''Turnera diffusa'', known as damiana, is a

shrub A shrub (often also called a bush) is a small-to-medium-sized perennial woody plant. Unlike herbaceous plants, shrubs have persistent woody stems above the ground. Shrubs can be either deciduous or evergreen. They are distinguished from trees ...

native to southern

Texas Texas (, ; Spanish language, Spanish: ''Texas'', ''Tejas'') is a state in the South Central United States, South Central region of the United States. At 268,596 square miles (695,662 km2), and with more than 29.1 million residents in 2 ...

in the United States, Central America, Mexico, South America, and the Caribbean. It belongs to the family

Passifloraceae The Passifloraceae are a family of flowering plants, containing about 750 species classified in around 27 genera. They include trees, shrubs, lianas, and climbing plants, and are mostly found in tropical regions. The family takes its name from ...

. Damiana is a relatively small, woody shrub that produces small, aromatic flowers. It blossoms in early to late summer and is followed by fruits that taste similar to figs. The shrub is said to have a strong spice-like odor somewhat like

chamomile Chamomile (American English) or camomile (British English; see spelling differences) ( or ) is the common name for several plants of the family Asteraceae. Two of the species, ''Matricaria recutita'' and ''Anthemis nobilis'', are commonly us ...

, due to the essential oils present in the plant.

Uses

Damiana is an ingredient in a traditional Mexican

liqueur A liqueur (; ; ) is an alcoholic drink composed of spirits (often rectified spirit) and additional flavorings such as sugar, fruits, herbs, and spices. Often served with or after dessert, they are typically heavily sweetened and un-aged beyond ...

, which is sometimes used in lieu of

triple sec Triple sec is an orange-flavoured liqueur that originated in France. It usually contains 20–40% alcohol by volume. Triple sec is rarely consumed neat, but is used in preparing many mixed drinks such as margaritas, cosmopolitans, sidecars, L ...

margarita A margarita is a cocktail consisting of Tequila, triple sec, and lime juice often served with salt on the rim of the glass. The drink is served shaken with ice (on the rocks), blended with ice (frozen margarita), or without ice (straight up). T ...

s. Mexican folklore claims that it was used in the "original" margarita. The damiana margarita is popular in the

Los Cabos LOS, or Los, or LoS may refer to: Science and technology * Length of stay, the duration of a single episode of hospitalisation * Level of service, a measure used by traffic engineers * Level of significance, a measure of statistical significance ...

region of Mexico.Damiana Liqueur at Damiana.net
/ref> Damiana was included in several 19th-century

patent medicine A patent medicine, sometimes called a proprietary medicine, is an over-the-counter (nonprescription) medicine or medicinal preparation that is typically protected and advertised by a trademark and trade name (and sometimes a patent) and claimed ...

s, such as

Pemberton's French Wine Coca Pemberton's French Wine Coca was a coca wine created by the druggist John Pemberton, the inventor of Coca-Cola. It was an alcoholic beverage, mixed with coca, kola nut, and damiana. The original recipe contained the ingredient cocaethylene (co ...

. The leaves were omitted from that product's non-alcoholic counterpart,

Coca-Cola Coca-Cola, or Coke, is a carbonated soft drink manufactured by the Coca-Cola Company. Originally marketed as a temperance drink and intended as a patent medicine, it was invented in the late 19th century by John Stith Pemberton in Atlanta ...

. In folklore, the plant was believed to be an aphrodisiac, hence its sometimes used binomial synonym, ''Turnera aphrodisiaca''.

Phytochemistry

Damiana contains damianin; tetraphyllin B; gonzalitosin I;

arbutin Arbutin is a glycoside; a glycosylated hydroquinone extracted from the bearberry plant in the genus ''Arctostaphylos'' among many other medicinal plants, primarily in the family Ericaceae. Applied topically, it inhibits tyrosinase and thus prev ...

; tricosan-2-one;

acacetin Acacetin is a 4′- ''O''-methylated flavone of the parent compound apigenin, found in ''Robinia pseudoacacia ''Robinia pseudoacacia'', commonly known in its native territory as black locust, is a medium-sized hardwood deciduous tree, belon ...

;

p-cymene ''p''-Cymene is a naturally occurring aromatic organic compound. It is classified as an alkylbenzene related to a monoterpene. Its structure consists of a benzene ring ''para''-substituted with a methyl group and an isopropyl group. ''p''-Cym ...

;

β-sitosterol β-sitosterol (beta-sitosterol) is one of several phytosterols (plant sterols) with chemical structures similar to that of cholesterol. It is a white, waxy powder with a characteristic odor, and is one of the components of the food additive E499 ...

; 1,8-cineole;

apigenin Apigenin (4′,5,7-trihydroxyflavone), found in many plants, is a natural product belonging to the flavone class that is the aglycone of several naturally occurring glycosides. It is a yellow crystalline solid that has been used to dye wool. S ...

;

α-pinene α-Pinene is an organic compound of the terpene class, one of two isomers of pinene. It is an alkene and it contains a reactive four-membered ring. It is found in the oils of many species of many coniferous trees, notably the pine. It is also ...

;

β-carotene β-Carotene is an organic, strongly coloured red-orange pigment abundant in fungi, plants, and fruits. It is a member of the carotenes, which are terpenoids (isoprenoids), synthesized biochemically from eight isoprene units and thus having 40 ...

; β-pinene;

tannin Tannins (or tannoids) are a class of astringent, polyphenolic biomolecules that bind to and precipitate proteins and various other organic compounds including amino acids and alkaloids. The term ''tannin'' (from Anglo-Norman ''tanner'', ...

thymol Thymol (also known as 2-isopropyl-5-methylphenol, IPMP), , is a natural monoterpenoid phenol derivative of ''p''-Cymene, isomeric with carvacrol, found in oil of thyme, and extracted from ''Thymus vulgaris'' (common thyme), ajwain, and vario ...

; and hexacosanol. In total, 22

flavonoid Flavonoids (or bioflavonoids; from the Latin word ''flavus'', meaning yellow, their color in nature) are a class of polyphenolic secondary metabolites found in plants, and thus commonly consumed in the diets of humans. Chemically, flavonoids ...

maltol Maltol is a naturally occurring organic compound that is used primarily as a flavor enhancer. It is found in the bark of larch tree, in pine needles, and in roasted malt (from which it gets its name). It is a white crystalline powder that is ...

glucoside A glucoside is a glycoside that is derived from glucose. Glucosides are common in plants, but rare in animals. Glucose is produced when a glucoside is hydrolysed by purely chemical means, or decomposed by fermentation or enzymes. The name was o ...

, phenolics, seven

cyanogenic glycosides In chemistry, a glycoside is a molecule in which a sugar is bound to another functional group via a glycosidic bond. Glycosides play numerous important roles in living organisms. Many plants store chemicals in the form of inactive glycosi ...

monoterpenoid Monoterpenes are a class of terpenes that consist of two isoprene units and have the molecular formula C10H16. Monoterpenes may be linear (acyclic) or contain rings (monocyclic and bicyclic). Modified terpenes, such as those containing oxygen funct ...

sesquiterpenoid Sesquiterpenes are a class of terpenes that consist of three isoprene units and often have the molecular formula C15H24. Like monoterpenes, sesquiterpenes may be cyclic or contain rings, including many unique combinations. Biochemical modificati ...

triterpenoid Triterpenes are a class of chemical compounds composed of three terpene units with the molecular formula C30H48; they may also be thought of as consisting of six isoprene units. Animals, plants and fungi all produce triterpenes, including squal ...

s, the polyterpene ficaprenol-11,

fatty acid In chemistry, particularly in biochemistry, a fatty acid is a carboxylic acid with an aliphatic chain, which is either saturated or unsaturated. Most naturally occurring fatty acids have an unbranched chain of an even number of carbon atoms, fr ...

s, and

caffeine Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class. It is mainly used recreationally as a cognitive enhancer, increasing alertness and attentional performance. Caffeine acts by blocking binding of adenosine t ...

have been found in the genus ''Turnera''. As of 2006, damiana's constituents have not been identified for their effects attributed to the whole herb. Damiana's

anxiolytic An anxiolytic (; also antipanic or antianxiety agent) is a medication or other intervention that reduces anxiety. This effect is in contrast to anxiogenic agents which increase anxiety. Anxiolytic medications are used for the treatment of anxi ...

properties might be due to

. The extract from damiana has been found to suppress aromatase activity, including the isolated compounds

pinocembrin Pinocembrin is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis Propolis or bee glue is a resinous mixture that honey bees produce by mixing saliva and beeswax with exudate gathere ...

and

Ecology

''T. diffusa'' is a host plant for the Mexican fritillary ('' Euptoieta hegesia''), a butterfly.

Misidentification in commerce

Viable plant and seed material sold as ''T. diffusa'' from both private and commercial sources largely turns out to be misidentified ''

Turnera ulmifolia ''Turnera ulmifolia'', the ramgoat dashalong or yellow alder, is a species of plant of family Passifloraceae, native to Mexico and the West Indies. A recent study found that yellow alder potentiated the antibiotic activity against methicillin-res ...

'' (a.k.a. "False Damiana"), a closely related species. This widespread issue has been noted by the scientific community, and has created much confusion among both amateur and professional horticulturists alike. While ''T. ulmifolia'' is similar in appearance, its chemical constituents and ethnobotanical uses are distinctly different. Mature stems of ''T. diffusa'' are woody, with small, grayed green leaves 13 to 16 mm long, 4.5 to 5.5 mm wide, obtuse at the apex, and strongly aromatic when crushed. ''T. ulmifolia'' is differentiated by herbaceous stems, larger blue-green leaves that are strongly dentate with a pointed apex, and only weakly aromatic. One scientific study however, demonstrated this confusion being mostly associated with horticultural commerce, and does not extend appreciably to commercial herbal products, most of which exhibit constituents that can be definitively traced to ''T. diffusa''.

References

External links

Damiana vault
at

Erowid Erowid, also called Erowid Center, is a non-profit educational organization that provides information about psychoactive plants and chemicals. Erowid documents legal and illegal substances, including their intended and adverse effects. Informat ...

''Damiana'' (www.rain-tree.com)
{{Taxonbar, from=Q932516 diffusa Plants described in 1820 Liqueurs Flora of South America Flora of Mexico Flora of Texas Mexican alcoholic drinks