type3 = Metropolitan city , subdivision_name3 = Rome Capital , government_footnotes= , government_type = Strong Mayor–Council , leader_title2 = Legislature , leader_name2 = Capitoline Assemb ...
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Bologna University
The University of Bologna ( it, Alma Mater Studiorum – Università di Bologna, UNIBO) is a public research university in Bologna, Italy. Founded in 1088 by an organised guild of students (''studiorum''), it is the oldest university in continuous operation in the world, and the first degree-awarding institution of higher learning. At its foundation, the word ''universitas'' was first coined.Hunt Janin: "The university in medieval life, 1179–1499", McFarland, 2008, , p. 55f.de Ridder-Symoens, Hilde''A History of the University in Europe: Volume 1, Universities in the Middle Ages'' Cambridge University Press, 1992, , pp. 47–55 With over 90,000 students, it is the second largest university in Italy after La Sapienza in Rome. It was the first place of study to use the term ''universitas'' for the corporations of students and masters, which came to define the institution (especially its law school) located in Bologna. The university's emblem carries the motto, ''Alma Mater Studio ...
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Milan
Milan ( , , Lombard: ; it, Milano ) is a city in northern Italy, capital of Lombardy, and the second-most populous city proper in Italy after Rome. The city proper has a population of about 1.4 million, while its metropolitan city has 3.26 million inhabitants. Its continuously built-up urban area (whose outer suburbs extend well beyond the boundaries of the administrative metropolitan city and even stretch into the nearby country of Switzerland) is the fourth largest in the EU with 5.27 million inhabitants. According to national sources, the population within the wider Milan metropolitan area (also known as Greater Milan), is estimated between 8.2 million and 12.5 million making it by far the largest metropolitan area in Italy and one of the largest in the EU.* * * * Milan is considered a leading alpha global city, with strengths in the fields of art, chemicals, commerce, design, education, entertainment, fashion, finance, healthcar ...
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Ragusa (Croatia)
Dubrovnik (), historically known as Ragusa (; see notes on naming), is a city on the Adriatic Sea in the region of Dalmatia, in the southeastern semi-exclave of Croatia. It is one of the most prominent tourist destinations in the Mediterranean, a seaport and the centre of the Dubrovnik-Neretva County. Its total population is 42,615 (2011 census). In 1979, the city of Dubrovnik was added to the UNESCO list of World Heritage Sites in recognition of its outstanding medieval architecture and fortified old town. The history of the city probably dates back to the 7th century, when the town known as was founded by refugees from Epidaurum (). It was under the protection of the Byzantine Empire and later under the sovereignty of the Republic of Venice. Between the 14th and 19th centuries, Dubrovnik ruled itself as a free state. The prosperity of the city was historically based on maritime trade; as the capital of the maritime Republic of Ragusa, it achieved a high level of development ...
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Dubrovnik
Dubrovnik (), historically known as Ragusa (; see notes on naming), is a city on the Adriatic Sea in the region of Dalmatia, in the southeastern semi-exclave of Croatia. It is one of the most prominent tourist destinations in the Mediterranean, a seaport and the centre of the Dubrovnik-Neretva County. Its total population is 42,615 (2011 census). In 1979, the city of Dubrovnik was added to the UNESCO list of World Heritage Sites in recognition of its outstanding medieval architecture and fortified old town. The history of the city probably dates back to the 7th century, when the town known as was founded by refugees from Epidaurum (). It was under the protection of the Byzantine Empire and later under the sovereignty of the Republic of Venice. Between the 14th and 19th centuries, Dubrovnik ruled itself as a free state. The prosperity of the city was historically based on maritime trade; as the capital of the maritime Republic of Ragusa, it achieved a high level of develo ...
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Austria
Austria, , bar, Östareich officially the Republic of Austria, is a country in the southern part of Central Europe, lying in the Eastern Alps. It is a federation of nine states, one of which is the capital, Vienna, the most populous city and state. A landlocked country, Austria is bordered by Germany to the northwest, the Czech Republic to the north, Slovakia to the northeast, Hungary to the east, Slovenia and Italy to the south, and Switzerland and Liechtenstein to the west. The country occupies an area of and has a population of 9 million. Austria emerged from the remnants of the Eastern and Hungarian March at the end of the first millennium. Originally a margraviate of Bavaria, it developed into a duchy of the Holy Roman Empire in 1156 and was later made an archduchy in 1453. In the 16th century, Vienna began serving as the empire's administrative capital and Austria thus became the heartland of the Habsburg monarchy. After the dissolution of the H ...
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Ottomans
The Ottoman Turks ( tr, Osmanlı Türkleri), were the Turkic founding and sociopolitically the most dominant ethnic group of the Ottoman Empire ( 1299/1302–1922). Reliable information about the early history of Ottoman Turks remains scarce, but they take their Turkish name, ''Osmanlı'' ("Osman" became altered in some European languages as "Ottoman"), from the house of Osman I (reigned 1299–1326), the founder of the House of Osman, the ruling dynasty of the Ottoman Empire for its entire 624 years. Expanding from its base in Söğüt, the Ottoman principality began incorporating other Turkish-speaking Muslims and non-Turkish Christians. Crossing into Europe from the 1350s, coming to dominate the Mediterranean Sea and, in 1453, invading Constantinople (the capital city of the Byzantine Empire), the Ottoman Turks blocked all major land routes between Asia and Europe. Western Europeans had to find other ways to trade with the East. Brief history The "Ottomans" first ...
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Venice
Venice ( ; it, Venezia ; vec, Venesia or ) is a city in northeastern Italy and the capital of the Veneto Regions of Italy, region. It is built on a group of 118 small islands that are separated by canals and linked by over 400 bridges. The islands are in the shallow Venetian Lagoon, an enclosed bay lying between the mouths of the Po River, Po and the Piave River, Piave rivers (more exactly between the Brenta (river), Brenta and the Sile (river), Sile). In 2020, around 258,685 people resided in greater Venice or the ''Comune di Venezia'', of whom around 55,000 live in the historical island city of Venice (''centro storico'') and the rest on the mainland (''terraferma''). Together with the cities of Padua, Italy, Padua and Treviso, Italy, Treviso, Venice is included in the Padua-Treviso-Venice Metropolitan Area (PATREVE), which is considered a statistical metropolitan area, with a total population of 2.6 million. The name is derived from the ancient Adri ...
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Kidney Stone Disease
Kidney stone disease, also known as nephrolithiasis or urolithiasis, is a crystallopathy where a solid piece of material (kidney stone) develops in the urinary tract. Kidney stones typically form in the kidney and leave the body in the urine stream. A small stone may pass without causing symptoms. If a stone grows to more than , it can cause blockage of the ureter, resulting in sharp and severe pain in the lower back or abdomen. A stone may also result in blood in the urine, vomiting, or painful urination. About half of people who have had a kidney stone will have another within ten years. Most stones form by a combination of genetics and environmental factors. Risk factors include high urine calcium levels, obesity, certain foods, some medications, calcium supplements, hyperparathyroidism, gout and not drinking enough fluids. Stones form in the kidney when minerals in urine are at high concentration. The diagnosis is usually based on symptoms, urine testing, and medical i ...
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