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Wyeth
Wyeth, LLC was an American pharmaceutical company. The company was founded in Philadelphia, Pennsylvania, in 1860 as ''John Wyeth and Brother''. It was later known, in the early 1930s, as American Home Products, before being renamed to Wyeth in 2002. Its headquarters moved to Collegeville, Pennsylvania and Madison, New Jersey, before they were consolidated with Pfizer's in New York City after the 2009 merger. Most of Wyeth's pharmaceutical assets were acquired by Pfizer in 2009, while its infant and maternal nutrition business was acquired by Nestlé in 2012. Wyeth manufactured over-the-counter drugs (OTCs) Robitussin and the analgesic Advil (ibuprofen) as well as prescription drugs Premarin and Effexor. History 1860–1899 In 1860, pharmacists John (1834–1907) and Frank Wyeth opened a drugstore with a small research lab on Walnut Street in Philadelphia. In 1862, on the suggestion of doctors, they began to manufacture large quantities of commonly ordered medicines ...
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John Wyeth
John Wyeth (1770–1858) was a printer in Harrisburg, Pennsylvania who is best-known for printing ''Wyeth's Repository of Sacred Music, Part Second'' (Harrisburg, PA: 1813), which marks an important transition in American music. Like the original ''Repository'' of 1810, ''Part Second'' used the four-shape system of Little and Smith in ''The Easy Instructor'' (Philadelphia, PA: 1801) to appeal to a wider audience; but its pioneering inclusion American folk tunes influenced all subsequent folk hymn, camp meeting, and shape note collections. Musicologist Warren Steel sees ''Wyeth's Repository of Sacred Music, Part Second'' as marking "the end of the age of New England composer-compilers (1770-1810) and the beginning of the age of southern collector-compilers (1816-1860)."David Warren Steel, "John Wyeth and the Development of Southern Folk Hymnody", ''Music from the Middle Ages Through the 20th Century: Essays in Honor of Gwynn McPeek,'' Carmelo P. Comberiati and Matthew C. Steel, eds. ...
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Nestlé Wyeth Nutrition
Nestlé-Wyeth Nutrition (formerly owned by Pfizer after the acquisition of Wyeth in 2009) provides food products to meet the needs of infants, young children and adults. Through scientific research, they claim to help nourish children when breastfeeding is not an option. Wyeth Nutrition started in 1915 when Henry Grestberger manufactured the first formula patterned after breast milk called SMA (synthetic milk adaptive). Wyeth Pharmaceuticals, formerly Wyeth-Ayerst Laboratories, is the original company founded by the Wyeth brothers, originally known as John Wyeth and Brother. They focused on the research, development, and marketing of prescription drugs. The pharmaceuticals division was further subdivided into five subdivisions: Wyeth Research, Prescription Products, Biotech, Vaccines, and Nutritionals. Wyeth's research and development director Robert R. Ruffolo, Jr, Robert Ruffolo was quoted in ''The New York Times'' about the firm's efforts to develop new drugs. Acquisition by Nes ...
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Pfizer
Pfizer Inc. ( ) is an American multinational pharmaceutical and biotechnology corporation headquartered on 42nd Street in Manhattan, New York City. The company was established in 1849 in New York by two German entrepreneurs, Charles Pfizer (1824–1906) and his cousin Charles F. Erhart (1821–1891). Pfizer develops and produces medicines and vaccines for immunology, oncology, cardiology, endocrinology, and neurology. The company has several blockbuster drugs or products that each generate more than billion in annual revenues. In 2020, 52% of the company's revenues came from the United States, 6% came from each of China and Japan, and 36% came from other countries. Pfizer was a component of the Dow Jones Industrial Average stock market index from 2004 to August 2020. The company ranks 64th on the Fortune 500 and 49th on the Forbes Global 2000. History 1849–1950: Early history Pfizer was founded in 1849 by Charles Pfizer and Charles F. Erhart, two cousins who had i ...
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Premarin
Conjugated estrogens (CEs), or conjugated equine estrogens (CEEs), sold under the brand name Premarin among others, is an estrogen medication which is used in menopausal hormone therapy and for various other indications. It is a mixture of the sodium salts of estrogen conjugates found in horses, such as estrone sulfate and equilin sulfate. CEEs are available in the form of both natural preparations manufactured from the urine of pregnant mares and fully chemical synthesis, synthetic replications of the natural preparations. They are formulated both alone and in combination with progestins such as medroxyprogesterone acetate. CEEs are usually taken oral administration, by mouth, but can also be given by topical medication, application to the skin or vaginal administration, vagina as a cream (pharmaceutical), cream or by intravenous injection, injection into a blood vessel or intramuscular injection, muscle. Side effects of CEEs include breast pain, breast tenderness and mammopla ...
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Enbrel
Etanercept, sold under the brand name Enbrel among others, is a biologic medical product that is used to treat autoimmune diseases by interfering with tumor necrosis factor (TNF), a soluble inflammatory cytokine, by acting as a TNF inhibitor. It has U.S. Food and Drug Administration (FDA) approval to treat rheumatoid arthritis, juvenile idiopathic arthritis and psoriatic arthritis, Psoriasis, plaque psoriasis and ankylosing spondylitis. Tumor necrosis factor alpha (TNFα) is the "master regulator" of the inflammatory (immune) response in many organ systems. Autoimmune diseases are caused by an overactive immune response. Etanercept has the potential to treat these diseases by inhibiting TNF-alpha. Etanercept is a fusion protein produced by recombinant DNA. It fuses the TNF receptor to the constant end of the IgG1 antibody. First, the developers isolated the DNA sequence that codes the human gene for soluble CD120, TNF receptor 2, which is a receptor that binds to tumor necrosis fac ...
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Effexor
Venlafaxine, sold under the brand name Effexor among others, is an antidepressant medication of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. It is used to treat major depressive disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder. It may also be used for chronic pain. It is taken by mouth. It is also available as the salt venlafaxine besylate in an extended-release formulation (Venbysi XR). Common side effects include loss of appetite, constipation, dry mouth, dizziness, sweating, insomnia, drowsiness and sexual problems. Severe side effects include an increased risk of suicide, mania, and serotonin syndrome. Antidepressant withdrawal syndrome may occur if stopped. There are concerns that use during the later part of pregnancy can harm the baby. How it works is not entirely clear, but it seems to be related to the potentiation of the activity of some neurotransmitters in the brain. Venlafaxine was approved for medical use in t ...
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Robitussin
Cold medicines are a group of medications taken individually or in combination as a treatment for the symptoms of the common cold and similar conditions of the upper respiratory tract. The term encompasses a broad array of drugs, including analgesics, antihistamines and decongestants, among many others. It also includes drugs which are marketed as cough suppressants or antitussives, but their effectiveness in reducing cough symptoms is unclear or minimal. While they have been used by 10% of American children in any given week, they are not recommended in Canada or the United States in children six years or younger because of lack of evidence showing effect and concerns of harm. In 2020, one version containing codeine and guaifenesin was the 377th most commonly prescribed medication in the United States with more than 400thousand prescriptions. Types There are a number of different cough and cold medications, which may be used for various coughing symptoms. The commercially a ...
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Nestlé
Nestlé S.A. (; ; ) is a Switzerland, Swiss multinational food and drink processing conglomerate corporation headquartered in Vevey, Vaud, Switzerland. It is the largest publicly held food company in the world, measured by revenue and other metrics, since 2014."Nestlé's Brabeck: We have a "huge advantage" over big pharma in creating medical foods"
, ''CNN Money'', 1 April 2011
It ranked No. 64 on the Fortune Global 500, ''Fortune'' Global 500 in 2017 and No. 33 in the 2016 edition of the ''Forbes'' Global 2000 list of largest public companies. Nestlé's products include baby food (some including human milk oligosaccharides), medical food, bottled water, breakfast cereals, coffee and tea, confectionery, ...
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Pharmaceutical Company
The pharmaceutical industry discovers, develops, produces, and markets drugs or pharmaceutical drugs for use as medications to be administered to patients (or self-administered), with the aim to cure them, vaccinate them, or alleviate symptoms. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy using drug testing and marketing of drugs. The global pharmaceuticals market produced treatments worth $1,228.45 billion in 2020 and showed a compound annual growth rate (CAGR) of 1.8%. History Mid-1800s – 1945: From botanicals to the first synthetic drugs The modern era of pharmaceutical industry began with local apothecaries that expanded from their traditional role of distributing botanical drugs such as morphine and quinine to wholesale manufacture in the mid-1800s, and from discoveries resulting from applied research. Intentional ...
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Collegeville, Pennsylvania
Collegeville is a borough in Montgomery County, Pennsylvania, a suburb outside of Philadelphia on Perkiomen Creek. Collegeville was incorporated in 1896. It is the location of Ursinus College which opened in 1869. The population was 5,089 at the 2010 census. History The area which is present day Collegeville was part of the original William Penn purchase of "All the land lying on the Pahkehoma" in 1684. In 1799, Perkiomen Bridge was constructed using funds raised from a special lottery approved by the Pennsylvania Legislature. When the first post office in this area was established in 1847, it was called Perkiomen Bridge. In 1832, the first school for primary and secondary students was established and it was later renamed Freeland Public School in 1844. In 1848, Henry A. Hunsicker built the "Freeland Seminary of Perkiomen Bridge." Village around the school became known as Freeland. In 1851, Abraham Hunsicker established the Pennsylvania Female College near present-day Glen ...
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Madison, New Jersey
Madison is a borough in Morris County, in the U.S. state of New Jersey. As of the 2020 United States census, the population was 16,937. Located along the Morris & Essex Lines, it is noted for Madison's historic railroad station becoming one of America's first commuter railroads, attracting well-to-do families from nearby Manhattan. It remains a popular commuter town for residents who work in New York City. The community maintains a population of nearly 18,000 residents. It is known as ''"The Rose City"'' and was named in honor of President James Madison.Caldwell, Dave"Living in Madison, N.J.; A Town Right Out of Central Casting" ''The New York Times'', June 15, 2008. Accessed August 12, 2012. "Madison, named after President James Madison, was nicknamed the Rose City because of a 19th-century rose-growing industry started by wealthy residents drawn to Madison by its location on the Morris & Essex train line." Madison was ranked 33rd in ''Money'' Magazine's 2011 ranking of the ...
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Analgesic
An analgesic drug, also called simply an analgesic (American English), analgaesic (British English), pain reliever, or painkiller, is any member of the group of drugs used to achieve relief from pain (that is, analgesia or pain management). It is typically used to induce cooperation with a medical procedure. Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in some instances eliminate, sensation, although analgesia and anesthesia are neurophysiologically overlapping and thus various drugs have both analgesic and anesthetic effects. Analgesic choice is also determined by the type of pain: For neuropathic pain, traditional analgesics are less effective, and there is often benefit from classes of drugs that are not normally considered analgesics, such as tricyclic antidepressants and anticonvulsants. Various analgesics, such as many NSAIDs, are available over the counter in most countries, whereas various others are prescription drugs owing ...
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