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Tadeus Reichstein
Tadeusz Reichstein (20 July 1897 – 1 August 1996) was a Polish-Swiss chemist and the Nobel Prize in Physiology or Medicine laureate (1950), which was awarded for his work on the isolation of cortisone. Early life Reichstein was born into a Polish-Jewish family at Włocławek, Russian Empire. His parents were Gastawa (Brockmann) and Izydor Reichstein. He spent his early childhood at Kiev, where his father was an engineer. He began his education at boarding-school in Jena, Germany and arrived in Basel, Switzerland at the age of 8. Career Reichstein studied under Hermann Staudinger during the latter's brief stint at the Technical University of Karlsruhe. It was here that he met Leopold Ruzicka, also a doctoral student. In 1933, working in Zürich, Switzerland, at the ETHZ chemical laboratories of Ruzicka, Reichstein succeeded, independently of Sir Norman Haworth and his collaborators in the United Kingdom, in synthesizing vitamin C (ascorbic acid) in what is now called the Reichs ...
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Włocławek
Włocławek (Polish pronunciation: ; german: Leslau) is a city located in central Poland along the Vistula (Wisła) River and is bordered by the Gostynin-Włocławek Landscape Park. As of December 2021, the population of the city is 106,928. Located in the Kuyavian-Pomeranian Voivodeship, it was the capital of Włocławek Voivodeship until 1999. The city is located in the historical region of Kuyavia and is the region's third largest city after Bydgoszcz and Toruń. History Włocławek's history dates back to the late Bronze Age – early Iron Age (1300 BCE – 500 BCE). Archaeological excavations conducted on the current city site uncovered the remains of a settlement belonging to the Lusatian culture, as well as evidence of a settlement of early Pomeranian culture which had been established. Traces of additional settlements dating to the Roman period and the early Middle Ages have also been excavated in the area. Middle Ages Precise dating of the city's founding has proven ...
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Polish Jews
The history of the Jews in Poland dates back at least 1,000 years. For centuries, Poland was home to the largest and most significant Ashkenazi Jewish community in the world. Poland was a principal center of Jewish culture, because of the long period of statutory religious tolerance and social autonomy which ended after the Partitions of Poland in the 18th century. During World War II there was a nearly complete genocidal destruction of the Polish Jewish community by Nazi Germany and its collaborators of various nationalities, during the German occupation of Poland between 1939 and 1945, called the Holocaust. Since the fall of communism in Poland, there has been a renewed interest in Jewish culture, featuring an annual Jewish Culture Festival, new study programs at Polish secondary schools and universities, and the opening of Warsaw's Museum of the History of Polish Jews. From the founding of the Kingdom of Poland in 1025 until the early years of the Polish–Lithuanian Comm ...
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University Of Basle
The University of Basel (Latin: ''Universitas Basiliensis'', German: ''Universität Basel'') is a university in Basel, Switzerland. Founded on 4 April 1460, it is Switzerland's oldest university and among the world's oldest surviving universities. The university is traditionally counted among the leading institutions of higher learning in the country. The associated Basel University Library is the largest and among the most important libraries in Switzerland. The university hosts the faculties of theology, law, medicine, humanities and social sciences, science, psychology, and business and economics, as well as numerous cross-disciplinary subjects and institutes, such as the Biozentrum for biomedical research and the Institute for European Global Studies. In 2020, the university had 13,139 students and 378 professors. International students accounted for 27 percent of the student body. In its over 500-year history, the university has been home to Erasmus of Rotterdam, Paracelsu ...
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Biogr
''Biography: An Interdisciplinary Quarterly'' is an international, academic journal that provides a forum for biographical scholarship. Its articles explore the theoretical, generic, historical, and cultural dimensions of life-writing; and the integration of literature, history, the arts, and the social sciences as they relate to biography. It also offers reviews, concise excerpts of reviews published elsewhere, an annual bibliography of works about biography, and listings of upcoming events, calls for papers, and news from the field. The journal was founded in 1978 by George Simson, a professor of literature at the University of Hawaii. Simson also founded the nonprofit Biographical Research Center (BRC) and the University's Center for Biographical Research (CBR). The journal is owned by the BRC and published by the University of Hawaii Press. For several years Professor Donald James Winslow of the University of Boston was the magazine's bibliographer. In 1994, the editorship passe ...
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Reichstein Process
The Reichstein process in chemistry is a combined chemical and microbial method for the production of ascorbic acid from D-glucose that takes place in several steps. This process was devised by Nobel Prize winner Tadeusz Reichstein and his colleagues in 1933 while working in the laboratory of the ETH in Zürich. Reaction steps The reaction steps are: * hydrogenation of D-glucose to D-sorbitol, an organic reaction with nickel as a catalyst under high temperature and high pressure. * Microbial oxidation or fermentation of sorbitol to L-sorbose with acetobacter at pH 4-6 and 30 °C. * protection of the 4 hydroxyl groups in sorbose by formation of the acetal with acetone and an acid to Diacetone-L-sorbose (2,3:4,6−Diisopropyliden−α−L−sorbose) * Organic oxidation with potassium permanganate (to Diprogulic acid) followed by heating with water gives the 2-Keto-L-gulonic acid * The final step is a ring-closing step or gamma lactonization with removal of water. * Intermedia ...
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Vitamin C
Vitamin C (also known as ascorbic acid and ascorbate) is a water-soluble vitamin found in citrus and other fruits and vegetables, also sold as a dietary supplement and as a topical 'serum' ingredient to treat melasma (dark pigment spots) and wrinkles on the face. It is used to prevent and treat scurvy. Vitamin C is an essential nutrient involved in the repair of tissue, the formation of collagen, and the enzymatic production of certain neurotransmitters. It is required for the functioning of several enzymes and is important for immune system function. It also functions as an antioxidant. Most animals are able to synthesize their own vitamin C. However, apes (including humans) and monkeys (but not all primates), most bats, some rodents, and certain other animals must acquire it from dietary sources. There is some evidence that regular use of supplements may reduce the duration of the common cold, but it does not appear to prevent infection. It is unclear whether supple ...
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Norman Haworth
Sir Walter Norman Haworth FRS (19 March 1883 – 19 March 1950) was a British chemist best known for his groundbreaking work on ascorbic acid (vitamin C) while working at the University of Birmingham. He received the 1937 Nobel Prize in Chemistry "for his investigations on carbohydrates and vitamin C". The prize was shared with Swiss chemist Paul Karrer for his work on other vitamins. Haworth worked out the correct structure of a number of sugars, and is known among organic chemists for his development of the Haworth projection that translates three-dimensional sugar structures into convenient two-dimensional graphical form. Academic career Having worked for some time from the age of fourteen in the local Ryland's linoleum factory managed by his father, he studied for and successfully passed the entrance examination to the University of Manchester in 1903 to study chemistry. He made this pursuit in spite of active discouragement by his parents. He gained his first-class hono ...
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ETHZ
(colloquially) , former_name = eidgenössische polytechnische Schule , image = ETHZ.JPG , image_size = , established = , type = Public , budget = CHF 1.896 billion (2021) , rector = Günther Dissertori , president = Joël Mesot , academic_staff = 6,612 (including doctoral students, excluding 527 professors of all ranks, 34% female, 65% foreign nationals) (full-time equivalents 2021) , administrative_staff = 3,106 (40% female, 19% foreign nationals, full-time equivalents 2021) , students = 24,534 (headcount 2021, 33.3% female, 37% foreign nationals) , undergrad = 10,642 , postgrad = 8,299 , doctoral = 4,460 , other = 1,133 , address = Rämistrasse 101CH-8092 ZürichSwitzerland , city = Zürich , coor = , campus = Urban , language = German, English (Masters and upwards, sometimes Bachelor) , affiliations = CESAER, EUA, GlobalTech, IARU, IDEA League, UNITECH , website ethz.ch, colors = Black and White , logo = ETH Zürich Logo black.svg ETH Züric ...
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Zürich
Zürich () is the list of cities in Switzerland, largest city in Switzerland and the capital of the canton of Zürich. It is located in north-central Switzerland, at the northwestern tip of Lake Zürich. As of January 2020, the municipality has 434,335 inhabitants, the Urban agglomeration, urban area 1.315 million (2009), and the Zürich metropolitan area 1.83 million (2011). Zürich is a hub for railways, roads, and air traffic. Both Zurich Airport and Zürich Hauptbahnhof, Zürich's main railway station are the largest and busiest in the country. Permanently settled for over 2,000 years, Zürich was founded by the Roman Empire, Romans, who called it '. However, early settlements have been found dating back more than 6,400 years (although this only indicates human presence in the area and not the presence of a town that early). During the Middle Ages, Zürich gained the independent and privileged status of imperial immediacy and, in 1519, became a primary centre of the Protestant ...
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Leopold Ruzicka
Leopold may refer to: People * Leopold (given name) * Leopold (surname) Arts, entertainment, and media Fictional characters * Leopold (''The Simpsons''), Superintendent Chalmers' assistant on ''The Simpsons'' * Leopold Bloom, the protagonist of James Joyce's ''Ulysses'' * Leopold "Leo" Fitz, a character on the television series ''Agents of S.H.I.E.L.D.'' * Leopold "Butters" Stotch, a character on the television series ''South Park'' * General Leopold von Flockenstuffen, a character in the BBC sitcom Allo 'Allo!'' * Leopold the Cat, Russian cartoon character Other arts, entertainment, and media * Leopold (prize), a biennial German prize for music for children * ''Kate & Leopold'', 2001 romantic comedy film * ''King Leopold's Ghost'', popular history book by Adam Hochschild * "King Leopold's Soliloquy", 1905 pamphlet by Mark Twain. * ''Leopold the Cat'', television series * Léopold Nord & Vous, Belgian musical band Brands and enterprises *Leopold (publisher), a Netherlands-b ...
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Technical University Of Karlsruhe
The Karlsruhe Institute of Technology (KIT; german: Karlsruher Institut für Technologie) is a public research university in Karlsruhe, Germany. The institute is a national research center of the Helmholtz Association. KIT was created in 2009 when the University of Karlsruhe (), founded in 1825 as a public research university and also known as the "Fridericiana", merged with the Karlsruhe Research Center (), which had originally been established in 1956 as a national nuclear research center (, or KfK). KIT is a member of the TU9, an incorporated society of the largest and most notable German institutes of technology.TU9 As part of the German Universities Excellence Initiative KIT was one of three universities which were awarded excellence status in 2006. In the following "German Excellence Strategy" KIT was awarded as one of eleven "Excellence Universities" in 2019. KIT is among the leading technical universities in Germany and Europe. According to different bibliometric rankin ...
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Hermann Staudinger
Hermann Staudinger (; 23 March 1881 – 8 September 1965) was a German organic chemist who demonstrated the existence of macromolecules, which he characterized as polymers. For this work he received the 1953 Nobel Prize in Chemistry. He is also known for his discovery of ketenes and of the Staudinger reaction. Staudinger, together with Leopold Ružička, also elucidated the molecular structures of pyrethrin I and II in the 1920s, enabling the development of pyrethroid insecticides in the 1960s and 1970s. Early work Staudinger was born in 1881 in Worms. Staudinger, who initially wanted to become a botanist, studied chemistry at the University of Halle, at the TH Darmstadt and at the LMU Munich. He received his "Verbandsexamen" (comparable to Master's degree) from TH Darmstadt. After receiving his Ph.D. from the University of Halle in 1903, Staudinger qualified as an academic lecturer at the University of Strasbourg in 1907. It was here that he discovered the ketenes, a family ...
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