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Erwin Friedrich Wagner
Erwin Friedrich Wagner (born 25 November 1950) is an Austrian biochemist known for his research on the molecular basis of cancer and associated conditions such as inflammation and cachexia. He was deputy director of the Spanish National Cancer Research Center (CNIO) in Madrid, Spain, until 2019. Since 2019, Wagner is a group leader affiliated with the Medical University of Vienna. Early life and education Erwin Wagner was born in Wolfsberg in the south of Austria. From 1974, he studied technical chemistry at the University of Graz, obtaining an engineering degree in 1974. In 1975, he worked in the lab of Fritz Paltauf on lipid chemistry. During his PhD studies, Erwin Wagner joined the Max Planck Institute for Molecular Genetics in Berlin with a Max Planck Fellowship for one year in 1976. He then joined the lab of Manfred Schweiger at the University of Innsbruck in 1977. Wagner obtained his PhD with a thesis on “Regulation of gene expression after virus infection” in 1978.< ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Friedrich Wagner
Friedrich E. Wagner (born November 16, 1943, sometimes abbreviated as Fritz Wagner) is a German physicist and emeritus professor who specializes in plasma physics. He was known to have discovered the high-confinement mode (i.e. H-mode) of magnetic confinement in fusion plasmas while working at the ASDEX tokamak in 1982. For this discovery and his subsequent contributions to fusion research, was awarded the John Dawson Award in 1987, the Hannes Alfvén Prize in 2007 and the Stern–Gerlach Medal in 2009. Life and career Wagner was born in Pfaffenhofen an der Roth in Bavaria, Germany. He studied at the Technical University of Munich and completed his doctorate in 1972. He then worked at Ohio State University from 1973 to 1974. At first, he worked on low-temperature physics, but switched to plasma fusion research during the energy crisis of the time. In 1975, he started working for the Max Planck Institute for Plasma Physics, and in 1986 he led the tokamak experiment ASDEX. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cachexia
Cachexia () is a complex syndrome associated with an underlying illness, causing ongoing muscle loss that is not entirely reversed with nutritional supplementation. A range of diseases can cause cachexia, most commonly cancer, congestive heart failure, chronic obstructive pulmonary disease, chronic kidney disease, and AIDS. Systemic inflammation from these conditions can cause detrimental changes to metabolism and body composition. In contrast to weight loss from inadequate caloric intake, cachexia causes mostly muscle loss instead of fat loss. Diagnosis of cachexia can be difficult due to the lack of well-established diagnostic criteria. Cachexia can improve with treatment of the underlying illness but other treatment approaches have limited benefit. Cachexia is associated with increased mortality and poor quality of life. The term is from Greek κακός ''kakos'', "bad", and ἕξις ''hexis'', "condition". Causes Cachexia can be caused by diverse medical conditions, but i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Developmental Cell
''Developmental Cell'' is a peer-reviewed scientific journal of cell and developmental biology. The journal was established in 2001, and is edited by Julie Sollier. It published by Cell Press, an imprint of Elsevier, and its articles becomes open access Open access (OA) is a set of principles and a range of practices through which research outputs are distributed online, free of access charges or other barriers. With open access strictly defined (according to the 2001 definition), or libre op ... after an embargo period of one year. External links * Cell Press academic journals Delayed open access journals Developmental biology journals Molecular and cellular biology journals Publications established in 2001 {{molec-cell-biology-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vienna
en, Viennese , iso_code = AT-9 , registration_plate = W , postal_code_type = Postal code , postal_code = , timezone = CET , utc_offset = +1 , timezone_DST = CEST , utc_offset_DST = +2 , blank_name = Vehicle registration , blank_info = W , blank1_name = GDP , blank1_info = € 96.5 billion (2020) , blank2_name = GDP per capita , blank2_info = € 50,400 (2020) , blank_name_sec1 = HDI (2019) , blank_info_sec1 = 0.947 · 1st of 9 , blank3_name = Seats in the Federal Council , blank3_info = , blank_name_sec2 = GeoTLD , blank_info_sec2 = .wien , website = , footnotes = , image_blank_emblem = Wien logo.svg , blank_emblem_size = Vienna ( ; german: Wien ; ba ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Germany
Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated between the Baltic and North seas to the north, and the Alps to the south; it covers an area of , with a population of almost 84 million within its 16 constituent states. Germany borders Denmark to the north, Poland and the Czech Republic to the east, Austria and Switzerland to the south, and France, Luxembourg, Belgium, and the Netherlands to the west. The nation's capital and most populous city is Berlin and its financial centre is Frankfurt; the largest urban area is the Ruhr. Various Germanic tribes have inhabited the northern parts of modern Germany since classical antiquity. A region named Germania was documented before AD 100. In 962, the Kingdom of Germany formed the bulk of the Holy Roman Empire. During the 16th ce ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heidelberg
Heidelberg (; Palatine German language, Palatine German: ''Heidlberg'') is a city in the States of Germany, German state of Baden-Württemberg, situated on the river Neckar in south-west Germany. As of the 2016 census, its population was 159,914, of which roughly a quarter consisted of students. Located about south of Frankfurt, Heidelberg is the List of cities in Baden-Württemberg by population, fifth-largest city in Baden-Württemberg. Heidelberg is part of the densely populated Rhine-Neckar, Rhine-Neckar Metropolitan Region. Heidelberg University, founded in 1386, is Germany's oldest and one of Europe's most reputable universities. Heidelberg is a Science, scientific hub in Germany and home to several internationally renowned #Research, research facilities adjacent to its university, including the European Molecular Biology Laboratory and four Max Planck Society, Max Planck Institutes. The city has also been a hub for the arts, especially literature, throughout the centurie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stem Cells
In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can differentiate into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they have slightly different properties in each. They are usually distinguished from progenitor cells, which cannot divide indefinitely, and precursor or blast cells, which are usually committed to differentiating into one cell type. In mammals, roughly 50–150 cells make up the inner cell mass during the blastocyst stage of embryonic development, around days 5–14. These have stem-cell capability. ''In vivo'', they eventually differentiate into all of the body's cell types (making them pluripotent). This process starts with the differentiation into the three germ layers – the ectoderm, mesoderm and endoderm – at the gastrulation stage. However, when ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Max Kade
Dr. h.c. Max Kade (13 October 1882, Steinbach near Schwäbisch Hall, Württemberg, Germany – 15 July 1967, Davos, Switzerland) was an emigrant from Germany to New York City who became successful in the pharmaceutical industry. Kade was committed to advancing German-American relations. He established a foundation in New York to promote scientific and technical progress and to further the peaceful coexistence of nations. Life Max Kade was born October 13, 1882, in Steinbach, a village near Schwäbisch Hall, Germany. His father was a partner in a machine factory and iron foundry. After finishing school, Kade completed a commercial apprenticeship in his father's business. Later he lived in Völklingen and Antwerp. In 1904 he emigrated to North America, living first in Montreal, then moving to New York in 1907. With a partner, he founded Seeck & Kade Inc., a pharmaceutical company, which after 1911 he directed alone. The company had great success with its cough syrup " Pertussin". On ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Beatrice Mintz
Beatrice Mintz (January 24, 1921 – January 3, 2022) was an American embryologist who contributed to the understanding of genetic modification, cellular differentiation, and cancer, particularly melanoma.Martha J. Bailey, ''American women in science: a biographical dictionary, Vol. 1'', ABC-CLIO, 1994, p. 252, Mintz was a pioneer of genetic engineering techniques and was among the first scientists to generate both chimeric and transgenic mammals. In 1996, she shared the inaugural March of Dimes Prize in Developmental Biology with Ralph L. Brinster for their work in developing transgenic mice. Much of her career was spent at Fox Chase Cancer Center in Philadelphia where, in 2002, she was appointed to the Jack Schultz Chair in Basic Science.Alumni Fellows, 2002 Recipients , The University of Iowa Mintz ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States
The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territories, nine Minor Outlying Islands, and 326 Indian reservations. The United States is also in free association with three Pacific Island sovereign states: the Federated States of Micronesia, the Marshall Islands, and the Republic of Palau. It is the world's third-largest country by both land and total area. It shares land borders with Canada to its north and with Mexico to its south and has maritime borders with the Bahamas, Cuba, Russia, and other nations. With a population of over 333 million, it is the most populous country in the Americas and the third most populous in the world. The national capital of the United States is Washington, D.C. and its most populous city and principal financial center is New York City. Paleo-Americ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Philadelphia
Philadelphia, often called Philly, is the largest city in the Commonwealth of Pennsylvania, the sixth-largest city in the U.S., the second-largest city in both the Northeast megalopolis and Mid-Atlantic regions after New York City. Since 1854, the city has been coextensive with Philadelphia County, the most populous county in Pennsylvania and the urban core of the Delaware Valley, the nation's seventh-largest and one of world's largest metropolitan regions, with 6.245 million residents . The city's population at the 2020 census was 1,603,797, and over 56 million people live within of Philadelphia. Philadelphia was founded in 1682 by William Penn, an English Quaker. The city served as capital of the Pennsylvania Colony during the British colonial era and went on to play a historic and vital role as the central meeting place for the nation's founding fathers whose plans and actions in Philadelphia ultimately inspired the American Revolution and the nation's inde ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
