Sir David Bruce
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Sir David Bruce
Major-General Sir David Bruce (29 May 1855 – 27 November 1931) was an Australian-born British pathologist and microbiologist who made some of the key contributions in tropical medicine. In 1887, he discovered a bacterium, now called ''Brucella'', that caused what was known as Malta fever. In 1894, he discovered a protozoan parasite, named ''Trypanosoma brucei'', as the causative pathogen of nagana (animal trypanosomiasis). Working in the Army Medical Services and the Royal Army Medical Corps, Bruce's major scientific collaborator was his microbiologist wife Mary Elizabeth Bruce (''née'' Steele), with whom he published around thirty technical papers out of his 172 papers. In 1886, he was chairman of the Malta Fever Commission that investigated the deadly disease, by which he identified a specific bacterium as the cause. Later, with his wife, he investigated an outbreak of animal disease called nagana in Zululand and discovered the protozoan parasite responsible for it. He ...
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Melbourne
Melbourne ( ; Boonwurrung/Woiwurrung: ''Narrm'' or ''Naarm'') is the capital and most populous city of the Australian state of Victoria, and the second-most populous city in both Australia and Oceania. Its name generally refers to a metropolitan area known as Greater Melbourne, comprising an urban agglomeration of 31 local municipalities, although the name is also used specifically for the local municipality of City of Melbourne based around its central business area. The metropolis occupies much of the northern and eastern coastlines of Port Phillip Bay and spreads into the Mornington Peninsula, part of West Gippsland, as well as the hinterlands towards the Yarra Valley, the Dandenong and Macedon Ranges. It has a population over 5 million (19% of the population of Australia, as per 2021 census), mostly residing to the east side of the city centre, and its inhabitants are commonly referred to as "Melburnians". The area of Melbourne has been home to Aboriginal ...
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Malta Fever
Brucellosis is a highly contagious zoonosis caused by ingestion of unpasteurized milk or undercooked meat from infected animals, or close contact with their secretions. It is also known as undulant fever, Malta fever, and Mediterranean fever. The bacteria causing this disease, ''Brucella'', are small, Gram-negative, nonmotile, nonspore-forming, rod-shaped ( coccobacilli) bacteria. They function as facultative intracellular parasites, causing chronic disease, which usually persists for life. Four species infect humans: ''B. abortus'', ''B. canis'', ''B. melitensis'', and ''B. suis''. ''B. abortus'' is less virulent than ''B. melitensis'' and is primarily a disease of cattle. ''B. canis'' affects dogs. ''B. melitensis'' is the most virulent and invasive species; it usually infects goats and occasionally sheep. ''B. suis'' is of intermediate virulence and chiefly infects pigs. Symptoms include profuse sweating and joint and muscle pain. Brucellosis has been recognized in animals and ...
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Stirling High School
Stirling High School is a state high school for 11- to 18-year-olds run by Stirling Council in Stirling, Scotland. It is one of seven high schools in the Stirling district, and has approximately 972 pupils. It is located on Torbrex Farm Road, near Torbrex Village in the suburbs of Stirling, previously being situated on the old volcanic rock where Stirling Castle lies and on Ogilvie Road. The headteacher of the school is Paul Cassidy. The school operates a house system. The five houses are Douglas, Eccles, Randolph, Snowdon and Stewart. Originally established for the training of ecclesiastics, it began as the seminary of the Church of the Holy Rude, founded in the reign of David I in 1129. Both the church and school, along with those of Perth, were brought under the charge of the monks of the Church of the Holy Trinity of Dunfermline in 1173. New school buildings The school now operates from a new building on the former site of Williamfield Cricket Pitches, ex-home to Stir ...
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Stirling
Stirling (; sco, Stirlin; gd, Sruighlea ) is a city in central Scotland, northeast of Glasgow and north-west of Edinburgh. The market town, surrounded by rich farmland, grew up connecting the royal citadel, the medieval old town with its merchants and tradesmen, the Old Bridge and the port. Located on the River Forth, Stirling is the administrative centre for the Stirling council area, and is traditionally the county town of Stirlingshire. Proverbially it is the strategically important "Gateway to the Highlands". It has been said that "Stirling, like a huge brooch clasps Highlands and Lowlands together". Similarly "he who holds Stirling, holds Scotland" is often quoted. Stirling's key position as the lowest bridging point of the River Forth before it broadens towards the Firth of Forth made it a focal point for travel north or south. When Stirling was temporarily under Anglo-Saxon sway, according to a 9th-century legend, it was attacked by Danish invaders. The sound of a ...
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Airth
Airth is a Royal Burgh, village, former trading port and civil parish in Falkirk, Scotland. It is north of Falkirk town and sits on the banks of the River Forth. Airth lies on the A905 road between Grangemouth and Stirling and is overlooked by Airth Castle; the village retains two market crosses and a small number of historic houses. At the time of the 2001 census the village had a population of 1,273 residentsScotland's Census Results Online - Comparative Population Profile: Airth Locality
www.scrol.gov.uk. Retrieved 2008-08-31
but this has been revised to 1,660 according to a 2008 estimate.
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Brucellosis
Brucellosis is a highly contagious zoonosis caused by ingestion of unpasteurized milk or undercooked meat from infected animals, or close contact with their secretions. It is also known as undulant fever, Malta fever, and Mediterranean fever. The bacteria causing this disease, ''Brucella'', are small, Gram-negative, nonmotile, nonspore-forming, rod-shaped ( coccobacilli) bacteria. They function as facultative intracellular parasites, causing chronic disease, which usually persists for life. Four species infect humans: ''B. abortus'', ''B. canis'', ''B. melitensis'', and ''B. suis''. ''B. abortus'' is less virulent than ''B. melitensis'' and is primarily a disease of cattle. ''B. canis'' affects dogs. ''B. melitensis'' is the most virulent and invasive species; it usually infects goats and occasionally sheep. ''B. suis'' is of intermediate virulence and chiefly infects pigs. Symptoms include profuse sweating and joint and muscle pain. Brucellosis has been recognized in animals and ...
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Disease Vector
In epidemiology, a disease vector is any living agent that carries and transmits an infectious pathogen to another living organism; agents regarded as vectors are organisms, such as parasites or microbes. The first major discovery of a disease vector came from Ronald Ross in 1897, who discovered the malaria pathogen when he dissected a mosquito. Arthropods Arthropods form a major group of pathogen vectors with mosquitoes, flies, sand flies, lice, fleas, ticks, and mites transmitting a huge number of pathogens. Many such vectors are haematophagous, which feed on blood at some or all stages of their lives. When the insects feed on blood, the pathogen enters the blood stream of the host. This can happen in different ways. The ''Anopheles'' mosquito, a vector for malaria, filariasis, and various arthropod-borne-viruses (arboviruses), inserts its delicate mouthpart under the skin and feeds on its host's blood. The parasites the mosquito carries are usually located in its salivary gl ...
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African Trypanosomiasis
African trypanosomiasis, also known as African sleeping sickness or simply sleeping sickness, is an insect-borne parasitic infection of humans and other animals. It is caused by the species ''Trypanosoma brucei''. Humans are infected by two types, ''Trypanosoma brucei gambiense'' (TbG) and '' Trypanosoma brucei rhodesiense'' (TbR). TbG causes over 98% of reported cases. Both are usually transmitted by the bite of an infected tsetse fly and are most common in rural areas. Initially, the first stage of the disease is characterized by fevers, headaches, itchiness, and joint pains, beginning one to three weeks after the bite. Weeks to months later, the second stage begins with confusion, poor coordination, numbness, and trouble sleeping. Diagnosis is by finding the parasite in a blood smear or in the fluid of a lymph node. A lumbar puncture is often needed to tell the difference between first- and second-stage disease. If the disease is not treated quickly it can lead to death. P ...
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Royal Society
The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, recognising excellence in science, supporting outstanding science, providing scientific advice for policy, education and public engagement and fostering international and global co-operation. Founded on 28 November 1660, it was granted a royal charter by King Charles II as The Royal Society and is the oldest continuously existing scientific academy in the world. The society is governed by its Council, which is chaired by the Society's President, according to a set of statutes and standing orders. The members of Council and the President are elected from and by its Fellows, the basic members of the society, who are themselves elected by existing Fellows. , there are about 1,700 fellows, allowed to use the postnominal title FRS (Fellow of the ...
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Sleeping Sickness Commission
The Sleeping Sickness Commission was a medical project established by the British Royal Society to investigate the outbreak of African sleeping sickness or African trypanosomiasis in Africa at the turn of the 20th century. The outbreak of the disease started in 1900 in Uganda, which was at the time a protectorate of the British Empire. The initial team in 1902 consisted of Aldo Castellani and George Carmichael Low, both from the London School of Hygiene and Tropical Medicine, and Cuthbert Christy, a medical officer on duty in Bombay, India. From 1903, David Bruce of the Royal Army Medical Corps and David Nunes Nabarro of the University College Hospital took over the leadership. The commission established that species of blood protozoan called ''Trypanosoma brucei'', named after Bruce, was the causative parasite of sleeping sickness. Background Symptoms of sleeping sickness in animals were evident in ancient Egyptian writings. Records of Arabian traders in the Middle Ages menti ...
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Zulu Kingdom
The Zulu Kingdom (, ), sometimes referred to as the Zulu Empire or the Kingdom of Zululand, was a monarchy in Southern Africa. During the 1810s, Shaka established a modern standing army that consolidated rival clans and built a large following which ruled a wide expanse of Southern Africa that extended along the coast of the Indian Ocean from the Tugela River in the south to the Pongola River in the north. A bitter civil war in the mid-19th century erupted which culminated in the 1859 Battle of Ndondakusuka between the brothers Cetshwayo and Mbuyazi. In 1879, a British force invaded Zululand, beginning the Anglo-Zulu War. After an initial Zulu victory at the Battle of Isandlwana in January, the British regrouped and defeated the Zulus in July during the Battle of Ulundi, ending the war. The area was absorbed into the Colony of Natal and later became part of the Union of South Africa. History Rise under Shaka Shaka was the illegitimate son of Senzangakhona, Chief of the ...
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Royal Army Medical Corps
The Royal Army Medical Corps (RAMC) is a specialist corps in the British Army which provides medical services to all Army personnel and their families, in war and in peace. The RAMC, the Royal Army Veterinary Corps, the Royal Army Dental Corps and Queen Alexandra's Royal Army Nursing Corps form the Army Medical Services. History Origins Medical services in the British armed services date from the formation of the Standing Regular Army after the Restoration of Charles II in 1660. Prior to this, from as early as the 13th century there are records of surgeons and physicians being appointed by the English army to attend in times of war; but this was the first time a career was provided for a Medical Officer (MO), both in peacetime and in war. For much of the next two hundred years, army medical provision was mostly arranged on a regimental basis, with each battalion arranging its own hospital facilities and medical supplies. An element of oversight was provided by the appointment ...
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