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Oxford Vaccine Group
The Oxford Vaccine Group (OVG) is a vaccine research group within the Department of Paediatrics at the University of Oxford. It was founded in 1994 by Professor E. Richard Moxon, was initially based at the John Radcliffe Hospital, and moved in 2003 to its current location in the Centre for Clinical Vaccinology and Tropical Medicine (CCVTM) at the Churchill Hospital in Oxford, England. The group, led by Professor Andrew Pollard since 2001, comprises around 75 members across a number of disciplines, including consultants in paediatrics and vaccinology, clinical research fellows, research nurses, statisticians, post-doctoral laboratory scientists, research assistants and DPhil students. OVG came to public prominence in 2020 for the vaccine it created to combat COVID-19. Aims and background OVG carries out research on vaccines to improve human health. It works to enhance the understanding of immunity, studies the epidemiology of infectious diseases, and conducts clinical tr ...
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Churchill Hospital
The Churchill Hospital is a teaching hospital in Oxford, England. It is managed by the Oxford University Hospitals NHS Foundation Trust. History The original hospital on the site was built in 1940 with the intention of providing medical aid to people suffering orthopaedic injuries as a result of air raids during the Second World War. This proved unnecessary, and the building was leased to the United States Army medical services, who were relocating from Basingstoke. The new American hospital was named after Sir Winston Churchill, the then Prime Minister, and was opened by the Duchess of Kent on 27 January 1942. The US Army left the hospital at the end of the war and it was taken over by the local council and reopened as a conventional hospital in January 1946. The Churchill Hospital came under common management with the John Radcliffe Hospital in April 1993 and with the Nuffield Orthopaedic Centre in November 2011. New cancer treatment facilities were procured under a Private Fi ...
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Meningococcal Vaccine
Meningococcal vaccine refers to any vaccine used to prevent infection by ''Neisseria meningitidis''. Different versions are effective against some or all of the following types of meningococcus: A, B, C, W-135, and Y. The vaccines are between 85 and 100% effective for at least two years. They result in a decrease in meningitis and sepsis among populations where they are widely used. They are given either by injection into a muscle or just under the skin. The World Health Organization recommends that countries with a moderate or high rate of disease or with frequent outbreaks should routinely vaccinate. In countries with a low risk of disease, they recommend that high risk groups should be immunized. In the African meningitis belt efforts to immunize all people between the ages of one and thirty with the meningococcal A conjugate vaccine are ongoing. In Canada and the United States the vaccines effective against four types of meningococcus (A, C, W, and Y) are recommended routi ...
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Nepal
Nepal (; ne, नेपाल ), formerly the Federal Democratic Republic of Nepal ( ne, सङ्घीय लोकतान्त्रिक गणतन्त्र नेपाल ), is a landlocked country in South Asia. It is mainly situated in the Himalayas, but also includes parts of the Indo-Gangetic Plain, bordering the Tibet Autonomous Region of China to the north, and India in the south, east, and west, while it is narrowly separated from Bangladesh by the Siliguri Corridor, and from Bhutan by the Indian state of Sikkim. Nepal has a diverse geography, including fertile plains, subalpine forested hills, and eight of the world's ten tallest mountains, including Mount Everest, the highest point on Earth. Nepal is a multi-ethnic, multi-lingual, multi-religious and multi-cultural state, with Nepali as the official language. Kathmandu is the nation's capital and the largest city. The name "Nepal" is first recorded in texts from the Vedic period of the India ...
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Patan Hospital
Patan Hospital is a teaching hospital for the Patan Academy of Health Sciences. Patan Hospital is one of the largest hospitals in Nepal. It uses modern equipment and facilities to provide treatment for almost 320,000 outpatients and 20,000 inpatients every year. Patan Hospital staff conduct more than 10,000 operations annually. The hospital has been operating with an annual revenue of around US$3.5 million. It serves people from every district of Nepal, from the remote villages as well as from the Kathmandu valley. Patan Hospital has 320 beds, which has increased to 450, after the completion of its maternity ward building construction. Services offered *24-Hour Emergency Service *Inpatient Medical and Surgical care * Obstetrics and Gynecology *Birthing Center * Pediatrics *Orthopedics *Psychiatry *ENT * Dentistry *Dermatology *Intensive Care Unit *Outpatient Services *Emergency medicine service *General Practice clinics *Private Clinic *Pathology Pathology is the study o ...
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Clinical Infectious Diseases
''Clinical Infectious Diseases'' is a peer-reviewed medical journal published by Oxford University Press covering research on the pathogenesis, clinical investigation, medical microbiology, diagnosis, immune mechanisms, and treatment of diseases caused by infectious agents. It includes articles on antimicrobial resistance, bioterrorism, emerging infections, food safety, hospital epidemiology, and HIV/AIDS. It also features highly focused brief reports, review articles, editorials, commentaries, and supplements. The journal is published on behalf of the Infectious Diseases Society of America. According to the ''Journal Citation Reports'', the journal had a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 9.079, ranking it 18th out of 162 journals in the categ ...
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Meningococcal Vaccine
Meningococcal vaccine refers to any vaccine used to prevent infection by ''Neisseria meningitidis''. Different versions are effective against some or all of the following types of meningococcus: A, B, C, W-135, and Y. The vaccines are between 85 and 100% effective for at least two years. They result in a decrease in meningitis and sepsis among populations where they are widely used. They are given either by injection into a muscle or just under the skin. The World Health Organization recommends that countries with a moderate or high rate of disease or with frequent outbreaks should routinely vaccinate. In countries with a low risk of disease, they recommend that high risk groups should be immunized. In the African meningitis belt efforts to immunize all people between the ages of one and thirty with the meningococcal A conjugate vaccine are ongoing. In Canada and the United States the vaccines effective against four types of meningococcus (A, C, W, and Y) are recommended routi ...
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Thames Valley
The Thames Valley is an informally-defined sub-region of South East England, centred on the River Thames west of London, with Oxford as a major centre. Its boundaries vary with context. The area is a major tourist destination and economic hub, includes part of the M4 corridor, and is sometimes referred to as England's Silicon Valley due to the concentration of high-technology companies. The area east of Reading is defined by Natural England as the Thames Valley National Character Area, while Thames Valley Police cover the counties of Berkshire, Buckinghamshire and Oxfordshire. Geography As a National Character Area, the Thames Valley is bounded to the west by Reading, fanning out roughly in a wedge shape towards the fringes of London. It contains 38 Sites of Special Scientific Interest and significant amounts of broadleaf forest, including Burnham Beeches, Windsor Great Park and Richmond Park. Economy The Thames Valley is a technology hub centred around Reading, consider ...
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European Medicines Agency
The European Medicines Agency (EMA) is an agency of the European Union (EU) in charge of the evaluation and supervision of medicinal products. Prior to 2004, it was known as the European Agency for the Evaluation of Medicinal Products or European Medicines Evaluation Agency (EMEA).Set up by EC Regulation No. 2309/93 as the European Agency for the Evaluation of Medicinal Products, and renamed by EC Regulation No. 726/2004 to the European Medicines Agency, it had the acronym EMEA until December 2009. The European Medicines Agency does not call itself EMA either – it has no official acronym but may reconsider if EMA becomes commonly accepted (secommunication on new visual identity an). The EMA was set up in 1995, with funding from the European Union and the pharmaceutical industry, as well as indirect subsidy from member states, its stated intention to harmonise (but not replace) the work of existing national medicine regulatory bodies. The hope was that this plan would not onl ...
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Meningococcal
''Neisseria meningitidis'', often referred to as meningococcus, is a Gram-negative bacterium that can cause meningitis and other forms of meningococcal disease such as meningococcemia, a life-threatening sepsis. The bacterium is referred to as a coccus because it is round, and more specifically a diplococcus because of its tendency to form pairs. About 10% of adults are carriers of the bacteria in their nasopharynx. As an exclusively human pathogen, it is the main cause of bacterial meningitis in children and young adults, causing developmental impairment and death in about 10% of cases. It causes the only form of bacterial meningitis known to occur epidemically, mainly in Africa and Asia. It occurs worldwide in both epidemic and endemic form. ''N. meningitidis'' is spread through saliva and respiratory secretions during coughing, sneezing, kissing, chewing on toys and through sharing a source of fresh water. It has also been reported to be transmitted through oral sex and cause ...
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Joint Committee On Vaccination And Immunisation
The Joint Committee on Vaccination and Immunisation (JCVI) is an National Immunization Technical Advisory Group, independent expert advisory committee that advises United Kingdom health departments on immunisation, making recommendations concerning vaccination schedules and vaccine safety. It has a statutory role in England and Wales, and health departments in Scotland and Northern Ireland may choose to accept its advice. History The committee was established in 1963, having been until then an advisory board for Polio vaccine, polio immunisation. It gained statutory status as the Standing Advisory Committee on Vaccination and Immunisation, a non-departmental public body advising the Secretary of State for Social Services and the Secretary of State for Wales, under the National Health Service (Standing Advisory Committees) Order 1981. Since the Devolution in the United Kingdom, devolution of government powers to Wales, the JCVI continues to advise Welsh ministers. For England, ...
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NHS Trust
An NHS trust is an organisational unit within the National Health Services of England and Wales, generally serving either a geographical area or a specialised function (such as an ambulance service). In any particular location there may be several trusts involved in the different aspects of providing healthcare to the local population. there were altogether 217 trusts, and they employ around 800,000 of the NHS's 1.2 million staff. History NHS trusts were established under the National Health Service and Community Care Act 1990 and were set up in five waves. Each one was established by a Statutory Instrument. NHS trusts are not trusts in the legal sense but are in effect public sector corporations. Each trust is headed by a board consisting of executive and non-executive directors, and is chaired by a non-executive director. There were about 2,200 non-executives across 470 organisations in the NHS in England in 2015. Non-executive directors are recruited by open advertisement. ...
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Clinical Trials Unit
Clinical trials units (CTU) are specialised biomedical research units which design, centrally coordinate and analyse clinical trials and other studies. Some CTUs specialise in different methodologies, such as randomised controlled trials, cluster randomised trials, surgical trials, and health services research. Some specialise in one disease type, whereas others are generic units. Some CTUs focus on specific phases and types of clinical trials; others conduct all phases and types of trial. United Kingdom The UKCRC evaluates CTUs in the UK and they may be given either Full or Provisional CTU registration status. All Registered CTUs are required to provide evidence that their work is of high quality by demonstrating (1) experience of coordinating multi-centre randomised controlled trials or other well-designed studies, (2) a presence of a core team of expert staff to develop studies, (3) a presence of robust quality assurance systems and processes to meet appropriate regulations a ...
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