U.S. Route 322 (US 322) is a spur of

US 22 U.S. Route 22 (US 22) is a west–east route and is one of the original United States highways of 1926, running from Cincinnati, Ohio, at U.S. Route 27, US 27, U.S. Route 42, US 42, U.S. Route 127, US 127, and U.S. Route 52, US 52 to Newark, New ...

, running from

Cleveland, Ohio Cleveland ( ), officially the City of Cleveland, is a city in the U.S. state of Ohio and the county seat of Cuyahoga County. Located in the northeastern part of the state, it is situated along the southern shore of Lake Erie, across the U.S. ...

, east to

Atlantic City, New Jersey Atlantic City, often known by its initials A.C., is a coastal resort city in Atlantic County, New Jersey, United States. The city is known for its casinos, boardwalk, and beaches. In 2020, the city had a population of 38,497.

. In the

U.S. state In the United States, a state is a constituent political entity, of which there are 50. Bound together in a political union, each state holds governmental jurisdiction over a separate and defined geographic territory where it shares its sover ...

Pennsylvania Pennsylvania (; ( Pennsylvania Dutch: )), officially the Commonwealth of Pennsylvania, is a state spanning the Mid-Atlantic, Northeastern, Appalachian, and Great Lakes regions of the United States. It borders Delaware to its southeast, ...

, the route runs from the

Ohio Ohio () is a state in the Midwestern region of the United States. Of the fifty U.S. states, it is the 34th-largest by area, and with a population of nearly 11.8 million, is the seventh-most populous and tenth-most densely populated. The sta ...

state line in West Shenango Township southeast to the

Commodore Barry Bridge The Commodore Barry Bridge (also known as the Commodore John Barry Bridge or John Barry Bridge) is a cantilever bridge that spans the Delaware River from Chester, Pennsylvania to Bridgeport, in Logan Township, New Jersey. It is named after the ...

over the

Delaware River The Delaware River is a major river in the Mid-Atlantic (United States), Mid-Atlantic region of the United States. From the meeting of its branches in Hancock (village), New York, Hancock, New York, the river flows for along the borders of N ...

Chester Chester is a cathedral city and the county town of Cheshire, England. It is located on the River Dee, close to the English–Welsh border. With a population of 79,645 in 2011,"2011 Census results: People and Population Profile: Chester Loca ...

, at which point the route crosses into

New Jersey New Jersey is a state in the Mid-Atlantic and Northeastern regions of the United States. It is bordered on the north and east by the state of New York; on the east, southeast, and south by the Atlantic Ocean; on the west by the Delaware ...

. The route passes near or through several cities, including Meadville, DuBois,

State College State College is a city in central Pennsylvania, United States. State College may also refer to: Related to State College, Pennsylvania * State College Area School District, a school district serving State College * State College Area High School ...

, and

Harrisburg Harrisburg is the capital city of the Pennsylvania, Commonwealth of Pennsylvania, United States, and the county seat of Dauphin County, Pennsylvania, Dauphin County. With a population of 50,135 as of the 2021 census, Harrisburg is the List of c ...

. US 322 in Pennsylvania is named the 28th Division Highway in honor of the 28th Infantry Division.

Route description

In Pennsylvania, US 322 is signed as 28th Division Highway, in honor of the 28th Infantry Division.

Ohio to Brookville

US 322 enters Pennsylvania from

Crawford County Crawford County is the name of eleven counties in the United States: * Crawford County, Arkansas * Crawford County, Georgia * Crawford County, Illinois * Crawford County, Indiana * Crawford County, Iowa * Crawford County, Kansas * Crawford County, ...

, heading southeast on two-lane undivided Williamsfield Road. The road runs through rural areas on the southwest border of Pymatuning State Park, which is home to the

Pymatuning Reservoir Pymatuning Reservoir is a man-made lake in Crawford County, Pennsylvania and Ashtabula County, Ohio in the United States, on land that was once a very large swamp. Much of it is incorporated into two state parks: Pymatuning State Park in Pennsyl ...

. Past the state park, the route crosses into Mercer County and heads into the borough of Jamestown, becoming Gibson Street and coming to an intersection with PA 58. At this point, the two routes head east for a

concurrency Concurrent means happening at the same time. Concurrency, concurrent, or concurrence may refer to: Law * Concurrence, in jurisprudence, the need to prove both ''actus reus'' and ''mens rea'' * Concurring opinion (also called a "concurrence"), a ...

along Liberty Street, crossing the

Shenango River The Shenango River is a principal tributary of the Beaver River, approximately 100 mi (160 km) long,Hartstown, where it becomes Liberty Street and reaches an intersection with PA 18. At this point, PA 18 turns northeast for a concurrency with US 322 and the road comes to a bridge over the

Canadian National The Canadian National Railway Company (french: Compagnie des chemins de fer nationaux du Canada) is a Canadian Class I railroad, Class I freight railway headquartered in Montreal, Quebec, which serves Canada and the Midwestern United States, M ...

Bessemer Subdivision The Bessemer and Lake Erie Railroad is a class II railroad that operates in northwestern Pennsylvania and northeastern Ohio. The railroad's main route runs from the Lake Erie port of Conneaut, Ohio, to the Pittsburgh suburb of Penn Hills, Penns ...

railroad line as it curves northeast and continues as an unnamed road. Farther northeast, the road enters the borough of

Conneaut Lake Conneaut Lake is the largest natural lake in Pennsylvania by surface area. It is located in western Crawford County near a town with the same name. Its has a surface area of approximately 925 acres. The site of the lake is actually in adjacent ...

and becomes State Street, turning north onto South 4th Street to come to an intersection with

US 6 U.S. Route 6 (US 6), also called the Grand Army of the Republic Highway, honoring the American Civil War veterans association, is a main route of the U.S. Highway system. While it currently runs east-northeast from Bishop, California, to ...

/ PA 285 in the center of the borough. At this point, US 322/PA 18 turn east to join US 6 and PA 285 on Water Street. A block later, PA 285 splits to the south. US 6/US 322/PA 18 become a five-lane road with a

center left-turn lane A reversible lane (British English: tidal flow) is a lane in which traffic may travel in either direction, depending on certain conditions. Typically, it is meant to improve traffic flow during rush hours, by having overhead traffic lights and li ...

and head east out of the borough, passing to the south of

. PA 18 splits from US 6/US 322 by turning to the north, with US 6/US 322 continuing east-northeast on Conneaut Lake Road. The road heads into a business area to the west of the city of Meadville and comes to a

roundabout A roundabout is a type of circular intersection or junction in which road traffic is permitted to flow in one direction around a central island, and priority is typically given to traffic already in the junction.''The New Shorter Oxford En ...

with

US 19 U.S. Route 19 (US 19) is a north–south U.S. Highway in the Eastern United States. Despite encroaching Interstate Highways, the route has remained a long-haul road, connecting the Gulf of Mexico with Lake Erie. The highway's southern ...

and the southern terminus of PA 98, at which point US 19 becomes concurrent with US 6 and US 322. The roadway becomes a four-lane

divided highway A dual carriageway ( BE) or divided highway ( AE) is a class of highway with carriageways for traffic travelling in opposite directions separated by a central reservation (BrE) or median (AmE). Roads with two or more carriageways which are ...

and comes to a

cloverleaf interchange A cloverleaf interchange is a two-level interchange in which all turns are handled by slip roads. To go left (in right-hand traffic; reverse directions in left-driving regions), vehicles first continue as one road passes over or under the ...

with

I-79 Interstate 79 (I-79) is an Interstate Highway in the eastern United States, designated from I-77 in Charleston, West Virginia, north to Pennsylvania Route 5 (PA 5) and PA 290 in Erie, Pennsylvania. It is a primary thoroughfare ...

. Past this interchange, the three routes reach an intersection with the southern terminus of PA 102 before curving north and entering Meadville upon crossing French Creek and a Western New York and Pennsylvania Railroad line. The road becomes French Creek Parkway before US 322 splits from US 6 and US 19 by turning to the east onto two-lane undivided Linden Street. The route runs through developed areas and turns south onto South Main Street before leaving Meadville. The road becomes Cochranton Road and runs through rural areas to the east of French Creek and the Western New York and Pennsylvania Railroad line. US 322 curves to the southeast and the name changes to Meadville Road. The route becomes an unnamed road and passes through the northern part of the borough of

Cochranton Cochranton is a borough in Crawford County, Pennsylvania, United States. The population was 1,124 at the 2020 census, down from 1,136 as of the 2010 census. Geography Cochranton is located on the southern boundary of Crawford County at (41.5194 ...

before it comes to an intersection with PA 173. Past this intersection, the road curves to the south. The route crosses into Mercer County, where it makes a turn to the east. US 322 heads into

Venango County Venango County is a county in the Commonwealth of Pennsylvania. As of the 2020 census, the population was 50,454. Its county seat is Franklin. The county was created in 1800 and later organized in 1805. Venango County comprises the Oil City, ...

and runs east, curving southeast in the community of Hannasville. The road enters the borough of Sugarcreek, where it crosses Sugar Creek and comes to an intersection with the southern terminus of PA 427. From here, the route curves south to run east of the parallel Sugar Creek before turning east and running north of French Creek and the Western New York and Pennsylvania Railroad line. US 322 turns south alongside the creek and railroad tracks before it curves east and enters the city of

Franklin Franklin may refer to: People * Franklin (given name) * Franklin (surname) * Franklin (class), a member of a historical English social class Places Australia * Franklin, Tasmania, a township * Division of Franklin, federal electoral d ...

. At this point, the road becomes Grant Street and passes through developed areas of the city, curving northeast and back to the east. US 322 reaches an intersection with the southern terminus of PA 417, at which point it turns south onto four-lane undivided 13th Street, crossing the Western New York and Pennsylvania Railroad line at-grade. The road turns into a divided highway and crosses French Creek, becoming undivided again and heading into the downtown area of Franklin. US 322 comes to an intersection with

US 62 U.S. Route 62 or U.S. Highway 62 (US 62) runs from the Mexican border at El Paso, Texas, to Niagara Falls, New York, near the Canadian border. It is the only east-west United States Numbered Highway that connects Mexico and Canada ...

/ PA 8, at which point it turns east for a concurrency with the two routes on four-lane undivided Liberty Street. The road turns southeast and leaves the downtown area, narrowing to one lane westbound before US 62/PA 8 split from US 322 by turning to the northeast. US 322 continues south along two-lane undivided Liberty Street before it turns east onto 8th Street and crosses the

Allegheny River The Allegheny River ( ) is a long headwater stream of the Ohio River in western Pennsylvania and New York (state), New York. The Allegheny River runs from its headwaters just below the middle of Pennsylvania's northern border northwesterly into ...

, leaving Franklin. From here, the route becomes an unnamed road and curves south parallel to the river, running through rural areas. The road turns to the east and passes through the community of Venango before the Allegheny River curves south away from the road, with the road gaining a second eastbound lane as it climbs a hill. US 322 narrows to two lanes prior to reaching the community of

Cranberry Cranberries are a group of evergreen dwarf shrubs or trailing vines in the subgenus ''Oxycoccus'' of the genus ''Vaccinium''. In Britain, cranberry may refer to the native species ''Vaccinium oxycoccos'', while in North America, cranberry ...

. Here, the route passes businesses and heads to the south of the Cranberry Mall before it intersects the southern terminus of PA 257. Past this intersection, the road runs through rural land, crossing East Sandy Creek and reaching a junction with the northern terminus of PA 38. Susquehanna and Waterford Turnpike milestone in Clarion

Susquehanna and Waterford Turnpike milestone in Clarion

US 322 enters

Clarion County Clarion County is a county in the Commonwealth of Pennsylvania. As of the 2020 census, the population was 37,241. Its county seat is Clarion. The county was formed on March 11, 1839, from parts of Venango and Armstrong counties. Clarion Cou ...

and continues southeast, intersecting the eastern terminus of PA 338 in the community of Kossuth. Farther east, the road reaches the borough of Shippenville. Upon entering Shippenville, the route becomes Main Street and intersects PA 208. At this point, PA 208 joins US 322 in a concurrency before it splits to the north. The route leaves Shippenville and becomes unnamed again, passing south of a residential development. The road reaches an intersection with

PA 66 Pennsylvania Route 66 (PA 66) is a state highway in Western Pennsylvania. Its southern terminus is at U.S. Route 119 (US 119) just east of Interstate 70 (I-70) near New Stanton. Its northern terminus is at US 6 in Kane. The southernmost ...

near businesses in the community of

Marianne Marianne () has been the national personification of the French Republic since the French Revolution, as a personification of liberty, equality, fraternity and reason, as well as a portrayal of the Goddess of Liberty. Marianne is displayed i ...

. Past this intersection, US 322 runs southeast through rural areas before it gains a second westbound lane as it descends a hill. The route narrows to two lanes and curves east, crossing the

Clarion River The Clarion River is a tributary of the Allegheny River, approximately 110 mi (177 km) long, in west central Pennsylvania in the United States. It drains a rugged area of the Allegheny Plateau in the Ohio River watershed, flowing throu ...

. After crossing the river, the road gains a second eastbound lane as it ascends a hill. US 322 curves south and enters the borough of

Clarion Clarion may refer to: Music * Clarion (instrument), a type of trumpet used in the Middle Ages * The register of a clarinet that ranges from B4 to C6 * A trumpet organ stop that usually plays an octave above unison pitch * "Clarion" (song), a 2 ...

, where it narrows to two lanes and becomes North 1st Avenue, running through developed areas and passing east of Memorial Stadium. The route turns southeast onto Main Street and heads into the downtown area of Clarion, where it intersects the eastern terminus of PA 68. After leaving the downtown area, the road passes through the

PennWest Clarion Pennsylvania Western University, Clarion, also known as PennWest Clarion, is a public university campus in Clarion, Pennsylvania. Part of the Pennsylvania State System of Higher Education (PASSHE), the institution was founded in 1867 and offers ...

university campus. US 322 leaves Clarion and becomes an unnamed road, passing east through rural areas. Farther east, the route enters the borough of Strattanville and runs east through the borough along Main Street. The road leaves Strattanville and becomes unnamed, heading east-southeast and reaching a

partial cloverleaf interchange A partial cloverleaf interchange or parclo is a modification of a cloverleaf interchange. The design has been well received, and has since become one of the most popular freeway-to-arterial interchange designs in North America. It has also bee ...

with

I-80 Interstate 80 (I-80) is an east–west transcontinental freeway that crosses the United States from downtown San Francisco, California, to Teaneck, New Jersey, in the New York metropolitan area. The highway was designated in 1956 as one o ...

. US 322 crosses into Jefferson County and enters the borough of

Corsica Corsica ( , Upper , Southern ; it, Corsica; ; french: Corse ; lij, Còrsega; sc, Còssiga) is an island in the Mediterranean Sea and one of the 18 regions of France. It is the fourth-largest island in the Mediterranean and lies southeast of ...

, where it becomes Main Street, forming a concurrency with PA 949 before that route splits to the south. Upon leaving Corsica, the route turns into an unnamed road and runs a short distance to the south of I-80, passing through the community of Roseville and curving to the east-southeast.

Brookville to State College

Farther east, the road enters the borough of Brookville and becomes West Main Street, continuing into an area of businesses and coming to an intersection where PA 28 heads south and PA 36 and PA 28 Truck heads north. At this point, US 322 forms a concurrency with PA 28 and PA 36, running through developed areas of the borough. The road becomes Main Street and PA 36 splits from US 322/PA 28 by heading to the south, with US 322/PA 28 continuing east through the downtown area of Brookville. The road curves northeast and southeast out of the downtown area before crossing the

North Fork Creek North Fork Creek is a tributary of Redbank Creek in northwest Pennsylvania in the United States.Gertler, Edward. ''Keystone Canoeing'', Seneca Press, 2004. It is formed by the confluence of Muddy Run and Williams Run in Polk Township, Jefferson C ...

and running east along East Main Street. On the eastern border of Brookville, PA 28 splits to the east and US 322 continues southeast through rural areas as an unnamed road, crossing Mill Creek in the community of Port Barnett. The route passes through the community of Emerickville as it continues along. Farther east, the road turns to the south and enters the borough of Reynoldsville, where the name becomes West Main Street and it curves east. US 322 continues southeast and comes to an intersection with the southern terminus of PA 950 before it crosses a

Buffalo and Pittsburgh Railroad The Buffalo and Pittsburgh Railroad is a Class II railroad operating in New York and Pennsylvania. The BPRR is owned by Genesee & Wyoming. Its main line runs between Buffalo, New York and Eidenau, Pennsylvania, north of Pittsburgh. Here, conne ...

line at-grade and

Sandy Lick Creek Sandy Lick Creek is a tributary of Redbank Creek in northwest Pennsylvania in the United States.Gertler, Edward. ''Keystone Canoeing'', Seneca Press, 2004. Sandy Lick Creek arises in Sandy Township north of Lake Sabula and joins North Fork Cre ...

. The route becomes East Main Street and runs through the downtown area of Reynoldsville, where it has a junction with the northern terminus of PA 310. US 322 leaves Reynoldsville becomes an unnamed road and continues through rural areas, curving northeast in the community of Prescottville. The route continues east and runs through the community of Rathmel. US Route 322 - Pennsylvania (4162562071)

US Route 322 - Pennsylvania (4162562071)

US 322 enters

Clearfield County Clearfield County is a county in the Commonwealth of Pennsylvania. As of the 2020 census, the population was 80,562. The county seat is Clearfield, and the largest city is DuBois. The county was created in 1804 and later organized in 1822. C ...

and runs east-southeast along Behringer Highway, coming to an intersection with

US 119 U.S. Route 119 (US 119) is a spur of US 19. It is a north–south route (on a northeast-southwest alignment) that was an original United States highway of 1926. It is Corridor G of the Appalachian Development Highway System (ADHS) east of US ...

south of the city of DuBois. The route continues east and reaches a junction with

US 219 U.S. Route 219 (US 219) is a spur of US 19. It runs for from West Seneca, New York, at an interchange with Interstate 90 (I-90) to Rich Creek, Virginia, intersecting at US 460. US 219 is found (from north to south) in New York, Pennsylvania, Ma ...

, where it briefly becomes a divided highway. At this point, US 219 joins US 322 in a concurrency along two-lane undivided Carson Hill Road. The two routes pass over a Buffalo and Pittsburgh Railroad line and head southeast, passing through the community of

Salem Salem may refer to: Places Canada Ontario * Bruce County ** Salem, Arran–Elderslie, Ontario, in the municipality of Arran–Elderslie ** Salem, South Bruce, Ontario, in the municipality of South Bruce * Salem, Dufferin County, Ontario, part ...

. The road reaches the community of Luthersburg, where it intersects the eastern terminus of PA 410. The two routes curve east onto Luthersburg-Rockton Road and US 219 splits from US 322 by turning to the south. US 322 continues east, curving northeast before reaching the community of Rockton. In Rockton, the route turns east and becomes Rockton Mountain Highway, entering the

Moshannon State Forest Moshannon State Forest is a List of Pennsylvania state forests, Pennsylvania State Forest in Pennsylvania Bureau of Forestry District #9. The main offices are located in the unincorporated area, unincorporated village of Penfield in Huston Towns ...

. Upon entering the state forest, the road turns southeast, crossing Anderson Creek, and then turning northeast before curving to the east. Farther east, US 322 reaches an intersection with PA 153, where it turns southeast to form a concurrency with that route on four-lane divided Rockton Mountain Highway. The road leaves the Moshannon State Forest and continues through rural areas. The two routes enter more developed areas north of the borough of Clearfield as a three-lane road with a center left-turn lane, crossing a R.J. Corman Railroad line at-grade. US 322/PA 153 curve south onto West Front Street and enter the borough of Clearfield. The two routes turn southeast onto two-lane Nichols Street and cross the

West Branch Susquehanna River The West Branch Susquehanna River is one of the two principal branches, along with the North Branch, of the Susquehanna River in the Northeastern United States. The North Branch, which rises in upstate New York, is generally regarded as the exte ...

, with the road name becoming Bridge Street. PA 153 splits from US 322 on the east bank of the river by turning south, with US 322 continuing east along Bridge Street before curving north onto Bigler Avenue. The route turns east-southeast as it continues through the borough. The road leaves Clearfield and becomes Daisy Street, turning into a divided highway as it reaches a partial cloverleaf interchange with PA 879. Past this interchange, US 322 becomes undivided again and runs through developed areas, crossing a R.J. Corman Railroad line at-grade and

Clearfield Creek Clearfield Creek is a U.S. Geological Survey. National Hydrography Dataset high-resolution flowline dataThe National Map, accessed August 8, 2011 tributary of the West Branch Susquehanna River in Cambria and Clearfield counties, Pennsylvania, in ...

. The route gains a center left-turn lane and the name changes to Clearfield Woodland Highway, passing south of the Clearfield Campus of

Lock Haven University of Pennsylvania Lock Haven University of Pennsylvania (LHU) is a public university in Lock Haven, Pennsylvania. It is part of the Pennsylvania State System of Higher Education. The main campus consists of and the branch campus covers . It offers 69 undergraduat ...

. The road narrows to two lanes and it runs through rural areas, turning south and gaining a second eastbound lane before a turn to the east. US 322 narrows back to two lanes and passes through the community of

Mineral Springs Mineral springs are naturally occurring springs that produces hard water, water that contains dissolved minerals. Salts, sulfur compounds, and gases are among the substances that can be dissolved in the spring water during its passage underg ...

before it comes to an intersection with the southern terminus of PA 970, where the name changes to Woodland Bigler Highway. The route curves to the southeast before gaining a center left-turn lane and turning to the south, intersecting Bigler Cutoff Road. The road becomes Philipsburg Bigler Highway and narrows back to two lanes, crossing a R.J. Corman Railroad line at-grade. US 322 curves southeast and passes through the southwest corner of the borough of Wallaceton before it runs parallel to the railroad tracks. Farther southeast, the route gains a center left-turn lane as it enters business areas along North Front Street, crossing the R.J. Corman Railroad tracks and coming to an intersection with PA 53, where PA 53 turns southeast for a concurrency with US 322 along a two-lane road. Upon crossing

Moshannon Creek Moshannon Creek is a U.S. Geological Survey. National Hydrography Dataset high-resolution flowline dataThe National Map accessed August 8, 2011 tributary of the West Branch Susquehanna River in Centre County, Pennsylvania in the United States.Gertl ...

, US 322/PA 53 enters

Centre County Centre County is a county in the Commonwealth of Pennsylvania. As of the 2020 census, the population was 158,172. Its county seat is Bellefonte. Centre County comprises the State College, PA Metropolitan Statistical Area. History The lands ...

and heads east past developed areas along North Centre Street, which carries two eastbound lanes and one westbound lane. Upon reaching the northern border of the borough of Philipsburg, US 322 splits from PA 53 by turning northeast onto Railroad Street, a three-lane road with a center left-turn lane. The route narrows to two lanes and enters Philipsburg, curving to the southeast. The road turns south and intersects

PA 504 Pennsylvania Route 504 (PA 504) is a state highway located in Centre County in the U.S. state of Pennsylvania. The western terminus is at PA 53/ PA 350 in Philipsburg. The eastern terminus is at US 220 Alternate/PA 144 in Wingate. It roug ...

before heading southeast again and leaving Philipsburg. US 322 becomes Port Matilda Highway and passes a westbound

runaway truck ramp A runaway truck ramp, runaway truck lane, escape lane, emergency escape ramp, or truck arrester bed is a traffic device that enables vehicles which are having braking problems to safely stop. It is typically a long, sand- or gravel-filled lane co ...

as it runs through rural areas, ascending Black Bear Hill. The road passes a westbound truck brake check station and curves east and then south. The route makes a turn to the southeast and comes to a

rest area A rest area is a public facility located next to a large thoroughfare such as a motorway, expressway, or highway, at which drivers and passengers can rest, eat, or refuel without exiting onto secondary roads. Other names include motorway servi ...

accessible from both directions on the westbound side of the road, crossing Sandy Ridge. US 322 becomes a four-lane divided highway with a wide median called Flat Rock Road, curving east into the Moshannon State Forest before turning southeast and leaving the state forest. The route intersects Reese Hollow Road/East Mountain Road, with access via an at-grade intersection eastbound and an interchange westbound. Following this, the median narrows and the four-lane divided highway enters the

Bald Eagle Valley Bald Eagle Valley is a low-lying area in Pennsylvania that drains into Bald Eagle Creek between the Allegheny Front and Bald Eagle Mountain, south of the West Branch Susquehanna River, in the Ridge-and-valley Appalachians. The valley is located s ...

, coming to an eastbound exit and westbound entrance with North High Street that provides access to the borough of Port Matilda. At this point, US 322 becomes an unnamed

freeway A controlled-access highway is a type of highway that has been designed for high-speed vehicular traffic, with all traffic flow—ingress and egress—regulated. Common English terms are freeway, motorway and expressway. Other similar terms ...

and continues east to a westbound exit and eastbound entrance with I-99/

US 220 U.S. Route 220 (US 220) is a spur route of US 20. It runs in a north–south layout in the eastern United States, unlike its parent route as well as conventionally even-numbered highways which run east-west. US 220 extends for fr ...

, at which point it joins I-99/US 220; North High Street provides the missing movements at this interchange. I-99/US 220/US 322 run east, passing over US 220 Alt. and a

Nittany and Bald Eagle Railroad The Nittany and Bald Eagle Railroad is a short line railroad that operates of track in Blair, Centre, and Clinton counties in Pennsylvania in the United States. It is part of the North Shore Railroad System. The line runs generally northea ...

line before curving northeast. The freeway heads across

Bald Eagle Mountain Bald Eagle Mountain – once known locally as Muncy Mountain – is a stratigraphic ridge in the Ridge-and-Valley Appalachians of central Pennsylvania, United States, running east of the Allegheny Front and northwest of Mount Nittany. It lies alon ...

before it turns east and then southeast into the

Nittany Valley Nittany Valley is an eroded anticlinal valley located in Centre County, Pennsylvania. It is separated from the Bald Eagle Valley by Bald Eagle Mountain and from Penns Valley by Mount Nittany. The valley is closed to the north by a high plateau t ...

, passing over PA 550 before reaching a partial cloverleaf interchange with Grays Woods Boulevard that provides access to the communities of Grays Woods and

Waddle Waddle may refer to: * Waddle, Pennsylvania, United States * Waddle (surname) Waddle is a surname. Notable people with the surname include: * Alan Waddle (born 1954), English footballer * Bryan Waddle (21st century), New Zealand broadcaster * C ...

State College to Harrisburg

I-99/US 220/US 322 come to an eastbound exit and westbound entrance with the western terminus of US 322 Bus., which heads east into the borough of

. At this point, the freeway becomes the Mount Nittany Expressway and bypasses State College to the north. A short distance later, the freeway reaches a westbound exit and eastbound entrance with Valley Vista Drive that serves the community of Park Forest. From here, the road passes through a mix of rural and developed areas, coming to a

diamond interchange A diamond interchange is a common type of road junction, used where a controlled-access highway crosses a minor road. Design The freeway itself is grade-separated from the minor road, one crossing the other over a bridge. Approaching the ...

with Waddle Road that serves the communities of

Toftrees Toftrees is a village and former civil parish, now in the parish of Dunton, in the North Norfolk district, in the county of Norfolk, England. The hamlet is 2.3 miles south west of Fakenham, 27.3 miles north west of Norwich and 113 miles north n ...

and Woodycrest. I-99/US 220/US 322 continues east before reaching the Mount Nittany Interchange, a

directional T interchange In the field of road transport, an interchange (American English) or a grade-separated junction (British English) is a road junction that uses grade separations to allow for the movement of traffic between two or more roadways or highways, using ...

where I-99/US 220 splits from US 322 by heading to the northeast. Also at the Mount Nittany Interchange, US 322 has a partial cloverleaf interchange with Park Avenue that provides access to the University Park campus of

Pennsylvania State University The Pennsylvania State University (Penn State or PSU) is a Public university, public Commonwealth System of Higher Education, state-related Land-grant university, land-grant research university with campuses and facilities throughout Pennsylvan ...

, including

Beaver Stadium Beaver Stadium is an outdoor college football stadium on the campus of Pennsylvania State University in University Park, Pennsylvania. It has been home to the Penn State Nittany Lions of the Big Ten Conference since 1960, though some parts of ...

and the

Bryce Jordan Center The Bryce Jordan Center is a 15,261-seat multi-purpose arena in University Park, Pennsylvania, United States, on the University Park campus of the Pennsylvania State University. The arena opened in 1996 and is the largest such venue between ...

, and the Innovation Park business and research park. From here, US 322 continues southeast on the Mount Nittany Expressway, coming to a diamond interchange with PA 26 that serves State College. At this point, US 322 becomes concurrent with PA 144 Truck. The freeway winds south before heading to the southeast and then to the east. The route comes to a partial cloverleaf interchange with Boalsburg Road/Warner Boulevard that provides access to PA 45 and the community of Boalsburg. US 322 turns to the southeast to reach and eastbound exit and westbound entrance with PA 45, where it narrows from a four-lane freeway to a

two-lane expressway A two-lane expressway or two-lane freeway is an expressway or freeway with only one lane in each direction, and usually no median barrier. It may be built that way because of constraints, or may be intended for expansion once traffic volumes ris ...

. A short distance later, the Mount Nittany Expressway ends at a westbound exit and eastbound entrance with the eastern terminus of US 322 Bus. From here, US 322 continues east along Boal Avenue, a two-lane undivided road with at-grade intersections. The road runs through agricultural areas with some development to the north of

Tussey Mountain Tussey Mountain is a stratigraphic ridge in central Pennsylvania, United States, trending east of the Bald Eagle, Brush, Dunning and Evitts Mountain ridges. Its southern foot just crosses the Mason–Dixon line near Flintstone, Maryland, running ...

. Farther east, the route becomes General Potter Highway. US 322 widens into a four-lane divided highway as it comes to a diamond interchange with Old Route 322 that provides access to the southern terminus of

PA 144 Pennsylvania Route 144 (PA 144) is a state highway located in the U.S. state of Pennsylvania, covering a distance of about . The southern terminus is located near an interchange with U.S. Route 322 in Pennsylvania, U.S. Route 322 (US 322) at ...

in the community of Potters Mills, at which point the concurrent PA 144 Truck ends. From here, the route heads south into the

Rothrock State Forest Rothrock State Forest is a Pennsylvania state forest in Pennsylvania Bureau of Forestry District #5. The main offices are located in Huntingdon in Huntingdon County, Pennsylvania in the United States. Rothrock State Forest is located in Centre, ...

and traverses the Seven Mountains, which includes Tussey Mountain and

Stone Mountain Stone Mountain is a quartz monzonite dome Inselberg, monadnock and the site of Stone Mountain Park, east of Atlanta, Georgia. Outside the park is the small city of Stone Mountain, Georgia. The park is the most visited tourist site in the state o ...

. The road comes to an interchange with Sand Mountain Road before it makes a curve to the southwest. US 322 crosses into

Mifflin County Mifflin County is a county in the Commonwealth of Pennsylvania. As of the 2020 census, the population was 46,143. Its county seat is Lewistown. The county was created on September 19, 1789, from parts of Cumberland County and Northumberlan ...

and becomes an unnamed road, coming to an eastbound truck brake check station. At this point, the route begins to descend the Seven Mountains, passing between Rothrock State Forest to the west and

Bald Eagle State Forest Bald Eagle State Forest is a Pennsylvania state forest in Pennsylvania Bureau of Forestry District #7. The main office is located in Laurelton in Union County, Pennsylvania. The forest is found in Centre, Clinton, Mifflin, Snyder, and Union ...

to the east. The road turns south and then southwest before it reaches an eastbound runaway truck ramp and makes a curve to the southeast, passing west of the Laurel Creek Reservoir. US 322 turns northeast and leaves the state forest, curving east and becoming a freeway. The route turns south through forests and enters the agricultural

Kishacoquillas Valley The Kishacoquillas Valley, known locally as both Kish Valley and Big Valley, is an enclosed anticlinal valley in the Ridge-and-valley Appalachians of Central Pennsylvania, and is located in Mifflin and Huntingdon counties. Geography The vall ...

, where it comes to a trumpet interchange connecting to Old US Hwy 322 that provides access to the community of Milroy. The freeway continues south and reaches a diamond interchange with PA 655 that serves the community of Reedsville. Past this interchange, US 322 runs southeast and crosses the

Kishacoquillas Creek Kishacoquillas Creek (pronounced Kish-e-kō-kwil´-lis) is a U.S. Geological Survey. National Hydrography Dataset high-resolution flowline dataThe National Map , accessed August 8, 2011 tributary of the Juniata River in Mifflin County, Pennsylvania ...

, heading through a gap in

Jacks Mountain Jacks Mountain is a stratigraphic ridge in central Pennsylvania, United States, trending southeast of the Stone Mountain ridge and Jacks Mountain Anticline. The ridge line separates Kishacoquillas Valley from the Ferguson and Dry Valleys. Jacks ...

along with the creek. The route curves south and comes to an interchange with Ferguson Valley Road that provides access to the community of Yeagertown and the borough of

Burnham Burnham may refer to: Places Canada *Burnham, Saskatchewan England *Burnham, Buckinghamshire ** Burnham railway station ** Burnham Grammar School *Burnham Green, Hertfordshire, location of The White Horse * Burnham, Lincolnshire **High Burnham, ...

. The freeway runs through rural areas before passing near development and reaching a directional T interchange with the

US 522 U.S. Route 522 (US 522) is a spur route of US 22 in the states of Virginia, West Virginia, Maryland, and Pennsylvania. The U.S. Highway travels in a north-south direction, and runs from US 60 near Powhatan, Virginia, to its northern terminus a ...

freeway. At this point, US 22/US 522 become concurrent with US 322 and the freeway has an interchange with Electric Avenue. From here, the freeway enters the borough of Lewistown and runs to the west of the Kishacoquillas Creek. US 522 splits from US 22/US 322 at an interchange by heading northeast on East Walnut Street. At the US 522 interchange, the freeway passes over a

Juniata Valley Railroad The Juniata Valley Railroad is a short line that operates 11 miles of track in Mifflin County, Pennsylvania in the United States. It is part of the North Shore Railroad System. The communities served include Lewistown (and the MCIDC industrial ...

line. Past this interchange, US 22/US 322 curves south along the eastern border of Lewistown and crosses a Juniata Valley Railroad line at-grade before reaching an eastbound exit and westbound entrance with East Charles Street. The freeway crosses the Kishacoquillas Creek and leaves Lewistown upon crossing Jacks Creek and heading into rural areas. The two routes curve east and come to a westbound exit and eastbound entrance with the eastern terminus of US 22 Bus., at which point the freeway begins to parallel the

Juniata River The Juniata River () is a tributary of the Susquehanna River, approximately long,U.S. Geological Survey. National Hydrography Dataset high-resolution flowline dataThe National Map , accessed August 8, 2011 in central Pennsylvania. The river is ...

located south of the road. US 22/US 322 curves to the northeast and runs between Shade Mountain to the north and the river to the south as it heads through the Lewistown Narrows

water gap A water gap is a gap that flowing water has carved through a mountain range or mountain ridge and that still carries water today. Such gaps that no longer carry water currents are called wind gaps. Water gaps and wind gaps often offer a prac ...

. This section of road includes the longest

mechanically stabilized earth Mechanically stabilized earth (MSE or reinforced soil) is soil constructed with artificial reinforcing. It can be used for retaining walls, bridge abutments, seawalls, and dikes. Although the basic principles of MSE have been used throughout his ...

wall in the U.S. Fermanagh Township cut

US 22/US 322 enters Juniata County and continues through the water gap, coming to an eastbound access point to a fishing and boating area along the Juniata River. Farther east, the freeway curves to the southeast and exits the Lewistown Narrows, heading further from the river and coming to a diamond interchange with Arch Rock Road. The two routes head northeast and then southeast, crossing Lost Creek before turning south and reaching a diamond interchange with PA 35 east of the borough of

Mifflintown Mifflintown is a borough (Pennsylvania), borough in and the county seat of Juniata County, Pennsylvania, Juniata County, Pennsylvania, United States. The population was 842 at the 2020 United States Census, 2020 census. Geography Mifflintown is ...

. US 22/US 322 comes to a partial cloverleaf interchange with the northern terminus of PA 75 northeast of the borough of

Port Royal Port Royal is a village located at the end of the Palisadoes, at the mouth of Kingston Harbour, in southeastern Jamaica. Founded in 1494 by the Spanish, it was once the largest city in the Caribbean, functioning as the centre of shipping and co ...

. The freeway continues southeast, turning to the east-northeast. Farther east, the two routes come to a partial cloverleaf interchange with PA 333 on the northern border of the borough of Thompsontown. Past Thompsontown, US 22/US 322 has a westbound exit and eastbound entrance with Pfoutz Valley Road. After this interchange, the freeway runs closely parallel to the north bank of the Juniata River as it passes through a water gap in

Tuscarora Mountain Tuscarora Mountain is a mountain ridge of the Appalachian Mountains in the Ridge and Valley province in central Pennsylvania. It reaches its highest point on Big Mountain (Pennsylvania) at above sea level. The mountain is named after the Tuscaro ...

. US 22/US 322 crosses into

Perry County Perry County may refer to: United States *Perry County, Alabama *Perry County, Arkansas *Perry County, Illinois *Perry County, Indiana *Perry County, Kentucky *Perry County, Mississippi *Perry County, Missouri *Perry County, Ohio *Perry Coun ...

, where the freeway and the parallel Juniata River turn southeast out of the water gap. The freeway enters the borough of Millerstown and runs between the river to the west and the borough to the east, passing over PA 17. After leaving the borough, the two routes come to an interchange with West Juniata Parkway that provides access to PA 17 and Millerstown. US 22/US 322 continues through rural areas further east from the Juniata River. The freeway curves south as it passes west of Buffalo Mountain, making a turn east away from the river and reaching a diamond interchange with PA 34 northeast of the borough of Newport. Past this interchange, the two routes begin to parallel the Juniata River again, turning southeast and then east. US 22/US 322 reaches a westbound exit and eastbound entrance with Meadow Grove Road that provides access to the community of Midway and curves southeast alongside the river. The freeway continues south-southeast and reaches an interchange with Huggins Road that serves the community of

Watts Watts is plural for ''watt'', the unit of power. Watts may also refer to: People *Watts (surname), list of people with the surname Watts Fictional characters *Watts, main character in the film '' Some Kind of Wonderful'' *Watts family, six chara ...

; this interchange consists of a left exit and entrance eastbound and a right exit and entrance westbound. The two routes continue south parallel to the Juniata River and reach an interchange connecting to River Road that serves the community of Amity Hall. US 22/US 322 enters

Dauphin County Dauphin County (; Pennsylvania Dutch: Daffin Kaundi) is a county in the Commonwealth of Pennsylvania. As of the 2020 census, the population was 286,401. The county seat and the largest city is Harrisburg, Pennsylvania's state capital and ninth ...

and comes to a modified cloverleaf interchange with the

US 11 {{Infobox road , country=USA , type=US , route=11 , map={{maplink, frame=yes, plain=yes, frame-align=center, frame-width=290, frame-height=330, type=line, from=U.S. Route 11.map , map_custom=yes , map_notes=US 11 in red, US 11E in blue, US 11W in ...

US 15 U.S. Route 15 (US 15) is a -long United States highway, designated along South Carolina, North Carolina, Virginia, Maryland, Pennsylvania, and New York. The route is signed north–south, from U.S. Route 17 Alternate in Walterboro, South Caro ...

freeway. Past this interchange, the freeway ends and the roadway becomes Benvenue Road, a four-lane divided highway. The two routes run through a mix of rural areas and businesses on Duncan Island between the Juniata River to the west and the

Susquehanna River The Susquehanna River (; Lenape: Siskëwahane) is a major river located in the Mid-Atlantic region of the United States, overlapping between the lower Northeast and the Upland South. At long, it is the longest river on the East Coast of the ...

to the east, turning into a five-lane road with a center left-turn lane. US 22/US 322 transitions into a four-lane divided highway and intersects the eastern terminus of PA 849 east of the borough of

Duncannon Duncannon () is a village in southwest County Wexford, Ireland. Bordered to the west by Waterford harbour and sitting on a rocky headland jutting into the channel is the strategically prominent Duncannon Fort which dominates the village. Pri ...

, where the road becomes a freeway again. At this point, the unnamed freeway crosses the Susquehanna River on the

Clarks Ferry Bridge The Clarks Ferry Bridge is a plate girder bridge that carries U.S. Routes 22 and 322 across the Susquehanna River near Duncannon, Pennsylvania, about 20 miles north of Harrisburg, Pennsylvania. It is a 4 lane expressway standard bridge. The bri ...

, which also carries the

Appalachian Trail The Appalachian Trail (also called the A.T.), is a hiking trail in the Eastern United States, extending almost between Springer Mountain in Georgia and Mount Katahdin in Maine, and passing through 14 states.Gailey, Chris (2006)"Appalachian Tr ...

. After crossing the river, the two routes come to a directional T interchange with the southern terminus of PA 147, where the Appalachian Trail splits to the south. Following this interchange, US 22/US 322 turns southwest and runs between the Susquehanna River to the northwest and

Norfolk Southern The Norfolk Southern Railway is a Railroad classes, Class I freight railroad in the United States formed in 1982 with the merger of Norfolk and Western Railway and Southern Railway (U.S.), Southern Railway. With headquarters in Atlanta, the ...

Buffalo Line The Buffalo Line is a railroad line owned by the Norfolk Southern Railway in the U.S. states of New York and Pennsylvania. The line runs from Buffalo, New York southeast to Rockville, Pennsylvania near Harrisburg, Pennsylvania along a former Penns ...

to the southeast. The freeway curves southeast along with the parallel river and railroad tracks as it passes west of

Peters Mountain Peters Mountain is a mountain in the U.S. states of Virginia and West Virginia. It is located on the border between Alleghany County, VA, Monroe County, WV, Giles Co.,VA, and Craig Co.,VA. Its elevation ranges from on the mountaintop to a l ...

. The two routes pass over the Norfolk Southern line and come to a diamond interchange with PA 325 in the community of Speeceville. Past this interchange, US 22/US 322 heads east-southeast through rural areas to the north of the Susquehanna River and Norfolk Southern's Buffalo Line, curving to the east. The freeway reaches a directional T interchange with the southern terminus of PA 225 that serves the borough of Dauphin. From here, the two routes turn southeast and enter the borough of Dauphin, passing near developed areas. The freeway crosses Stony Creek before coming to a westbound exit providing access to Allegheny Street and heading under the railroad line. US 22/US 322 leaves Dauphin and heads southeast between the Susquehanna River to the west and the Norfolk Southern line to the east as it passes west of Second Mountain. Past the mountain, the freeway runs near developed areas farther from the river and comes to a partial cloverleaf interchange with PA 443 in the community of

Fort Hunter Fort Hunter is a hamlet in the Town of Florida in Montgomery County, New York, United States, west of the capital at Albany, on the south bank of the Mohawk River and on the northeast bank of Schoharie Creek. The hamlet developed around a fort of ...

. The two routes continue south-southeast, crossing over Norfolk Southern's Buffalo Line and passing to the west of Blue Mountain. US 22/US 322 heads southeast parallel to Norfolk Southern's

Pittsburgh Line The Pittsburgh Line is the Norfolk Southern Railway's primary east–west artery in its Pittsburgh Division and Harrisburg Division across the U.S. state of Pennsylvania and is part of the Keystone Corridor, Amtrak-Norfolk Southern's combine ...

to the west and reaches a diamond interchange with PA 39, where the parallel railroad line heads further west from the road. At this point, the freeway enters the city of

and runs between Wildwood Park to the west and developed areas to the east, curving south and coming to a

stack interchange A directional interchange, colloquially known as a stack interchange, is a type of grade-separated junction between two controlled-access highways that allows for free-flowing movement to and from all directions of traffic. These interchanges e ...

with

I-81 Interstate 81 (I-81) is a north–south (physically northeast–southwest) Interstate Highway in the eastern part of the United States. Its southern terminus is at I-40 in Dandridge, Tennessee; its northern terminus is on Wellesley Island ...

. At this point, US 322 splits from US 22 by heading east concurrent with I-81 while US 22 continues south toward

Downtown Harrisburg Downtown Harrisburg is the central core neighborhood, business and government center which surrounds the focal point of Market Square, and serves as the regional center for the greater metropolitan area of Harrisburg, Pennsylvania, United States. ...

. The section of US 322 between State College and Harrisburg serves as a major access road to Pennsylvania State University from points to the southeast and experiences traffic congestion on

Penn State Nittany Lions football The Penn State Nittany Lions team represents the Pennsylvania State University in college football. The Nittany Lions compete in the NCAA Division I Football Bowl Subdivision as a member of the Big Ten Conference, which they joined in 1993 afte ...

home game days.

Harrisburg to New Jersey

US 322 heads east along with I-81 on a six-lane freeway that is part of the

Capital Beltway The Capital Beltway is a Interstate Highway in the Washington metropolitan area that surrounds Washington, D.C., the capital of the United States, and its inner suburbs in adjacent Maryland and Virginia. It is the basis of the phrase "inside th ...

that circles Harrisburg. The freeway leaves the city limits of Harrisburg and runs through suburban areas. I-81/US 322 comes to a partial cloverleaf interchange with Progress Avenue before reaching a directional T interchange with the northern terminus of

I-83 Interstate 83 (I-83) is an Interstate Highway in the Eastern United States. Its southern terminus is at a signalized intersection with Fayette Street in Baltimore, Maryland; its northern terminus is at I-81 near Harrisburg, Pennsylvania. Most ...

. At this point, US 322 and the Capital Beltway split from I-81 by heading south along I-83. The four-lane freeway runs south-southeast to the east of Harrisburg, coming to a partial cloverleaf interchange with US 22 that serves the communities of

Progress Progress is the movement towards a refined, improved, or otherwise desired state. In the context of progressivism, it refers to the proposition that advancements in technology, science, and social organization have resulted, and by extension wi ...

to the west and Colonial Park to the east. Past here, I-83/US 322 reaches a diamond interchange with Union Deposit Road. Farther south, US 322 splits from I-83 at a eastbound exit and westbound entrance and heads south along four-lane divided Eisenhower Boulevard, immediately coming to a partial cloverleaf interchange with Derry Street. The road passes under Norfolk Southern's

Harrisburg Line The Harrisburg Line is a rail line owned and operated by the Norfolk Southern Railway (NS) in the U.S. state of Pennsylvania. The line runs from Philadelphia west to Harrisburg. The Harrisburg Line was formed the day Conrail began operations, A ...

and reaches the Eisenhower Interchange with connections to I-83, the northern terminus of I-283, and Paxton Street, where US 322 splits from Eisenhower Boulevard to head east along a four-lane freeway. The freeway heads near suburban areas with some industrial development and comes to an interchange with Penhar Drive. Past this interchange, the freeway ends and US 322 continues east as a four-lane divided highway. Farther east, the route becomes Paxton Street and it runs east. The road turns into an unnamed freeway and crosses the

Swatara Creek Swatara Creek (nicknamed the Swatty) is a U.S. Geological Survey. National Hydrography Dataset high-resolution flowline dataThe National Map accessed August 8, 2011 tributary of the Susquehanna River in east-central Pennsylvania in the United Sta ...

, bypassing the borough of

Hummelstown Hummelstown is a borough in Dauphin County, Pennsylvania, United States. The population was 4,535 as of the 2020 census. It is part of the Harrisburg–Carlisle Metropolitan Statistical Area. Originally named Fredrickstown, the town was establi ...

to the south. The freeway runs along the southern border of Hummelstown and passes between developed areas of the borough to the north and rural areas to the south, crossing the

Middletown and Hummelstown Railroad The Middletown and Hummelstown Railroad is a shortline railroad which operates freight train, freight and Heritage railway, tourist passenger trains between Middletown, Dauphin County, Pennsylvania, Middletown to Hummelstown, Pennsylvania. Passe ...

at-grade. While bypassing Hummelstown, US 322 comes to a eastbound exit and westbound entrance with South Hanover Street/Middletown Road and a westbound exit and eastbound entrance with Quarry Road/Waltonville Road; a two-lane undivided

frontage road A frontage road (also known as an access road, outer road, service road, feeder road, or parallel road) is a local road running parallel to a higher-speed, limited-access road. A frontage road is often used to provide access to private drivew ...

to the south of US 322 connects these two interchanges. From here, the freeway curves northeast and leaves Hummelstown, reaching a partial cloverleaf interchange with the western terminus of the eastern segment of

US 422 U.S. Route 422 (US 422) is a long spur route of US 22 split into two segments in the U.S. states of Ohio and Pennsylvania. The western segment of US 422 runs from downtown Cleveland, Ohio, east to Ebensburg, Pennsylvania. ...

and the eastern terminus of PA 39. At this point, the freeway continues as US 422, which soon becomes an at-grade divided highway, while US 322 exits to continue east along West Governor Road, a three-lane road with a center left-turn lane. The road heads into the southern part of the community of Hershey and runs through developed areas, passing to the north of

Penn State Milton S. Hershey Medical Center Penn State Health Milton S. Hershey Medical Center (MSHMC) is a 628-bed non-profit, tertiary, research and academic medical center located in Hershey, Pennsylvania, servicing the Central Pennsylvania area. MSHMC is the region's only university-le ...

and Penn State Health Children's Hospital. The route narrows to two lanes before intersecting PA 743. US 322 becomes East Governor Road and heads between Hershey High School to the north and farmland to the south before passing through the campus of the

Milton Hershey School The Milton Hershey School, formerly the Hershey Industrial School, is a private boarding school in Hershey, Pennsylvania for K–12 students. The institution was founded in 1909 by chocolate industrialist Milton Hershey and his wife, Catherine ...

, coming to roundabouts at Homestead Lane and Meadow Lane serving the school. The road leaves Hershey and runs through agricultural areas in the

Lebanon Valley The Lebanon Valley is a geographic region that lies between South Mountain and the Ridge and Valley Province of eastern Pennsylvania. The valley lies almost entirely within Lebanon and Berks counties in Pennsylvania. Portions of the valley lie ...

. US 322 enters

Lebanon County Lebanon County ( Pennsylvania Dutch: Lebanon Kaundi) is a county in the Commonwealth of Pennsylvania. As of the 2010 census, the population was 133,568. Its county seat is the city of Lebanon. The county was formed from portions of Dauphin ...

and becomes Horseshoe Pike, where it heads into the community of Campbelltown. On the eastern edge of Campbelltown, the route crosses

PA 117 Pennsylvania Route 117 (PA 117) is a state route in Lebanon County, Pennsylvania, Lebanon County, Pennsylvania. Its southern terminus is at an interchange with U.S. Route 322 in Pennsylvania, U.S. Route 322 (US 322)/Pennsylvania Route 72, PA 72 i ...

. From here, the road passes through the communities of Mount Pleasant and

Fontana Fontana may refer to: Places Italy *Fontana Liri, comune in the Province of Frosinone *Fontanafredda, comune in the Province of Pordenone *Fontanarosa, comune in the Province of Avellino *Francavilla Fontana, comune in the Province of Brindisi * ...

. US 322 comes to a junction with PA 241, where that route turns east to join US 322 in a concurrency. A short distance later, the road has an intersection with the southern terminus of PA 934. The two routes continue east, with PA 241 splitting from US 322 by turning to the north. US 322 has a junction with the southern terminus of PA 419 west of the community of

Quentin Quentin is a French male given name from the Latin first name ''Quintinus'', diminutive form of ''Quintus (praenomen), Quintus'', that means "the fifth".Albert Dauzat, ''Noms et prénoms de France'', Librairie Larousse 1980, édition revue et com ...

, where it curves to the southeast. The route turns into a freeway as it reaches a westbound exit and eastbound entrance with PA 72, where PA 72 becomes concurrent with US 322. The four-lane freeway enters the borough of

Cornwall Cornwall (; kw, Kernow ) is a historic county and ceremonial county in South West England. It is recognised as one of the Celtic nations, and is the homeland of the Cornish people. Cornwall is bordered to the north and west by the Atlantic ...

and comes to an interchange with the southern terminus of PA 117, passing over the

Lebanon Valley Rail Trail The Lebanon Valley Rail Trail (LVRT) is a National Recreation Trail. The rail trail goes from the southwestern border of Lebanon County and goes through Colebrook, Mt. Gretna, Cornwall, and the city of Lebanon. At the southern border of Lebanon ...

at this interchange. The freeway runs through rural areas, with PA 72 splitting at an interchange to head south. US 322 heads east as a two-lane undivided expressway as it traverses South Mountain. Farther east, the expressway ends and the route becomes two-lane undivided 28th Division Highway, curving southeast and leaving Cornwall. US 322 WB past PA 23

US 322 enters Lancaster County and continues east across the mountain along West 28th Division Highway, turning to the southeast. After crossing South Mountain, the road passes over the

Pennsylvania Turnpike The Pennsylvania Turnpike (Penna Turnpike or PA Turnpike) is a toll highway operated by the Pennsylvania Turnpike Commission (PTC) in the U.S. state of Pennsylvania. A controlled-access highway, it runs for across the state. The turnpike's we ...

(

I-76 Interstate 76 may refer to: Interstate Highways in the United States * Interstate 76 (Colorado–Nebraska) * Interstate 76 (Ohio–New Jersey), running through Pennsylvania Video gaming * ''Interstate '76 ''Interstate '76'' is a vehicular c ...

) and runs through a mix of rural areas and development, intersecting PA 501 in the community of Brickerville. The route becomes East 28th Division Highway and continues east, crossing Middle Creek. At this point, the road name changes to West Main Street and it passes through the community of

Clay Clay is a type of fine-grained natural soil material containing clay minerals (hydrous aluminium phyllosilicates, e.g. kaolin, Al2 Si2 O5( OH)4). Clays develop plasticity when wet, due to a molecular film of water surrounding the clay par ...

. US 322 runs east-southeast and runs through the community of Weidmanville before it enters the borough of

Ephrata Ephrata may refer to: Places * Ephrata, Suriname * Ephrata, Pennsylvania, U.S. *Ephrata, Washington, U.S. * Ephrata Township, Pennsylvania, U.S. Other uses *Ephrata Cloister, a religious community in Ephrata, Pennsylvania See also * * Efrata or E ...

. At this point, the route heads into developed areas and continues southeast to a cloverleaf interchange with PA 272, where it widens to four lanes. Past this interchange, the road narrows back to two lanes and passes northeast of the

Ephrata Cloister The Ephrata Cloister or Ephrata Community was a Intentional community, religious community, established in 1732 by Conrad Beissel, Johann Conrad Beissel at Ephrata, Pennsylvania, Ephrata, in what is now Lancaster County, Pennsylvania, Lancaster ...

before crossing

Cocalico Creek Cocalico Creek is a U.S. Geological Survey. National Hydrography Dataset high-resolution flowline dataThe National Map, accessed August 8, 2011 tributary of the Conestoga River in Lebanon County, Pennsylvania, Lebanon and Lancaster County, Pennsyl ...

. US 322 continues southeast into the downtown area of Ephrata and becomes East Main Street upon crossing State Street. A short distance later, the road meets the terminus of the Warwick to Ephrata Rail Trail. The route leaves the downtown area and continues southeast, crossing out of the borough limits of Ephrata and running east-southeast past more development. US 322 widens into a four-lane divided highway and comes to a

diverging diamond interchange A diverging diamond interchange (DDI), also called a double crossover diamond interchange (DCD), is a subset of diamond interchange in which the opposing directions of travel on the non-freeway road cross each other on either side of the inte ...

with the US 222 freeway. Following the US 222 interchange, the road becomes two-lane undivided Division Highway continues southeastward through the

Pennsylvania Dutch Country The Pennsylvania Dutch Country (Pennsylvania Dutch: ''Deitscherei'' Dutchery', also called Pennsylvania Dutchland (Pennsylvania Dutch: ''Pennsylvania Deitschland'', german: Pennsylvania Deutschland), or simply the Dutch Country or Dutchland (Pen ...

of eastern Lancaster County, which is home to many

Amish The Amish (; pdc, Amisch; german: link=no, Amische), formally the Old Order Amish, are a group of traditionalist Anabaptist Christian church fellowships with Swiss German and Alsatian origins. They are closely related to Mennonite churches ...

farms. The route crosses the

Conestoga River The Conestoga River, also referred to as Conestoga Creek, is a U.S. Geological Survey. National Hydrography Dataset high-resolution flowline dataThe National Map, accessed August 8, 2011 tributary of the Susquehanna River flowing through the cente ...

and passes through the community of Hinkletown. Farther southeast, US 322 runs through the community of Reidenbach before it reaches the community of

Blue Ball Blue is one of the three primary colours in the RYB colour model (traditional colour theory), as well as in the RGB (additive) colour model. It lies between violet and cyan on the spectrum of visible light. The eye perceives blue when obse ...

, where it has an intersection with PA 23. The road runs near some development and forms a short concurrency with PA 897. From here, the route continues east through agricultural areas, passing through the communities of Fetterville and Beartown. At this point, US 322 travels east-southeast across Welsh Mountain. US 322 WB past US 30

US 322 enters

Chester County Chester County may refer to: * Chester County, Pennsylvania, United States * Chester County, South Carolina, United States * Chester County, Tennessee, United States * Cheshire or the County Palatine of Chester, a ceremonial county in the North Wes ...

and becomes Horseshoe Pike, continuing southeast through rural areas to the borough of Honey Brook. At this point, the route runs southeast through the borough, where it intersects PA 10. Upon leaving Honey Brook, the road continues through rural areas with increasing development, crossing the

West Branch Brandywine Creek The West Branch Brandywine Creek is a U.S. Geological Survey. National Hydrography Dataset high-resolution flowline dataThe National Map accessed April 1, 2011 tributary of Brandywine Creek in Chester County, Pennsylvania in the United States.Ger ...

. Farther southeast, US 322 reaches an intersection with PA 82 in the community of Brandywine Manor. From here, the route runs southeast through suburban areas with some rural land, passing through the communities of Little Washington and Guthriesville. The road comes to a partial cloverleaf interchange with the

US 30 U.S. Route 30 or U.S. Highway 30 (US 30) is an east–west main route in the system of the United States Numbered Highways, with the highway traveling across the northern tier of the country. With a length of , it is the third longest ...

freeway, where it briefly becomes a divided highway. Past this interchange, US 322 passes north of a

park and ride A park and ride, also known as incentive parking or a commuter lot, is a parking lot with public transport connections that allows commuting, commuters and other people heading to city centres to leave their vehicles and transfer to a bus, Rail t ...

lot and becomes Manor Avenue, a three-lane road with a center left-turn lane that enters the borough of Downingtown. Here, the route passes through developed areas, heading to the south of

Downingtown West High School Downingtown High School is a secondary school located in Downingtown, Pennsylvania and Uwchlan Township, Pennsylvania. Population growth in the burgeoning Downingtown Area School District forced the original Downingtown High School to split into ...

, and narrows to two lanes before coming to an intersection with US 30 Bus. At this point, US 322 turns northeast for a concurrency with US 30 Bus. on West Lancaster Avenue, crossing the

East Branch Brandywine Creek The East Branch Brandywine CreekMouth: 39 55'21"N, 75 38'58"W, elevation: 174 ft.; Source: 40 07'09"N,75 53'15"W, is a U.S. Geological Survey. National Hydrography Dataset high-resolution flowline dataThe National Map , accessed April 1, 2011 tr ...

and heading in the downtown area of Downingtown on East Lancaster Avenue. US 322 splits from US 30 Bus. by turning south onto Brandywine Avenue, with US 322 Truck heading east along with US 30 Bus. The route passes under

Amtrak The National Railroad Passenger Corporation, Trade name, doing business as Amtrak () , is the national Passenger train, passenger railroad company of the United States. It operates inter-city rail service in 46 of the 48 contiguous United Stat ...

Keystone Corridor The Keystone Corridor is a 349-mile (562 km) railroad corridor between Philadelphia and Pittsburgh, Pennsylvania, that consists of two rail lines: Amtrak and SEPTA's Philadelphia-to-Harrisburg main line, which hosts SEPTA's Paoli/Thorndale ...

railroad line and intersects the other end of US 322 Truck at Boot Road along the southern border of Downingtown. From here, the road curves southeast and passes over the East Branch Brandywine Creek and under an abandoned railroad line. At this point, US 322 becomes Downingtown Pike and runs parallel to the creek through a mix of rural and suburban areas. The route turns east and crosses the creek, at which point the East Branch Brandywine Creek turns south away from the road. US 322 widens to four lanes and turns east onto the two-lane undivided West Chester Bypass, with US 322 Bus. continuing southeast along Downingtown Pike toward the borough of West Chester. The route follows the bypass east-northeast through suburban areas to the north of West Chester, coming to a westbound exit to northbound Pottstown Pike and eastbound entrance from southbound Pottstown Pike. The road continues northeast and curves east, passing under an abandoned railroad line before merging into the southbound direction of the

US 202 U.S. Route 202 (US 202) is a spur route of US 2. It follows a northeasterly and southwesterly direction stretching from Delaware to Maine, also traveling through the states of Pennsylvania, New Jersey, New York, Connecticut, Mass ...

freeway at a partial interchange. US 202/US 322 continue south-southeast along the West Chester Bypass as a four-lane freeway bypassing West Chester to the east, coming to a partial cloverleaf interchange with Paoli Pike. A short distance later, the two routes reach a partial cloverleaf interchange with PA 3. The freeway continues south to a diamond interchange at Westtown Road before it curves southwest, passing over the

West Chester Railroad The West Chester Railroad is a privately owned and operated tourist railroad that runs between Market Street in West Chester, Pennsylvania, in Chester County, and the village of Glen Mills, Pennsylvania, in Delaware County. It operates on of ...

before coming to an at-grade intersection with South Matlack Street. Following this, the bypass continues to its terminus at a trumpet interchange with the eastern terminus of US 322 Bus., which heads north (west) into West Chester on South High Street. At this point, US 202/US 322 exit and head southeast along four-lane divided Wilmington Pike, passing through suburban areas. The road comes to a

jughandle A jughandle is a type of ramp or slip road that changes the way traffic turns left at an at-grade intersection (in a country where traffic drives on the right). Instead of a standard left turn being made from the left lane, left-turning traffic ...

-controlled intersection at Stetson Middle School Drive/Skiles Boulevard before it crosses PA 926 in the community of Darlington Corners. US 322 WB past Evergreen Drive Concordville

US 322 WB past Evergreen Drive Concordville

US 202/US 322 crosses into Delaware County and continues southeast along Wilmington-West Chester Pike, coming to an intersection with Oakland Road that has an eastbound jughandle. The road comes to the community of Painters Crossing and reaches an intersection with

US 1 U.S. Route 1 or U.S. Highway 1 (US 1) is a major north–south United States Numbered Highway that serves the East Coast of the United States. It runs from Key West, Florida, north to Fort Kent, Maine, at the Canadian border, making i ...

, where US 322 splits from US 202 by heading east along with US 1 on four-lane divided

Baltimore Pike The Baltimore Pike was an auto trail connecting Baltimore, Maryland, with Philadelphia, Pennsylvania. Today, parts of the road are signed as U.S. Route 1 (US 1), US 13, and a small portion of Pennsylvania Route 41 (PA 41). A section of the road ...

. The road continues east to the community of Concordville, where US 322 splits from US 1 by heading southeast along Conchester Highway, a four-lane divided highway. The route runs through suburban areas, passing over Smithbridge Road and narrowing to a two-lane undivided road before coming to an interchange with the northern terminus of PA 261. The road continues east and passes over Chichester Avenue before it widens into a four-lane divided highway and reaches an interchange with PA 452. Farther east, US 322 passes over

CSX CSX Transportation , known colloquially as simply CSX, is a Class I freight railroad operating in the Eastern United States and the Canadian provinces of Ontario and Quebec. The railroad operates approximately 21,000 route miles () of track. ...

Philadelphia Subdivision The Philadelphia Subdivision is a railroad line owned and operated by CSX Transportation in the U.S. states of Pennsylvania, Delaware, and Maryland. The line runs from Philadelphia, Pennsylvania, southwest to Baltimore, Maryland, along a forme ...

railroad line and comes to an interchange with Bethel Road. The route passes north of CSX's Twin Oaks Rail Yard, an automotive unloading facility, before it comes to an interchange with

I-95 Interstate 95 (I-95) is the main north–south Interstate Highway on the East Coast of the United States, running from US Route 1 (US 1) in Miami, Florida, to the Houlton–Woodstock Border Crossing between Maine and the Canadia ...

and Highland Avenue. At this interchange, US 322 merges onto northbound I-95; this interchange consists of full access between US 322 and Highland Avenue and partial access between US 322 and I-95. At this point, US 322 joins I-95 on the Delaware Expressway, a seven-lane freeway with four northbound lanes and three southbound lanes and enters the city of

, passing through urban areas. The freeway leaves the city limits and US 322 splits from I-95 to head southeast on a freeway at a directional T interchange; this interchange includes a ramp from westbound US 322 to Concord Road. The route crosses back into Chester as it follows a five-lane freeway with three eastbound lanes and two westbound lanes that is maintained by the

Delaware River Port Authority The Delaware River Port Authority (DRPA), officially the Delaware River Port Authority of Pennsylvania and New Jersey, is a bi-state agency instrumentality created by a congressionally approved interstate compact between the governments of Penn ...

. The freeway comes to a westbound exit and eastbound entrance with US 13 Bus. before it passes over Amtrak's

Northeast Corridor The Northeast Corridor (NEC) is an electrified railroad line in the Northeast megalopolis of the United States. Owned primarily by Amtrak, it runs from Boston through Providence, New Haven, Stamford, New York City, Philadelphia, Wilmington, a ...

railroad line and reaches an eastbound exit and westbound entrance with

US 13 U.S. Route 13 (US 13) is a north–south U.S. highway established in 1926 that runs for from Interstate 95 (I-95) just north of Fayetteville, North Carolina to US 1 in the northeastern suburbs of Philadelphia, Pennsylvania, in Morrisville. ...

/ PA 291. At this point, US 322 heads onto the

, passing over

Conrail Shared Assets Operations Conrail Shared Assets Operations (CSAO) is the commonly used name for modern-day Conrail (reporting mark CRCX), an American railroad company. It operates three networks, the North Jersey, South Jersey/Philadelphia, and Detroit Shared Assets Area ...

Chester Industrial Track The Chester Secondary is an active railroad line in the U.S. states of Pennsylvania and Delaware. The line is operated by Conrail Shared Assets Operations, which serves as contract local carrier and switching company for both CSX Transportation and ...

line and running to the northeast of

Subaru Park Subaru Park (formerly known as PPL Park and Talen Energy Stadium) is a soccer-specific stadium located in Chester, Pennsylvania, located next to the Commodore Barry Bridge on the waterfront along the Delaware River. The venue is home to the Phila ...

, the home stadium of the

Philadelphia Union The Philadelphia Union are an American professional soccer club based in Chester, Pennsylvania. The Union compete in Major League Soccer (MLS) as a member of the Eastern Conference. Founded on February 28, 2008, the club began playing in 201 ...

Major League Soccer Major League Soccer (MLS) is a men's professional soccer league sanctioned by the United States Soccer Federation, which represents the sport's highest level in the United States. The league comprises 29 teams—26 in the U.S. and 3 in Canada ...

, before it crosses the

into

History

The earliest predecessors of US 322 were several

turnpike Turnpike often refers to: * A type of gate, another word for a turnstile * In the United States, a toll road Turnpike may also refer to: Roads United Kingdom * A turnpike road, a principal road maintained by a turnpike trust, a body with powers ...

s. The Downingstown, Ephrata, and Harrisburg Turnpike was chartered in 1803, forming the bulk of the highway east of Harrisburg. A brief section from Philipsburg to West Decatur was part of the Philipsburg and Susquehanna Turnpike, with a western terminus at

Curwensville Curwensville is a borough in Clearfield County, Pennsylvania, United States, north of Altoona on the West Branch Susquehanna River. Coal mining, tanning, and the manufacture of fire bricks were the industries at the turn of the 20th century. In 1 ...

. From there to Meadville, the highway was the Susquehanna and Waterford Turnpike, which extended north to Waterford. The latter two turnpikes were part of the cross-state route known as the Northumberland and Waterford Turnpike. These highways were mostly incorporated into the

Lakes-to-Sea Highway The Lakes-to-Sea Highway, also known as the "Ship-to-Shore" highway, was an auto trail in the Northeast U.S., running from Erie, Pennsylvania (on Lake Erie) southeast via Harrisburg and Philadelphia to Atlantic City, New Jersey (on the Atlantic Oce ...

, which went from

Erie Erie (; ) is a city on the south shore of Lake Erie and the county seat of Erie County, Pennsylvania, United States. Erie is the fifth largest city in Pennsylvania and the largest city in Northwestern Pennsylvania with a population of 94,831 a ...

east to

. This route deviated from the early turnpikes in central Pennsylvania, by swinging south from DuBois along US 219 to service Grampain, then north on PA 879 to service Clearfield. From Philipsburg, it followed PA 53 to Osceola Mills and State Street and PA 350 to

Bald Eagle The bald eagle (''Haliaeetus leucocephalus'') is a bird of prey found in North America. A sea eagle, it has two known subspecies and forms a species pair with the white-tailed eagle (''Haliaeetus albicilla''), which occupies the same niche as ...

. It then went south along South Bald Eagle Road (at the time also

) to Tyrone, then PA 453 and PA 45 meet US 22 at Water Street. The two highways bore a concurrency to Harrisburg. At the time of their marking, both highways swung north from Mill Creek, following PA 655 to Reedsville, then south to Lewistown, where they resumed the modern alignment. From West Chester, the highway followed PA 3 to Philadelphia. This highway was numbered as PA 5 in the earliest numbering system in the state. US 322, in its original inception, followed PA 5 from Water Street to Meadville, where it continued west on its modern alignment. Both US 22 and US 322 followed their modern alignments east of Lewistown. In 1928, concurrencies with this highway and its PA 5 moniker were deleted in favor of the national number. In 1937, US 322 was extended to and through New Jersey, replacing what remained of PA 5 between Harrisburg and West Chester, and PA 61 to Chester. In 1957, US 322 was routed onto a limited-access bypass of West Chester to the north and east. As a result, US 322 Bus. replaced the US 322 designation through West Chester. In 1970, the highway was rerouted to bypass Curwensville to the north, replacing a section of PA 410. In December 2007, construction to convert the section of US 22/US 322 through the Lewistown Narrows from a two-lane highway to a divided, limited-access four-lane highway was completed. 2022-09-05 09 43 13 will rename and categorize soon 016

2022-09-05 09 43 13 will rename and categorize soon 016

To decrease congestion and improve safety, the

Pennsylvania Department of Transportation The Pennsylvania Department of Transportation (PennDOT) oversees transportation issues in the Commonwealth of Pennsylvania. The administrator of PennDOT is the Pennsylvania Secretary of Transportation, currently Yassmin Gramian. Presently, Pe ...

(PennDOT) began a project in 2014 to reconstruct US 322 from the

Centre Center or centre may refer to: Mathematics *Center (geometry), the middle of an object * Center (algebra), used in various contexts ** Center (group theory) ** Center (ring theory) * Graph center, the set of all vertices of minimum eccentricity ...

/ Mifflin county line to the route's interchange with

, at a cost of about $93 million. On March 30, 2018, the Sand Mountain Road interchange opened, replacing the at-grade intersection. The bulk of the cost of the project is related to an extension of the four-lane portion of US 322 through Potters Mills Gap and a new interchange with PA 144, which opened on October 10, 2020. The section of US 322 along Conchester Highway between US 1 in Concordville and I-95 in Chester opened in 1954. PennDOT had plans since 1979 to widen the stretch of US 322 along Conchester Highway from a two-lane road to a four-lane road. The stretch of road saw a large number of accidents and fatalities, leading to the nickname "Killer Conchester". Construction on the project to widen the Conchester Highway section of US 322 began on April 28, 2017, with Governor

Tom Wolf Thomas Westerman Wolf (born November 17, 1948) is an American politician and businessman serving as the 47th governor of Pennsylvania since 2015. A member of the Democratic Party, he defeated Republican incumbent Tom Corbett in the 2014 guber ...

, PennDOT secretary

Leslie Richards Leslie Richards (born April 3, 1967) is the current General Manager of SEPTA, the public transportation agency serving the Philadelphia area. She previously served as a member of the Montgomery County Board of Commissioners and as Secretary of th ...

, and other state and local officials in attendance for a groundbreaking ceremony. Construction on the first phase of the widening between US 1 and Clayton Park Drive started in 2017 and was completed in December 2020. Plans to widen US 322 between Clayton Park Drive and east of Chelsea Parkway/Bethel Avenue are in the final design phase, with construction to begin in 2025. Plans to reconstruct the four-lane section of US 322 from Cherry Tree Road/Bethel Avenue to east of PA 452 are in the final design phase, with construction to begin in 2023. Plans to replace the bridge over the CSX tracks and Bethel Road along with improving the Bethel Road interchange are in the final design phase, with construction to begin in 2023. In 2019, construction began to convert the interchange with US 222 near Ephrata into a diverging diamond interchange. The diverging diamond interchange, which cost $10.9 million and received federal funding, opened on May 17, 2021, one year ahead of schedule.

Major intersections

References

External links