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Cumulina
Cumulina (October 3, 1997-May 5, 2000), a mouse, was the first animal cloned from adult cells that survived to adulthood. She was cloned using the Honolulu technique developed by "Team Yana", the Ryuzo Yanagimachi research group at the former campus of the John A. Burns School of Medicine located at the University of Hawai'i at Mānoa. Cumulina was a brown '' Mus musculus'' or common house mouse. She was named after the cumulus cells surrounding the developing oocyte in the ovarian follicle in mice. Nuclei from these cells were put into egg cell devoid of their original nuclei in the Honolulu cloning technique. All other mice produced by the Yanagimachi lab are just known by a number. Cumulina was able to produce two healthy litters. She was retired after the second. Cumulina's preserved remains can be visited at the Institute for Biogenesis Research, a part of the John A. Burns School of Medicine laboratory, in Honolulu, Hawaii. Some of her descendants have been displayed ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ryuzo Yanagimachi
is a Japanese-born, American-based scientist. He has made numerous key contributions to the study of mammalian fertilization. He is a pioneer of assisted fertilization technologies such as in vitro fertilization and direct sperm injection into the egg (commonly called intracytoplasmic sperm injection or ICSI), which are widely used today in human infertility clinics throughout the world. He was also a pioneer in the cloning field. In 1997, his laboratory at the University of Hawaii at Manoa successfully cloned mice using the Honolulu technique. Early and later years Yanagimachi was born in Ebetsu and raised in Sapporo, Japan. He received a BS in zoology in 1952 and a DSc in animal embryology in 1960 both from Hokkaido University. Being unable to find a research position initially, he then worked as a high school teacher for two years. Yanagimachi applied for a post-doctoral position with Dr. M. C. Chang of the Worcester Foundation for Biomedical Research in Shrewsbury, Mass ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cloning
Cloning is the process of producing individual organisms with identical or virtually identical DNA, either by natural or artificial means. In nature, some organisms produce clones through asexual reproduction. In the field of biotechnology, cloning is the process of creating cloned organisms (copies) of Cell (biology), cells and of DNA fragments (molecular cloning). Etymology Coined by Herbert J. Webber, the term clone derives from the Ancient Greek word (), ''twig'', which is the process whereby a new plant is created from a twig. In botany, the term ''lusus'' was used. In horticulture, the spelling ''clon'' was used until the early twentieth century; the final ''e'' came into use to indicate the vowel is a "long o" instead of a "short o". Since the term entered the popular lexicon in a more general context, the spelling ''clone'' has been used exclusively. Natural cloning Cloning is a natural form of reproduction that has allowed life forms to spread for hundreds of millio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Commercial Animal Cloning
Commercial animal cloning is the cloning of animals for commercial purposes, currently, including livestock, competition camels and horses, pets, medical uses, endangered and extinct animals, as first demonstrated in 1996 for Dolly the sheep. Cloning methods Moving or copying all (or nearly all) genes from one animal to form a second, genetically nearly identical, animal is usually done through one of three methods: the Roslin technique, the Honolulu technique, and Artificial Twinning. The first two of these involve a process known as somatic cell nuclear transfer. In this process, an oocyte is taken from a surrogate mother and put through enucleation, a process that removes the nucleus from inside the oocyte. Somatic cells are then taken from the animal that is being cloned, transferred into the blank oocyte in order to provide genetic material, and fused with the oocyte using an electrical current. The oocyte is then activated and re-inserted into the surrogate mother. The en ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John A
Sir John Alexander Macdonald (January 10 or 11, 1815 – June 6, 1891) was the first prime minister of Canada, serving from 1867 to 1873 and from 1878 to 1891. The dominant figure of Canadian Confederation, he had a political career that spanned almost half a century. Macdonald was born in Scotland; when he was a boy his family immigrated to Kingston in the Province of Upper Canada (today in eastern Ontario). As a lawyer, he was involved in several high-profile cases and quickly became prominent in Kingston, which elected him in 1844 to the legislature of the Province of Canada. By 1857, he had become premier under the colony's unstable political system. In 1864, when no party proved capable of governing for long, Macdonald agreed to a proposal from his political rival, George Brown, that the parties unite in a Great Coalition to seek federation and political reform. Macdonald was the leading figure in the subsequent discussions and conferences, which resulted in the Brit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Hawaii At Manoa
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, the designation is reserved for colleges that have a graduate school. The word ''university'' is derived from the Latin ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". The first universities were created in Europe by Catholic Church monks. The University of Bologna (''Università di Bologna''), founded in 1088, is the first university in the sense of: *Being a high degree-awarding institute. *Having independence from the ecclesiastic schools, although conducted by both clergy and non-clergy. *Using the word ''universitas'' (which was coined at its foundation). *Issuing secular and non-secular degrees: grammar, rhetoric, logic, theology, canon law, notarial law.Hunt Janin: "The university ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mus Musculus
Mus or MUS may refer to: Abbreviations * MUS, the NATO country code for Mauritius * MUS, the IATA airport code for Minami Torishima Airport * MUS, abbreviation for the Centre for Modern Urban Studies on Campus The Hague, Leiden University, Netherlands * MUS, abbreviation for Medically unexplained physical symptoms * MUS, abbreviation for the Memphis University School * MUS, abbreviation for the Movimiento Unión Soberanista * MUS, abbreviation for Multiple-use water supply system, a low-cost, equitable water supply systems * Mus, abbreviation for Musca, a southern constellation * mus, ISO-639 code for the Muscogee language * Mus., abbreviation used in music degrees such as B.Mus. and M.Mus. * MUs, or million units of energy, used in India for a gigawatt hour People * Anders Mus (fl. 1501–1535), Danish civil servant in Norway * Conny Mus (1950–2010), Dutch journalist, best known as a correspondent for ''RTL Nieuws'' in Israel and the Middle East * Gus Mus (born 1944), I ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cumulus Cell
The cumulus oophorus, (discus proligerus), is a cluster of cells that surround the oocyte both in the ovarian follicle and after ovulation. In the antral follicle, it may be regarded as an extension of the membrana granulosa. The innermost layer of these cells is the corona radiata. This layer of cells must be penetrated by spermatozoa for fertilization to occur. Functions Functions of the cumulus oophorus include coordination of follicular development and oocyte maturation. Mechanisms of the latter include stimulation of amino acid transport and sterol biosynthesis and regulation of oocyte gene transcription. It also provides energy substrates for oocyte meiotic resumption and promotes glycolysis. Cumulus oophorus cells contribute heavily to the maturation and eventual fertilization of an oocyte. As a follicle grows in size and the antrum develops, more layers of cumulus oophorus cells accumulate around the oocyte to aid in the acrosome reaction and sperm penetration into th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oocyte
An oocyte (, ), oöcyte, or ovocyte is a female gametocyte or germ cell involved in reproduction. In other words, it is an immature ovum, or egg cell. An oocyte is produced in a female fetus in the ovary during female gametogenesis. The female germ cells produce a primordial germ cell (PGC), which then undergoes mitosis, forming oogonia. During oogenesis, the oogonia become primary oocytes. An oocyte is a form of genetic material that can be collected for cryoconservation. Formation The formation of an oocyte is called oocytogenesis, which is a part of oogenesis. Oogenesis results in the formation of both primary oocytes during fetal period, and of secondary oocytes after it as part of ovulation. Characteristics Cytoplasm Oocytes are rich in cytoplasm, which contains yolk granules to nourish the cell early in development. Nucleus During the primary oocyte stage of oogenesis, the nucleus is called a germinal vesicle. The only normal human type of secondary oocyte has t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ovarian Follicle
An ovarian follicle is a roughly spheroid cellular aggregation set found in the ovaries. It secretes hormones that influence stages of the menstrual cycle. At the time of puberty, women have approximately 200,000 to 300,000 follicles, each with the potential to release an egg cell (ovum) at ovulation for fertilization. These eggs are developed once every menstrual cycle with around 450–500 being ovulated during a woman's reproductive lifetime. Structure Ovarian follicles are the basic units of female reproductive biology. Each of them contains a single oocyte (immature ovum or egg cell). These structures are periodically initiated to grow and develop, culminating in ovulation of usually a single competent oocyte in humans. They also consist of granulosa cells and theca of follicle. Oocyte Once a month, one of the ovaries releases a mature egg (ovum), known as an oocyte. The nucleus of such an oocyte is called a '' germinal vesicle (see picture).'' Cumulus oophorus Cumulu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bishop Museum
The Bernice Pauahi Bishop Museum, designated the Hawaii State Museum of Natural and Cultural History, is a museum of history and science in the historic Kalihi district of Honolulu on the Hawaiian island of Oʻahu. Founded in 1889, it is the largest museum in Hawaiʻi and has the world's largest collection of Polynesian cultural artifacts and natural history specimens. Besides the comprehensive exhibits of Hawaiian cultural material, the museum's total holding of natural history specimens exceeds 24 million, of which the entomological collection alone represents more than 13.5 million specimens (making it the third-largest insect collection in the United States). The '' Index Herbariorum'' code assigned to Herbarium Pacificum of this museum is BISH and this abbreviation is used when citing housed herbarium specimens. The museum complex is home to the Richard T. Mamiya Science Adventure Center. History Establishment Charles Reed Bishop (1822–1915), a businessman and philant ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Museum Of Science And Industry (Chicago)
The Museum of Science and Industry (MSI) is a science museum located in Chicago, Illinois, in Jackson Park, in the Hyde Park neighborhood between Lake Michigan and The University of Chicago. It is housed in the former ''Palace of Fine Arts'' from the 1893 World's Columbian Exposition. Initially endowed by Julius Rosenwald, the Sears, Roebuck and Company president and philanthropist, it was supported by the Commercial Club of Chicago and opened in 1933 during the Century of Progress Exposition. Among the museum's exhibits are a full-size replica coal mine, captured during World War II, a model railroad, the command module of Apollo 8, and the first diesel-powered streamlined stainless-steel passenger train (''Pioneer Zephyr''). History The Palace of Fine Arts (also known as the Fine Arts Building) at the 1893 World's Columbian Exposition was designed by Charles B. Atwood for D. H. Burnham & Co. During the fair, the palace displayed paintings, prints, drawing, sculpture, an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1997 Animal Births
File:1997 Events Collage.png, From left, clockwise: The movie set of ''Titanic'', the highest-grossing movie in history at the time; ''Harry Potter and the Philosopher's Stone'', is published; Comet Hale-Bopp passes by Earth and becomes one of the most observed comets of the 20th century; Golden Bauhinia Square, where sovereignty of Hong Kong is handed over from the United Kingdom to the People's Republic of China; the 1997 Central European flood kills 114 people in the Czech Republic, Poland, and Germany; Korean Air Flight 801 crashes during heavy rain on Guam, killing 229; Mars Pathfinder and Sojourner land on Mars; flowers left outside Kensington Palace following the death of Diana, Princess of Wales, in a car crash in Paris., 300x300px, thumb rect 0 0 200 200 Titanic (1997 film) rect 200 0 400 200 Harry Potter rect 400 0 600 200 Comet Hale-Bopp rect 0 200 300 400 Death of Diana, Princess of Wales rect 300 200 600 400 Handover of Hong Kong rect 0 400 200 600 Mars Pathfinder r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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