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African Trypanosomiasis
African trypanosomiasis is an insect-borne parasitic infection of humans and other animals. Human African trypanosomiasis (HAT), also known as African sleeping sickness or simply sleeping sickness, is caused by the species ''Trypanosoma brucei''. Humans are infected by two types, ''Trypanosoma brucei gambiense'' (TbG) and ''Trypanosoma brucei rhodesiense'' (TbR). TbG causes over 92% of reported cases. Both are usually transmitted by the bite of an infected tsetse fly and are most common in rural areas. Initially, the first stage of the disease is characterized by fevers, headaches, itchiness, and joint pains, beginning one to three weeks after the bite. Weeks to months later, the second stage begins with confusion, poor coordination, numbness, and trouble sleeping. Diagnosis involves detecting the parasite in a blood smear or lymph node fluid. A lumbar puncture is often needed to tell the difference between first- and second-stage disease. Prevention of severe disease in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood Film
A blood smear, peripheral blood smear or blood film is a thin layer of blood smeared on a glass microscope slide and then stained in such a way as to allow the various blood cells to be examined microscopically. Blood smears are examined in the investigation of hematological (blood) disorders and are routinely employed to look for blood parasites, such as those of malaria and filariasis. Preparation A blood smear is made by placing a drop of blood on one end of a slide, and using a ''spreader slide'' to disperse the blood over the slide's length. The aim is to get a region, called a monolayer, where the cells are spaced far enough apart to be counted and differentiated. The monolayer is found in the "feathered edge" created by the spreader slide as it draws the blood forward. The slide is left to air dry, after which the blood is fixed to the slide by immersing it briefly in methanol. The fixative is essential for good staining and presentation of cellular detail. After fixa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Parasitic
Parasitism is a close relationship between species, where one organism, the parasite, lives (at least some of the time) on or inside another organism, the host, causing it some harm, and is adapted structurally to this way of life. The entomologist E. O. Wilson characterised parasites' way of feeding as "predators that eat prey in units of less than one". Parasites include single-celled protozoans such as the agents of malaria, sleeping sickness, and amoebic dysentery; animals such as hookworms, lice, mosquitoes, and vampire bats; fungi such as honey fungus and the agents of ringworm; and plants such as mistletoe, dodder, and the broomrapes. There are six major parasitic strategies of exploitation of animal hosts, namely parasitic castration, directly transmitted parasitism (by contact), trophicallytransmitted parasitism (by being eaten), vector-transmitted parasitism, parasitoidism, and micropredation. One major axis of classification concerns invasiveness: an endopar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Itch
An itch (also known as pruritus) is a sensation that causes a strong desire or reflex to scratch. Itches have resisted many attempts to be classified as any one type of sensory experience. Itches have many similarities to pain, and while both are unpleasant sensory experiences, their behavioral response patterns are different. Pain creates a withdrawal reflex, whereas itches leads to a scratch reflex. Unmyelinated nerve fibers for itches and pain both originate in the skin. Information for them is conveyed centrally in two distinct systems that both use the same nerve bundle and spinothalamic tract. Classification Most commonly, an itch is felt in one place. If it is felt all over the body, then it is called ''generalized itch'' or ''generalized pruritus''. Generalized itch is infrequently a symptom of a serious underlying condition, such as cholestatic liver disease. If the sensation of itching persists for six weeks or longer, then it is called ''chronic itch'' or ''c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Arthralgia
Arthralgia () literally means ' joint pain'. Specifically, arthralgia is a symptom of injury, infection, illness (in particular arthritis), or an allergic reaction to medication Medication (also called medicament, medicine, pharmaceutical drug, medicinal product, medicinal drug or simply drug) is a drug used to medical diagnosis, diagnose, cure, treat, or preventive medicine, prevent disease. Drug therapy (pharmaco .... According to MeSH, the term ''arthralgia'' should only be used when the condition is non-inflammatory, and the term ''arthritis'' should be used when the condition is inflammatory. Causes The causes of ''arthralgia'' are varied and range, from a joints perspective, from degenerative and destructive processes such as osteoarthritis and sports injuries to inflammation of tissues surrounding the joints, such as bursitis. These might be triggered by other things, such as infections or vaccinations. Diagnosis Diagnosis involves interviewing the patie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intermittent Fever
Intermittent fever is a type or pattern of fever in which there is an interval where temperature is elevated for several hours followed by an interval when temperature drops back to normal. This type of fever usually occurs during the course of an infectious disease. Diagnosis of intermittent fever is frequently based on the clinical history but some biological tests like complete blood count and blood culture are also used. In addition radiological investigations like chest X-ray, abdominal ultrasonography can also be used in establishing diagnosis. Intermittent fever in malaria Malaria is a common cause of intermittent fever and it has following types. Quotidian fever Bouts of fever occurring daily (24-hour periodicity) for a few hours, typical of ''Plasmodium falciparum''. Tertian fever Fever occurs after an interval of two days (48-hour periodicity), typical of ''Plasmodium vivax'' and '' Plasmodium ovale''. Quartan fever Fever occurs after an interval of three days ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ulcer
An ulcer is a discontinuity or break in a bodily membrane that impedes normal function of the affected organ. According to Robbins's pathology, "ulcer is the breach of the continuity of skin, epithelium or mucous membrane caused by sloughing out of inflamed necrotic tissue." Common forms of ulcers recognized in medicine include: * Ulcer (dermatology), a discontinuity of the skin or a break in the skin. ** Pressure ulcers, also known as bedsores ** Genital ulcer, an ulcer located on the genital area ** Ulcerative dermatitis, a skin disorder associated with bacterial growth often initiated by self-trauma ** Anal fissure, an ulcer or tear near the anus or within the rectum ** Diabetic foot ulcer, a major complication of the diabetic foot * Callous ulcer, a chronic nonhealing ulcer with hard indurated base and inelastic margins * Corneal ulcer, an inflammatory or infective condition of the cornea * Mouth ulcer, an open sore inside the mouth. ** Aphthous ulcer, a specific ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lymphadenopathy
Lymphadenopathy or adenopathy is a disease of the lymph nodes, in which they are abnormal in size or consistency. Lymphadenopathy of an inflammatory type (the most common type) is lymphadenitis, producing swollen or enlarged lymph nodes. In clinical practice, the distinction between lymphadenopathy and lymphadenitis is rarely made and the words are usually treated as synonymous. Inflammation of the lymphatic vessels is known as lymphangitis. Infectious lymphadenitis affecting lymph nodes in the neck is often called scrofula. Lymphadenopathy is a common and nonspecific sign. Common causes include infections (from minor causes such as the common cold and post-vaccination swelling to serious ones such as HIV/AIDS), autoimmune diseases, and cancer. Lymphadenopathy is frequently idiopathic and self-limiting. Causes Lymph node enlargement is recognized as a common sign of infectious, autoimmune, or malignant disease. Examples may include: * Reactive: acute infection (e.g., ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Animal Trypanosomiasis
Animal trypanosomiasis, also known as nagana and nagana pest, or sleeping sickness, is a disease of non-human vertebrates. The disease is caused by trypanosoma, trypanosomes of several species in the genus ''Trypanosoma'' such as ''Trypanosoma brucei, T. brucei'' (which also infects humans to cause African Sleeping Sickness), and ''Trypanosoma vivax, T. vivax'' which causes nagana in livestock mainly in West Africa, although it has also spread to South America. The trypanosomes infect the blood of the vertebrate host, causing fever, weakness, and lethargy, which lead to weight loss and anemia. In some animals, the disease is fatal if not treated. The trypanosomes are transmitted by tsetse fly, tsetse flies. An interesting feature is the remarkable tolerance to nagana pathology shown by some breeds of cattle, notably the N'Dama – a West African ''Bos taurus'' breed. This contrasts with the susceptibility shown by East African ''Bos indicus, B. indicus'' cattle such as the zebu. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neglected Tropical Disease
Neglected tropical diseases (NTDs) are a diverse group of tropical infections that are common in low-income populations in developing regions of Africa, Asia, and the Americas. They are caused by a variety of pathogens, such as viruses, bacteria, protozoa, and parasitic worms (helminths). These diseases are contrasted with the "big three" infectious diseases (HIV/AIDS, tuberculosis, and malaria), which generally receive greater treatment and research funding. In sub-Saharan Africa, disease burden, the effect of neglected tropical diseases as a group is comparable to that of malaria and tuberculosis. NTD co-infection can also make HIV/AIDS and tuberculosis more deadly. Some treatments for NTDs are relatively inexpensive. For example, praziquantel for schistosomiasis costs about US $0.20 per child per year. Nevertheless, in 2010 it was estimated that control of neglected diseases would require funding of between US$2 billion and $3 billion over the subsequent five to sev ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Congo Basin
The Congo Basin () is the sedimentary basin of the Congo River. The Congo Basin is located in Central Africa, in a region known as west equatorial Africa. The Congo Basin region is sometimes known simply as the Congo. It contains some of the largest tropical rainforests in the world and is an important source of water used in agriculture and energy generation. The rainforest in the Congo Basin is the largest rainforest in Africa and second only to the Amazon rainforest in size, with 300 million hectares compared to the 800 million hectares in the Amazon. Because of its size and diversity the basin's forest is important for mitigating climate change in its role as a carbon sink. However, deforestation and degradation of the ecology by the impacts of climate change may increase stress on the forest ecosystem, in turn making the hydrology of the basin more variable. A 2012 study found that the variability in precipitation caused by climate change will negatively affect economic a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Uganda
Uganda, officially the Republic of Uganda, is a landlocked country in East Africa. It is bordered to the east by Kenya, to the north by South Sudan, to the west by the Democratic Republic of the Congo, to the south-west by Rwanda, and to the south by Tanzania. The southern part includes a substantial portion of Lake Victoria, shared with Kenya and Tanzania. Uganda is in the African Great Lakes region, lies within the Nile basin, and has a varied equatorial climate. , it has a population of 49.3 million, of whom 8.5 million live in the capital and largest city, Kampala. Uganda is named after the Buganda, Buganda kingdom, which encompasses a large portion of the south, including Kampala, and whose language Luganda is widely spoken; the official language is English. The region was populated by various ethnic groups, before Bantu and Nilotic groups arrived around 3,000 years ago. These groups established influential kingdoms such as the Empire of Kitara. The arrival of Arab trade ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Democratic Republic Of The Congo
The Democratic Republic of the Congo (DRC), also known as the DR Congo, Congo-Kinshasa, or simply the Congo (the last ambiguously also referring to the neighbouring Republic of the Congo), is a country in Central Africa. By land area, it is the List of African countries by area, second-largest country in Africa and the List of countries and dependencies by area, 11th-largest in the world. With a population of around 112 million, the DR Congo is the most populous nominally List of countries and territories where French is an official language, Francophone country in the world. Belgian French, French is the official and most widely spoken language, though there are Languages of the Democratic Republic of the Congo, over 200 indigenous languages. The national capital and largest city is Kinshasa, which is also the economic center. The country is bordered by the Republic of the Congo, the Cabinda Province, Cabinda exclave of Angola, and the South Atlantic Ocean to the west; the Cen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
