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Acacetin
Acacetin is a 4′- ''O''-methylated flavone of the parent compound apigenin, found in ''Robinia pseudoacacia'' (black locust), ''Turnera diffusa'' (damiana), shows moderate aromatase inhibition, ''Betula pendula'' (silver birch), and in the fern ''Asplenium normale''. In plant synthesis the enzyme apigenin 4′-''O''-methyltransferase uses ''S''-adenosyl methionine and 5,7,4′-trihydroxyflavone (apigenin) to produce ''S''-adenosylhomocysteine and 4′-methoxy-5,7-dihydroxyflavone (acacetin). See also * Genkwanin Genkwanin is an O-methylated flavone, a type of flavonoid. It can be found in the seeds of ''Alnus glutinosa'', and the leaves of the ferns ''Notholaena bryopoda'' and ''Asplenium normale'' and ''Aquilaria ''Aquilaria'' is a genus of fifteenNg ... (methoxylated apigenin) * Thevetiaflavone (methoxylated apigenin) References Aromatase inhibitors O-methylated flavones {{aromatic-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
O-methylated Flavonoid
The O-methylated flavonoids or methoxyflavonoids are flavonoids with methylations on hydroxyl groups ( methoxy bonds). O-methylation has an effect on the solubility of flavonoids. Enzymes O-methylated flavonoids formation implies the presence of specific O-methyltransferase (OMT) enzymes which accept a variety of substrates. Those enzymes mediate the O-methylation on a specific hydroxyl group, like on 4' (example in '' Catharanthus roseus'') or 3' (example in rice) positions. Those positions can be ortho, meta, para and there can be a special 3-O-methyltransferase for the 3-OH position. Calamondin orange ('' Citrus mitis'') exhibits all of those activities. Plant enzymes * Apigenin 4'-O-methyltransferase * 8-hydroxyquercetin 8-O-methyltransferase * Isoflavone 4'-O-methyltransferase * Isoflavone 7-O-methyltransferase * Isoliquiritigenin 2'-O-methyltransferase * Isoorientin 3'-O-methyltransferase * Kaempferol 4'-O-methyltransferase * Luteolin O-methyltransferase * Methylquercetage ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apigenin
Apigenin (4′,5,7-trihydroxyflavone), found in many plants, is a natural product belonging to the flavone class that is the aglycone of several naturally occurring glycosides. It is a yellow crystalline solid that has been used to dye wool. Sources in nature Apigenin is found in many fruits and vegetables, but parsley, celery, celeriac, and chamomile tea are the most common sources. Apigenin is particularly abundant in the flowers of chamomile plants, constituting 68% of total flavonoids. Dried parsley can contain about 45 mg apigenin/gram of the herb, and dried chamomile flower about 3-5 mg/gram. The apigenin content of fresh parsley is reportedly 215.5 mg/100 grams, which is much higher than the next highest food source, green celery hearts providing 19.1 mg/100 grams. Biosynthesis Apigenin is biosynthetically derived from the general phenylpropanoid pathway and the flavone synthesis pathway. The phenylpropanoid pathway starts from the aro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robinia Pseudoacacia
''Robinia pseudoacacia'', commonly known in its native territory as black locust, is a medium-sized hardwood deciduous tree, belonging to the tribe Robinieae of the legume family Fabaceae. It is endemic to a few small areas of the United States, but it has been widely planted and naturalized elsewhere in temperate North America, Europe, Southern Africa and Asia and is considered an invasive species in some areas. Another common name is false acacia, a literal translation of the specific name (''pseudo'' reek ''ψευδο-''meaning fake or false and ''acacia'' referring to the genus of plants with the same name). Description Black locust reaches a typical height of with a diameter of . It is a very upright tree with a straight trunk and narrow crown that grows scraggly with age. The dark blue-green compound leaves with a contrasting lighter underside give this tree a beautiful appearance in the wind and contribute to its grace. Black locust is a shade-intolerant species and t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Turnera Diffusa
''Turnera diffusa'', known as damiana, is a shrub native to southern Texas in the United States, Central America, Mexico, South America, and the Caribbean. It belongs to the family Passifloraceae. Damiana is a relatively small, woody shrub that produces small, aromatic flowers. It blossoms in early to late summer and is followed by fruits that taste similar to figs. The shrub is said to have a strong spice-like odor somewhat like chamomile, due to the essential oils present in the plant. Uses Damiana is an ingredient in a traditional Mexican liqueur, which is sometimes used in lieu of triple sec in margaritas. Mexican folklore claims that it was used in the "original" margarita. The damiana margarita is popular in the Los Cabos region of Mexico. Damiana was included in several 19th-century patent medicines, such as Pemberton's French Wine Coca. The leaves were omitted from that product's non-alcoholic counterpart, Coca-Cola. In folklore, the plant was believed to be an aph ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Betula Pendula
''Betula pendula'', commonly known as silver birch, warty birch, European white birch, or East Asian white birch, is a species of tree in the family Betulaceae, native to Europe and parts of Asia, though in southern Europe, it is only found at higher altitudes. Its range extends into Siberia, China, and southwest Asia in the mountains of northern Turkey, the Caucasus, and northern Iran. It has been introduced into North America, where it is known as the European white birch or weeping birch and is considered invasive in some states in the United States and parts of Canada. The tree can also be found in more temperate regions of Australia. The silver birch is a medium-sized deciduous tree that owes its common name to the white peeling bark on the trunk. The twigs are slender and often pendulous and the leaves are roughly triangular with doubly serrate margins and turn yellow and brown in autumn before they fall. The flowers are catkins and the light, winged seeds get widely s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Asplenium Normale
''Asplenium'' is a genus of about 700 species of ferns, often treated as the only genus in the family Aspleniaceae, though other authors consider '' Hymenasplenium'' separate, based on molecular phylogenetic analysis of DNA sequences, a different chromosome count, and structural differences in the rhizomes. The type species for the genus is ''Asplenium marinum''. The most common vernacular name is spleenworts, applied to the more "typical" species. '' A. nidus'' and several similar species are called bird's-nest ferns, the ''Camptosorus'' group is known as walking ferns, and distinct names are applied to some other particularly well-known species. Taxonomy and genetics Many groups of species have been separated from ''Asplenium'' as segregate genera. These include ''Camptosorus'', ''Ceterach'', ''Phyllitis'', and ''Tarachia'', but these species can form hybrids with other ''Asplenium'' species and because of this are usually included in a more broadly defined ''Asplenium' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apigenin 4'-O-methyltransferase
In enzymology, an apigenin 4'-O-methyltransferase () is an enzyme that catalyzes the chemical reaction :S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone \rightleftharpoons S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone Thus, the two substrates of this enzyme are S-adenosyl methionine and 5,7,4'-trihydroxyflavone (apigenin), whereas its two products are S-adenosylhomocysteine and 4'-methoxy-5,7-dihydroxyflavone (acacetin). This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:5,7,4'-trihydroxyflavone 4'-O-methyltransferase. Other names in common use include flavonoid O-methyltransferase, and flavonoid methyltransferase. This enzyme participates in flavonoid biosynthesis Flavonoids are synthesized by the phenylpropanoid metabolic pathway in which the amino acid phenylalanine is used to produce 4-coumaroyl-CoA. This can be combi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
S-Adenosyl Methionine
''S''-Adenosyl methionine (SAM), also known under the commercial names of SAMe, SAM-e, or AdoMet, is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. Although these anabolic reactions occur throughout the body, most SAM is produced and consumed in the liver. More than 40 methyl transfers from SAM are known, to various substrates such as nucleic acids, proteins, lipids and secondary metabolites. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase. SAM was first discovered by Giulio Cantoni in 1952. In bacteria, SAM is bound by the SAM riboswitch, which regulates genes involved in methionine or cysteine biosynthesis. In eukaryotic cells, SAM serves as a regulator of a variety of processes including DNA, tRNA, and rRNA methylation; immune response; amino acid metabolism; transsulfuration; and more. In plants, SAM is crucial to the biosynthesis of ethylene, an important plant hormone and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apigenin
Apigenin (4′,5,7-trihydroxyflavone), found in many plants, is a natural product belonging to the flavone class that is the aglycone of several naturally occurring glycosides. It is a yellow crystalline solid that has been used to dye wool. Sources in nature Apigenin is found in many fruits and vegetables, but parsley, celery, celeriac, and chamomile tea are the most common sources. Apigenin is particularly abundant in the flowers of chamomile plants, constituting 68% of total flavonoids. Dried parsley can contain about 45 mg apigenin/gram of the herb, and dried chamomile flower about 3-5 mg/gram. The apigenin content of fresh parsley is reportedly 215.5 mg/100 grams, which is much higher than the next highest food source, green celery hearts providing 19.1 mg/100 grams. Biosynthesis Apigenin is biosynthetically derived from the general phenylpropanoid pathway and the flavone synthesis pathway. The phenylpropanoid pathway starts from the aro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genkwanin
Genkwanin is an O-methylated flavone, a type of flavonoid. It can be found in the seeds of ''Alnus glutinosa'', and the leaves of the ferns '' Notholaena bryopoda'' and ''Asplenium normale ''Asplenium'' is a genus of about 700 species of ferns, often treated as the only genus in the family Aspleniaceae, though other authors consider '' Hymenasplenium'' separate, based on molecular phylogenetic analysis of DNA sequences, a diff ...'' and '' Aquilaria''. References O-methylated flavones {{aromatic-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
