Damiana
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Damiana
''Turnera diffusa'', known as damiana, is a shrub native to southern Texas in the United States, Central America, Mexico, South America, and the Caribbean. It belongs to the family Passifloraceae. Damiana is a relatively small, woody shrub that produces small, aromatic flowers. It blossoms in early to late summer and is followed by fruits that taste similar to figs. The shrub is said to have a strong spice-like odor somewhat like chamomile, due to the essential oils present in the plant. Uses Damiana is an ingredient in a traditional Mexican liqueur, which is sometimes used in lieu of triple sec in margaritas. Mexican folklore claims that it was used in the "original" margarita. The damiana margarita is popular in the Los Cabos region of Mexico. Damiana was included in several 19th-century patent medicines, such as Pemberton's French Wine Coca. The leaves were omitted from that product's non-alcoholic counterpart, Coca-Cola. In folklore, the plant was believed to be an aphr ...
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Acacetin
Acacetin is a 4′- ''O''-methylated flavone of the parent compound apigenin, found in ''Robinia pseudoacacia ''Robinia pseudoacacia'', commonly known in its native territory as black locust, is a medium-sized hardwood deciduous tree, belonging to the tribe Robinieae of the legume family Fabaceae. It is endemic to a few small areas of the United Sta ...'' (black locust), '' Turnera diffusa'' (damiana), shows moderate aromatase inhibition, '' Betula pendula'' (silver birch), and in the fern '' Asplenium normale''. In plant synthesis the enzyme apigenin 4′-''O''-methyltransferase uses ''S''-adenosyl methionine and 5,7,4′-trihydroxyflavone (apigenin) to produce ''S''-adenosylhomocysteine and 4′-methoxy-5,7-dihydroxyflavone (acacetin). See also * Genkwanin (methoxylated apigenin) * Thevetiaflavone (methoxylated apigenin) References Aromatase inhibitors O-methylated flavones {{aromatic-stub ...
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1,8-cineole
Eucalyptol is a monoterpenoid. A colorless liquid, it is a bicyclic ether. Eucalyptol has a fresh mint-like smell and a spicy, cooling taste. It is insoluble in water, but miscible with organic solvents. Eucalyptol makes up ~70% - 90% of eucalyptus oil. Eucalyptol forms crystalline adducts with hydrohalic acids, ''o''-cresol, resorcinol, and phosphoric acid. Formation of these adducts is useful for purification. In 1870, F. S. Cloez identified and ascribed the name "eucalyptol" to the dominant portion of '' Eucalyptus globulus'' oil. Uses Because of its pleasant, spicy aroma and taste, eucalyptol is used in flavorings, fragrances, and cosmetics. Cineole-based eucalyptus oil is used as a flavouring at low levels (0.002%) in various products, including baked goods, confectionery, meat products, and beverages. In a 1994 report released by five top cigarette companies, eucalyptol was listed as one of the 599 additives to cigarettes. It is claimed to be added to improve t ...
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Pemberton's French Wine Coca
Pemberton's French Wine Coca was a coca wine created by the druggist John Pemberton, the inventor of Coca-Cola. It was an alcoholic beverage, mixed with coca, kola nut, and damiana. The original recipe contained the ingredient cocaethylene (cocaine mixed with alcohol), which was removed, just like the alcohol had before it, in 1899 because of a social stigma surrounding the rampant use of cocaine at the time. History French wine coca is a combination of cocaethylene (a unique drug made by mixing cocaine and alcohol) and French wine. In 1863, a Parisian chemist Angelo Mariani combined coca and wine and started selling it under the name " Vin Mariani". This became extremely popular. Jules Verne, Alexander Dumas, and Arthur Conan Doyle were among literary figures said to have used it, and the chief rabbi of France is quoted to have said, "Praise be to Mariani's wine!" Pope Leo XIII reportedly carried a flask of it regularly and gave Mariani a medal. Seeing this commercial su ...
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Coca-Cola
Coca-Cola, or Coke, is a carbonated soft drink manufactured by the Coca-Cola Company. Originally marketed as a temperance drink and intended as a patent medicine, it was invented in the late 19th century by John Stith Pemberton in Atlanta, Georgia. In 1888, Pemberton sold Coca-Cola's ownership rights to Asa Griggs Candler, a businessman, whose marketing tactics led Coca-Cola to its dominance of the global soft-drink market throughout the 20th and 21st century. The drink's name refers to two of its original ingredients: coca leaves and kola nuts (a source of caffeine). The current formula of Coca-Cola remains a closely guarded trade secret; however, a variety of reported recipes and experimental recreations have been published. The secrecy around the formula has been used by Coca-Cola in its marketing as only a handful of anonymous employees know the formula. The drink has inspired imitators and created a whole classification of soft drink: colas. The Coca-Cola Company p ...
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Flavonoid
Flavonoids (or bioflavonoids; from the Latin word ''flavus'', meaning yellow, their color in nature) are a class of polyphenolic secondary metabolites found in plants, and thus commonly consumed in the diets of humans. Chemically, flavonoids have the general structure of a 15-carbon skeleton, which consists of two phenyl rings (A and B) and a heterocyclic ring (C, the ring containing the embedded oxygen). This carbon structure can be abbreviated C6-C3-C6. According to the IUPAC nomenclature, they can be classified into: *flavonoids or bioflavonoids * isoflavonoids, derived from 3-phenyl chromen-4-one (3-phenyl-1,4- benzopyrone) structure *neoflavonoids, derived from 4-phenyl coumarine (4-phenyl-1,2- benzopyrone) structure The three flavonoid classes above are all ketone-containing compounds and as such, anthoxanthins (flavones and flavonols). This class was the first to be termed bioflavonoids. The terms flavonoid and bioflavonoid have also been more loosely used to descri ...
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Thymol
Thymol (also known as 2-isopropyl-5-methylphenol, IPMP), , is a natural monoterpenoid phenol derivative of ''p''-Cymene, isomeric with carvacrol, found in oil of thyme, and extracted from ''Thymus vulgaris'' (common thyme), ajwain, and various other plants as a white crystalline substance of a pleasant aromatic odor and strong antiseptic properties. Thymol also provides the distinctive, strong flavor of the culinary herb thyme, also produced from ''T. vulgaris''. Thymol is only slightly soluble in water at neutral pH, but it is extremely soluble in alcohols and other organic solvents. It is also soluble in strongly alkaline aqueous solutions due to deprotonation of the phenol. Its dissociation constant ( p''K''a) is . Thymol absorbs maximum UV radiation at 274 nm. Chemical synthesis Thymol is produced by the alkylation of ''m''-cresol and propene: : History Ancient Egyptians used thyme for embalming. The ancient Greeks used it in their baths and burned it as ...
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Tannin
Tannins (or tannoids) are a class of astringent, polyphenolic biomolecules that bind to and precipitate proteins and various other organic compounds including amino acids and alkaloids. The term ''tannin'' (from Anglo-Norman ''tanner'', from Medieval Latin ''tannāre'', from ''tannum'', oak bark) refers to the use of oak and other bark in tanning animal hides into leather. By extension, the term ''tannin'' is widely applied to any large polyphenolic compound containing sufficient hydroxyls and other suitable groups (such as carboxyls) to form strong complexes with various macromolecules. The tannin compounds are widely distributed in many species of plants, where they play a role in protection from predation (acting as pesticides) and might help in regulating plant growth. The astringency from the tannins is what causes the dry and puckery feeling in the mouth following the consumption of unripened fruit, red wine or tea. Likewise, the destruction or modification of ...
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Alpha-Pinene
α-Pinene is an organic compound of the terpene class, one of two isomers of pinene. It is an alkene and it contains a reactive four-membered ring. It is found in the oils of many species of many coniferous trees, notably the pine. It is also found in the essential oil of rosemary (''Rosmarinus officinalis'') and '' Satureja myrtifolia'' (also known as ''Zoufa'' in some regions). Both enantiomers are known in nature; (1''S'',5''S'')- or (−)-α-pinene is more common in European pines, whereas the (1''R'',5''R'')- or (+)-α-isomer is more common in North America. The racemic mixture is present in some oils such as eucalyptus oil and orange peel oil. Reactivity : Commercially important derivatives of alpha-pinene are linalool, geraniol, nerol, a-terpineol, and camphene. α-Pinene 1 is reactive owing to the presence of the four-membered ring adjacent to the alkene. The compound is prone to skeletal rearrangements such as the Wagner–Meerwein rearrangement. Acids typ ...
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Apigenin
Apigenin (4′,5,7-trihydroxyflavone), found in many plants, is a natural product belonging to the flavone class that is the aglycone of several naturally occurring glycosides. It is a yellow crystalline solid that has been used to dye wool. Sources in nature Apigenin is found in many fruits and vegetables, but parsley, celery, celeriac, and chamomile tea are the most common sources. Apigenin is particularly abundant in the flowers of chamomile plants, constituting 68% of total flavonoids. Dried parsley can contain about 45  mg apigenin/gram of the herb, and dried chamomile flower about 3-5 mg/gram. The apigenin content of fresh parsley is reportedly 215.5 mg/100 grams, which is much higher than the next highest food source, green celery hearts providing 19.1 mg/100 grams. Biosynthesis Apigenin is biosynthetically derived from the general phenylpropanoid pathway and the flavone synthesis pathway. The phenylpropanoid pathway starts from the aromatic am ...
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