Latrodectus Variolus
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Latrodectus Variolus
''Latrodectus variolus'', the northern black widow spider or northern widow, is a venomous species of spider in the genus ''Latrodectus'' of the family Theridiidae. The population is closely related to the southern black widow, ''Latrodectus mactans'', and the western black widow, ''Latrodectus hesperus'', of the genus. In North America, the species is commonly found in Middle Atlantic states (New Jersey, Delaware, Maryland). During the April–May mating season, it can travel north along the coast as far as Massachusetts. It is also found in Connecticut in the late summer, and rarely, in southern Ontario and southern Quebec, Michigan, and at least as far northwest as parts of Wisconsin. A bite may cause latrodectism, and requires medical attention in the case of increasingly severe discomfort or spreading local redness accompanied by severe pain. The LD-50 has been measured in mice as ; each spider contains about of venom. Unlike for the related ''Latrodectus mactans'', no an ...
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Charles Athanase Walckenaer
Baron Charles Athanase Walckenaer (25 December 1771 – 28 April 1852) was a French civil servant and scientist. Biography Walckenaer was born in Paris and studied at the universities of University of Oxford, Oxford and University of Glasgow, Glasgow. In 1793 he was appointed head of the military transports in the Pyrenees, after which he pursued technical studies at the École Nationale des Ponts et Chaussées and the École polytechnique. He was elected member of the Institut de France in 1813, was mayor (''maire'') in the 5th arrondissement of Paris, 5th arrondissement in Paris and secretary-general of the prefect of the Seine (département), Seine 1816–1825. He was made a baron in 1823. In 1839 he was appointed conservator for the Department of Maps at the Bibliothèque Nationale, Royal Library in Paris and in 1840 secretary for life in the Académie des Inscriptions et Belles Lettres. He was one of the founders of the Société entomologique de France in 1832, and a "r ...
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Connecticut
Connecticut () is the southernmost state in the New England region of the Northeastern United States. It is bordered by Rhode Island to the east, Massachusetts to the north, New York to the west, and Long Island Sound to the south. Its capital is Hartford and its most populous city is Bridgeport. Historically the state is part of New England as well as the tri-state area with New York and New Jersey. The state is named for the Connecticut River which approximately bisects the state. The word "Connecticut" is derived from various anglicized spellings of "Quinnetuket”, a Mohegan-Pequot word for "long tidal river". Connecticut's first European settlers were Dutchmen who established a small, short-lived settlement called House of Hope in Hartford at the confluence of the Park and Connecticut Rivers. Half of Connecticut was initially claimed by the Dutch colony New Netherland, which included much of the land between the Connecticut and Delaware Rivers, although the firs ...
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Antivenom
Antivenom, also known as antivenin, venom antiserum, and antivenom immunoglobulin, is a specific treatment for envenomation. It is composed of antibodies and used to treat certain venomous bites and stings. Antivenoms are recommended only if there is significant toxicity or a high risk of toxicity. The specific antivenom needed depends on the species involved. It is given by injection. Side effects may be severe. They include serum sickness, shortness of breath, and allergic reactions including anaphylaxis. Antivenom is traditionally made by collecting venom from the relevant animal and injecting small amounts of it into a domestic animal. The antibodies that form are then collected from the domestic animal's blood and purified. Versions are available for spider bites, snake bites, fish stings, and scorpion stings. Due to the high cost of producing antibody-based antivenoms and their short shelf lives when not refrigerated, alternative methods of production of antivenoms ar ...
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Toxicon
''Toxicon'' is a peer-reviewed scientific journal of toxinology and the official journal of the International Society on Toxinology and the North American Society of Toxinology. It is published by Elsevier and the editor-in-chief is Ray Norton. It aims to publish original research, novel findings, and review papers on toxins and their chemical, toxicological, pharmacological, and immunological properties. The journal was established in 1962. According to the ''Journal Citation Reports'', ''Toxicon'' has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 3.033. References External links * {{Official, http://www.elsevier.com/wps/find/journaldescription.cws_home/259/description Publications established in 1962 Elsevier academic journals English-languag ...
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LD-50
In toxicology, the median lethal dose, LD50 (abbreviation for "lethal dose, 50%"), LC50 (lethal concentration, 50%) or LCt50 is a toxic unit that measures the lethal dose of a toxin, radiation, or pathogen. The value of LD50 for a substance is the dose required to kill half the members of a tested population after a specified test duration. LD50 figures are frequently used as a general indicator of a substance's acute toxicity. A lower LD50 is indicative of increased toxicity. The test was created by J.W. Trevan in 1927. The term semilethal dose is occasionally used in the same sense, in particular with translations of foreign language text, but can also refer to a sublethal dose. LD50 is usually determined by tests on animals such as laboratory mice. In 2011, the U.S. Food and Drug Administration approved alternative methods to LD50 for testing the cosmetic drug Botox without animal tests. Conventions The LD50 is usually expressed as the mass of substance administered per unit ...
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Latrodectism
Latrodectism () is the illness caused by the bite of ''Latrodectus'' spiders (the black widow spider and related species). Pain, muscle rigidity, vomiting, and sweating are the symptoms of latrodectism. There are several spider species all named black widow: southern black widow spider (''L. mactans''), the European black widow (''L. tredecimguttatus''), Western black widow spider (''L. hesperus''), Northern black widow spider (''L. variolus''). Other ''Latrodectus'' that cause latrodectism are the Australian redback spider (''L. hasselti''), the New Zealand katipō spider (''L. katipo'') and the South American ''Latrodectus corallinus'' and ''Latrodectus curacaviensis''. Several other members of the genus ''Latrodectus'' are not commonly associated with latrodectism including the cosmopolitan brown widow (''L. geometricus''). Signs and symptoms Symptoms of a bite depend on the amount of venom injected. A bite of ''Latrodectus'' may not inject ...
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Quebec
Quebec ( ; )According to the Canadian government, ''Québec'' (with the acute accent) is the official name in Canadian French and ''Quebec'' (without the accent) is the province's official name in Canadian English is one of the thirteen provinces and territories of Canada. It is the largest province by area and the second-largest by population. Much of the population lives in urban areas along the St. Lawrence River, between the most populous city, Montreal, and the provincial capital, Quebec City. Quebec is the home of the Québécois nation. Located in Central Canada, the province shares land borders with Ontario to the west, Newfoundland and Labrador to the northeast, New Brunswick to the southeast, and a coastal border with Nunavut; in the south it borders Maine, New Hampshire, Vermont, and New York in the United States. Between 1534 and 1763, Quebec was called ''Canada'' and was the most developed colony in New France. Following the Seven Years' War, Quebec b ...
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Ontario
Ontario ( ; ) is one of the thirteen provinces and territories of Canada.Ontario is located in the geographic eastern half of Canada, but it has historically and politically been considered to be part of Central Canada. Located in Central Canada, it is Canada's most populous province, with 38.3 percent of the country's population, and is the second-largest province by total area (after Quebec). Ontario is Canada's fourth-largest jurisdiction in total area when the territories of the Northwest Territories and Nunavut are included. It is home to the nation's capital city, Ottawa, and the nation's most populous city, Toronto, which is Ontario's provincial capital. Ontario is bordered by the province of Manitoba to the west, Hudson Bay and James Bay to the north, and Quebec to the east and northeast, and to the south by the U.S. states of (from west to east) Minnesota, Michigan, Ohio, Pennsylvania, and New York. Almost all of Ontario's border with the United States f ...
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Massachusetts
Massachusetts (Massachusett language, Massachusett: ''Muhsachuweesut [Massachusett writing systems, məhswatʃəwiːsət],'' English: , ), officially the Commonwealth of Massachusetts, is the most populous U.S. state, state in the New England region of the Northeastern United States. It borders on the Atlantic Ocean and Gulf of Maine to the east, Connecticut and Rhode Island to the south, New Hampshire and Vermont to the north, and New York (state), New York to the west. The state's capital and List of municipalities in Massachusetts, most populous city, as well as its cultural and financial center, is Boston. Massachusetts is also home to the urban area, urban core of Greater Boston, the largest metropolitan area in New England and a region profoundly influential upon American History of the United States, history, academia, and the Economy of the United States, research economy. Originally dependent on agriculture, fishing, and trade. Massachusetts was transformed into a manuf ...
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Black Widow Spider
''Latrodectus'' is a broadly distributed genus of spiders with several species that are commonly known as the true widows. This group is composed of those often loosely called black widow spiders, brown widow spiders, and similar spiders. However, the diversity of species is much greater. A member of the family Theridiidae, this genus contains 34 species, which include several North American "black widows" (southern black widow ''Latrodectus mactans'', western black widow ''Latrodectus hesperus'', and northern black widow ''Latrodectus variolus''). Besides these, North America also has the red widow ''Latrodectus bishopi'' and the brown widow ''Latrodectus geometricus'', which, in addition to North America, has a much wider geographic distribution. Elsewhere, others include the European black widow (''Latrodectus tredecimguttatus''), the Australian redback black widow (''Latrodectus hasseltii'') and the closely related New Zealand katipō (''Latrodectus katipo''), several differ ...
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Maryland
Maryland ( ) is a state in the Mid-Atlantic region of the United States. It shares borders with Virginia, West Virginia, and the District of Columbia to its south and west; Pennsylvania to its north; and Delaware and the Atlantic Ocean to its east. Baltimore is the largest city in the state, and the capital is Annapolis. Among its occasional nicknames are '' Old Line State'', the ''Free State'', and the '' Chesapeake Bay State''. It is named after Henrietta Maria, the French-born queen of England, Scotland, and Ireland, who was known then in England as Mary. Before its coastline was explored by Europeans in the 16th century, Maryland was inhabited by several groups of Native Americans – mostly by Algonquian peoples and, to a lesser degree, Iroquoian and Siouan. As one of the original Thirteen Colonies of England, Maryland was founded by George Calvert, 1st Baron Baltimore, a Catholic convert"George Calvert and Cecilius Calvert, Barons Baltimore" William Hand Browne, ...
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Delaware
Delaware ( ) is a state in the Mid-Atlantic region of the United States, bordering Maryland to its south and west; Pennsylvania to its north; and New Jersey and the Atlantic Ocean to its east. The state takes its name from the adjacent Delaware Bay, in turn named after Thomas West, 3rd Baron De La Warr, an English nobleman and Virginia's first colonial governor. Delaware occupies the northeastern portion of the Delmarva Peninsula and some islands and territory within the Delaware River. It is the second-smallest and sixth-least populous state, but also the sixth-most densely populated. Delaware's largest city is Wilmington, while the state capital is Dover, the second-largest city in the state. The state is divided into three counties, having the lowest number of counties of any state; from north to south, they are New Castle County, Kent County, and Sussex County. While the southern two counties have historically been predominantly agricultural, New Castle is more ...
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