Edward Calvin Kendall
Edward Calvin Kendall (March 8, 1886 – May 4, 1972) was an American chemist. In 1950, Kendall was awarded the Nobel Prize for Physiology or Medicine along with Swiss chemist Tadeusz Reichstein and Mayo Clinic physician Philip S. Hench, for their work with the hormones of the adrenal gland. Kendall did not only focus on the adrenal glands, he was also responsible for the isolation of thyroxine, a hormone of the thyroid gland and worked with the team that crystallized glutathione and identified its chemical structure. Kendall was a biochemist at the Graduate School of the Mayo Foundation at the time of the award. He received his education at Columbia University. After retiring from his job with the Mayo Foundation, Kendall joined the faculty at Princeton University, where he remained until his death in 1972. Kendall Elementary School, in Norwalk is named for him. Early life and education Kendall was born in South Norwalk, Connecticut in 1886. He attended Columbia University ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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South Norwalk
South Norwalk is a neighborhood in Norwalk, Connecticut which corresponds to the city's Second Taxing District. Often referred to as SoNo, the neighborhood was originally settled as Old Well, then chartered as the city of South Norwalk on August 18, 1870. The cities of Norwalk and South Norwalk were incorporated on June 6, 1913. South Norwalk underwent major redevelopment during the early 21st century, with many new apartments being constructed, often in close proximity to South Norwalk station, and generally more expensive than existing housing. South Norwalk is a diverse neighborhood both from a socioeconomic and racial perspective. The neighborhood hosts the annual SoNo Arts Festival, an event that showcases local artists, businesses, and musical acts. The annual Norwalk Oyster Festival, sponsored by the Norwalk Seaport Association, is held at Veteran's Memorial Park, across the Norwalk Harbor in East Norwalk. History Old Well The area of present-day South Norwalk develop ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tadeusz Reichstein
Tadeusz Reichstein (20 July 1897 – 1 August 1996) was a Polish-Swiss chemist and the Nobel Prize in Physiology or Medicine laureate (1950), which was awarded for his work on the isolation of cortisone. Early life Reichstein was born into a Polish-Jewish family at Włocławek, Russian Empire. His parents were Gastawa (Brockmann) and Izydor Reichstein. He spent his early childhood at Kiev, where his father was an engineer. He began his education at boarding-school in Jena, Germany and arrived in Basel, Switzerland at the age of 8. Career Reichstein studied under Hermann Staudinger during the latter's brief stint at the Technical University of Karlsruhe. It was here that he met Leopold Ruzicka, also a doctoral student. In 1933, working in Zürich, Switzerland, at the ETHZ chemical laboratories of Ruzicka, Reichstein succeeded, independently of Sir Norman Haworth and his collaborators in the United Kingdom, in synthesizing vitamin C (ascorbic acid) in what is now called the Reichs ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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University Of Cincinnati
The University of Cincinnati (UC or Cincinnati) is a public research university in Cincinnati, Ohio. Founded in 1819 as Cincinnati College, it is the oldest institution of higher education in Cincinnati and has an annual enrollment of over 44,000 students, making it the second largest university in Ohio. It is part of the University System of Ohio. The university has four major campuses, with Cincinnati's main uptown campus and medical campus in the Heights and Corryville neighborhoods, and branch campuses in Batavia and Blue Ash, Ohio. The university has 14 constituent colleges, with programs in architecture, business, education, engineering, humanities, the sciences, law, music, and medicine. The medical college includes a leading teaching hospital and several biomedical research laboratories, with developments made including a live polio vaccine and diphenhydramine. UC was also the first university to implement a co-operative education (co-op) model. The university is accre ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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American Academy Of Achievement
The American Academy of Achievement, colloquially known as the Academy of Achievement, is a non-profit educational organization that recognizes some of the highest achieving individuals in diverse fields and gives them the opportunity to meet one another. The academy also brings together the leaders with promising graduate students for mentorship. The academy hosts an International Achievement Summit, which ends with an awards ceremony, during which new members are inducted into the academy. History Founded in 1961 by ''Sports Illustrated'' and ''LIFE'' magazine photographer Brian Reynolds, the Academy of Achievement recognizes the highest achievers in public service, business, science and exploration, sports and the arts. Reynolds established the academy after he realized that the famous people he photographed from different fields did not usually have the opportunity to interact with one another. The organization was described in a 1989 ''San Francisco Chronicle'' artic ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Academy Of Achievement
The American Academy of Achievement, colloquially known as the Academy of Achievement, is a non-profit educational organization that recognizes some of the highest achieving individuals in diverse fields and gives them the opportunity to meet one another. The academy also brings together the leaders with promising graduate students for mentorship. The academy hosts an International Achievement Summit, which ends with an awards ceremony, during which new members are inducted into the academy. History Founded in 1961 by ''Sports Illustrated'' and ''LIFE'' magazine photographer Brian Reynolds, the Academy of Achievement recognizes the highest achievers in public service, business, science and exploration, sports and the arts. Reynolds established the academy after he realized that the famous people he photographed from different fields did not usually have the opportunity to interact with one another. The organization was described in a 1989 ''San Francisco Chronicle'' artic ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tadeus Reichstein
Tadeusz Reichstein (20 July 1897 – 1 August 1996) was a Polish-Swiss chemist and the Nobel Prize in Physiology or Medicine laureate (1950), which was awarded for his work on the isolation of cortisone. Early life Reichstein was born into a Polish-Jewish family at Włocławek, Russian Empire. His parents were Gastawa (Brockmann) and Izydor Reichstein. He spent his early childhood at Kiev, where his father was an engineer. He began his education at boarding-school in Jena, Germany and arrived in Basel, Switzerland at the age of 8. Career Reichstein studied under Hermann Staudinger during the latter's brief stint at the Technical University of Karlsruhe. It was here that he met Leopold Ruzicka, also a doctoral student. In 1933, working in Zürich, Switzerland, at the ETHZ chemical laboratories of Ruzicka, Reichstein succeeded, independently of Sir Norman Haworth and his collaborators in the United Kingdom, in synthesizing vitamin C (ascorbic acid) in what is now called the Reichs ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen following rest. Most commonly, the wrist and hands are involved, with the same joints typically involved on both sides of the body. The disease may also affect other parts of the body, including skin, eyes, lungs, heart, nerves and blood. This may result in a low red blood cell count, inflammation around the lungs, and inflammation around the heart. Fever and low energy may also be present. Often, symptoms come on gradually over weeks to months. While the cause of rheumatoid arthritis is not clear, it is believed to involve a combination of genetic and environmental factors. The underlying mechanism involves the body's immune system attacking the joints. This results in inflammation and thickening of the joint capsule. It also affects the underlying bone and cartilage. The diagnosis is made mos ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Adrenal Gland
The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. They are found above the kidneys. Each gland has an outer cortex which produces steroid hormones and an inner medulla. The adrenal cortex itself is divided into three main zones: the zona glomerulosa, the zona fasciculata and the zona reticularis. The adrenal cortex produces three main types of steroid hormones: mineralocorticoids, glucocorticoids, and androgens. Mineralocorticoids (such as aldosterone) produced in the zona glomerulosa help in the regulation of blood pressure and electrolyte balance. The glucocorticoids cortisol and cortisone are synthesized in the zona fasciculata; their functions include the regulation of metabolism and immune system suppression. The innermost layer of the cortex, the zona reticularis, produces androgens that are converted to fully functional sex hormones in the gonads ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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South Norwalk, Connecticut
South Norwalk is a neighborhood in Norwalk, Connecticut which corresponds to the city's Second Taxing District. Often referred to as SoNo, the neighborhood was originally settled as Old Well, then chartered as the city of South Norwalk on August 18, 1870. The cities of Norwalk and South Norwalk were incorporated on June 6, 1913. South Norwalk underwent major redevelopment during the early 21st century, with many new apartments being constructed, often in close proximity to South Norwalk station, and generally more expensive than existing housing. South Norwalk is a diverse neighborhood both from a socioeconomic and racial perspective. The neighborhood hosts the annual SoNo Arts Festival, an event that showcases local artists, businesses, and musical acts. The annual Norwalk Oyster Festival, sponsored by the Norwalk Seaport Association, is held at Veteran's Memorial Park, across the Norwalk Harbor in East Norwalk. History Old Well The area of present-day South Norwalk develop ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Norwalk, Connecticut
, image_map = Fairfield County Connecticut incorporated and unincorporated areas Norwalk highlighted.svg , mapsize = 230px , map_caption = Location in Fairfield County, Connecticut, Fairfield County and Connecticut , coordinates = , pushpin_map = USA#Connecticut , pushpin_label_position = top , pushpin_label = Norwalk , pushpin_map_caption = Location in the United States and Connecticut , subdivision_type = Country , subdivision_name = , subdivision_type1 = U.S. state , subdivision_name1 = , subdivision_type2 = County (United States), County , subdivision_name2 = Fairfield County, Connecticut, Fairfield , subdivision_type3 = Councils of governments in Connecticut, Region , subdivision_name3 = Western Connecticut, Western CT , established_title = Settled , established_date = February 26, 1640 , established_title2 = Municipal corpor ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Mayo Foundation
The Mayo Clinic () is a nonprofit American academic medical center focused on integrated health care, education, and research. It employs over 4,500 physicians and scientists, along with another 58,400 administrative and allied health staff, across three major campuses: Rochester, Minnesota; Jacksonville, Florida; and Phoenix/Scottsdale, Arizona. The practice specializes in treating difficult cases through tertiary care and destination medicine. It is home to the top-15 ranked Mayo Clinic Alix School of Medicine in addition to many of the highest regarded residency education programs in the United States. It spends over $660 million a year on research and has more than 3,000 full-time research personnel. William Worrall Mayo settled his family in Rochester in 1864 and opened a sole proprietorship medical practice that evolved under his sons, Will and Charlie Mayo, along with practice partners Stinchfield, Graham, Plummer, Millet, Judd, and Balfour, into Mayo Clinic. T ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Glutathione
Glutathione (GSH, ) is an antioxidant in plants, animals, fungi, and some bacteria and archaea. Glutathione is capable of preventing damage to important cellular components caused by sources such as reactive oxygen species, free radicals, peroxides, lipid peroxides, and heavy metals. It is a tripeptide with a gamma peptide linkage between the carboxyl group of the glutamate side chain and cysteine. The carboxyl group of the cysteine residue is attached by normal peptide linkage to glycine. Biosynthesis and occurrence Glutathione biosynthesis involves two adenosine triphosphate-dependent steps: *First, γ-glutamylcysteine is synthesized from L- glutamate and cysteine. This conversion requires the enzyme glutamate–cysteine ligase (GCL, glutamate cysteine synthase). This reaction is the rate-limiting step in glutathione synthesis. *Second, glycine is added to the C-terminal of γ-glutamylcysteine. This condensation is catalyzed by glutathione synthetase. While all animal ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |