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Karl Barry Sharpless
Karl Barry Sharpless (born April 28, 1941) is an American chemist and a two-time Nobel laureate in Chemistry known for his work on stereoselective reactions and click chemistry. Sharpless was awarded half of the 2001 Nobel Prize in Chemistry "for his work on chirally catalysed oxidation reactions", and one third of the 2022 prize, jointly with Carolyn R. Bertozzi and Morten P. Meldal, "for the development of click chemistry and bioorthogonal chemistry". Sharpless is the fifth person (in addition to two organizations), to have twice been awarded a Nobel prize, along with Marie Curie, John Bardeen, Linus Pauling and Frederick Sanger, and the third to have been awarded two prizes in the same discipline (after Bardeen and Sanger). Early life and education Sharpless was born April 28, 1941, in Philadelphia, Pennsylvania. His childhood was filled with summers at his family cottage on the Manasquan River in New Jersey. This is where Sharpless developed a love for fishing that he wo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Philadelphia
Philadelphia, often called Philly, is the largest city in the Commonwealth of Pennsylvania, the sixth-largest city in the U.S., the second-largest city in both the Northeast megalopolis and Mid-Atlantic regions after New York City. Since 1854, the city has been coextensive with Philadelphia County, the most populous county in Pennsylvania and the urban core of the Delaware Valley, the nation's seventh-largest and one of world's largest metropolitan regions, with 6.245 million residents . The city's population at the 2020 census was 1,603,797, and over 56 million people live within of Philadelphia. Philadelphia was founded in 1682 by William Penn, an English Quaker. The city served as capital of the Pennsylvania Colony during the British colonial era and went on to play a historic and vital role as the central meeting place for the nation's founding fathers whose plans and actions in Philadelphia ultimately inspired the American Revolution and the nation's inde ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stanford University
Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is considered among the most prestigious universities in the world. Stanford was founded in 1885 by Leland and Jane Stanford in memory of their only child, Leland Stanford Jr., who had died of typhoid fever at age 15 the previous year. Leland Stanford was a U.S. senator and former governor of California who made his fortune as a railroad tycoon. The school admitted its first students on October 1, 1891, as a coeducational and non-denominational institution. Stanford University struggled financially after the death of Leland Stanford in 1893 and again after much of the campus was damaged by the 1906 San Francisco earthquake. Following World War II, provost of Stanford Frederick Terman inspired and supported faculty and graduates' entrepreneu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Morten P
Morten is a common given name in Norway and Denmark. Approximately 22,138 have this name as a given name in Norway and about 52 people have it as a surname. Notable people with the name include: *Morten Abel, Norwegian singer *Morten Andersen, Danish kicker in American football *Morten Arnfred, Danish film director and screenwriter * Morten Berglia, Norwegian orienteering competitor * Morten Berre, Norwegian footballer *Morten Bertolt, Danish footballer * Morten Bisgaard, Danish footballer *Morten Bo, Danish photographer *Morten Breum, Danish DJ and producer known by his mononym Morten * Morten Bruun, Danish football player * Morten Brørs, Norwegian cross-country skier * Morten Børup, Danish educator *Morten Stig Christensen, Danish handball player, TV host and TV executive * Morten Daland, Norwegian handball player * Morten Djupvik, Norwegian show jumping competitor * Morten Dons, Danish racing driver *Morten Eriksen, Norwegian footballer *Morten Finstad, Norwegian ice hockey pla ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carolyn R
Carolyn is a female given name, a variant of Caroline. Other spellings include Karolyn, Carolyne, Carolynn or Carolynne. Caroline itself is one of the feminine forms of Charles. List of Notable People * Carolyn Bennett (born 1950), Canadian politician *Carolyn Bertozzi (born 1966), American chemist and Nobel laureate *Carolyn Bessette-Kennedy (1966–1999), wife of John F. Kennedy, Jr. *Carolyn Brown (choreographer) (born 1927), American dancer, choreographer, and writer *Carolyn Brown (newsreader), English newsreader *Carolyn Cassady (1923–2013), American writer and wife of Neal Cassady *C. J. Cherryh (Carolyn Janice Cherryh; born 1942), American science fiction and fantasy writer *Carolyn Chiechi (born 1943), judge of the United States Tax Court *Carolyn Cooper (born 1959), Jamaican author and literary scholar * Carolyn Davidson, several people * Carolyn Eaton, murder victim * Carolyn Fe, Filipina singer and actress *Carolyn Forché (born 1950), American poet, editor, transl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Click Chemistry
In chemical synthesis, click chemistry is a class of biocompatible small molecule reactions commonly used in bioconjugation, allowing the joining of substrates of choice with specific biomolecules. Click chemistry is not a single specific reaction, but describes a way of generating products that follow examples in nature, which also generates substances by joining small modular units. In many applications, click reactions join a biomolecule and a reporter molecule. Click chemistry is not limited to biological conditions: the concept of a "click" reaction has been used in chemoproteomic, pharmacological, and various biomimetic applications. However, they have been made notably useful in the detection, localization and qualification of biomolecules. Click reactions occur in one pot, are not disturbed by water, generate minimal and inoffensive byproducts, and are "spring-loaded"—characterized by a high thermodynamic driving force that drives it quickly and irreversibly to high yi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stereoselective Reactions
Enantioselective synthesis, also called asymmetric synthesis, is a form of chemical synthesis. It is defined by IUPAC as "a chemical reaction (or reaction sequence) in which one or more new elements of chirality are formed in a substrate molecule and which produces the stereoisomeric (enantiomeric or diastereomeric) products in unequal amounts." Put more simply: it is the synthesis of a compound by a method that favors the formation of a specific enantiomer or diastereomer. Enantiomers are stereoisomers that have opposite configurations at every chiral center. Diastereomers are stereoisomers that differ at one or more chiral centers. Enantioselective synthesis is a key process in modern chemistry and is particularly important in the field of pharmaceuticals, as the different enantiomers or diastereomers of a molecule often have different biological activity. Overview Many of the building blocks of biological systems such as sugars and amino acids are produced exclusively as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Nobel Laureates In Chemistry
The Nobel Prize in Chemistry ( sv, Nobelpriset i kemi) is awarded annually by the Royal Swedish Academy of Sciences to scientists in the various fields of chemistry. It is one of the five Nobel Prizes established by the 1895 will of Alfred Nobel, who died in 1896. These prizes are awarded for outstanding contributions in chemistry, physics, literature, peace, and physiology or medicine. As dictated by Nobel's will, the award is administered by the Nobel Foundation and awarded by the Royal Swedish Academy of Sciences. The first Nobel Prize in Chemistry was awarded in 1901 to Jacobus Henricus van 't Hoff, of the Netherlands. Each recipient receives a medal, a diploma and a monetary award prize that has varied throughout the years. In 1901, van 't Hoff received 150,782 SEK, which is equal to 7,731,004 SEK in December 2007. The award is presented in Stockholm at an annual ceremony on 10 December, the anniversary of Nobel's death. At least 25 laureates have received the Nobel Pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemist
A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties. Chemists carefully describe the properties they study in terms of quantities, with detail on the level of molecules and their component atoms. Chemists carefully measure substance proportions, chemical reaction rates, and other chemical properties. In Commonwealth English, pharmacists are often called chemists. Chemists use their knowledge to learn the composition and properties of unfamiliar substances, as well as to reproduce and synthesize large quantities of useful naturally occurring substances and create new artificial substances and useful processes. Chemists may specialize in any number of subdisciplines of chemistry. Materials scientists and metallurgists share much of the same education and skills with chemists. The work of chemists is often related to the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hartmuth Kolb
Hartmuth Christian Kolb (born August 10, 1964) is a German chemist. He is considered one of the founders of click chemistry. Early life and career After graduating from high school in Marsberg in 1983, Kolb studied at the University of Hanover. He received his doctorate as an academic student of Steven Ley at Imperial College London with a thesis on preparative organic chemistry (''Synthesis of the decalin fragment of azadirachtin''). As a postdoctoral fellow he worked with Barry Sharpless at the Scripps Research Institute in La Jolla, California. He then worked in the research department of Ciba-Geigy in Basel from 1993 to 1997 before taking up a managerial position at Coelacanth Corporation, founded by Sharpless and A. Bader in Princeton, New Jersey. Coelacanth was eventually acquired by Lexicon Pharmaceuticals. In 2002, Kolb obtained an associate professorship in the Department of Chemistry at the Scripps Research Institute. Kolb later obtained a professorship at the Univ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eugene Van Tamelen
Eugene Earle van Tamelen (July 20, 1925 – December 12, 2009) was an organic chemist who is especially recognized for his contributions to bioorganic chemistry. van Tamelen published five papers while an undergraduate at Hope College. He conducted graduate work at Harvard University, receiving his doctorate in 1950 with Gilbert Stork as his advisor. He began his academic career at the University of Wisconsin, later joining the faculty of Stanford University, where he spent the majority of his career. Among his many students was Nobelist K. Barry Sharpless. He led a team who were the first persons to achieve the total synthesis of yohimbine. He pioneered in what is today called biomimetic synthesis. He was the first to identify squalene oxide as a precursor in the biosynthesis of cholesterol. Van Tamelen was also the first to synthesise Dewar benzene. He developed a system for nitrogen fixation using titanocene. van Tamelen was also the owner of the first Marshall Erdm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Master Of Science
A Master of Science ( la, Magisterii Scientiae; abbreviated MS, M.S., MSc, M.Sc., SM, S.M., ScM or Sc.M.) is a master's degree in the field of science awarded by universities in many countries or a person holding such a degree. In contrast to the Master of Arts degree, the Master of Science degree is typically granted for studies in sciences, engineering and medicine and is usually for programs that are more focused on scientific and mathematical subjects; however, different universities have different conventions and may also offer the degree for fields typically considered within the humanities and social sciences. While it ultimately depends upon the specific program, earning a Master of Science degree typically includes writing a thesis. The Master of Science degree was first introduced at the University of Michigan in 1858. One of the first recipients of the degree was De Volson Wood, who was conferred a Master of Science degree at the University of Michigan in 1859. Al ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bachelor Of Arts
Bachelor of arts (BA or AB; from the Latin ', ', or ') is a bachelor's degree awarded for an undergraduate program in the arts, or, in some cases, other disciplines. A Bachelor of Arts degree course is generally completed in three or four years, depending on the country and institution. * Degree attainment typically takes four years in Afghanistan, Armenia, Azerbaijan, Bangladesh, Brazil, Brunei, China, Egypt, Ghana, Greece, Georgia, Hong Kong, Indonesia, Iran, Iraq, Ireland, Japan, Kazakhstan, Kenya, Kuwait, Latvia, Lebanon, Lithuania, Mexico, Malaysia, Mongolia, Myanmar, Nepal, Netherlands, Nigeria, Pakistan, the Philippines, Qatar, Russia, Saudi Arabia, Scotland, Serbia, South Korea, Spain, Sri Lanka, Taiwan, Thailand, Turkey, Ukraine, the United States and Zambia. * Degree attainment typically takes three years in Albania, Australia, Bosnia and Herzegovina, the Caribbean, Iceland, India, Israel, Italy, New Zealand, Norway, South Africa, Switzerland, the Canadian province of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
