Tadeusz Reichstein (20 July 1897 – 1 August 1996) was a
Polish
Polish may refer to:
* Anything from or related to Poland, a country in Europe
* Polish language
* Poles, people from Poland or of Polish descent
* Polish chicken
*Polish brothers (Mark Polish and Michael Polish, born 1970), American twin screenwr ...
-
Swiss
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* the adjectival form of Switzerland
* Swiss people
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*Swiss, North Carolina
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* Swiss-system tournament, in various games and sports
*Swiss Internati ...
chemist
A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties. Chemists carefully describe ...
and the
Nobel Prize in Physiology or Medicine
The Nobel Prize in Physiology or Medicine ( sv, Nobelpriset i fysiologi eller medicin) is awarded yearly by the Nobel Assembly at the Karolinska Institute, Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or ...
laureate (1950), which was awarded for his work on the isolation of
cortisone
Cortisone is a pregnene (21-carbon) steroid hormone. It is a naturally-occurring corticosteroid metabolite that is also used as a pharmaceutical prodrug; it is not synthesized in the adrenal glands. Cortisol is converted by the action of the ...
.
Early life
Reichstein was born into a
Polish-Jewish
The history of the Jews in Poland dates back at least 1,000 years. For centuries, Poland was home to the largest and most significant Ashkenazi Jewish community in the world. Poland was a principal center of Jewish culture, because of the lon ...
family at
Włocławek
Włocławek (Polish pronunciation: ; german: Leslau) is a city located in central Poland along the Vistula (Wisła) River and is bordered by the Gostynin-Włocławek Landscape Park. As of December 2021, the population of the city is 106,928. Loc ...
,
Russian Empire
The Russian Empire was an empire and the final period of the List of Russian monarchs, Russian monarchy from 1721 to 1917, ruling across large parts of Eurasia. It succeeded the Tsardom of Russia following the Treaty of Nystad, which ended th ...
. His parents were Gastawa (Brockmann) and Izydor Reichstein.
He spent his early childhood at
Kiev
Kyiv, also spelled Kiev, is the capital and most populous city of Ukraine. It is in north-central Ukraine along the Dnieper River. As of 1 January 2021, its population was 2,962,180, making Kyiv the seventh-most populous city in Europe.
Ky ...
, where his father was an engineer. He began his education at boarding-school in
Jena
Jena () is a German city and the second largest city in Thuringia. Together with the nearby cities of Erfurt and Weimar, it forms the central metropolitan area of Thuringia with approximately 500,000 inhabitants, while the city itself has a po ...
,
Germany
Germany, officially the Federal Republic of Germany (FRG),, is a country in Central Europe. It is the most populous member state of the European Union. Germany lies between the Baltic and North Sea to the north and the Alps to the sou ...
and arrived in
Basel
, french: link=no, Bâlois(e), it, Basilese
, neighboring_municipalities= Allschwil (BL), Hégenheim (FR-68), Binningen (BL), Birsfelden (BL), Bottmingen (BL), Huningue (FR-68), Münchenstein (BL), Muttenz (BL), Reinach (BL), Riehen (BS) ...
,
Switzerland at the age of 8.
Career
Reichstein studied under
Hermann Staudinger
Hermann Staudinger (; 23 March 1881 – 8 September 1965) was a German organic chemist who demonstrated the existence of macromolecules, which he characterized as polymers. For this work he received the 1953 Nobel Prize in Chemistry.
He is also ...
during the latter's brief stint at the
Technical University of Karlsruhe
The Karlsruhe Institute of Technology (KIT; german: Karlsruher Institut für Technologie) is a public university, public research university in Karlsruhe, Germany. The institute is a national research center of the Helmholtz Association.
KIT wa ...
. It was here that he met
Leopold Ruzicka
Leopold may refer to:
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* Leopold (given name)
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* Leopold (''The Simpsons''), Superintendent Chalmers' assistant on ''The Simpsons''
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, also a doctoral student.
[
In 1933, working in ]Zürich
, neighboring_municipalities = Adliswil, Dübendorf, Fällanden, Kilchberg, Maur, Oberengstringen, Opfikon, Regensdorf, Rümlang, Schlieren, Stallikon, Uitikon, Urdorf, Wallisellen, Zollikon
, twintowns = Kunming, San Francisco
Zürich () i ...
, Switzerland, at the ETHZ
(colloquially)
, former_name = eidgenössische polytechnische Schule
, image = ETHZ.JPG
, image_size =
, established =
, type = Public
, budget = CHF 1.896 billion (2021)
, rector = Günther Dissertori
, president = Joël Mesot
, ac ...
chemical laboratories of Ruzicka, Reichstein succeeded, independently of Sir Norman Haworth and his collaborators in the United Kingdom, in synthesizing vitamin C
Vitamin C (also known as ascorbic acid and ascorbate) is a water-soluble vitamin found in citrus and other fruits and vegetables, also sold as a dietary supplement and as a topical 'serum' ingredient to treat melasma (dark pigment spots) a ...
(ascorbic acid) in what is now called the Reichstein process. In 1937, he was appointed Associate Professor at ETHZ.[
In 1937, Reichstein moved to the University of Basle where he became Professor of Pharmaceutical Chemistry, and then, from 1946 until his retirement in 1967, of Organic Chemistry.][
Together with ]Edward Calvin Kendall
Edward Calvin Kendall (March 8, 1886 – May 4, 1972) was an American chemist. In 1950, Kendall was awarded the Nobel Prize for Physiology or Medicine along with Swiss chemist Tadeusz Reichstein and Mayo Clinic physician Philip S. Hench, for the ...
and Philip Showalter Hench, he was awarded the Nobel Prize in Physiology or Medicine
The Nobel Prize in Physiology or Medicine ( sv, Nobelpriset i fysiologi eller medicin) is awarded yearly by the Nobel Assembly at the Karolinska Institute, Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or ...
in 1950 for their work on hormones
A hormone (from the Greek participle , "setting in motion") is a class of signaling molecules in multicellular organisms that are sent to distant organs by complex biological processes to regulate physiology and behavior. Hormones are required fo ...
of the adrenal cortex
The adrenal cortex is the outer region and also the largest part of an adrenal gland. It is divided into three separate zones: zona glomerulosa, zona fasciculata and zona reticularis. Each zone is responsible for producing specific hormones. It ...
which culminated in the isolation of cortisone
Cortisone is a pregnene (21-carbon) steroid hormone. It is a naturally-occurring corticosteroid metabolite that is also used as a pharmaceutical prodrug; it is not synthesized in the adrenal glands. Cortisol is converted by the action of the ...
. In 1951, he and Kendall were jointly awarded the Cameron Prize for Therapeutics of the University of Edinburgh
The Cameron Prize for Therapeutics of the University of Edinburgh is awarded by the College of Medicine and Veterinary Medicine to a person who has made any highly important and valuable addition to Practical Therapeutics in the previous five ye ...
.
In later years, Reichstein became interested in the phytochemistry and cytology
Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living a ...
of ferns, publishing at least 80 papers on these subjects in the last three decades of his life. He had a particular interest in the use of chromosome
A chromosome is a long DNA molecule with part or all of the genetic material of an organism. In most chromosomes the very long thin DNA fibers are coated with packaging proteins; in eukaryotic cells the most important of these proteins ar ...
number and behavior in the interpretation of histories of hybridization and polyploidy
Polyploidy is a condition in which the cells of an organism have more than one pair of (homologous) chromosomes. Most species whose cells have nuclei (eukaryotes) are diploid, meaning they have two sets of chromosomes, where each set contains ...
, but also continued his earlier interest in the chemical constituents of the plants.
Retirement and death
Reichstein died at the age of 99 in Basel
, french: link=no, Bâlois(e), it, Basilese
, neighboring_municipalities= Allschwil (BL), Hégenheim (FR-68), Binningen (BL), Birsfelden (BL), Bottmingen (BL), Huningue (FR-68), Münchenstein (BL), Muttenz (BL), Reinach (BL), Riehen (BS) ...
, Switzerland. The principal industrial process for the artificial synthesis of vitamin C still bears his name. Reichstein was the longest-lived Nobel laureate at the time of his death, but was surpassed in 2008 by Rita Levi-Montalcini
Rita Levi-Montalcini (, ; 22 April 1909 – 30 December 2012) was an Italian Nobel laureate, honored for her work in neurobiology. She was awarded the 1986 Nobel Prize in Physiology or Medicine jointly with colleague Stanley Cohen for th ...
.
See also
* List of Jewish Nobel laureates
Nobel Prizes have been awarded to over 900 individuals, of whom at least 20% were Jews.
*
*
*
*
*
*
*
*
The number of Jews receiving Nobel prizes has been the subject of some attention.*
*
*"Jews rank high among winners of Nobel, but why ...
* List of Polish Nobel laureates
References
External links
* including the Nobel Lecture, December 11, 1950 ''Chemistry of the Adrenal Cortex Hormones''
Tadeus Reichstein article by B. Weintraub
{{DEFAULTSORT:Reichstein, Tadeusz
1897 births
1996 deaths
Nobel laureates in Physiology or Medicine
ETH Zurich faculty
Jewish Nobel laureates
Polish Nobel laureates
Swiss Nobel laureates
People from Włocławek
People from Warsaw Governorate
Jews from the Russian Empire
Swiss people of Polish-Jewish descent
Pteridologists
Polish chemists
Jewish chemists
Jewish scientists
ETH Zurich alumni
Foreign Members of the Royal Society
Foreign associates of the National Academy of Sciences
Recipients of the Copley Medal