Acacetin is a 4′-
''O''-methylated flavone of the parent compound
apigenin, found in ''
Robinia pseudoacacia
''Robinia pseudoacacia'', commonly known in its native territory as black locust, is a medium-sized hardwood deciduous tree, belonging to the tribe Robinieae of the legume family Fabaceae. It is endemic to a few small areas of the United Sta ...
'' (black locust), ''
Turnera diffusa'' (damiana), shows moderate aromatase inhibition, ''
Betula pendula'' (silver birch), and in the fern ''
Asplenium normale''.
In plant synthesis the enzyme
apigenin 4′-''O''-methyltransferase uses
''S''-adenosyl methionine and
5,7,4′-trihydroxyflavone (apigenin) to produce
''S''-adenosylhomocysteine and 4′-methoxy-5,7-dihydroxyflavone (acacetin).
See also
*
Genkwanin (methoxylated apigenin)
*
Thevetiaflavone (methoxylated apigenin)
References
Aromatase inhibitors
O-methylated flavones
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