James Francis Tait
James Francis Tait (1926-2014) was an English physicist and endocrinologist. He worked with his wife, Sylvia Agnes Sophia Tait from 1948 until her death in 2003, a partnership described by the Dictionary of National Biography, Oxford Dictionary of National Biography as "one of the most successful examples of husband-wife collaboration." Together, they discovered and identified the hormone aldosterone. Early life Tait was born in Stockton on Tees in 1926, the son of Herbert and Constance Tait (née Brotherton). His parents ran a small grocery shop, but his father died when he was 10. Tait attended Queen Elizabeth Sixth Form College, Darlington Queen Elizabeth 1 Grammar School, where he took Physics, Chemistry, Maths and English Literature for the Higher School Certificate (United Kingdom), Higher School Certificate. He went to Leeds University to read Physics, graduating in 1945. He joined Whiddington's research group at Leeds. completing his PhD thesis entitled ''The energy dist ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Endocrinologist
Endocrinology (from ''endocrine'' + '' -ology'') is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones. It is also concerned with the integration of developmental events proliferation, growth, and differentiation, and the psychological or behavioral activities of metabolism, growth and development, tissue function, sleep, digestion, respiration, excretion, mood, stress, lactation, movement, reproduction, and sensory perception caused by hormones. Specializations include behavioral endocrinology and comparative endocrinology. The endocrine system consists of several glands, all in different parts of the body, that secrete hormones directly into the blood rather than into a duct system. Therefore, endocrine glands are regarded as ductless glands. Hormones have many different functions and modes of action; one hormone may have several effects on different target organs, and, conversely, one target org ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tadeus Reichstein
Tadeusz Reichstein (20 July 1897 – 1 August 1996) was a Polish-Swiss chemist and the Nobel Prize in Physiology or Medicine laureate (1950), which was awarded for his work on the isolation of cortisone. Early life Reichstein was born into a Polish-Jewish family at Włocławek, Russian Empire. His parents were Gastawa (Brockmann) and Izydor Reichstein. He spent his early childhood at Kiev, where his father was an engineer. He began his education at boarding-school in Jena, Germany and arrived in Basel, Switzerland at the age of 8. Career Reichstein studied under Hermann Staudinger during the latter's brief stint at the Technical University of Karlsruhe. It was here that he met Leopold Ruzicka, also a doctoral student. In 1933, working in Zürich, Switzerland, at the ETHZ chemical laboratories of Ruzicka, Reichstein succeeded, independently of Sir Norman Haworth and his collaborators in the United Kingdom, in synthesizing vitamin C (ascorbic acid) in what is now called the Reichs ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Zona Glomerulosa
The ''zona glomerulosa'' (sometimes, glomerular zone) of the adrenal gland is the most superficial layer of the adrenal cortex, lying directly beneath the renal capsule. Its cells are ovoid and arranged in clusters or arches (''glomus'' is Latin for "ball"). In response to increased potassium levels, renin or decreased blood flow to the kidneys, cells of the ''zona glomerulosa'' produce and secrete the mineralocorticoid aldosterone into the blood as part of the renin–angiotensin system.Marieb Human Anatomy & Physiology 9th edition, chapter:16, page:629, question number:14 Although sustained production of aldosterone requires persistent calcium entry through low-voltage activated Ca2+ channels, isolated ''zona glomerulosa'' cells are considered nonexcitable, with recorded membrane voltages that are too hyperpolarized to permit Ca2+ channels entry. However, mouse ''zona glomerulosa'' cells within adrenal slices spontaneously generate membrane potential oscillations of low per ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Endocrinology
Endocrinology (from '' endocrine'' + '' -ology'') is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones. It is also concerned with the integration of developmental events proliferation, growth, and differentiation, and the psychological or behavioral activities of metabolism, growth and development, tissue function, sleep, digestion, respiration, excretion, mood, stress, lactation, movement, reproduction, and sensory perception caused by hormones. Specializations include behavioral endocrinology and comparative endocrinology. The endocrine system consists of several glands, all in different parts of the body, that secrete hormones directly into the blood rather than into a duct system. Therefore, endocrine glands are regarded as ductless glands. Hormones have many different functions and modes of action; one hormone may have several effects on different target organs, and, conversely, one target orga ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Biophysical
Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations. Biophysical research shares significant overlap with biochemistry, molecular biology, physical chemistry, physiology, nanotechnology, bioengineering, computational biology, biomechanics, developmental biology and systems biology. The term ''biophysics'' was originally introduced by Karl Pearson in 1892.Roland Glaser. Biophysics: An Introduction'. Springer; 23 April 2012. . The term ''biophysics'' is also regularly used in academia to indicate the study of the physical quantities (e.g. electric current, temperature, stress, entropy) in biological systems. Other biological sciences also perform research on the biophysical properties of living organisms including molecular biology, cell biology, chemical biology, and biochemistry. Overview Mol ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Florey Institute Of Neuroscience And Mental Health
The Florey Institute of Neuroscience and Mental Health, more commonly known as the Florey Institute, is an Australian medical research institute that undertakes clinical and applied research into treatments for brain and mind disorders and the cardiovascular system. The institute's areas of interest include Parkinson's disease, stroke, motor neurone disease, traumatic brain and spinal cord injury, addiction, epilepsy, multiple sclerosis, brain development in premature babies, Autism, Huntington's disease, depression, schizophrenia, brain function in health and disease, heart failure, and dementia. Affiliated with the University of Melbourne and the Austin Hospital, the institute is located in the Melbourne suburbs of and in Victoria. It is the largest brain research group in the southern hemisphere and employs approximately 600 staff and students. The institute is led by its director, Professor Steven Petrou, who specialises in the underlying electrophysiological basis of ge ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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University Of Melbourne
The University of Melbourne is a public research university located in Melbourne, Australia. Founded in 1853, it is Australia's second oldest university and the oldest in Victoria. Its main campus is located in Parkville, an inner suburb north of Melbourne's central business district, with several other campuses located across Victoria. Incorporated in the 19th century by the colony of Victoria, the University of Melbourne is one of Australia's six sandstone universities and a member of the Group of Eight, Universitas 21, Washington University's McDonnell International Scholars Academy, and the Association of Pacific Rim Universities. Since 1872, many residential colleges have become affiliated with the university, providing accommodation for students and faculty, and academic, sporting and cultural programs. There are ten colleges located on the main campus and in nearby suburbs. The university comprises ten separate academic units and is associated with numerous institut ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Physiology
Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical and physical functions in a living system. According to the classes of organisms, the field can be divided into medical physiology, animal physiology, plant physiology, cell physiology, and comparative physiology. Central to physiological functioning are biophysical and biochemical processes, homeostatic control mechanisms, and communication between cells. ''Physiological state'' is the condition of normal function. In contrast, ''pathological state'' refers to abnormal conditions, including human diseases. The Nobel Prize in Physiology or Medicine is awarded by the Royal Swedish Academy of Sciences for exceptional scientific achievements in physiology related to the field of medicine. Foundations Cells Although there are differ ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Urine
Urine is a liquid by-product of metabolism in humans and in many other animals. Urine flows from the kidneys through the ureters to the urinary bladder. Urination results in urine being excretion, excreted from the body through the urethra. Cell (biology), Cellular metabolism generates many by-products that are rich in nitrogen and must be clearance (medicine), cleared from the Circulatory system, bloodstream, such as urea, uric acid, and creatinine. These by-products are expelled from the body during urination, which is the primary method for excreting water-soluble chemicals from the body. A urinalysis can detect nitrogenous wastes of the mammalian body. Urine plays an important role in the earth's nitrogen cycle. In balanced ecosystems, urine fertilizes the soil and thus helps plants to grow. Therefore, Reuse of excreta, urine can be used as a fertilizer. Some animals use it to territory (animal)#Scent marking, mark their territories. Historically, aged or fermented urine (kn ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Nuclear Pharmacy
Nuclear pharmacy, also known as radiopharmacy, involves preparation of radioactive materials for patient administration that will be used to diagnose and treat specific diseases in nuclear medicine. It generally involves the practice of combining a radionuclide tracer with a pharmaceutical component that determines the biological localization in the patient. Radiopharmaceuticals are generally not designed to have a therapeutic effect themselves, but there is a risk to staff from radiation exposure and to patients from possible contamination in production. Due to these intersecting risks, nuclear pharmacy is a heavily regulated field. The majority of diagnostic nuclear medicine investigations are performed using technetium-99m. History The concept of nuclear pharmacy was first described in 1960 by Captain William H. Briner while at the National Institutes of Health (NIH) in Bethesda, Maryland. Along with Mr. Briner, John E. Christian, who was a professor in the School of Pharmacy ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Gregory Pincus
Gregory Goodwin Pincus (April 9, 1903 – August 22, 1967) was an American biologist and researcher who co-invented the combined oral contraceptive pill. Early life Gregory Goodwin Pincus was born in Woodbine, New Jersey to Jewish parents, who were immigrants from the Russian Empire. His father was Joseph Pincus, a teacher and the editor of a farm journal, and his mother was Elizabeth (née Lipman), whose family had come from the region that is now Latvia. He credited two uncles, both agricultural scientists, for his interest in research. His IQ was said to be 210 and his family considered him a genius. Pincus attended Cornell University and received a bachelor's degree in biology in 1924. He attended Harvard University, where he was an instructor in zoology while also working toward his master's and doctorate degrees. From 1927 to 1930 he moved from Harvard to Cambridge University in England to the Kaiser Wilhelm Institute for Biology with Richard Goldschmidt in Berlin where he ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Shrewsbury, Massachusetts
Shrewsbury (/ˈʃruzberi/ ''SHROOZ-bury'') is a town in Worcester County, Massachusetts, United States. Shrewsbury, unlike the surrounding towns of Grafton, Millbury, Westborough, Northborough, Boylston, and West Boylston did not become a mill town or farming village; most of its 19th-century growth was due to its proximity to Worcester and visitors to Lake Quinsigamond. The population was 38,325 according to the 2020 United States Census, in nearly 15,000 households. Incorporated in 1727, the town is governed now under the New England representative town meeting system, headed by the Town Manager and five-member elected Board of Selectmen whose duties include licensing, appointing various administrative positions, and calling a town meeting of citizens annually or whenever the need arises. History The Town of Shrewsbury, named for Shrewsbury, England, is a suburban community with an uneven and hilly terrain cut by a number of minor streams providing several small water ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |