Nanotechnology, also shortened to nanotech, is the use of matter on an atom
, and supramolecular
scale for industrial purposes. The earliest, widespread description of nanotechnology referred to the particular technological goal of precisely manipulating atoms and molecules for fabrication of macroscale products, also now referred to as molecular nanotechnology
A more generalized description of nanotechnology was subsequently established by the National Nanotechnology Initiative
, which defined nanotechnology as the manipulation of matter with at least one dimension sized from 1
to 100 nanometers
. This definition reflects the fact that quantum mechanical
effects are important at this quantum-realm
scale, and so the definition shifted from a particular technological goal to a research category inclusive of all types of research and technologies that deal with the special properties of matter which occur below the given size threshold. It is therefore common to see the plural form "nanotechnologies" as well as "nanoscale technologies" to refer to the broad range of research and applications whose common trait is size.
Nanotechnology as defined by size is naturally broad, including fields of science as diverse as surface science
, organic chemistry
, molecular biology
, semiconductor physics
, energy storage
, and molecular engineering
. The associated research and applications are equally diverse, ranging from extensions of conventional device physics
to completely new approaches based upon molecular self-assembly
, from developing new materials
with dimensions on the nanoscale to direct control of matter on the atomic scale
Scientists currently debate the future implications of nanotechnology
. Nanotechnology may be able to create many new materials and devices with a vast range of applications
, such as in nanomedicine
s energy production, and consumer products. On the other hand, nanotechnology raises many of the same issues as any new technology, including concerns about the toxicity
and environmental impact of nanomaterials, and their potential effects on global economics, as well as speculation about various doomsday scenarios
. These concerns have led to a debate among advocacy groups and governments on whether special regulation of nanotechnology
The concepts that seeded nanotechnology were first discussed in 1959 by renowned physicist Richard Feynman
in his talk ''There's Plenty of Room at the Bottom
'', in which he described the possibility of synthesis via direct manipulation of atoms.
The term "nano-technology" was first used by Norio Taniguchi
in 1974, though it was not widely known. Inspired by Feynman's concepts, K. Eric Drexler
used the term "nanotechnology" in his 1986 book ''Engines of Creation: The Coming Era of Nanotechnology
'', which proposed the idea of a nanoscale "assembler" which would be able to build a copy of itself and of other items of arbitrary complexity with atomic control. Also in 1986, Drexler co-founded The Foresight Institute
(with which he is no longer affiliated) to help increase public awareness and understanding of nanotechnology concepts and implications.
The emergence of nanotechnology as a field in the 1980s occurred through convergence of Drexler's theoretical and public work, which developed and popularized a conceptual framework for nanotechnology, and high-visibility experimental advances that drew additional wide-scale attention to the prospects of atomic control of matter. In the 1980s, two major breakthroughs sparked the growth of nanotechnology in modern era. First, the invention of the scanning tunneling microscope
in 1981 which provided unprecedented visualization of individual atoms and bonds, and was successfully used to manipulate individual atoms in 1989. The microscope's developers Gerd Binnig
and Heinrich Rohrer
at IBM Zurich Research Laboratory
received a Nobel Prize in Physics
and Gerber also invented the analogous atomic force microscope
were discovered in 1985 by Harry Kroto
, Richard Smalley
, and Robert Curl
, who together won the 1996 Nobel Prize in Chemistry
was not initially described as nanotechnology; the term was used regarding subsequent work with related graphene
tubes (called carbon nanotube
s and sometimes called Bucky tubes) which suggested potential applications for nanoscale electronics and devices. The discovery of carbon nanotubes
is largely attributed to Sumio Iijima
for which Iijima won the inaugural 2008 Kavli Prize
A nanolayer-base metal–semiconductor junction
(M–S junction) transistor
was initially proposed by A. Rose in 1960, and fabricated
by L. Geppert, Mohamed Atalla
and Dawon Kahng
in 1962. Decades later, advances in multi-gate
technology enabled the scaling
of metal–oxide–semiconductor field-effect transistor
(MOSFET) devices down to nano-scale
levels smaller than 20 nm
gate length, starting with the FinFET
(fin field-effect transistor), a three-dimensional, non-planar, double-gate MOSFET. At UC Berkeley
, a team of researchers including Digh Hisamoto, Chenming Hu
, Tsu-Jae King Liu
, Jeffrey Bokor and others fabricated FinFET devices down to a 17nm
process in 1998, then 15nm
in 2001, and then 10nm
In the early 2000s, the field garnered increased scientific, political, and commercial attention that led to both controversy and progress. Controversies emerged regarding the definitions and potential implications of nanotechnologies, exemplified by the Royal Society
's report on nanotechnology.
Challenges were raised regarding the feasibility of applications envisioned by advocates of molecular nanotechnology, which culminated in a public debate between Drexler and Smalley in 2001 and 2003.
Meanwhile, commercialization of products based on advancements in nanoscale technologies began emerging. These products are limited to bulk applications of nanomaterials
and do not involve atomic control of matter. Some examples include the Silver Nano
platform for using silver nanoparticles
as an antibacterial agent, nanoparticle
-based transparent sunscreens, carbon fiber
strengthening using silica nanoparticles, and carbon nanotubes for stain-resistant textiles.
Governments moved to promote and fund research
into nanotechnology, such as in the U.S. with the National Nanotechnology Initiative
, which formalized a size-based definition of nanotechnology and established funding for research on the nanoscale, and in Europe via the European Framework Programmes for Research and Technological Development
By the mid-2000s new and serious scientific attention began to flourish. Projects emerged to produce nanotechnology roadmaps
which center on atomically precise manipulation of matter and discuss existing and projected capabilities, goals, and applications.
In 2006, a team of Korean researchers from the Korea Advanced Institute of Science and Technology
(KAIST) and the National Nano Fab Center developed a 3 nm
MOSFET, the world's smallest nanoelectronic
device. It was based on gate-all-around
(GAA) FinFET technology.
Over sixty countries created nanotechnology research and development
(R&D) government programs between 2001 and 2004. Government funding was exceeded by corporate spending on nanotechnology R&D, with most of the funding coming from corporations based in the United States, Japan and Germany. The top five organizations that filed the most intellectual patent
s on nanotechnology R&D between 1970 and 2011 were Samsung Electronics
(2,578 first patents), Nippon Steel
(1,490 first patents), IBM
(1,360 first patents), Toshiba
(1,298 first patents) and Canon
(1,162 first patents). The top five organizations that published the most scientific papers on nanotechnology research between 1970 and 2012 were the Chinese Academy of Sciences
, Russian Academy of Sciences
, Centre national de la recherche scientifique
, University of Tokyo
and Osaka University
Nanotechnology is the engineering of functional systems at the molecular scale. This covers both current work and concepts that are more advanced. In its original sense, nanotechnology refers to the projected ability to construct items from the bottom up, using techniques and tools being developed today to make complete, high performance products.
(nm) is one billionth, or 10−9
, of a meter. By comparison, typical carbon-carbon bond length
s, or the spacing between these atom
s in a molecule
, are in the range , and a DNA
double-helix has a diameter around 2 nm. On the other hand, the smallest cellular
life-forms, the bacteria of the genus ''Mycoplasma
'', are around 200 nm in length. By convention, nanotechnology is taken as the scale range following the definition used by the National Nanotechnology Initiative in the US. The lower limit is set by the size of atoms (hydrogen has the smallest atoms, which are approximately a quarter of a nm kinetic diameter
) since nanotechnology must build its devices from atoms and molecules. The upper limit is more or less arbitrary but is around the size below which phenomena not observed in larger structures start to become apparent and can be made use of in the nano device. These new phenomena make nanotechnology distinct from devices which are merely miniaturised versions of an equivalent macroscopic
device; such devices are on a larger scale and come under the description of microtechnology
To put that scale in another context, the comparative size of a nanometer to a meter is the same as that of a marble to the size of the earth.
Or another way of putting it: a nanometer is the amount an average man's beard grows in the time it takes him to raise the razor to his face.
Two main approaches are used in nanotechnology. In the "bottom-up" approach, materials and devices are built from molecular components which assemble themselves
chemically by principles of molecular recognition
In the "top-down" approach, nano-objects are constructed from larger entities without atomic-level control.
Areas of physics such as nanoelectronics
have evolved during the last few decades to provide a basic scientific foundation of nanotechnology.
Larger to smaller: a materials perspective
Several phenomena become pronounced as the size of the system decreases. These include statistical mechanical
effects, as well as quantum mechanical
effects, for example the "quantum
size effect" where the electronic properties of solids are altered with great reductions in particle size. This effect does not come into play by going from macro to micro dimensions. However, quantum effects can become significant when the nanometer size range is reached, typically at distances of 100 nanometers or less, the so-called quantum realm
. Additionally, a number of physical (mechanical, electrical, optical, etc.) properties change when compared to macroscopic systems. One example is the increase in surface area to volume ratio altering mechanical, thermal and catalytic properties of materials. Diffusion and reactions at nanoscale, nanostructures materials and nanodevices with fast ion transport are generally referred to nanoionics. ''Mechanical'' properties of nanosystems are of interest in the nanomechanics research. The catalytic activity of nanomaterials also opens potential risks in their interaction with biomaterial
Materials reduced to the nanoscale can show different properties compared to what they exhibit on a macroscale, enabling unique applications. For instance, opaque substances can become transparent (copper); stable materials can turn combustible (aluminium); insoluble materials may become soluble (gold). A material such as gold, which is chemically inert at normal scales, can serve as a potent chemical catalyst
at nanoscales. Much of the fascination with nanotechnology stems from these quantum and surface phenomena that matter exhibits at the nanoscale.
Simple to complex: a molecular perspective
Modern synthetic chemistry
has reached the point where it is possible to prepare small molecules to almost any structure. These methods are used today to manufacture a wide variety of useful chemicals such as pharmaceuticals
or commercial polymer
s. This ability raises the question of extending this kind of control to the next-larger level, seeking methods to assemble these single molecules into supramolecular assemblies
consisting of many molecules arranged in a well defined manner.
These approaches utilize the concepts of molecular self-assembly and/or supramolecular chemistry
to automatically arrange themselves into some useful conformation through a bottom-up
approach. The concept of molecular recognition is especially important: molecules can be designed so that a specific configuration or arrangement is favored due to non-covalent intermolecular force
s. The Watson–Crick basepairing
rules are a direct result of this, as is the specificity of an enzyme
being targeted to a single substrate
, or the specific folding of the protein
itself. Thus, two or more components can be designed to be complementary and mutually attractive so that they make a more complex and useful whole.
Such bottom-up approaches should be capable of producing devices in parallel and be much cheaper than top-down methods, but could potentially be overwhelmed as the size and complexity of the desired assembly increases. Most useful structures require complex and thermodynamically unlikely arrangements of atoms. Nevertheless, there are many examples of self-assembly based on molecular recognition in biology
, most notably Watson–Crick basepairing and enzyme-substrate interactions. The challenge for nanotechnology is whether these principles can be used to engineer new constructs in addition to natural ones.
Molecular nanotechnology: a long-term view
Molecular nanotechnology, sometimes called molecular manufacturing, describes engineered nanosystems (nanoscale machines) operating on the molecular scale. Molecular nanotechnology is especially associated with the molecular assembler
, a machine that can produce a desired structure or device atom-by-atom using the principles of mechanosynthesis
. Manufacturing in the context of productive nanosystems
is not related to, and should be clearly distinguished from, the conventional technologies used to manufacture nanomaterials such as carbon nanotubes and nanoparticles.
When the term "nanotechnology" was independently coined and popularized by Eric Drexler
(who at the time was unaware of an earlier usage
by Norio Taniguchi) it referred to a future manufacturing technology based on molecular machine
systems. The premise was that molecular scale biological analogies of traditional machine components demonstrated molecular machines were possible: by the countless examples found in biology, it is known that sophisticated, stochastic
ally optimised biological machines
can be produced.
It is hoped that developments in nanotechnology will make possible their construction by some other means, perhaps using biomimetic
principles. However, Drexler and other researchers have proposed that advanced nanotechnology, although perhaps initially implemented by biomimetic means, ultimately could be based on mechanical engineering principles, namely, a manufacturing technology based on the mechanical functionality of these components (such as gears, bearings, motors, and structural members) that would enable programmable, positional assembly to atomic specification. The physics and engineering performance of exemplar designs were analyzed in Drexler's book ''Nanosystems''.
In general it is very difficult to assemble devices on the atomic scale, as one has to position atoms on other atoms of comparable size and stickiness. Another view, put forth by Carlo Montemagno
, is that future nanosystems will be hybrids of silicon technology and biological molecular machines. Richard Smalley argued that mechanosynthesis are impossible due to the difficulties in mechanically manipulating individual molecules.
This led to an exchange of letters in the ACS
publication Chemical & Engineering News
in 2003. Though biology clearly demonstrates that molecular machine systems are possible, non-biological molecular machines are today only in their infancy. Leaders in research on non-biological molecular machines are Dr. Alex Zettl
and his colleagues at Lawrence Berkeley Laboratories and UC Berkele
They have constructed at least three distinct molecular devices whose motion is controlled from the desktop with changing voltage: a nanotube nanomotor
, a molecular actuator, and a nanoelectromechanical relaxation oscillator. See nanotube nanomotor
for more examples.
An experiment indicating that positional molecular assembly is possible was performed by Ho and Lee at Cornell University
in 1999. They used a scanning tunneling microscope to move an individual carbon monoxide molecule (CO) to an individual iron atom (Fe) sitting on a flat silver crystal, and chemically bound the CO to the Fe by applying a voltage.
s to nanocrystal
s above them, causing the nanocrystals to emit visible light.]]
The nanomaterials field includes subfields which develop or study materials having unique properties arising from their nanoscale dimensions.
*Interface and colloid science
has given rise to many materials which may be useful in nanotechnology, such as carbon nanotubes and other fullerenes, and various nanoparticles and nanorod
s. Nanomaterials with fast ion transport are related also to nanoionics and nanoelectronics.
*Nanoscale materials can also be used for bulk applications; most present commercial applications of nanotechnology are of this flavor.
*Progress has been made in using these materials for medical applications; see Nanomedicine
*Nanoscale materials such as nanopillar
s are sometimes used in solar cell
s which combats the cost of traditional silicon
*Development of applications incorporating semiconductor nanoparticle
s to be used in the next generation of products, such as display technology, lighting, solar cells and biological imaging; see quantum dots
*Recent application of nanomaterials
include a range of biomedical
applications, such as tissue engineering
, drug delivery
These seek to arrange smaller components into more complex assemblies.
*DNA nanotechnology utilizes the specificity of Watson–Crick basepairing to construct well-defined structures out of DNA and other nucleic acid
*Approaches from the field of "classical" chemical synthesis (Inorganic and organic synthesis
) also aim at designing molecules with well-defined shape (e.g. bis-peptide
*More generally, molecular self-assembly seeks to use concepts of supramolecular chemistry, and molecular recognition in particular, to cause single-molecule components to automatically arrange themselves into some useful conformation.
*Atomic force microscope
tips can be used as a nanoscale "write head" to deposit a chemical upon a surface in a desired pattern in a process called dip pen nanolithography
. This technique fits into the larger subfield of nanolithography
*Molecular Beam Epitaxy
allows for bottom up assemblies of materials, most notably semiconductor materials commonly used in chip and computing applications, stacks, gating, and nanowire lasers
These seek to create smaller devices by using larger ones to direct their assembly.
*Many technologies that descended from conventional solid-state silicon methods
for fabricating microprocessor
s are now capable of creating features smaller than 100 nm, falling under the definition of nanotechnology. Giant magnetoresistance
-based hard drives already on the market fit this description, as do atomic layer deposition
(ALD) techniques. Peter Grünberg
and Albert Fert
received the Nobel Prize in Physics in 2007 for their discovery of Giant magnetoresistance and contributions to the field of spintronics.
*Solid-state techniques can also be used to create devices known as nanoelectromechanical systems
or NEMS, which are related to microelectromechanical systems
*Focused ion beam
s can directly remove material, or even deposit material when suitable precursor gasses are applied at the same time. For example, this technique is used routinely to create sub-100 nm sections of material for analysis in Transmission electron microscopy
*Atomic force microscope tips can be used as a nanoscale "write head" to deposit a resist, which is then followed by an etching process to remove material in a top-down method.
These seek to develop components of a desired functionality without regard to how they might be assembled.
*Magnetic assembly for the synthesis of anisotropic superparamagnetic materials such as recently presented magnetic nano chains
*Molecular scale electronics
seeks to develop molecules with useful electronic properties. These could then be used as single-molecule components in a nanoelectronic device. For an example see rotaxane.
*Synthetic chemical methods can also be used to create synthetic molecular motor
s, such as in a so-called nanocar
seeks to apply biological methods and systems found in nature, to the study and design of engineering systems and modern technology. Biomineralization
is one example of the systems studied.
is the use of biomolecule
s for applications in nanotechnology, including use of viruses and lipid assemblies. Nanocellulose
is a potential bulk-scale application.
These subfields seek to anticipate
what inventions nanotechnology might yield, or attempt to propose an agenda along which inquiry might progress. These often take a big-picture view of nanotechnology, with more emphasis on its societal implications than the details of how such inventions could actually be created.
*Molecular nanotechnology is a proposed approach which involves manipulating single molecules in finely controlled, deterministic ways. This is more theoretical than the other subfields, and many of its proposed techniques are beyond current capabilities.
centers on self-sufficient machines of some functionality operating at the nanoscale. There are hopes for applying nanorobots in medicine. Nevertheless, progress on innovative materials and methodologies has been demonstrated with some patents granted about new nanomanufacturing devices for future commercial applications, which also progressively helps in the development towards nanorobots with the use of embedded nanobioelectronics concepts.
*Productive nanosystems are "systems of nanosystems" which will be complex nanosystems that produce atomically precise parts for other nanosystems, not necessarily using novel nanoscale-emergent properties, but well-understood fundamentals of manufacturing. Because of the discrete (i.e. atomic) nature of matter and the possibility of exponential growth, this stage is seen as the basis of another industrial revolution. Mihail Roco
, one of the architects of the USA's National Nanotechnology Initiative, has proposed four states of nanotechnology that seem to parallel the technical progress of the Industrial Revolution, progressing from passive nanostructures to active nanodevices to complex nanomachine
s and ultimately to productive nanosystems.
seeks to design materials whose properties can be easily, reversibly and externally controlled though a fusion of information science
and materials science
*Due to the popularity and media exposure of the term nanotechnology, the words picotechnology
have been coined in analogy to it, although these are only used rarely and informally.
Dimensionality in nanomaterials
Nanomaterials can be classified in 0D, 1D, 2D and 3D nanomaterials
. The dimensionality play a major role in determining the characteristic of nanomaterials including physical
characteristics. With the decrease in dimensionality, an increase in surface-to-volume ratio is observed. This indicate that smaller dimensional nanomaterials
have higher surface area compared to 3D nanomaterials. Recently, two dimensional (2D) nanomaterials
are extensively investigated for electronic
, drug delivery
Tools and techniques
There are several important modern developments. The atomic force microscope
(AFM) and the Scanning Tunneling Microscope
(STM) are two early versions of scanning probes that launched nanotechnology. There are other types of scanning probe microscopy
. Although conceptually similar to the scanning confocal microscope
developed by Marvin Minsky
in 1961 and the scanning acoustic microscope
(SAM) developed by Calvin Quate
and coworkers in the 1970s, newer scanning probe microscopes have much higher resolution, since they are not limited by the wavelength of sound or light.
The tip of a scanning probe can also be used to manipulate nanostructures (a process called positional assembly). Feature-oriented scanning
methodology may be a promising way to implement these nanomanipulations in automatic mode.
However, this is still a slow process because of low scanning velocity of the microscope.
Various techniques of nanolithography such as optical lithography
, X-ray lithography
, dip pen nanolithography, electron beam lithography
or nanoimprint lithography
were also developed. Lithography is a top-down fabrication technique where a bulk material is reduced in size to nanoscale pattern.
Another group of nanotechnological techniques include those used for fabrication of nanotubes
, those used in semiconductor fabrication such as deep ultraviolet lithography, electron beam lithography, focused ion beam machining, nanoimprint lithography, atomic layer deposition, and molecular vapor deposition, and further including molecular self-assembly techniques such as those employing di-block copolymers. The precursors of these techniques preceded the nanotech era, and are extensions in the development of scientific advancements rather than techniques which were devised with the sole purpose of creating nanotechnology and which were results of nanotechnology research.
The top-down approach anticipates nanodevices that must be built piece by piece in stages, much as manufactured items are made. Scanning probe microscopy is an important technique both for characterization and synthesis of nanomaterials. Atomic force microscopes and scanning tunneling microscopes can be used to look at surfaces and to move atoms around. By designing different tips for these microscopes, they can be used for carving out structures on surfaces and to help guide self-assembling structures. By using, for example, feature-oriented scanning approach, atoms or molecules can be moved around on a surface with scanning probe microscopy techniques.
At present, it is expensive and time-consuming for mass production but very suitable for laboratory experimentation.
In contrast, bottom-up techniques build or grow larger structures atom by atom or molecule by molecule. These techniques include chemical synthesis, self-assembly
and positional assembly. Dual polarisation interferometry
is one tool suitable for characterisation of self assembled thin films. Another variation of the bottom-up approach is molecular beam epitaxy
or MBE. Researchers at Bell Telephone Laboratories
like John R. Arthur. Alfred Y. Cho, and Art C. Gossard developed and implemented MBE as a research tool in the late 1960s and 1970s. Samples made by MBE were key to the discovery of the fractional quantum Hall effect for which the 1998 Nobel Prize in Physics was awarded. MBE allows scientists to lay down atomically precise layers of atoms and, in the process, build up complex structures. Important for research on semiconductors, MBE is also widely used to make samples and devices for the newly emerging field of spintronics
However, new therapeutic products, based on responsive nanomaterials, such as the ultradeformable, stress-sensitive Transfersome
vesicles, are under development and already approved for human use in some countries.
Research and development
Because of the variety of potential applications (including industrial and military), governments have invested billions of dollars in nanotechnology research. Prior to 2012, the USA invested $3.7 billion using its National Nanotechnology Initiative
, the European Union invested $1.2 billion, and Japan invested $750 million. Over sixty countries created nanotechnology research and development
(R&D) programs between 2001 and 2004. In 2012, the US and EU each invested on nanotechnology research, followed by Japan with . Global investment reached in 2012. Government funding was exceeded by corporate R&D spending on nanotechnology research, which was in 2012. The largest corporate R&D spenders were from the US, Japan and Germany which accounted for a combined .
thumb|Nanostructures provide this surface with superhydrophobicity
, which lets [[water droplets roll down the [[inclined plane]].]]
As of August 21, 2008, the Project on Emerging Nanotechnologies
estimates that over 800 manufacturer-identified nanotech products are publicly available, with new ones hitting the market at a pace of 3–4 per week.
The project lists all of the products in a publicly accessible online database. Most applications are limited to the use of "first generation" passive nanomaterials which includes titanium dioxide in sunscreen, cosmetics, surface coatings, and some food products; Carbon allotropes used to produce gecko tape
; silver in food packaging, clothing, disinfectants and household appliances; zinc oxide in sunscreens and cosmetics, surface coatings, paints and outdoor furniture varnishes; and cerium oxide as a fuel catalyst.
Further applications allow tennis ball
s to last longer, golf ball
s to fly straighter, and even bowling ball
s to become more durable and have a harder surface. Trouser
s and socks
have been infused with nanotechnology so that they will last longer and keep people cool in the summer. Bandage
s are being infused with silver nanoparticles to heal cuts faster.
Video game console
s and personal computer
s may become cheaper, faster, and contain more memory thanks to nanotechnology. Also, to build structures for on chip computing with light, for example on chip optical quantum information processing, and picosecond transmission of information.
Nanotechnology may have the ability to make existing medical applications cheaper and easier to use in places like the general practitioner
's office and at home. Cars are being manufactured with nanomaterial
s so they may need fewer metal
s and less fuel
to operate in the future.
Scientists are now turning to nanotechnology in an attempt to develop diesel engines with cleaner exhaust fumes. Platinum is currently used as the diesel engine catalyst
in these engines. The catalyst is what cleans the exhaust fume particles. First a reduction catalyst is employed to take nitrogen atoms from NOx molecules in order to free oxygen. Next the oxidation catalyst oxidizes the hydrocarbons and carbon monoxide to form carbon dioxide and water. Platinum is used in both the reduction and the oxidation catalysts. Using platinum though, is inefficient in that it is expensive and unsustainable. Danish company InnovationsFonden invested DKK 15 million in a search for new catalyst substitutes using nanotechnology. The goal of the project, launched in the autumn of 2014, is to maximize surface area and minimize the amount of material required. Objects tend to minimize their surface energy; two drops of water, for example, will join to form one drop and decrease surface area. If the catalyst's surface area that is exposed to the exhaust fumes is maximized, efficiency of the catalyst is maximized. The team working on this project aims to create nanoparticles that will not merge. Every time the surface is optimized, material is saved. Thus, creating these nanoparticles will increase the effectiveness of the resulting diesel engine catalyst—in turn leading to cleaner exhaust fumes—and will decrease cost. If successful, the team hopes to reduce platinum use by 25%.
Nanotechnology also has a prominent role in the fast developing field of Tissue Engineering
. When designing scaffolds, researchers attempt to mimic the nanoscale features of a cell
's microenvironment to direct its differentiation down a suitable lineage. For example, when creating scaffolds to support the growth of bone, researchers may mimic osteoclast
Researchers have successfully used DNA origami
-based nanobots capable of carrying out logic functions to achieve targeted drug delivery in cockroaches. It is said that the computational power of these nanobots can be scaled up to that of a Commodore 64
Commercial nanoelectronic semiconductor device fabrication
began in the 2010s. In 2013, SK Hynix
began commercial mass-production of a 16nm
began production of a 16nm FinFET
process, and Samsung Electronics
began production of a 10nm
began production of a 7 nm
process in 2017,
and Samsung began production of a 5 nm
process in 2018. In 2019, Samsung announced plans for the commercial production of a 3nm GAAFET
process by 2021.
Commercial production of nanoelectronic semiconductor memory
also began in the 2010s. In 2013, SK Hynix
began mass-production of 16nm NAND flash
began production of 10nm multi-level cell
(MLC) NAND flash memory.
In 2017, TSMC
began production of SRAM
memory using a 7 nm
An area of concern is the effect that industrial-scale manufacturing and use of nanomaterials would have on human health and the environment, as suggested by nanotoxicology
research. For these reasons, some groups advocate that nanotechnology be regulated by governments. Others counter that overregulation would stifle scientific research and the development of beneficial innovations. Public health
research agencies, such as the National Institute for Occupational Safety and Health
are actively conducting research on potential health effects stemming from exposures to nanoparticles.
Some nanoparticle products may have unintended consequences
. Researchers have discovered that bacteriostatic
silver nanoparticles used in socks to reduce foot odor are being released in the wash. These particles are then flushed into the waste water stream and may destroy bacteria which are critical components of natural ecosystems, farms, and waste treatment processes.
Public deliberations on risk perception
in the US and UK carried out by the Center for Nanotechnology in Society found that participants were more positive about nanotechnologies for energy applications than for health applications, with health applications raising moral and ethical dilemmas such as cost and availability.
[Harthorn, Barbara Herr (January 23, 2009]
"People in the US and the UK show strong similarities in their attitudes toward nanotechnologies"
. Nanotechnology Today.
Experts, including director of the Woodrow Wilson Center's Project on Emerging Nanotechnologies David Rejeski, have testified that successful commercialization depends on adequate oversight, risk research strategy, and public engagement. Berkeley, California
is currently the only city in the United States to regulate nanotechnology; Cambridge, Massachusetts
in 2008 considered enacting a similar law, but ultimately rejected it.
Health and environmental concerns
Nanofibers are used in several areas and in different products, in everything from aircraft wings to tennis rackets. Inhaling airborne nanoparticles and nanofibers may lead to a number of pulmonary disease
s, e.g. fibrosis
. Researchers have found that when rats breathed in nanoparticles, the particles settled in the brain and lungs, which led to significant increases in biomarkers for inflammation and stress response and that nanoparticles induce skin aging through oxidative stress in hairless mice.
A two-year study at UCLA's School of Public Health found lab mice consuming nano-titanium dioxide showed DNA and chromosome damage to a degree "linked to all the big killers of man, namely cancer, heart disease, neurological disease and aging".
A major study published more recently in Nature Nanotechnology
suggests some forms of carbon nanotubes – a poster child for the "nanotechnology revolution" – could be as harmful as asbestos
if inhaled in sufficient quantities. Anthony Seaton
of the Institute of Occupational Medicine in Edinburgh, Scotland, who contributed to the article on carbon nanotube
s said "We know that some of them probably have the potential to cause mesothelioma. So those sorts of materials need to be handled very carefully." In the absence of specific regulation forthcoming from governments, Paull and Lyons (2008) have called for an exclusion of engineered nanoparticles in food. A newspaper article reports that workers in a paint factory developed serious lung disease and nanoparticles were found in their lungs.
[Nanofibres 'may pose health risk']
. BBC. 2012-08-24
Calls for tighter regulation of nanotechnology have occurred alongside a growing debate related to the human health and safety risks of nanotechnology. There is significant debate about who is responsible for the regulation of nanotechnology. Some regulatory agencies currently cover some nanotechnology products and processes (to varying degrees) – by "bolting on" nanotechnology to existing regulations – there are clear gaps in these regimes. Davies (2008) has proposed a regulatory road map describing steps to deal with these shortcomings.
Stakeholders concerned by the lack of a regulatory framework to assess and control risks associated with the release of nanoparticles and nanotubes have drawn parallels with bovine spongiform encephalopathy
("mad cow" disease), thalidomide
, genetically modified food, nuclear energy, reproductive technologies, biotechnology, and asbestosis
. Dr. Andrew Maynard, chief science advisor to the Woodrow Wilson Center's Project on Emerging Nanotechnologies, concludes that there is insufficient funding for human health and safety research, and as a result there is currently limited understanding of the human health and safety risks associated with nanotechnology. As a result, some academics have called for stricter application of the precautionary principle
, with delayed marketing approval, enhanced labelling and additional safety data development requirements in relation to certain forms of nanotechnology.
The Royal Society report
identified a risk of nanoparticles or nanotubes being released during disposal, destruction and recycling, and recommended that "manufacturers of products that fall under extended producer responsibility regimes such as end-of-life regulations publish procedures outlining how these materials will be managed to minimize possible human and environmental exposure" (p. xiii).
The Center for Nanotechnology in Society has found that people respond to nanotechnologies differently, depending on application – with participants in public deliberations
more positive about nanotechnologies for energy than health applications – suggesting that any public calls for nano regulations may differ by technology sector.
* Carbon nanotube
* Electrostatic deflection (molecular physics/nanotechnology)
* Energy applications of nanotechnology
* Ethics of nanotechnologies
* Ion implantation-induced nanoparticle formation
* Gold nanoparticle
* List of emerging technologies
* List of nanotechnology organizations
* List of software for nanostructures modeling
* Magnetic nanochains
* Molecular design software
* Molecular mechanics
* Nanoelectromechanical relay
* Nanoscale networks
* Nanotechnology education
* Nanotechnology in fiction
* Nanotechnology in water treatment
* National Nanotechnology Initiative
* Self-assembly of nanoparticles
* Top-down and bottom-up
* Translational research
* Wet nanotechnology
What is Nanotechnology?
(A Vega/BBC/OU Video Discussion).
Category:Articles containing video clips