Eugen Baumann
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Eugen Baumann
Eugen Baumann (12 December 1846 – 3 November 1896) was a German chemist. He was one of the first people to create polyvinyl chloride (PVC), and, together with Carl Schotten, he discovered the Schotten-Baumann reaction. Life Baumann was born in Cannstatt, which is now part of Stuttgart. After he attended a gymnasium in Stuttgart, he was educated in the pharmacy of his father. During his time in Stuttgart, he attended the lectures of Hermann von Fehling at the University of Stuttgart. To broaden his education, he went to Lübeck and Gothenburg to work in pharmacies there. Later, he studied pharmacy at the University of Tübingen. He passed his first exam in 1870 and received his PhD in 1872 for work with Felix Hoppe-Seyler. He followed Hoppe-Seyler to the University of Straßburg where did his habilitation in 1876. The same year, Emil Heinrich Du Bois-Reymond offered him a position as the Head of the Chemistry Department of the Institute of Physiology in Berlin. In 1882, Bauman ...
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Bad Cannstatt
Bad Cannstatt, also called Cannstatt (until July 23, 1933) or Kannstadt (until 1900), is one of the outer stadtbezirke, or city boroughs, of Stuttgart in Baden-Württemberg, Germany. Bad Cannstatt is the oldest and most populous of Stuttgart's boroughs, and one of the most historically significant towns in the area of Stuttgart. The town is home to the Cannstatter Wasen and Cannstatter Volksfest beer festivals, the Mercedes-Benz Arena (VfB Stuttgart), the Hanns-Martin-Schleyer-Halle, and the Porsche-Arena. Name Bad Cannstatt's name originates from a ''Castra stativa'', Cannstatt Castrum, the massive Roman Castra that was erected on the hilly ridge in AD 90 to protect the valuable river crossing and local trade. In the past, Bad Cannstatt has been known as simply Cannstatt or ''Kannstatt'', ''Cannstadt'', ''Canstatt'', ''Kanstatt'', and ''Condistat''. Its name was changed to include "''Bad''" (german: Bath) to mention the town's spas on 23 July 1933. History Bad Cannstatt li ...
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Lübeck
Lübeck (; Low German also ), officially the Hanseatic City of Lübeck (german: Hansestadt Lübeck), is a city in Northern Germany. With around 217,000 inhabitants, Lübeck is the second-largest city on the German Baltic coast and in the state of Schleswig-Holstein, after its capital of Kiel, and is the 35th-largest city in Germany. The city lies in Holstein, northeast of Hamburg, on the mouth of the River Trave, which flows into the Bay of Lübeck in the borough of Travemünde, and on the Trave's tributary Wakenitz. The city is part of the Hamburg Metropolitan Region, and is the southwesternmost city on the Baltic, as well as the closest point of access to the Baltic from Hamburg. The port of Lübeck is the second-largest German Baltic port after the port of Rostock. The city lies in the Northern Low Saxon dialect area of Low German. Lübeck is famous for having been the cradle and the ''de facto'' capital of the Hanseatic League. Its city centre is Germany's most extens ...
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Thyroxine
File:Thyroid_system.svg, upright=1.5, The thyroid system of the thyroid hormones T3 and T4 rect 376 268 820 433 Thyroid-stimulating hormone rect 411 200 849 266 Thyrotropin-releasing hormone rect 297 168 502 200 Hypothalamus rect 66 216 386 256 Anterior pituitary gland rect 66 332 342 374 Negative feedback rect 308 436 510 475 Thyroid gland rect 256 539 563 635 Thyroid hormones rect 357 827 569 856 Catecholamine rect 399 716 591 750 Metabolism desc bottom-left Thyroid hormones are any hormones produced and released by the thyroid gland, namely triiodothyronine (T3) and thyroxine (T4). They are tyrosine-based hormones that are primarily responsible for regulation of metabolism. T3 and T4 are partially composed of iodine. A deficiency of iodine leads to decreased production of T3 and T4, enlarges the thyroid tissue and will cause the disease known as simple goitre. The major form of thyroid hormone in the blood is thyroxine (T4), whose half-life of around one week is longer th ...
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Anesthesia
Anesthesia is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia (relief from or prevention of pain), paralysis (muscle relaxation), amnesia (loss of memory), and unconsciousness. An individual under the effects of anesthetic drugs is referred to as being anesthetized. Anesthesia enables the painless performance of procedures that would otherwise cause severe or intolerable pain in a non-anesthetized individual, or would otherwise be technically unfeasible. Three broad categories of anesthesia exist: * General anesthesia suppresses central nervous system activity and results in unconsciousness and total lack of sensation, using either injected or inhaled drugs. * Sedation suppresses the central nervous system to a lesser degree, inhibiting both anxiety and creation of long-term memories without resulting in unconsciousness. * Regional and local anesthesia, which blo ...
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Thioketal
In organosulfur chemistry, a thioketal is the sulfur analogue of a ketal (), with one of the oxygen replaced by sulfur (as implied by the ''thio-'' prefix), giving the structure . A dithioketal has ''both'' oxygens replaced by sulfur (). Thioketals can be obtained by reacting ketones () or aldehydes () with thiols (). An oxidative cleavage mechanism has been proposed for dithioketals, which involves thioether oxidation, the formation of thionoiums, and hydrolysis, resulting in the formation of aldehyde and ketone products. Thioketal moieties are found to be responsive to reactive oxygen species In chemistry, reactive oxygen species (ROS) are highly reactive chemicals formed from diatomic oxygen (). Examples of ROS include peroxides, superoxide, hydroxyl radical, singlet oxygen, and alpha-oxygen. The reduction of molecular oxygen () p ... (ROS). In the presence of ROS, thioketals can be selectively cleaved. ROS successfully cleave heterobifunctional thioketal linkers, ...
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Thioacetal
In organosulfur chemistry, thioacetals are the sulfur (''thio-'') analogues of acetals (). There are two classes: the less-common monothioacetals, with the formula , and the dithioacetals, with the formula (symmetric dithioacetals) or (asymmetric dithioacetals). The symmetric dithioacetals are relatively common. They are prepared by condensation of thiols () or dithiols (two groups) with aldehydes (). These reactions proceed via the intermediacy of hemithioacetals (): #Thiol addition to give hemithioacetal: #::RSH + R'CH(O) -> R'CH(SR)OH #Thiol addition with loss of water to give dithioacetal: #::RSH + R'CH(OH)SR -> R'CH(SR)2 + H2O Such reactions typically employ either a Lewis acid or Brønsted acid as catalyst. Dithioacetals generated from aldehydes and either 1,2-ethanedithiol or 1,3-propanedithiol are especially common among this class of molecules for use in organic synthesis.P. Stütz And P. A. Stadler "3-alkylated And 3-acylated Indoles From A Common Precurs ...
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Tyrosine
-Tyrosine or tyrosine (symbol Tyr or Y) or 4-hydroxyphenylalanine is one of the 20 standard amino acids that are used by cells to synthesize proteins. It is a non-essential amino acid with a polar side group. The word "tyrosine" is from the Greek ''tyrós'', meaning '' cheese'', as it was first discovered in 1846 by German chemist Justus von Liebig in the protein casein from cheese. It is called tyrosyl when referred to as a functional group or side chain. While tyrosine is generally classified as a hydrophobic amino acid, it is more hydrophilic than phenylalanine. It is encoded by the codons UAC and UAU in messenger RNA. Functions Aside from being a proteinogenic amino acid, tyrosine has a special role by virtue of the phenol functionality. It occurs in proteins that are part of signal transduction processes and functions as a receiver of phosphate groups that are transferred by way of protein kinases. Phosphorylation of the hydroxyl group can change the activity of ...
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Amino Acid
Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although hundreds of amino acids exist in nature, by far the most important are the alpha-amino acids, which comprise proteins. Only 22 alpha amino acids appear in the genetic code. Amino acids can be classified according to the locations of the core structural functional groups, as Alpha and beta carbon, alpha- , beta- , gamma- or delta- amino acids; other categories relate to Chemical polarity, polarity, ionization, and side chain group type (aliphatic, Open-chain compound, acyclic, aromatic, containing hydroxyl or sulfur, etc.). In the form of proteins, amino acid '' residues'' form the second-largest component (water being the largest) of human muscles and other tissues. Beyond their role as residues in proteins, amino acids participate in a number of processes such as neurotransmitter transport and biosynthesis. It is thought that they played a key role in enabling l ...
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Aromaticity
In chemistry, aromaticity is a chemical property of cyclic ( ring-shaped), ''typically'' planar (flat) molecular structures with pi bonds in resonance (those containing delocalized electrons) that gives increased stability compared to saturated compounds having single bonds, and other geometric or connective non-cyclic arrangements with the same set of atoms. Aromatic rings are very stable and do not break apart easily. Organic compounds that are not aromatic are classified as aliphatic compounds—they might be cyclic, but only aromatic rings have enhanced stability. The term ''aromaticity'' with this meaning is historically related to the concept of having an aroma, but is a distinct property from that meaning. Since the most common aromatic compounds are derivatives of benzene (an aromatic hydrocarbon common in petroleum and its distillates), the word ''aromatic'' occasionally refers informally to benzene derivatives, and so it was first defined. Nevertheless, many ...
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Berichte Der Deutschen Chemischen Gesellschaft
''Chemische Berichte'' (usually abbreviated as ''Ber.'' or ''Chem. Ber.'') was a German-language scientific journal of all disciplines of chemistry founded in 1868. It was one of the oldest scientific journals in chemistry, until it merged with '' Recueil des Travaux Chimiques des Pays-Bas'' to form ''Chemische Berichte/Recueil'' in 1997. ''Chemische Berichte/Recueil'' was then merged with other European journals in 1998 to form ''European Journal of Inorganic Chemistry''. History Founded in 1868 as ''Berichte der Deutschen Chemischen Gesellschaft'' (, CODEN BDCGAS), it operated under this title until 1928 (Vol. 61). The journal was then split into: * ''Berichte der Deutschen Chemischen Gesellschaft, A: Vereins-Nachrichten'' (, CODEN BDCAAS), and * ''Berichte der Deutschen Chemischen Gesellschaft, B: Abhandlungen'' (, CODEN BDCBAD). Vol. 78 and 79 (1945–1946) were omitted and not published due to World War II. The journal was renamed ''Chemische Berichte'' (, CODEN CHBEAM) in ...
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Hermann Franz Moritz Kopp
Hermann Franz Moritz Kopp (30 October 1817 – 20 February 1892), German chemist, was born at Hanau, where his father, Johann Heinrich Kopp (1777–1858), a physician, was professor of chemistry, physics and natural history at the local lyceum. After attending the gymnasium of his native town, he studied at Marburg and Heidelberg, and then, attracted by the fame of Liebig, went in 1839 to Gießen, where he became a '' privatdozent'' in 1841, and professor of chemistry twelve years later. In 1864 he was called to Heidelberg in the same capacity, and he remained there till his death. Kopp devoted himself especially to physico-chemical inquiries, and in the history of chemical theory his name is associated with several of the most important correlations of the physical properties of substances with their chemical constitution. Much of his work was concerned with specific volumes, the conception of which he set forth in a paper published when he was only twenty-two years of age; ...
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Biological Chemistry (journal)
''Biological Chemistry'' is a peer-reviewed scientific journal focusing on biological chemistry. The journal is published by Walter de Gruyter and the current editor-in-chief is Bernhard Brüne. History The journal was established by Felix Hoppe-Seyler in 1877, under the name ''Zeitschrift für Physiologische Chemie'' (English: ''Journal of Physiological Chemistry''), and was edited by him until his death in 1895. The journal was subsequently renamed '' Hoppe-Seyler's Zeitschrift für Physiologische Chemie'' in 1896. Following Hoppe-Seyler, the journal was edited by his student and collaborator, the German biochemist and Nobel laureate Albrecht Kossel, until his death in 1927. In 1985 the journal was renamed as ''Biological Chemistry Hoppe-Seyler'', before obtaining its current title in 1996. Abstracting and indexing ''Biological Chemistry'' is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2014 impact factor The impact factor ...
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