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Hoppe-Seyler
Ernst Felix Immanuel Hoppe-Seyler (''né'' Felix Hoppe; 26 December 1825 – 10 August 1895) was a German physiologist and chemist, and the principal founder of the disciplines of biochemistry and molecular biology. Biography Hoppe-Seyler was born in Freyburg an der Unstrut in the Province of Saxony. He originally trained to be a physician in Halle and Leipzig, and received his medical doctorate from Berlin in 1851. Afterwards, he was an assistant to Rudolf Virchow at the Pathological Institute in Berlin. Hoppe-Seyler preferred scientific research to medicine, and later held positions in anatomy, applied chemistry, and physiological chemistry in Greifswald, Tübingen and Strasbourg. At Strasbourg, he was head of the department of biochemistry, the only such institution in Germany at the time. His work also led to advances in organic chemistry by his students and by immunologist Paul Ehrlich. Among his students and collaborators were Friedrich Miescher (1844–1895) and Nobel l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Albrecht Kossel
Ludwig Karl Martin Leonhard Albrecht Kossel (; 16 September 1853 – 5 July 1927) was a German biochemist and pioneer in the study of genetics. He was awarded the Nobel Prize for Physiology or Medicine in 1910 for his work in determining the chemical composition of nucleic acids, the genetic substance of biological cells. Kossel isolated and described the five organic compounds that are present in nucleic acid: adenine, cytosine, guanine, thymine, and uracil. These compounds were later shown to be nucleobases, and are key in the formation of DNA and RNA, the genetic material found in all living cells. Kossel was an important influence on and collaborator with other important researchers in biochemistry, including Henry Drysdale Dakin, Friedrich Miescher, Edwin B. Hart, and his professor and mentor, Felix Hoppe-Seyler. Kossel was editor of the Zeitschrift für Physiologische Chemie (Journal of Physiological Chemistry) from 1895 until his death. Kossel also conducted important ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hans Thierfelder
Hans Thierfelder (22 February 1858 – 11 November 1930) was a German biochemist and professor at the University of Tübingen. He studied lipids and phospholipids and was involved in isolating cerebrone, the first glycolipid in 1900. Thierfelder was born in Rostock where his father Theodor, was a professor of medicine. He graduated from the Rostock Gymnasium and studied medicine from 1876 at Rostock, moving to Tübingen, Heidelberg, Munich and finally graduated in 1881 at Freiburg. Influenced in physiology by Carl von Voit and Wilhelm Kühne he began to work under Otto Nasse at the Institute for Pharmacology and Physiological Chemistry, Rostock. He received an MD in 1883. Preferring research to medical practice he went to work as an assistant to Felix Hoppe-Seyler at Strassburg, and habilitated in 1887. Here he worked with Joseph von Mering on tertiary alcohols and the production of glucuronic acid in urine. Thierfelder published most of his research in the journal begun by Hoppe-S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Friedrich Miescher
Johannes Friedrich Miescher (13 August 1844 – 26 August 1895) was a Swiss physician and biologist. He was the first scientist to isolate nucleic acid in 1869. He also identified protamine and made a number of other discoveries. Miescher had isolated various phosphate-rich chemicals, which he called ''nuclein'' (now nucleic acids), from the nuclei of white blood cells in Felix Hoppe-Seyler's laboratory at the University of Tübingen, Germany, paving the way for the identification of DNA as the carrier of inheritance. The significance of the discovery, first published in 1871, was not at first apparent, and Albrecht Kossel made the initial inquiries into its chemical structure. Later, Miescher raised the idea that the nucleic acids could be involved in heredity and even posited that there might be something akin to an alphabet that might explain how variation is produced. Early life and education Friedrich Miescher came from a scientific family; his father and his uncle held th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eugen Baumann
Eugen Baumann (12 December 1846 – 3 November 1896) was a German chemist. He was one of the first people to create polyvinyl chloride (PVC), and, together with Carl Schotten, he discovered the Schotten-Baumann reaction. Life Baumann was born in Cannstatt, which is now part of Stuttgart. After he attended a gymnasium in Stuttgart, he was educated in the pharmacy of his father. During his time in Stuttgart, he attended the lectures of Hermann von Fehling at the University of Stuttgart. To broaden his education, he went to Lübeck and Gothenburg to work in pharmacies there. Later, he studied pharmacy at the University of Tübingen. He passed his first exam in 1870 and received his PhD in 1872 for work with Felix Hoppe-Seyler. He followed Hoppe-Seyler to the University of Straßburg where did his habilitation in 1876. The same year, Emil Heinrich Du Bois-Reymond offered him a position as the Head of the Chemistry Department of the Institute of Physiology in Berlin. In 1882, Bauman ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biochemistry
Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all areas of the life sciences are being uncovered and developed through biochemical methodology and research. Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis which allows biological molecules to give rise to the processes that occur within living cells and between cells,Karp (2009), p. 2. in turn relating greatly to the understanding of tissues and organs, as well as organism structure and function.Miller (2012). p. 62. Biochemistry is closely related to molecular biology, which is the study of the molecular mechanisms of biological phenomena.As ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alexander Schmidt (physiologist)
Hermann Adolf Alexander Schmidt ( – ) was a Baltic German physiologist from what was then the Governorate of Livonia in the Russian Empire. He was born on the island of Moon, which is today known by its Estonian name Muhu, in present-day Estonia. In 1858, he received his medical doctorate from the University of Dorpat, and later was an assistant to Felix Hoppe-Seyler (1825-1895) in Berlin, and to Carl Ludwig (1816-1895) in Leipzig. In 1869 he succeeded Friedrich Bidder (1810-1894) as professor of physiology at Dorpat, where he remained for the rest of his life. From 1885 to 1889 he served as university rector. Schmidt is remembered for his research involving the process of blood coagulation by demonstrating that the transformation of fibrinogen into fibrin was the result of an enzymatic process. He named the hypothetical enzyme "thrombin", and he called its precursor "prothrombin". Schmidt is credited for providing a foundation for the creation of anti-coagulation systems ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Freyburg, Germany
Freyburg is a town in the Burgenlandkreis district, in Saxony-Anhalt, Germany. It is situated on the river Unstrut, 9 km northwest of Hanseatic Naumburg, 63 km from Leipzig and 231 km from Berlin. It is part of the ''Verwaltungsgemeinschaft'' ("collective municipality") Unstruttal. On 1 July 2009 it absorbed the former municipalities Pödelist, Schleberoda, Weischütz and Zeuchfeld. Freyburg consists of the ''Ortsteile'' (divisions) Dobichau, Freyburg, Nißmitz, Pödelist, Schleberoda, Weischütz, Zeuchfeld and Zscheiplitz.Hauptsatzung der Stadt Freyburg (Unstrut) July 2019. The town is a tourist destination, best known for its vineyards, historic town centre, superb 11th-century castle and associations with [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
German Empire
The German Empire (),Herbert Tuttle wrote in September 1881 that the term "Reich" does not literally connote an empire as has been commonly assumed by English-speaking people. The term literally denotes an empire – particularly a hereditary empire led by an emperor, although has been used in German to denote the Roman Empire because it had a weak hereditary tradition. In the case of the German Empire, the official name was , which is properly translated as "German Empire" because the official position of head of state in the constitution of the German Empire was officially a "presidency" of a confederation of German states led by the King of Prussia who would assume "the title of German Emperor" as referring to the German people, but was not emperor of Germany as in an emperor of a state. –The German Empire" ''Harper's New Monthly Magazine''. vol. 63, issue 376, pp. 591–603; here p. 593. also referred to as Imperial Germany, the Second Reich, as well as simply Germany, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
German Confederation
The German Confederation (german: Deutscher Bund, ) was an association of 39 predominantly German-speaking sovereign states in Central Europe. It was created by the Congress of Vienna in 1815 as a replacement of the former Holy Roman Empire, which had been dissolved in 1806. The Confederation had only one organ, the Federal Convention (also Federal Assembly or Confederate Diet). The Convention consisted of the representatives of the member states. The most important issues had to be decided on unanimously. The Convention was presided over by the representative of Austria. This was a formality, however, the Confederation did not have a head of state, since it was not a state. The Confederation, on the one hand, was a strong alliance between its member states because federal law was superior to state law (the decisions of the Federal Convention were binding for the member states). Additionally, the Confederation had been established for eternity and was impossible to dissolve (l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Biology
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physical structure of biological macromolecules is known as molecular biology. Molecular biology was first described as an approach focused on the underpinnings of biological phenomena - uncovering the structures of biological molecules as well as their interactions, and how these interactions explain observations of classical biology. In 1945 the term molecular biology was used by physicist William Astbury. In 1953 Francis Crick, James Watson, Rosalind Franklin, and colleagues, working at Medical Research Council unit, Cavendish laboratory, Cambridge (now the MRC Laboratory of Molecular Biology), made a double helix model of DNA which changed the entire research scenario. They proposed the DNA structure based on previous research done by Ro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Province Of Saxony
The Province of Saxony (german: link=no, Provinz Sachsen), also known as Prussian Saxony () was a province of the Kingdom of Prussia and later the Free State of Prussia from 1816 until 1944. Its capital was Magdeburg. It was formed by the merger of various territories ceded or returned to Prussia in 1815 by the Congress of Vienna: most of the former northern territories of the Kingdom of Saxony (the remainder of which became part of Brandenburg or Silesia), the former French Principality of Erfurt, the Duchy of Magdeburg, the Altmark, the Principality of Halberstadt, and some other districts. The province was bounded by the Electorate of Hesse (the province of Hesse-Nassau after 1866), the Kingdom of Hanover (the province of Hanover after 1866) and the Duchy of Brunswick to the west, Hanover (again) to the north, Brandenburg to the north and east, Silesia to the south-east, and the rump kingdom of Saxony and the small Ernestine duchies to the south. Its shape was very irregular ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemist
A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties. Chemists carefully describe the properties they study in terms of quantities, with detail on the level of molecules and their component atoms. Chemists carefully measure substance proportions, chemical reaction rates, and other chemical properties. In Commonwealth English, pharmacists are often called chemists. Chemists use their knowledge to learn the composition and properties of unfamiliar substances, as well as to reproduce and synthesize large quantities of useful naturally occurring substances and create new artificial substances and useful processes. Chemists may specialize in any number of subdisciplines of chemistry. Materials scientists and metallurgists share much of the same education and skills with chemists. The work of chemists is often related to the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
