Novartis Medal And Prize
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Novartis Medal And Prize
The Portland Press Excellence in Science Award was an annual award instituted in 1964 to recognize notable research in any branch of biochemistry undertaken in the UK or Republic of Ireland. It was initially called the CIBA Medal and Prize, then the Novartis Medal and Prize. The prize consists of a medal and a £3000 cash award. The winner is invited to present a lecture at a Society conference and submit an article to one of the Society's publications. Notable recipients include the Nobel laureates John E. Walker, Paul Nurse, Sydney Brenner, César Milstein, Peter D. Mitchell, Rodney Porter, and John Cornforth. The Novartis Medal and Prize was last presented in 2019 and will be replaced from 2021 by the Portland Press Excellence in Science Award. Portland Press is the publishing arm of the Biochemical Society. Recipients SourceBiochemical Society ; Novartis Medal and Prize * 2021: Bart Vanhaesebroeck * 2019: Caroline Dean * 2018: Laurence Pearl * 2017: Doreen Cantrell ...
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Biochemistry
Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all areas of the life sciences are being uncovered and developed through biochemical methodology and research. Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis which allows biological molecules to give rise to the processes that occur within living cells and between cells,Karp (2009), p. 2. in turn relating greatly to the understanding of tissues and organs, as well as organism structure and function.Miller (2012). p. 62. Biochemistry is closely related to molecular biology, which is the study of the molecular mechanisms of biological phenomena.As ...
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Adrian Bird
Sir Adrian Peter Bird, (born 3 July 1947) is a British geneticist and Buchanan Professor of Genetics at the University of Edinburgh. Bird has spent much of his academic career in Edinburgh, from receiving his PhD in 1970 to working at the MRC Mammalian Genome Unit and later serving as director of the Wellcome Trust Centre for Cell Biology. His research focuses on understanding DNA methylation and CpG islands, and their role in diseases such as Rett syndrome. Education and early life Bird was born in Rowley Regis near Wolverhampton, England, but from age 4 lived in the town of Kidderminster, near Birmingham. He attended a grammar school in Hartlebury, achieving grades CCD for his A-level results. Whilst at school, Bird played cricket and hockey for a local team. Bird received his PhD from the University of Edinburgh in 1970 for research supervised by Max Birnstiel, following undergraduate study of Biochemistry at the University of Sussex. Career and research Following his P ...
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Tom Blundell
Sir Thomas Leon Blundell, (born 7 July 1942) is a British biochemist, structural biologist, and science administrator. He was a member of the team of Dorothy Hodgkin that solved in 1969 the first structure of a protein hormone, insulin. Blundell has made contributions to the structural biology of polypeptide hormones, growth factors, receptor activation, signal transduction, and DNA double-strand break repair, subjects important in cancer, tuberculosis, and familial diseases. He has developed software for protein modelling and understanding the effects of mutations on protein function, leading to new approaches to structure-guided and Fragment-based lead discovery. In 1999 he co-founded the oncology company Astex Therapeutics, which has moved ten drugs into clinical trials. Blundell has played central roles in restructuring British research councils and, as President of the UK Science Council, in developing professionalism in the practice of science. Education Born in Bri ...
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Philip Cohen (British Biochemist)
Sir Philip Cohen (born 22 July 1945) is a British researcher, academic and Royal Medal winner based at the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences at the University of Dundee. During the 1990s he was the world's third most cited professor (and the second most cited in the fields of biology and biochemistry) and has been described by Professor Garry Taylor of the University of St Andrews as "one of the world’s top scientists". and by Professor Sir Peter Downes as "arguably the UK's leading biochemist and an iconic figure in UK science". As of 2008 he has written over 470 peer-reviewed papers and given over 250 invited lectures in 33 countries, and has been repeatedly linked to a move of biotechnology companies to Dundee and the economic regeneration that came with it, to the point where 15% of the local economy is derived from biotech companies and their employees. His work has also seen Dundee attracting some of th ...
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Terence Rabbitts
Terence Howard Rabbitts FRS FMedSci is currently Professor of Molecular Immunology at the Institute of Cancer Research, London. Education He was educated at John Ruskin Grammar School, the University of East Anglia where he graduated with a BSc with first class honours in Biological Sciences, and subsequently completed his PhD at the National Institute for Medical Research, Mill Hill, London. Career & Research Terry Rabbitts obtained a BSc at the School of Biological Sciences, University of East Anglia where he studied molecular genetics, obtaining a First Class Honours. He obtained a PhD at the National Institute for Medical Research, Mill Hill (NIMR) supervised by Thomas Work (at NIMR) and by Ken Murray (at the University of Edinburgh) on mitochondrial nucleic acid homogeneity. At NIMR, he became interested in molecular immunology from Peter Medawar's work on immune tolerance. He worked as a post-doctoral fellow in Cesar Milstein's group at thMRC Laboratory of Molecular Bio ...
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Chris Higgins (academic)
Christopher Francis Higgins (born 24 June 1955) is a British molecular biologist, geneticist, academic and scientific advisor. He was the Vice-Chancellor of Durham University from 2007 to 2014. He took early retirement on 30 September 2014, following a discussion at Senate on limiting the powers of the Vice Chancellor. He was previously the director of the MRC Clinical Sciences Centre and Head of Division in the Faculty of Medicine at Imperial College London. Early life Higgins was born on 24 June 1955 in Cambridge, England. He studied botany at Grey College, Durham University, graduating with a first class degree in 1976. He was awarded a PhD in 1979 for his study of peptide transporters in the embryos of germinating Barley. Working at University of Dundee, his focus turned to genetics and cell biology. Career Higgins was appointed Nuffield Professor of Clinical Biochemistry at the University of Oxford. He has published over 200 papers in leading scientific journals like '' ...
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Ronald Laskey
Ronald Alfred Laskey (born 26 January 1945) is a British cell biologist and cancer researcher. Career and research Laskey was the Charles Darwin Professor of Embryology at the University of Cambridge. In 1991, he co-founded the Wellcome Trust/Cancer Research Campaign Institute (now known as the Wellcome Trust/ Cancer Research UK Gurdon Institute), along with five other senior scientists including Professor Sir John Gurdon. In 2001, he founded the Medical Research Council Cancer Cell Unit in 2001, and was Director of the Unit until 2010. Laskey is also a Fellow of Darwin College, Cambridge. Awards and honours Laskey was appointed Commander of the British Empire (CBE) in the 2011 New Year Honours. Other significant honours include the Royal Society Royal Medal, for his "pivotal contributions to our understanding of the control of DNA replication and nuclear protein transport, which has led to a novel screening method for cancer diagnosis", and the Cancer Research UK Lifetime ...
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Richard Perham
Richard Nelson Perham, FRS, FMedSci, FRSA (27 April 1937 – 14 February 2015), was Professor of biochemistry at the University of Cambridge, and Master of St John's College, Cambridge 2004–07. He was also editor-in-chief of ''FEBS Journal'' (Federation of European Biochemical Societies) from 1998 to 2013. Education Perham attended Latymer Upper School, then St John's College, Cambridge, where he completed his MA (Cantab), PhD and ScD. Perham then went on to become a MRC scholar at Laboratory of Molecular Biology (LMB), also at Cambridge. Research and career Perham was known for his contributions to the chemistry of proteins in multimeric assemblies. Societies Perham was a member of the following organisations and societies: * 1965 Biochemical Society member * 1983 EMBO Member * 1986 Royal Institution for Great Britain member * 1992 Academia Europaea member Awards and fellowships His awards include: * 1971 (EMBO) fellowship Max Planck Institute for Medical Research ...
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Christopher Marshall (doctor)
Christopher John Marshall FRS FMedSci (19 January 1949 – 8 August 2015) was a British scientist who worked as director of the Division for Cancer Biology at the Institute of Cancer Research. Marshall was distinguished for research in the field of tumour cell signalling. His track record includes the discovery of the ''N-Ras'' oncogene , the identification of farnesylation of Ras proteins, and the discovery that Ras signals through the MAPK/ERK pathway. These findings have led to therapeutic development of inhibitors of Ras farnesylation, MEK and B-Raf. Early life Marshall was born in Birmingham, UK, and educated at the King Henry VIII School, Coventry. He then studied Natural Sciences at the University of Cambridge followed by a DPhil in cell biology at the University of Oxford. His graduate studies were followed by post-doctoral work at the Imperial Cancer Research Fund laboratories at Lincoln's Inn Fields (now part of the Francis Crick Institute) in London and th ...
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Kiyoshi Nagai
Kiyoshi Nagai (June 25, 1949 – September 27, 2019) was a Japanese structural biologist at the MRC Laboratory of Molecular Biology Cambridge, UK. He was known for his work on the mechanism of RNA splicing and structures of the spliceosome. Education Nagai studied at Osaka University and earned a Doctor of Philosophy under the supervision of Hideki Morimoto working on the allosteric effect in hemoglobin. Career and research In 1981 Nagai moved to the MRC Laboratory of Molecular Biology where he worked as a post-doc with Max Perutz on overproduction of eukaryotic proteins in ''E. coli.'' He produced recombinant hemoglobin and studied its properties and evolution by crystallography and mutagenesis. In 1987 he became a tenured group leader at the LMB and was joint head of the Division of Structural Studies from 2000 to 2010. He was appointed fellow of Darwin College, Cambridge in 1993. In 1990 his group solved the first structure of an RRM (RNA recognition motif) protein, U1 ...
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Michael Neuberger
Michael Samuel Neuberger FRS FMedSci (2 November 1953 – 26 October 2013) was a British biochemist and immunologist. Biography Born in Kensington, Michael Samuel Neuberger was the fourth of five children of Albert Neuberger and Lilian Ida (née Dreyfus). He was educated at Westminster School and Trinity College, Cambridge, from where he graduated with a first class honours degree in Natural Sciences in 1974. Neuberger then joined Brian Hartley at Imperial College to study for his PhD. During this time, and at Hartley’s suggestion, he visited the South African biologist Sydney Brenner at the Laboratory of Molecular Biology (LMB) in Cambridge. Their discussions drew Neuberger back to the LMB in 1980 and he remained there for the rest of his career, eventually becoming its deputy director. César Milstein at the LMB recommended that Neuberger spent some time studying immunology with Klaus Rajewsky at the University of Cologne; he spent 18 months there, after his PhD. Neuberg ...
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Iain Donald Campbell
Iain Donald Campbell (24 April 1941 – 5 March 2014) was a Scottish biophysicist and academic. He was Professor of Structural Biology at the University of Oxford from 1992 to 2009. Early life and education Campbell was born on 24 April 1941 in Blackford, Perth and Kinross, Scotland. He was the son of Daniel Campbell and Catherine Campbell (née Lauder). He was educated at Perth Academy, a state school in Perth. He went on to study physics at the University of St Andrews, graduating in 1963. He remained at St Andrews to undertake post-graduate research and completed his Doctor of Philosophy (PhD) degree in physics. His doctoral advisor was Dirk Bijl, and he undertook research under John F. Allen. Career and research Campbell worked briefly at the University of Bradford before moving to the Physical and Theoretical Chemistry Laboratory at the University of Oxford in South Parks Road, Oxford, in 1967, to work with the chemist Sir Rex Richards. He was appointed a Fellow of S ...
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