|
Ruth Shoer Rappaport
Ruth Shoer Rappaport (née Shoer; April 22, 1937 – April 28, 2020) was an American scientist and vaccine researcher. Early life and education Ruth Shoer was born on April 22, 1937, to Jennie (Pearl) Shoer and Irving Shoer. She grew up in Peabody, Massachusetts. She graduated from Peabody High School. Along with her twin sister, Shoer graduated from Vassar College in 1959. She continued her studies at Yale University and earned her Ph.D. in 1967. Career Ruth Shoer Rappaport was the first woman hired as a scientist at Wyeth Laboratories. She worked at Wyeth for four decades and rose to become the senior director of clinical immunology and virology at the company. Her research contributed to the development of vaccines for several diseases such as influenza, HIV, human rotavirus, adenovirus, E. coli, and cholera. Throughout her career, Shoer Rappaport authored dozens of scientific papers. Personal life Shoer Rappaport had two sisters, Patricia Goldman-Rakic, her identi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Née
A birth name is the name of a person given upon birth. The term may be applied to the surname, the given name, or the entire name. Where births are required to be officially registered, the entire name entered onto a birth certificate or birth register may by that fact alone become the person's legal name. The assumption in the Western world is often that the name from birth (or perhaps from baptism or '' brit milah'') will persist to adulthood in the normal course of affairs—either throughout life or until marriage. Some possible changes concern middle names, diminutive forms, changes relating to parental status (due to one's parents' divorce or adoption by different parents). Matters are very different in some cultures in which a birth name is for childhood only, rather than for life. Maiden and married names The French and English-adopted terms née and né (; , ) denote an original surname at birth. The term ''née'', having feminine grammatical gender, can be used ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peabody, Massachusetts
Peabody () is a city in Essex County, Massachusetts, United States. The population was 54,481 at the time of the 2020 United States Census. Peabody is located in the North Shore region of Massachusetts, and is known for its rich industrial history. History The area was long inhabited by Native American people known as the Naumkeag. The area was settled as part of Salem in 1626 by a small group of English colonists from Cape Ann led by Roger Conant. It was subsequently referred to as the Northfields, Salem Farms, and Brooksby. Several area residents were accused of witchcraft during the Salem witch trials of the late 17th century, three of whom were executed ( John Proctor, Giles Corey, and Martha Corey). In 1752, the area was set off from Salem, and incorporated as a district of Danvers. It was referred to as "the South Parish", associated with a church located in present-day Peabody Square. In 1855, the community broke away from Danvers, and was incorporated as the inde ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vassar College
Vassar College ( ) is a private liberal arts college in Poughkeepsie, New York, United States. Founded in 1861 by Matthew Vassar, it was the second degree-granting institution of higher education for women in the United States, closely following Elmira College. It became coeducational in 1969 and now has a gender ratio at the national average. The college is one of the historic Seven Sisters, the first elite women's colleges in the U.S., and has a historic relationship with Yale University, which suggested a merger before they both became coeducational institutions. About 2,450 students attend the college. As of 2021, its acceptance rate is 19%. The college offers B.A. degrees in more than 50 majors and features a flexible curriculum designed to promote a breadth of studies. Student groups at the college include theater and comedy organizations, a cappella groups, club sports teams, volunteer and service groups, and a circus troupe. Vassar College's varsity sports teams, kno ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yale University
Yale University is a private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the third-oldest institution of higher education in the United States and among the most prestigious in the world. It is a member of the Ivy League. Chartered by the Connecticut Colony, the Collegiate School was established in 1701 by clergy to educate Congregational ministers before moving to New Haven in 1716. Originally restricted to theology and sacred languages, the curriculum began to incorporate humanities and sciences by the time of the American Revolution. In the 19th century, the college expanded into graduate and professional instruction, awarding the first PhD in the United States in 1861 and organizing as a university in 1887. Yale's faculty and student populations grew after 1890 with rapid expansion of the physical campus and scientific research. Yale is organized into fourteen constituent schools: the original undergraduate col ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wyeth
Wyeth, LLC was an American pharmaceutical company. The company was founded in Philadelphia, Pennsylvania, in 1860 as ''John Wyeth and Brother''. It was later known, in the early 1930s, as American Home Products, before being renamed to Wyeth in 2002. Its headquarters moved to Collegeville, Pennsylvania and Madison, New Jersey, before they were consolidated with Pfizer's in New York City after the 2009 merger. Most of Wyeth's pharmaceutical assets were acquired by Pfizer in 2009, while its infant and maternal nutrition business was acquired by Nestlé in 2012. Wyeth manufactured over-the-counter drugs (OTCs) Robitussin and the analgesic Advil (ibuprofen) as well as prescription drugs Premarin and Effexor. History 1860–1899 In 1860, pharmacists John (1834–1907) and Frank Wyeth opened a drugstore with a small research lab on Walnut Street in Philadelphia. In 1862, on the suggestion of doctors, they began to manufacture large quantities of commonly ordered medicines ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Influenza
Influenza, commonly known as "the flu", is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptoms begin from one to four days after exposure to the virus (typically two days) and last for about 2–8 days. Diarrhea and vomiting can occur, particularly in children. Influenza may progress to pneumonia, which can be caused by the virus or by a subsequent bacterial infection. Other complications of infection include acute respiratory distress syndrome, meningitis, encephalitis, and worsening of pre-existing health problems such as asthma and cardiovascular disease. There are four types of influenza virus, termed influenza viruses A, B, C, and D. Aquatic birds are the primary source of Influenza A virus (IAV), which is also widespread in various mammals, including humans and pigs. Influenza B virus (IBV) and Influenza C virus (ICV) pri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rotavirus
''Rotavirus'' is a genus of double-stranded RNA viruses in the family ''Reoviridae''. Rotaviruses are the most common cause of diarrhoeal disease among infants and young children. Nearly every child in the world is infected with a rotavirus at least once by the age of five. Immunity develops with each infection, so subsequent infections are less severe. Adults are rarely affected. There are nine species of the genus, referred to as A, B, C, D, F, G, H, I and J. ''Rotavirus A'', the most common species, causes more than 90% of rotavirus infections in humans. The virus is transmitted by the faecal-oral route. It infects and damages the cells that line the small intestine and causes gastroenteritis (which is often called "stomach flu" despite having no relation to influenza). Although rotavirus was discovered in 1973 by Ruth Bishop and her colleagues by electron micrograph images and accounts for approximately one third of hospitalisations for severe diarrhoea in infants and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adenoviridae
Adenoviruses (members of the family ''Adenoviridae'') are medium-sized (90–100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double-stranded DNA genome. Their name derives from their initial isolation from human adenoids in 1953. They have a broad range of vertebrate hosts; in humans, more than 50 distinct adenoviral serotypes have been found to cause a wide range of illnesses, from mild respiratory infections in young children (known as the common cold) to life-threatening multi-organ disease in people with a weakened immune system. Virology Classification This family contains the following genera: * '' Atadenovirus'' * '' Aviadenovirus'' * '' Ichtadenovirus'' * '' Mastadenovirus'' (including all human adenoviruses) * '' Siadenovirus'' * '' Testadenovirus'' Diversity In humans, currently there are 88 human adenoviruses (HAdVs) in seven species (Human adenovirus A to G): * A: 12, 18, 31 * B: 3, 7, 11, 14, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Escherichia Coli
''Escherichia coli'' (),Wells, J. C. (2000) Longman Pronunciation Dictionary. Harlow ngland Pearson Education Ltd. also known as ''E. coli'' (), is a Gram-negative, facultative anaerobic, rod-shaped, coliform bacterium of the genus ''Escherichia'' that is commonly found in the lower intestine of warm-blooded organisms. Most ''E. coli'' strains are harmless, but some serotypes ( EPEC, ETEC etc.) can cause serious food poisoning in their hosts, and are occasionally responsible for food contamination incidents that prompt product recalls. Most strains do not cause disease in humans and are part of the normal microbiota of the gut; such strains are harmless or even beneficial to humans (although these strains tend to be less studied than the pathogenic ones). For example, some strains of ''E. coli'' benefit their hosts by producing vitamin K2 or by preventing the colonization of the intestine by pathogenic bacteria. These mutually beneficial relationships between ''E. col ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cholera
Cholera is an infection of the small intestine by some strains of the bacterium ''Vibrio cholerae''. Symptoms may range from none, to mild, to severe. The classic symptom is large amounts of watery diarrhea that lasts a few days. Vomiting and muscle cramps may also occur. Diarrhea can be so severe that it leads within hours to severe dehydration and electrolyte imbalance. This may result in sunken eyes, cold skin, decreased skin elasticity, and wrinkling of the hands and feet. Dehydration can cause the skin to turn bluish. Symptoms start two hours to five days after exposure. Cholera is caused by a number of types of ''Vibrio cholerae'', with some types producing more severe disease than others. It is spread mostly by unsafe water and unsafe food that has been contaminated with human feces containing the bacteria. Undercooked shellfish is a common source. Humans are the only known host for the bacteria. Risk factors for the disease include poor sanitation, not enough clea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Patricia Goldman-Rakic
Patricia Goldman-Rakic ( ; née Shoer, April 22, 1937 – July 31, 2003) was an American professor of neuroscience, neurology, psychiatry and psychology at Yale University School of Medicine. She pioneered multidisciplinary research of the prefrontal cortex and working memory. Early life and education Patricia Shoer was born in Salem, Massachusetts. Her father, Irving Shoer, was the son of Latvian immigrants and her mother, Jenny Pearl, was a Russian immigrant. She grew up in Peabody, Massachusetts and attended Peabody High School. Goldman-Rakic earned her bachelor's degree cum laude in neurobiology from Vassar in 1959, and her doctorate from the University of California at Los Angeles in experimental Developmental Psychology in 1963."Patricia Goldman-Rakic", Newsmakers, Issue 4. Gale Group, 2002. Reproduced in Biography Resource Center. Farmington Hills, Mich.: Thomson Gale. 2007. http://galenet.galegroup.com/servlet/BioRC After postdoctoral positions at UCLA and New Yor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Philadelphia
Philadelphia, often called Philly, is the largest city in the Commonwealth of Pennsylvania, the sixth-largest city in the U.S., the second-largest city in both the Northeast megalopolis and Mid-Atlantic regions after New York City. Since 1854, the city has been coextensive with Philadelphia County, the most populous county in Pennsylvania and the urban core of the Delaware Valley, the nation's seventh-largest and one of world's largest metropolitan regions, with 6.245 million residents . The city's population at the 2020 census was 1,603,797, and over 56 million people live within of Philadelphia. Philadelphia was founded in 1682 by William Penn, an English Quaker. The city served as capital of the Pennsylvania Colony during the British colonial era and went on to play a historic and vital role as the central meeting place for the nation's founding fathers whose plans and actions in Philadelphia ultimately inspired the American Revolution and the nation's inde ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
