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EuroPhysiome
The physiome of an individual's or species' physiological state is the description of its functional behavior. The physiome describes the physiological dynamics of the normal intact organism and is built upon information and structure (genome, proteome, and morphome). The term comes from "physio-" (nature) and "-ome" (as a whole). The concept of a physiome project was presented to the International Union of Physiological Sciences (IUPS) by its Commission on Bioengineering in Physiology in 1993. A workshop on designing the Physiome Project was held in 1997. At its world congress in 2001, the IUPS designated the project as a major focus for the next decade. The project is led by the Physiome Commission of the IUPS. Other research initiatives related to the physiome include: *The EuroPhysiome Initiative *The NSR Physiome Project of the National Simulation Resource (NSR) at the University of Washington, supporting the IUPS Physiome Project *The Wellcome Trust Heart Physiome Project, a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Virtual Physiological Human
The Virtual Physiological Human (VPH) is a European initiative that focuses on a methodological and technological framework that, once established, will enable collaborative investigation of the human body as a single complex system. The collective framework will make it possible to share resources and observations formed by institutions and organizations, creating disparate but integrated computer models of the mechanical, physical and biochemical functions of a living human body. VPH is a framework which aims to be descriptive, integrative and predictive.STEP research road map Clapworthy ''et al.'' state that the framework should be descriptive by allowing laboratory and healthcare observations around the world "to be collected, catalogued, organized, shared and combined in any possible way." It shou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living Human Project
{{no footnotes, date=September 2016 The Living Human Project (LHP) is a project that begun in 2002 to develop a distributed repository of anatomo-functional data and simulation algorithms for the human musculoskeletal apparatus used to create the physiome of the human musculoskeletal system. In 2006 the BEL was merged with Biomed Town, an Internet community for those who have a professional interest in biomedical research. Living Human Digital Library The LHDL project was ended in January 2009, and soon after the LHDL consortium released a biomedical data management and sharing service called ''Physiome Space''. Physiome Space lets individual researchers as well as for large consortia to share with their peers large collections of biomedical data, including medical imaging and computer simulations. See also * List of omics topics in biology * Virtual Physiological Human * Physiomics * Physiome * Physiology * EuroPhysiome * Human anatomy The human body is the structure of a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Species
In biology, a species is the basic unit of classification and a taxonomic rank of an organism, as well as a unit of biodiversity. A species is often defined as the largest group of organisms in which any two individuals of the appropriate sexes or mating types can produce fertile offspring, typically by sexual reproduction. Other ways of defining species include their karyotype, DNA sequence, morphology, behaviour or ecological niche. In addition, paleontologists use the concept of the chronospecies since fossil reproduction cannot be examined. The most recent rigorous estimate for the total number of species of eukaryotes is between 8 and 8.7 million. However, only about 14% of these had been described by 2011. All species (except viruses) are given a two-part name, a "binomial". The first part of a binomial is the genus to which the species belongs. The second part is called the specific name or the specific epithet (in botanical nomenclature, also sometimes i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physiomics
Physiomics is a systematic study of physiome in biology. Physiomics employs bioinformatics to construct networks of physiological features that are associated with genes, proteins and their networks. A few of the methods for determining individual relationships between the DNA sequence and physiological function include metabolic pathway engineering and RNAi analysis. The relationships derived from methods such as these are organized and processed computationally to form distinct networks. Computer models use these experimentally determined networks to develop further predictions of gene function. History Physiomics arose from the imbalance between the amount of data being generated by genome projects and the technological ability to analyze the data on a large scale. As technologies such as high-throughput sequencing were being used to generate large amounts of genomic data, effective methods needed to be designed to experimentally interpret and computationally organize this dat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cardiophysics
Cardiophysics is an interdisciplinary science that stands at the junction of cardiology and medical physics, with researchers using the methods of, and theories from, physics to study cardiovascular system at different levels of its organisation, from the molecular scale to whole organisms. Being formed historically as part of systems biology, ''cardiophysics'' designed to reveal connections between the physical mechanisms, underlying the organization of the cardiovascular system, and biological features of its functioning. Zbigniew R. Struzik seems to be a first author who used the term in a scientific publication in 2004. One can use interchangeably also the terms ''cardiovascular physics''. See also * Medical physics * Important publications in medical physics * Biomedicine * Biomedical engineering * Physiome * Nanomedicine References * Books *# *# *# * Papers *# *# *# *# *# *# *# External links * Bioelectric Information Processing Laboratory of thInstit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Omics Topics In Biology
Inspired by the terms genome and genomics, other words to describe complete biological datasets, mostly sets of biomolecules originating from one organism, have been coined with the suffix '' -ome'' and ''-omics''. Some of these terms are related to each other in a hierarchical fashion. For example, the genome contains the ORFeome, which gives rise to the transcriptome, which is translated to the proteome. Other terms are overlapping and refer to the structure and/or function of a subset of proteins (e.g. glycome, kinome). An omicist is a scientist who studies omeomics, cataloging all the “omics” subfields. Omics.org is a Wiki that collects and alphabetically lists all the known "omes" and "omics." List of topics Hierarchy of topics For the sake of clarity, some topics are listed more than once. *Bibliome *Connectome *Cytome *Editome * Embryome *Epigenome **Methylome *Exposome ** Envirome *** Toxome ** Foodome **Microbiome ** Sociome *Genome **Variome **Exome ***ORFeome ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Genome Project
The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying, mapping and sequencing all of the genes of the human genome from both a physical and a functional standpoint. It started in 1990 and was completed in 2003. It remains the world's largest collaborative biological project. Planning started after the idea was picked up in 1984 by the US government, the project formally launched in 1990, and was declared essentially complete on April 14, 2003, but included only about 85% of the genome. Level "complete genome" was achieved in May 2021, with a remaining only 0.3% bases covered by potential issues. The final gapless assembly was finished in January 2022. Funding came from the United States government through the National Institutes of Health (NIH) as well as numerous other groups from around the world. A parallel project was conducted outside the government by the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cytome
Cytomics is the study of cell biology (cytology) and biochemistry in cellular systems at the single cell level. It combines all the bioinformatic knowledge to attempt to understand the molecular architecture and functionality of the cell system (Cytome). Much of this is achieved by using molecular and microscopic techniques that allow the various components of a cell to be visualised as they interact ''in vivo''. Cytome Cytomes are the cellular systems, subsystems, and functional components of the body. The cytome is the collection of the complex and dynamic cellular processes (structure and function) underlying physiological processes. It describes the structural and functional heterogeneity of the cellular diversity of an organism. Human Cytome Project The Human Cytome Project is aimed at the study of the biological system structure and function of an organism at the cytome level.Valet G., Predictive medicine by cytomics and the challenges of a human cytome project, Business Br ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Virtual Physiological Rat
The Virtual Physiological Rat (VPR) Project is an international collaboration aimed simulating the integrated cardiovascular function of the rat and supported by the National Institute of General Medical Sciences as a National Center for Systems Biology. The project is motivated by the fact that, although there exist both a depth of knowledge of basic cardiovascular physiology and a host of physiological and genomic data from animal models of disease, there is a lack of understanding of how multiple genes and environmental factors interact to determine cardiovascular phenotype. The Virtual Physiological Rat Project is focused on developing computational tools to capture the underlying systems physiology as well as the pathophysiological perturbations associated with disease. These tools are being developed and validated based on experimental characterization of physiological function across a number of organ systems in rat strains engineered to show relevant disease phenotypes. Compu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Oxford
, mottoeng = The Lord is my light , established = , endowment = £6.1 billion (including colleges) (2019) , budget = £2.145 billion (2019–20) , chancellor = The Lord Patten of Barnes , vice_chancellor = Louise Richardson , students = 24,515 (2019) , undergrad = 11,955 , postgrad = 12,010 , other = 541 (2017) , city = Oxford , country = England , coordinates = , campus_type = University town , athletics_affiliations = Blue (university sport) , logo_size = 250px , website = , logo = University of Oxford.svg , colours = Oxford Blue , faculty = 6,995 (2020) , academic_affiliations = , The University of Oxford is a collegiate research university in Oxf ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physiology
Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical and physical functions in a living system. According to the classes of organisms, the field can be divided into medical physiology, animal physiology, plant physiology, cell physiology, and comparative physiology. Central to physiological functioning are biophysical and biochemical processes, homeostatic control mechanisms, and communication between cells. ''Physiological state'' is the condition of normal function. In contrast, ''pathological state'' refers to abnormal conditions, including human diseases. The Nobel Prize in Physiology or Medicine is awarded by the Royal Swedish Academy of Sciences for exceptional scientific achievements in physiology related to the field of medicine. Foundations Cells Although there are differ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Auckland
, mottoeng = By natural ability and hard work , established = 1883; years ago , endowment = NZD $293 million (31 December 2021) , budget = NZD $1.281 billion (31 December 2021) , chancellor = Cecilia Tarrant , vice_chancellor = Dawn Freshwater , city = Auckland , country = New Zealand (Māori: ''Tāmaki Makaurau, Aotearoa'') , academic_staff = 2,402 (FTE, 2019) , administrative_staff = 3,567 (FTE, 2019) , students = 34,521 (EFTS, 2019) , undergrad = 25,200 (EFTS, 2019) , postgrad = 8,630 (EFTS, 2019) , type = Public flagship research university , campus = Urban,City Campus: 16 ha (40 acres)Total: 40 ha (99 acres) , free_label = Student Magazine , free = Craccum , colours = Auckland Dark Blue and White , affiliations = ACU, APAIE, APRU, Universitas 21, WUN , website Auckland.ac.nz, logo = File:University of Auckland.svg The University of Auckland is a public research university based in Auckland, New Zealand. It is the largest, most comprehen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
