Thottopalayam Thottimvirus
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Thottopalayam Thottimvirus
''Thottopalayam thottimvirus'', formerly ''Thottapalayam virus'', (TMPV) is single-stranded, enveloped, negative-sense RNA virus species of the genus '' Thottimvirus'' in the ''Bunyavirales'' order. It is the first hantavirus to be isolated from a shrew. It was discovered in India in 1964. Natural reservoir TPMV was first isolated from an Asian house shrew (''Suncus murinus'') in India in 1964. It is part of a group of hantaviruses which are hosted by shrews instead of rodents. These shrew-borne ''thottimviruses'' are not known to cause any known disease in humans, unlike the similar and related ''orthohantaviruses'' including Andes and Hantaan viruses, which cause lethal hemorrhagic fevers. TPMV was first isolated in Asian house shrews in Wenzhou of Zhejiang province, China. Virology Phylogenetic analysis has shown that Thottapalayam virus, and its closely related strains, is unique and forms a distinct lineage, unrelated to other hantaviruses. The closest hantavirus to ...
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Yong-Zhen Zhang
Zhang Yongzhen (), also known as Yong-Zhen Zhang, is a Chinese virologist known for his work relating to the COVID-19 pandemic. A professor at Fudan University, Zhang has discovered numerous RNA viruses and created a network of labs dedicated to monitoring new viruses. He led the team that sequenced and published the genome of SARS-CoV-2, the virus that causes COVID-19, in early January 2020. According to ''Time'', Zhang was the "saving grace" of the COVID-19 pandemic. Zhang's team's success in discovering and publishing the virus's genome allowed scientists to quickly design COVID-19 tests, fight the pandemic, and begin developing COVID-19 vaccines. A government order prohibited labs from publishing information about the virus at the time, but Zhang said he was not aware of the order, and they received no penalty for releasing the data. Zhang was named one of ''Natures 10: "ten people who helped shape science in 2020", and was winner of the 2020 ICG-15 '' GigaScience'' Prize ...
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Hantaviridae
''Hantaviridae'' is a family of viruses in the order ''Bunyavirales''. It is named for the Hantan River area in South Korea where an early outbreak of one of its species was observed. Taxonomy * '' Actantavirinae'' ** '' Actinovirus'' * '' Agantavirinae'' ** '' Agnathovirus'' * '' Mammantavirinae'' ** '' Loanvirus'' ** '' Mobatvirus'' ** ''Orthohantavirus ''Orthohantavirus'' is a genus of single-stranded, enveloped, negative-sense RNA viruses in the family '' Hantaviridae'' within the order ''Bunyavirales''. Members of this genus may be called orthohantaviruses or simply hantaviruses. Orthohantav ...'' ** '' Thottimvirus'' * '' Repantavirinae'' ** '' Reptillovirus'' References {{Taxonbar, from=Q29001075 Virus families Bunyavirales ...
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Viral Diseases
Viral means "relating to viruses" (small infectious agents). Viral may also refer to: Viral behavior, or virality Memetic behavior likened that of a virus, for example: * Viral marketing, the use of existing social networks to spread a marketing message * Viral phenomenon, relating to contagion theory or the "virality" of network culture, such as a meme * Viral video, a video that quickly attains a high popularity Titled works * ''Viral'' (2016 American film), a 2016 American science fiction horror drama * ''Viral'' (2016 Hindi film), an Indian Bollywood film based on social media * ''Viral'' (web series), a 2014 Brazilian comedy web series * '' V/H/S: Viral'', an American anthology horror film * '' Viral: The Search for the Origin of COVID-19'', a book by Alina Chand and Matt Ridley See also * ''Virals'', a novel series by Kathy Reichs * Virulence Virulence is a pathogen's or microorganism's ability to cause damage to a host. In most, especially in animal system ...
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Puumala Virus
''Puumala orthohantavirus'' (PUUV) is a species of ''Orthohantavirus''. Humans infected with the virus may develop a haemorrhagic fever with renal syndrome (HFRS) known as nephropathia epidemica. ''Puumala orthohantavirus'' HFRS is lethal in less than 0.5% of the cases.Discertation for doctoral exam; Distribution of Puumalavirus in Sweden
, by C. Ahlm, second paragraph; latest access 2012-06-04
Rarely, PUUV infection can cause Guillain-Barré syndrome. ''Puumala orthohantavirus'' was discovered and named in 1980 named after

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RNA Virus
An RNA virus is a virusother than a retrovirusthat has ribonucleic acid (RNA) as its genetic material. The nucleic acid is usually single-stranded RNA ( ssRNA) but it may be double-stranded (dsRNA). Notable human diseases caused by RNA viruses include the common cold, influenza, SARS, MERS, Covid-19, Dengue Virus, hepatitis C, hepatitis E, West Nile fever, Ebola virus disease, rabies, polio, mumps, and measles. The International Committee on Taxonomy of Viruses (ICTV) classifies RNA viruses as those that belong to ''Group III'', ''Group IV'' or ''Group V'' of the Baltimore classification system. This category excludes ''Group VI'', viruses with RNA genetic material but which use DNA intermediates in their life cycle: these are called retroviruses, including HIV-1 and HIV-2 which cause AIDS. As of May 2020, all known RNA viruses encoding an RNA-directed RNA polymerase are believed to form a monophyletic group, known as the realm '' Riboviria''. The majority of such RNA ...
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Tanganya Virus
Tanganya virus (TGNV) is an enveloped, single-stranded, negative-sense RNA virus, possibly of the genus orthohantavirus in the Bunyavirales ''Bunyavirales'' is an order of segmented negative-strand RNA viruses with mainly tripartite genomes. Member viruses infect arthropods, plants, protozoans, and vertebrates. It is the only order in the class ''Ellioviricetes''. The name ''Bunyavir ... order. It is the second indigenous Murinae-associated African hantavirus to be discovered. It has a low sequence similarity to other hantaviruses and serologically distinct from other hantaviruses.Boris Klempa, Elisabeth Fichet-Calvet, Emilie Lecompte, S. et al. Novel Hantavirus Sequences in Shrew, Guinea. Emerg Infect Dis. 2007 March; 13(3): 520–522. Its host is '' Crocidura theresae''. References External links CDC's Hantavirus Technical Information Index pageVirus Pathogen Database and Analysis Resource (ViPR): Bunyaviridae {{Taxonbar, from=Q16978196 Viral diseases Hantavi ...
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Imjin Virus
''Imjin thottimvirus'' (MJNV) is a single-stranded, enveloped, negative-sense RNA virus of the orthohantavirus genus in the Bunyavirales order. It is a newly identified hantavirus isolated from the lung tissues of Ussuri white-toothed shrews of the species ''Crocidura lasiura'' (order Soricomorpha, family Soricidae, subfamily Crocidurinae) captured near the demilitarized zone in the Republic of Korea during 2004 and 2005. Virology Phylogenetic analyses demonstrates a common ancestry with '' Thottopalayam thottimvirus'' suggesting early evolutionary divergence. It is still unknown if MJNV is pathogenic for humans. MJNV has been shown to be a genetically unique hantavirus. Multiple strains have been isolated from the lung tissues of Ussuri white-toothed shrews captured between 2004 and 2010. Partial M- and L-segment sequences from lung tissues of 12 of 37 (32.4%) anti-MJNV IgG antibody-positive shrews revealed that the 12 MJNV strains differed by 0–12.2% and 0–2.3% at the n ...
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China
China, officially the People's Republic of China (PRC), is a country in East Asia. It is the world's most populous country, with a population exceeding 1.4 billion, slightly ahead of India. China spans the equivalent of five time zones and borders fourteen countries by land, the most of any country in the world, tied with Russia. Covering an area of approximately , it is the world's third largest country by total land area. The country consists of 22 provinces, five autonomous regions, four municipalities, and two Special Administrative Regions (Hong Kong and Macau). The national capital is Beijing, and the most populous city and financial center is Shanghai. Modern Chinese trace their origins to a cradle of civilization in the fertile basin of the Yellow River in the North China Plain. The semi-legendary Xia dynasty in the 21st century BCE and the well-attested Shang and Zhou dynasties developed a bureaucratic political system to serve hereditary monarchies, or dyna ...
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Bunyavirales
''Bunyavirales'' is an order of segmented negative-strand RNA viruses with mainly tripartite genomes. Member viruses infect arthropods, plants, protozoans, and vertebrates. It is the only order in the class ''Ellioviricetes''. The name ''Bunyavirales'' derives from Bunyamwera, where the original type species ''Bunyamwera orthobunyavirus'' was first discovered. ''Ellioviricetes'' is named in honor of late virologist Richard M. Elliott for his early work on bunyaviruses. Bunyaviruses belong to the fifth group of the Baltimore classification system, which includes viruses with a negative-sense, single-stranded RNA genome. They have an enveloped, spherical virion. Though generally found in arthropods or rodents, certain viruses in this order occasionally infect humans. Some of them also infect plants. In addition, there is a group of bunyaviruses whose replication is restricted to arthropods and is known as insect-specific bunyaviruses. A majority of bunyaviruses are vector-borne ...
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Zhejiang
Zhejiang ( or , ; , also romanized as Chekiang) is an eastern, coastal province of the People's Republic of China. Its capital and largest city is Hangzhou, and other notable cities include Ningbo and Wenzhou. Zhejiang is bordered by Jiangsu and Shanghai to the north, Anhui to the northwest, Jiangxi to the west and Fujian to the south. To the east is the East China Sea, beyond which lies the Ryukyu Islands. The population of Zhejiang stands at 64.6 million, the 8th highest among China. It has been called 'the backbone of China' due to being a major driving force in the Chinese economy and being the birthplace of several notable persons, including the Chinese Nationalist leader Chiang Kai-shek and entrepreneur Jack Ma. Zhejiang consists of 90 counties (incl. county-level cities and districts). The area of Zhejiang was controlled by the Kingdom of Yue during the Spring and Autumn period. The Qin Empire later annexed it in 222 BC. Under the late Ming dynasty and the Qing ...
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Wenzhou
Wenzhou (pronounced ; Wenzhounese: Yuziou ”y33–11 tÉ•iɤu33–32 ), historically known as Wenchow is a prefecture-level city in southeastern Zhejiang province in the People's Republic of China. Wenzhou is located at the extreme south east of Zhejiang Province with its borders connecting to Lishui on the west, Taizhou on the north, and Fujian to the south. It is surrounded by mountains, the East China Sea, and 436 islands, while its lowlands are almost entirely along its East China Sea coast, which is nearly in length. Most of Wenzhou's area is mountainous as almost 76 percent of its surface area is classified as mountains and hills. It is said that Wenzhou has 7/10 mountains, 1/10 water, and 2/10 farmland. At the time of the 2010 Chinese census, 3,039,500 people lived in Wenzhou's urban area; the area under its jurisdiction (which includes three satellite cities and six counties) held a population of 9,122,100 of which 31.16% are non-local residents from outside of Wenz ...
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