|
Denise P. Barlow
Denise P. Barlow (31 January 1950 – 21 October 2017) was a British geneticist who worked in the field of epigenomics. Barlow was an elected member of European Molecular Biology Organization (EMBO), an honorary professor of genetics at the University of Vienna and recipient of the Erwin Schrödinger Prize of the Austrian Academy of Sciences. In 1991, she discovered the first mammalian imprinted gene, IGF2R, which codes for the insulin-like growth factor. Biography Early years Denise Barlow was born in Yorkshire, UK on 31 January 1950. When she was 16, she started a two-year pre-nursing course at a technical college. At the age of 18, she trained and worked for four years as a state registered nurse (SRN) in the United Kingdom. During this time, she decided to enroll at a university to learn more about human physiology and diseases, but had to attend another technical college to take A-levels first. Research work At the age of 25, Barlow started to study at the University of R ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yorkshire
Yorkshire ( ; abbreviated Yorks), formally known as the County of York, is a Historic counties of England, historic county in northern England and by far the largest in the United Kingdom. Because of its large area in comparison with other English counties, functions have been undertaken over time by its subdivisions, which have also been subject to History of local government in Yorkshire, periodic reform. Throughout these changes, Yorkshire has continued to be recognised as a geographic territory and cultural region. The name is familiar and well understood across the United Kingdom and is in common use in the media and the Yorkshire Regiment, military, and also features in the titles of current areas of civil administration such as North Yorkshire, South Yorkshire, West Yorkshire and the East Riding of Yorkshire. Within the borders of the historic county of Yorkshire are large stretches of countryside, including the Yorkshire Dales, North York Moors and Peak District nationa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Insulin-like Growth Factor
The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin. IGFs are part of a complex system that cells use to communicate with their physiologic environment. This complex system (often referred to as the IGF "axis") consists of two cell-surface receptors (IGF1R and IGF2R), two ligands (IGF-1 and IGF-2), a family of seven high-affinity IGF-binding proteins (IGFBP1 to IGFBP7), as well as associated IGFBP degrading enzymes, referred to collectively as proteases. IGF1/GH axis The IGF "axis" is also commonly referred to as the Growth Hormone/IGF-1 Axis. Insulin-like growth factor 1 (commonly referred to as IGF-1 or at times using Roman numerals as IGF-I) is mainly secreted by the liver as a result of stimulation by growth hormone (GH). IGF-1 is important for both the regulation of normal physiology, as well as a number of pathological states, including cancer. The IGF axis has been shown to play roles in the promotion of cell proliferation and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brigid Hogan
Brigid L. M. Hogan FRS is a developmental biologist noted for her contributions to mammalian development, stem cell research and transgenic technology and techniques. She is currently a Professor in the Department of Cell Biology at Duke University,http://www.cellbio.duke.edu/brigid-l-m-hogan/ Duke University Faculty Page Born in the UK, she became an American citizen in 2000. Hogan earned her PhD in Biochemistry at the University of Cambridge and did postdoctoral work in the Department of Biology at MIT. She was the head of the Laboratory of Molecular Embryology at the National Institute for Medical Research in London, and later Hortense B. Ingram Professor in the Department of Cell Biology and a founding director of the Stem Cell and Organogenesis Program at Vanderbilt University. [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Interferon
Interferons (IFNs, ) are a group of signaling proteins made and released by host cells in response to the presence of several viruses. In a typical scenario, a virus-infected cell will release interferons causing nearby cells to heighten their anti-viral defenses. IFNs belong to the large class of proteins known as cytokines, molecules used for communication between cells to trigger the protective defenses of the immune system that help eradicate pathogens. Interferons are named for their ability to "interfere" with viral replication by protecting cells from virus infections. However, virus-encoded genetic elements have the ability to antagonize the IFN response contributing to viral pathogenesis and viral diseases. IFNs also have various other functions: they activate immune cells, such as natural killer cells and macrophages, and they increase host defenses by up-regulating antigen presentation by virtue of increasing the expression of major histocompatibility complex (M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Derek Burke
Derek Clissold Burke (13 February 1930 – 15 March 2019) was a British academic who served as Vice-Chancellor of the University of East Anglia from 1987 to 1995. He was educated at Bishop Vesey's Grammar School and at the University of Birmingham (BSc, PhD). He began his career as a research fellow in chemistry at Yale, before becoming a lecturer in biological chemistry at the University of Aberdeen. He then served as Professor of Biological Sciences at the University of Warwick from 1969 to 1982, and Eleanor Roosevelt fellow at the University of Colorado from 1975 to 1976. He was appointed Vice-Chancellor of the University of East Anglia in 1987 and held the post until 1995. He was appointed a CBE in 1994 and is a deputy lieutenant of Norfolk. He lived in Cringleford. He was an Honorary Fellow of St Edmund's College, Cambridge St Edmund's College is a constituent college of the University of Cambridge in England. Founded in 1896, it is the second-oldest of the four Cambri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Doctor Of Philosophy
A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common Academic degree, degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields. Because it is an earned research degree, those studying for a PhD are required to produce original research that expands the boundaries of knowledge, normally in the form of a Thesis, dissertation, and defend their work before a panel of other experts in the field. The completion of a PhD is often a requirement for employment as a university professor, researcher, or scientist in many fields. Individuals who have earned a Doctor of Philosophy degree may, in many jurisdictions, use the title ''Doctor (title), Doctor'' (often abbreviated "Dr" or "Dr.") with their name, although the proper etiquette associated with this usage may also be subject to the professional ethics of their own scholarly field, culture, or society. Those who teach at ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biochemistry
Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all areas of the life sciences are being uncovered and developed through biochemical methodology and research. Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis which allows biological molecules to give rise to the processes that occur within living cells and between cells,Karp (2009), p. 2. in turn relating greatly to the understanding of tissues and organs, as well as organism structure and function.Miller (2012). p. 62. Biochemistry is closely related to molecular biology, which is the study of the molecular mechanisms of biological phenomena.As ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Zoology
Zoology ()The pronunciation of zoology as is usually regarded as nonstandard, though it is not uncommon. is the branch of biology that studies the Animal, animal kingdom, including the anatomy, structure, embryology, evolution, Biological classification, classification, Ethology, habits, and distribution of all animals, both living and extinction, extinct, and how they interact with their ecosystems. The term is derived from Ancient Greek , ('animal'), and , ('knowledge', 'study'). Although humans have always been interested in the natural history of the animals they saw around them, and made use of this knowledge to domesticate certain species, the formal study of zoology can be said to have originated with Aristotle. He viewed animals as living organisms, studied their structure and development, and considered their adaptations to their surroundings and the function of their parts. The Greek physician Galen studied human anatomy and was one of the greatest surgeons of the a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bachelor Of Science
A Bachelor of Science (BS, BSc, SB, or ScB; from the Latin ') is a bachelor's degree awarded for programs that generally last three to five years. The first university to admit a student to the degree of Bachelor of Science was the University of London in 1860. In the United States, the Lawrence Scientific School first conferred the degree in 1851, followed by the University of Michigan in 1855. Nathaniel Southgate Shaler, who was Harvard's Dean of Sciences, wrote in a private letter that "the degree of Bachelor of Science came to be introduced into our system through the influence of Louis Agassiz, who had much to do in shaping the plans of this School." Whether Bachelor of Science or Bachelor of Arts degrees are awarded in particular subjects varies between universities. For example, an economics student may graduate as a Bachelor of Arts in one university but as a Bachelor of Science in another, and occasionally, both options are offered. Some universities follow the Oxford a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Reading
The University of Reading is a public university in Reading, Berkshire, England. It was founded in 1892 as University College, Reading, a University of Oxford extension college. The institution received the power to grant its own degrees in 1926 by royal charter from King George V and was the only university to receive such a charter between the two world wars. The university is usually categorised as a red brick university, reflecting its original foundation in the 19th century. Reading has four major campuses. In the United Kingdom, the campuses on London Road and Whiteknights are based in the town of Reading itself, and Greenlands is based on the banks of the River Thames in Buckinghamshire. It also has a campus in Iskandar Puteri, Malaysia. The university has been arranged into 16 academic schools since 2016. The annual income of the institution for 2016–17 was £275.3 million of which £35.4 million was from research grants and contracts, with an expenditur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
GCE Advanced Level
The A-Level (Advanced Level) is a subject-based qualification conferred as part of the General Certificate of Education, as well as a school leaving qualification offered by the educational bodies in the United Kingdom and the educational authorities of British Crown dependencies to students completing secondary or pre-university education. They were introduced in England and Wales in 1951 to replace the Higher School Certificate. A number of Commonwealth countries have developed qualifications with the same name as and a similar format to the British A Levels. Obtaining an A Level, or equivalent qualifications, is generally required across the board for university entrance, with universities granting offers based on grades achieved. Particularly in Singapore, its A level examinations have been regarded as being much more challenging than the United Kingdom, with most universities offering lower entry qualifications with regard to grades achieved on a Singaporean A level ce ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physiology
Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical and physical functions in a living system. According to the classes of organisms, the field can be divided into medical physiology, animal physiology, plant physiology, cell physiology, and comparative physiology. Central to physiological functioning are biophysical and biochemical processes, homeostatic control mechanisms, and communication between cells. ''Physiological state'' is the condition of normal function. In contrast, ''pathological state'' refers to abnormal conditions, including human diseases. The Nobel Prize in Physiology or Medicine is awarded by the Royal Swedish Academy of Sciences for exceptional scientific achievements in physiology related to the field of medicine. Foundations Cells Although there are differ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
_(2).JPG "Click for more on -> GCE Advanced Level")