Sarah Gilbert (scientist)
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Sarah Gilbert (scientist)
Dame Sarah Catherine Gilbert (born April 1962) is an English vaccinologist who is a Professor of Vaccinology at the University of Oxford and co-founder of Vaccitech. She specialises in the development of vaccines against influenza and emerging viral pathogens. She led the development and testing of the universal flu vaccine, which underwent clinical trials in 2011. In January 2020, she read a report on ProMED-mail about four people in China suffering from a strange kind of pneumonia of unknown origin in Wuhan. Within two weeks, a vaccine had been designed at Oxford against the new pathogen, which later became known as COVID-19. On 30 December 2020, the Oxford–AstraZeneca COVID-19 vaccine she co-developed with the Oxford Vaccine Group was approved for use in the UK. As of January 2022, more than 2.5 billion doses of the vaccine have been released to more than 170 countries worldwide. Early life and education Sarah Catherine Gilbert was born in Kettering, Northamptonshire. He ...
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Dame
''Dame'' is an honorific title and the feminine form of address for the honour of damehood in many Christian chivalric orders, as well as the Orders, decorations, and medals of the United Kingdom, British honours system and those of several other Commonwealth realms, such as Australia and New Zealand, with the masculine form of address being ''Sir''. It is the female equivalent for knighthood, which is traditionally granted to males. Dame is also style used by baronetesses Suo jure, in their own right. A woman appointed to the grades of the Dame Commander or Dame Grand Cross of the Order of Saint John (Bailiwick of Brandenburg), Order of Saint John, Equestrian Order of the Holy Sepulchre, Most Honourable Order of the Bath, the Most Distinguished Order of Saint Michael and Saint George, the Royal Victorian Order, or the Most Excellent Order of the British Empire becomes a dame. A Central European order in which female members receive the rank of Dame is the Order of St. George (H ...
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Pneumonia
Pneumonia is an inflammatory condition of the lung primarily affecting the small air sacs known as alveoli. Symptoms typically include some combination of productive or dry cough, chest pain, fever, and difficulty breathing. The severity of the condition is variable. Pneumonia is usually caused by infection with viruses or bacteria, and less commonly by other microorganisms. Identifying the responsible pathogen can be difficult. Diagnosis is often based on symptoms and physical examination. Chest X-rays, blood tests, and culture of the sputum may help confirm the diagnosis. The disease may be classified by where it was acquired, such as community- or hospital-acquired or healthcare-associated pneumonia. Risk factors for pneumonia include cystic fibrosis, chronic obstructive pulmonary disease (COPD), sickle cell disease, asthma, diabetes, heart failure, a history of smoking, a poor ability to cough (such as following a stroke), and a weak immune system. Vaccines to ...
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Eastern Daily Press
The ''Eastern Daily Press'' (''EDP'') is a regional newspaper covering Norfolk, northern parts of Suffolk and eastern Cambridgeshire, and is published daily in Norwich, UK. Founded in 1870 as a broadsheet called the ''Eastern Counties Daily Press'', it changed its name to the ''Eastern Daily Press'' in 1872. It switched to the compact ( tabloid) format in the mid-1990s. The paper is now owned and published by Archant, formerly known as Eastern Counties Newspapers Group. It aims to represent the interests of the local population in the region in a non-partisan way, its mission statement being to "champion a fair deal for the future prosperity of the region". Despite its commitment to regional issues, the ''EDP'' also covers national (and international) news and sport. The paper also produces a sister edition, the ''Norwich Evening News''. Notable editors *Edmund Rogers Edmund Dawson Rogers (7 August 1823 – 28 September 1910), was an English journalist and spiritualist. ...
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Biological Sciences
Biology is the scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of cells that process hereditary information encoded in genes, which can be transmitted to future generations. Another major theme is evolution, which explains the unity and diversity of life. Energy processing is also important to life as it allows organisms to move, grow, and reproduce. Finally, all organisms are able to regulate their own internal environments. Biologists are able to study life at multiple levels of organization, from the molecular biology of a cell to the anatomy and physiology of plants and animals, and evolution of populations.Based on definition from: Hence, there are multiple subdisciplines within biology, each defined by the nature of their research questions and the tools that they use. Like other scientists, biologists use the scientific ...
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GCE Ordinary Level
The O-Level (Ordinary Level) is a subject-based qualification conferred as part of the General Certificate of Education. It was introduced in place of the School Certificate in 1951 as part of an educational reform alongside the more in-depth and academically rigorous A-Level (Advanced Level) in England, Wales and Northern Ireland. Those three jurisdictions replaced O-Level gradually with General Certificate of Secondary Education (GCSE) completely by 1988 and, the International General Certificate of Secondary Education (IGCSE) over time. The Scottish equivalent was the O-grade (replaced by the Standard Grade). The AO-Level (Alternative Ordinary Level) was formerly available in most subject areas. Sometimes incorrectly known as the Advanced Ordinary Level, the AO Level syllabus and examination both assumed a higher degree of maturity on the part of candidates, and employed teaching methods more commonly associated with A-Level study. The AO Level was discontinued, with final ...
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Newsround
''Newsround'' (stylised as ''newsround'', and originally called ''John Craven's Newsround'' before his departure in 1989) is a BBC children's news programme, which has run continuously since 4 April 1972. It was one of the world's first television news magazines aimed specifically at children. Initially commissioned as a short series by BBC Children's Department, who held editorial control, its facilities were provided by BBC News. The programme is aimed at 5 to 17-year-olds. History Originally known as ''John Craven's Newsround'', it was first presented by John Craven between 4 April 1972 and 22 June 1989. Originally, stand-in presenters, such as Richard Whitmore, came from the main BBC News bulletins. In 1987, the show was renamed ''Newsround'', and was presented by a rotating team including with Craven in the dual role of chief presenter and programme editor. The programme gradually developed its own small reporting team, including Helen Rollason, Lucy Mathen, and long-se ...
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Financial Times
The ''Financial Times'' (''FT'') is a British daily newspaper printed in broadsheet and published digitally that focuses on business and economic current affairs. Based in London, England, the paper is owned by a Japanese holding company, Nikkei, with core editorial offices across Britain, the United States and continental Europe. In July 2015, Pearson sold the publication to Nikkei for £844 million (US$1.32 billion) after owning it since 1957. In 2019, it reported one million paying subscriptions, three-quarters of which were digital subscriptions. The newspaper has a prominent focus on financial journalism and economic analysis over generalist reporting, drawing both criticism and acclaim. The daily sponsors an annual book award and publishes a " Person of the Year" feature. The paper was founded in January 1888 as the ''London Financial Guide'' before rebranding a month later as the ''Financial Times''. It was first circulated around metropolitan London by James Sherid ...
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Shoemaking
Shoemaking is the process of making footwear. Originally, shoes were made one at a time by hand, often by groups of shoemakers, or cobblers (also known as '' cordwainers''). In the 18th century, dozens or even hundreds of masters, journeymen and apprentices (both men and women) would work together in a shop, dividing up the work into individual tasks. A customer could come into a shop, be individually measured, and return to pick up their new shoes in as little as a day. Everyone needed shoes, and the median price for a pair was about one day’s wages for an average journeyman. The shoemaking trade flourished in the eighteenth and early nineteenth centuries but began to be affected by industrialization in the later nineteenth century. Traditional handicraft shoemaking has now been largely superseded in volume of shoes produced by industrial mass production of footwear, but not necessarily in quality, attention to detail, or craftsmanship. Today, most shoes are made on a volum ...
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Northamptonshire
Northamptonshire (; abbreviated Northants.) is a county in the East Midlands of England. In 2015, it had a population of 723,000. The county is administered by two unitary authorities: North Northamptonshire and West Northamptonshire. It is known as "The Rose of the Shires". Covering an area of 2,364 square kilometres (913 sq mi), Northamptonshire is landlocked between eight other counties: Warwickshire to the west, Leicestershire and Rutland to the north, Cambridgeshire to the east, Bedfordshire to the south-east, Buckinghamshire to the south, Oxfordshire to the south-west and Lincolnshire to the north-east – England's shortest administrative county boundary at 20 yards (19 metres). Northamptonshire is the southernmost county in the East Midlands. Apart from the county town of Northampton, other major population centres include Kettering, Corby, Wellingborough, Rushden and Daventry. Northamptonshire's county flower is the cowslip. The Soke of Peterborough fal ...
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Kettering
Kettering is a market and industrial town in North Northamptonshire, England. It is located north of London and north-east of Northampton, west of the River Ise, a tributary of the River Nene. The name means "the place (or territory) of Ketter's people (or kinsfolk)".R.L. Greenall: A History of Kettering, Phillimore & Co. Ltd, 2003, . p.7. In the 2011 census Kettering's built-up area had a population of 63,675. It is part of the East Midlands, along with other towns in Northamptonshire. There is a growing commuter population as it is on the Midland Main Line railway, with East Midlands Railway services direct to London St Pancras International taking about an hour. Early history Kettering means "the place (or territory) of Ketter's people (or kinsfolk)". Spelt variously Cytringan, Kyteringas and Keteiringan in the 10th century, although the origin of the name appears to have baffled place-name scholars in the 1930s, words and place-names ending with "-ing" usually derive f ...
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Oxford Vaccine Group
The Oxford Vaccine Group (OVG) is a vaccine research group within the Department of Paediatrics at the University of Oxford. It was founded in 1994 by Professor E. Richard Moxon, was initially based at the John Radcliffe Hospital, and moved in 2003 to its current location in the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM) at the Churchill Hospital in Oxford, England. The group, led by Professor Andrew Pollard since 2001, comprises around 75 members across a number of disciplines, including consultants in paediatrics and vaccinology, clinical research fellows, research nurses, statisticians, post-doctoral laboratory scientists, research assistants and DPhil students. OVG came to public prominence in 2020 for the vaccine it created to combat COVID-19. Aims and background OVG carries out research on vaccines to improve human health. It works to enhance the understanding of immunity, studies the epidemiology of infectious diseases, and conducts clinical tr ...
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Oxford–AstraZeneca COVID-19 Vaccine
The Oxford–AstraZeneca COVID19 vaccine, sold under the brand names Covishield and Vaxzevria among others, is a viral vector vaccine for prevention of COVID-19. Developed in the United Kingdom by Oxford University and British-Swedish company AstraZeneca, using as a vector the modified chimpanzee adenovirus ChAdOx1. The vaccine is given by intramuscular injection. Studies carried out in 2020 showed that the efficacy of the vaccine is 76.0% at preventing symptomatic COVID-19 beginning at 22 days following the first dose, and 81.3% after the second dose. A study in Scotland found that, for symptomatic COVID-19 infection after the second dose, the vaccine is 81% effective against the Alpha variant (lineage B.1.1.7), and 61% against the Delta variant (lineage B.1.617.2). The vaccine is stable at refrigerator temperatures and has a good safety profile, with side effects including injection-site pain, headache, and nausea, all generally resolving within a few days. More rarely, ...
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