Tadeusz Reichstein (20 July 1897 – 1 August 1996) was a

Polish Polish may refer to: * Anything from or related to Poland, a country in Europe * Polish language * Poles Poles,, ; singular masculine: ''Polak'', singular feminine: ''Polka'' or Polish people, are a West Slavic nation and ethnic group, w ...

Swiss Swiss may refer to: * the adjectival form of Switzerland * Swiss people Places * Swiss, Missouri * Swiss, North Carolina *Swiss, West Virginia * Swiss, Wisconsin Other uses *Swiss-system tournament, in various games and sports *Swiss Internation ...

chemist A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties. Chemists carefully describe th ...

and the

Nobel Prize in Physiology or Medicine The Nobel Prize in Physiology or Medicine is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, accord ...

laureate (1950), which was awarded for his work on the isolation of

cortisone Cortisone is a pregnene (21-carbon) steroid hormone. It is a naturally-occurring corticosteroid metabolite that is also used as a pharmaceutical prodrug; it is not synthesized in the adrenal glands. Cortisol is converted by the action of the enzy ...

Early life

Reichstein was born into a

Polish-Jewish The history of the Jews in Poland dates back at least 1,000 years. For centuries, Poland was home to the largest and most significant Ashkenazi Jewish community in the world. Poland was a principal center of Jewish culture, because of the lon ...

family at

Włocławek Włocławek (Polish pronunciation: ; german: Leslau) is a city located in central Poland along the Vistula (Wisła) River and is bordered by the Gostynin-Włocławek Landscape Park. As of December 2021, the population of the city is 106,928. Loc ...

Russian Empire The Russian Empire was an empire and the final period of the Russian monarchy from 1721 to 1917, ruling across large parts of Eurasia. It succeeded the Tsardom of Russia following the Treaty of Nystad, which ended the Great Northern War. ...

. His parents were Gastawa (Brockmann) and Izydor Reichstein. He spent his early childhood at

Kiev Kyiv, also spelled Kiev, is the capital and most populous city of Ukraine. It is in north-central Ukraine along the Dnieper, Dnieper River. As of 1 January 2021, its population was 2,962,180, making Kyiv the List of European cities by populat ...

, where his father was an engineer. He began his education at boarding-school in

Jena Jena () is a German city and the second largest city in Thuringia. Together with the nearby cities of Erfurt and Weimar, it forms the central metropolitan area of Thuringia with approximately 500,000 inhabitants, while the city itself has a popu ...

Germany Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated betwe ...

and arrived in

Basel , french: link=no, Bâlois(e), it, Basilese , neighboring_municipalities= Allschwil (BL), Hégenheim (FR-68), Binningen (BL), Birsfelden (BL), Bottmingen (BL), Huningue (FR-68), Münchenstein (BL), Muttenz (BL), Reinach (BL), Riehen (BS ...

Switzerland ). Swiss law does not designate a ''capital'' as such, but the federal parliament and government are installed in Bern, while other federal institutions, such as the federal courts, are in other cities (Bellinzona, Lausanne, Luzern, Neuchâtel ...

at the age of 8.

Career

Reichstein studied under

Hermann Staudinger Hermann Staudinger (; 23 March 1881 – 8 September 1965) was a German organic chemist who demonstrated the existence of macromolecules, which he characterized as polymers. For this work he received the 1953 Nobel Prize in Chemistry. He is also ...

during the latter's brief stint at the

Technical University of Karlsruhe The Karlsruhe Institute of Technology (KIT; german: Karlsruher Institut für Technologie) is a public research university in Karlsruhe, Germany. The institute is a national research center of the Helmholtz Association. KIT was created in 2009 w ...

. It was here that he met

Leopold Ruzicka Leopold may refer to: People * Leopold (given name) * Leopold (surname) Arts, entertainment, and media Fictional characters * Leopold (''The Simpsons''), Superintendent Chalmers' assistant on ''The Simpsons'' * Leopold Bloom, the protagonist o ...

, also a doctoral student. In 1933, working in

Zürich Zürich () is the list of cities in Switzerland, largest city in Switzerland and the capital of the canton of Zürich. It is located in north-central Switzerland, at the northwestern tip of Lake Zürich. As of January 2020, the municipality has 43 ...

, Switzerland, at the

ETHZ (colloquially) , former_name = eidgenössische polytechnische Schule , image = ETHZ.JPG , image_size = , established = , type = Public , budget = CHF 1.896 billion (2021) , rector = Günther Dissertori , president = Joël Mesot , a ...

chemical laboratories of Ruzicka, Reichstein succeeded, independently of Sir

Norman Haworth Sir Walter Norman Haworth FRS (19 March 1883 – 19 March 1950) was a British chemist best known for his groundbreaking work on ascorbic acid ( vitamin C) while working at the University of Birmingham. He received the 1937 Nobel Prize in Chem ...

and his collaborators in the United Kingdom, in synthesizing

vitamin C Vitamin C (also known as ascorbic acid and ascorbate) is a water-soluble vitamin found in citrus and other fruits and vegetables, also sold as a dietary supplement and as a topical 'serum' ingredient to treat melasma (dark pigment spots) an ...

(ascorbic acid) in what is now called the

Reichstein process The Reichstein process in chemistry is a combined chemical and microbial method for the production of ascorbic acid from D-glucose that takes place in several steps. This process was devised by Nobel Prize winner Tadeusz Reichstein and his colleagu ...

. In 1937, he was appointed Associate Professor at ETHZ. In 1937, Reichstein moved to the

University of Basle The University of Basel (Latin: ''Universitas Basiliensis'', German: ''Universität Basel'') is a university in Basel, Switzerland. Founded on 4 April 1460, it is Switzerland's oldest university and among the world's oldest surviving universitie ...

where he became Professor of Pharmaceutical Chemistry, and then, from 1946 until his retirement in 1967, of Organic Chemistry. Together with

Edward Calvin Kendall Edward Calvin Kendall (March 8, 1886 – May 4, 1972) was an American chemist. In 1950, Kendall was awarded the Nobel Prize for Physiology or Medicine along with Swiss chemist Tadeusz Reichstein and Mayo Clinic physician Philip S. Hench, for the ...

and

Philip Showalter Hench Philip Showalter Hench (February 28, 1896 – March 30, 1965) was an American physician. Hench, along with his Mayo Clinic co-worker Edward Calvin Kendall and Swiss chemist Tadeus Reichstein was awarded the Nobel Prize for Physiology or Medici ...

, he was awarded the

in 1950 for their work on

hormones A hormone (from the Ancient Greek, Greek participle , "setting in motion") is a class of cell signaling, signaling molecules in multicellular organisms that are sent to distant organs by complex biological processes to regulate physiology and beh ...

of the

adrenal cortex The adrenal cortex is the outer region and also the largest part of an adrenal gland. It is divided into three separate zones: zona glomerulosa, zona fasciculata and zona reticularis. Each zone is responsible for producing specific hormones. It is ...

which culminated in the isolation of

. In 1951, he and Kendall were jointly awarded the Cameron Prize for Therapeutics of the University of Edinburgh. In later years, Reichstein became interested in the phytochemistry and

cytology Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living and ...

of ferns, publishing at least 80 papers on these subjects in the last three decades of his life. He had a particular interest in the use of

chromosome A chromosome is a long DNA molecule with part or all of the genetic material of an organism. In most chromosomes the very long thin DNA fibers are coated with packaging proteins; in eukaryotic cells the most important of these proteins are ...

number and behavior in the interpretation of histories of hybridization and

polyploidy Polyploidy is a condition in which the cells of an organism have more than one pair of ( homologous) chromosomes. Most species whose cells have nuclei ( eukaryotes) are diploid, meaning they have two sets of chromosomes, where each set contain ...

, but also continued his earlier interest in the chemical constituents of the plants.

Retirement and death

Reichstein died at the age of 99 in

, Switzerland. The principal industrial process for the artificial synthesis of vitamin C still bears his name. Reichstein was the longest-lived Nobel laureate at the time of his death, but was surpassed in 2008 by

Rita Levi-Montalcini Rita Levi-Montalcini (, ; 22 April 1909 – 30 December 2012) was an Italian Nobel laureate, honored for her work in neurobiology. She was awarded the 1986 Nobel Prize in Physiology or Medicine jointly with colleague Stanley Cohen for the ...

References

External links

* including the Nobel Lecture, December 11, 1950 ''Chemistry of the Adrenal Cortex Hormones''
Tadeus Reichstein article by B. Weintraub
{{DEFAULTSORT:Reichstein, Tadeusz 1897 births 1996 deaths Nobel laureates in Physiology or Medicine ETH Zurich faculty Jewish Nobel laureates Polish Nobel laureates Swiss Nobel laureates People from Włocławek People from Warsaw Governorate Jews from the Russian Empire Swiss people of Polish-Jewish descent Pteridologists Polish chemists Jewish chemists Jewish scientists ETH Zurich alumni Foreign Members of the Royal Society Foreign associates of the National Academy of Sciences Recipients of the Copley Medal

Early life

Career

Retirement and death

See also

References

External links