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Deep Heat (Heat Rub)
The Mentholatum Company, Inc. is a maker of non-prescription health care products founded in 1889 by Albert Alexander Hyde in the United States. It was bought out by Rohto Pharmaceutical Co., a Japanese health care company, in 1988. The Mentholatum Company is known for its top three products, Mentholatum Ointment, Mentholatum Deep Heating Rub (branded as "Deep Heat" outside of the United States), and Mentholatum Lip Care. The Mentholatum Building in Buffalo, New York was listed on the National Register of Historic Places in 2017. History Beginning (1889-1935) The beginning of The Mentholatum Company started when Albert Alexander Hyde left the real estate market in 1889. With the collapse of the market, Hyde established a new partnership called The Yucca Company, located in Wichita, Kansas, which focused on manufacturing and marketing shaving creams, laundry soap, and toilet soap. The Yucca Company was the beginning of The Mentholatum Company. When The Yucca Company star ...
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Mentholatum Logo
The Mentholatum Company, Inc. is a maker of non-prescription health care products founded in 1889 by Albert Alexander Hyde in the United States. It was bought out by Rohto Pharmaceutical Co., a Japanese health care company, in 1988. The Mentholatum Company is known for its top three products, Mentholatum Ointment, Mentholatum Deep Heating Rub (branded as "Deep Heat" outside of the United States), and Mentholatum Lip Care. The Mentholatum Building in Buffalo, New York was listed on the National Register of Historic Places in 2017. History Beginning (1889-1935) The beginning of The Mentholatum Company started when Albert Alexander Hyde left the real estate market in 1889. With the collapse of the market, Hyde established a new partnership called The Yucca Company, located in Wichita, Kansas, which focused on manufacturing and marketing shaving creams, laundry soap, and toilet soap. The Yucca Company was the beginning of The Mentholatum Company. When The Yucca Company start ...
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Menthol
Menthol is an organic compound, more specifically a monoterpenoid, made synthetically or obtained from the oils of corn mint, peppermint, or other mints. It is a waxy, clear or white crystalline substance, which is solid at room temperature and melts slightly above. The main form of menthol occurring in nature is (−)-menthol, which is assigned the (1''R'',2''S'',5''R'') configuration. Menthol has local anesthetic and counterirritant qualities, and it is widely used to relieve minor throat irritation. Menthol also acts as a weak κ-opioid receptor agonist. Structure Natural menthol exists as one pure stereoisomer, nearly always the (1''R'',2''S'',5''R'') form (bottom left corner of the diagram below). The eight possible stereoisomers are: : In the natural compound, the isopropyl group is in the ''trans'' orientation to both the methyl and hydroxyl groups. Thus, it can be drawn in any of the ways shown: : The (+)- and (−)-enantiomers of menthol are the most stable among ...
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Phisoderm
Phisoderm is a skin detergent which assists persons who are allergic to soap and Phisohex, a detergent and sudsless cleanser which prevents the spread of infections. In the 1950s, both Phisoderm and Phisohex were manufactured by Winthrop Laboratories. Earlier, the product was made by Fairchild Brothers & Foster. Phisoderm was developed by B. Thurber Guild (1886–1958), a physician and pharmaceutical manufacturer. Guild practiced medicine in Boston, Massachusetts, and was a specialist in allergies.''Dr. B. Thurber Guild, Allergist, Was 72'', ''The New York Times'', June 17, 1958, pg. 29. The brand is currently owned by Mentholatum. Withdrawal from sale and reinstatement Both Phisoderm and Phisohex were removed by drugstores and retail outlet stores when the Food and Drug Administration halted the production and distribution of products containing more than 1% of hexachlorophene, in September 1972."Germicide Limit Stirs Confusion", ''The New York Times'', September 24, 1972, pg ...
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GlaxoSmithKline
GSK plc, formerly GlaxoSmithKline plc, is a British multinational pharmaceutical and biotechnology company with global headquarters in London, England. Established in 2000 by a merger of Glaxo Wellcome and SmithKline Beecham. GSK is the tenth largest pharmaceutical company and #294 on the 2022 ''Fortune'' Global 500, ranked behind other pharmaceutical companies China Resources, Sinopharm, Johnson & Johnson, Pfizer, Roche, AbbVie, Novartis, Bayer, and Merck. The company has a primary listing on the London Stock Exchange and is a constituent of the FTSE 100 Index. , it had a market capitalisation of £70 billion, the eighth largest on the London Stock Exchange. It has a secondary listing on the New York Stock Exchange. The company developed the first malaria vaccine, RTS,S, which it said in 2014 it would make available for five percent above cost. Legacy products developed at GSK include several listed in the World Health Organization's List of Essential Medicines, such ...
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Fletcher's Castoria
Fletcher's Castoria, now known as Fletcher's Laxative, is an oral syrup containing a stimulant laxative and ingredients to soothe the stomach. It is a product of The Mentholatum Company, Inc. History On May 12, 1868, the United States Patent Office granted a patent to Dr. Samuel Pitcher (1824-1907) of Barnstable, Massachusetts, for a cathartic composed of senna, sodium bicarbonate, essence of wintergreen, dandelion, sugar and water. The remedy was initially sold under the name Pitcher's Castoria. Over time the product formula has changed. In 1871, The Centaur Company was formed by Charles Henry Fletcher to purchase the rights to and manufacture Pitcher's Castoria. It was renamed Fletcher's Castoria. Castoria was the subject of one of the most significant campaigns in early mass advertising. Castoria ads from the 1870s through 1920s are still visible today (or at least were between the 1970s and 2005) on the buildings of New York. See and for photos. At the opening of the ...
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Orchard Park, New York
Orchard Park is a town in Erie County, New York. It is an outer ring suburb southeast of Buffalo. As of the 2010 census, the population was 29,054, representing an increase of 5.13% from the 2000 census figure. The town contains a village also named Orchard Park. Orchard Park is one of the "Southtowns" of Erie County and is best known as the site of Highmark Stadium, home of the National Football League's Buffalo Bills. History In 1803, Didymus C. Kinney and wife Phebe (Hartwell) purchased land and built a cabin in the southwest corner of the township, which has since been turned into a museum. The following year, a migration of Quaker settlers began. The town was separated from the town of Hamburg in 1850 and was first named "Ellicott", after Joseph Ellicott, an agent of the Holland Land Company. Within months, the name was changed to the town of "East Hamburgh". Around 1934, the town was renamed "Orchard Park" after its principal settlement. In the early 1900s, a large f ...
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Indonesia
Indonesia, officially the Republic of Indonesia, is a country in Southeast Asia and Oceania between the Indian and Pacific oceans. It consists of over 17,000 islands, including Sumatra, Java, Sulawesi, and parts of Borneo and New Guinea. Indonesia is the world's largest archipelagic state and the 14th-largest country by area, at . With over 275 million people, Indonesia is the world's fourth-most populous country and the most populous Muslim-majority country. Java, the world's most populous island, is home to more than half of the country's population. Indonesia is a presidential republic with an elected legislature. It has 38 provinces, of which nine have special status. The country's capital, Jakarta, is the world's second-most populous urban area. Indonesia shares land borders with Papua New Guinea, East Timor, and the eastern part of Malaysia, as well as maritime borders with Singapore, Vietnam, Thailand, the Philippines, Australia, Palau, and India ...
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China
China, officially the People's Republic of China (PRC), is a country in East Asia. It is the world's most populous country, with a population exceeding 1.4 billion, slightly ahead of India. China spans the equivalent of five time zones and borders fourteen countries by land, the most of any country in the world, tied with Russia. Covering an area of approximately , it is the world's third largest country by total land area. The country consists of 22 provinces, five autonomous regions, four municipalities, and two Special Administrative Regions (Hong Kong and Macau). The national capital is Beijing, and the most populous city and financial center is Shanghai. Modern Chinese trace their origins to a cradle of civilization in the fertile basin of the Yellow River in the North China Plain. The semi-legendary Xia dynasty in the 21st century BCE and the well-attested Shang and Zhou dynasties developed a bureaucratic political system to serve hereditary monarchies, or dyna ...
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Guangdong Province
Guangdong (, ), alternatively romanized as Canton or Kwangtung, is a coastal province in South China on the north shore of the South China Sea. The capital of the province is Guangzhou. With a population of 126.01 million (as of 2020) across a total area of about , Guangdong is the most populous province of China and the 15th-largest by area as well as the second-most populous country subdivision in the world (after Uttar Pradesh in India). Its economy is larger than that of any other province in the nation and the fifth largest sub-national economy in the world with a GDP (nominal) of 1.95 trillion USD (12.4 trillion CNY) in 2021. The Pearl River Delta Economic Zone, a Chinese megalopolis, is a core for high technology, manufacturing and foreign trade. Located in this zone are two of the four top Chinese cities and the top two Chinese prefecture-level cities by GDP; Guangzhou, the capital of the province, and Shenzhen, the first special economic zone in the count ...
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Zhongshan
Zhongshan (; ) is a prefecture-level city in the south of the Pearl River Delta in Guangdong province, China. As of the 2020 census, the whole city with 4,418,060 inhabitants is now part of the Guangzhou–Shenzhen conurbation with 65,565,622 inhabitants. The city-core subdistricts used to be called Shiqi or Shekki (). Zhongshan is one of the few Chinese cities to be named after a person. It was originally named Xiangshan (, "Fragrant Mountain"; Cantonese: ''Heung-saan''), but was renamed in 1925 in honor of Sun Yat-sen, who is known in China as "Sun Zhongshan". Sun was the founding father of the Republic of China who is also regarded positively by the People's Republic. He was born in Cuiheng village in Nanlang Township of what was then Xiangshan County. Names Until 1925, Zhongshan was generally known as Xiangshan or Heung-san (Siangshan) (), in reference to the many flowers that grew in the mountains nearby. The city was renamed in honor of Sun Yat-sen, who had adopted ...
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Osaka
is a designated city in the Kansai region of Honshu in Japan. It is the capital of and most populous city in Osaka Prefecture, and the third most populous city in Japan, following Special wards of Tokyo and Yokohama. With a population of 2.7 million in the 2020 census, it is also the largest component of the Keihanshin Metropolitan Area, which is the second-largest metropolitan area in Japan and the 10th largest urban area in the world with more than 19 million inhabitants. Osaka was traditionally considered Japan's economic hub. By the Kofun period (300–538) it had developed into an important regional port, and in the 7th and 8th centuries, it served briefly as the imperial capital. Osaka continued to flourish during the Edo period (1603–1867) and became known as a center of Japanese culture. Following the Meiji Restoration, Osaka greatly expanded in size and underwent rapid industrialization. In 1889, Osaka was officially established as a municipality. The construc ...
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William Merrell Vories
Merrell Vories Hitotsuyanagi (; born William Merrell Vories; October 28, 1880 – May 7, 1964) was an educator, architect, entrepreneur, Christian lay missionary, and founder of the Omi Mission. Born in the United States, he later became a naturalized Japanese citizen. Merrell lived and worked mainly in Shiga Prefecture in Japan. With only limited formal training as an architect, he founded an architectural office in Shiga which employed over thirty professional staff and was responsible for the design of well over 1000 residential, commercial, and church structures in Japan and occupied Korea, prior to the Second World War. Biography Vories was born in Leavenworth, Kansas in 1880. He graduated from Colorado College in 1904. At first, he hoped to be an architect, although he came to Japan in 1905 as an English-language teacher, with an intention to engage in Christian missionary work. While working as a teacher in Omihachiman, Shiga Prefecture, in 1908 he was dismissed from tea ...
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