Ryuzo Yanagimachi
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Ryuzo Yanagimachi
is a Japanese-born, American-based scientist. He has made numerous key contributions to the study of mammalian fertilization. He is a pioneer of assisted fertilization technologies such as in vitro fertilization and direct sperm injection into the egg (commonly called intracytoplasmic sperm injection or ICSI), which are widely used today in human infertility clinics throughout the world. He was also a pioneer in the cloning field. In 1997, his laboratory at the University of Hawaii at Manoa successfully cloned mice using the Honolulu technique. Early and later years Yanagimachi was born in Ebetsu and raised in Sapporo, Japan. He received a BS in zoology in 1952 and a DSc in animal embryology in 1960 both from Hokkaido University. Being unable to find a research position initially, he then worked as a high school teacher for two years. Yanagimachi applied for a post-doctoral position with Dr. M. C. Chang of the Worcester Foundation for Biomedical Research in Shrewsbury, Mass ...
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Ebetsu, Hokkaido
is a city in Ishikari Subprefecture, Hokkaido, Japan. History Ebetsu was settled originally by Japanese people in 1871, who came from the Miyagi Prefecture on Honshu. In 1878, tondenhei began moving into the area. When the Meiji Government, in 1878, designated Hokkaido as part of Japan, settlers began to flood the area. Ebetsu earned township status in 1916 and city status in 1954. During the 1960s and 1970s, a burgeoning population in Sapporo caused the population in Ebetsu to concurrently boom. In 1991, the city reached 100,000 people. The name Ebetsu is derived from the Ainu name of the Chitose River which flows into the Ishikari River in the city. According to John Batchelor in his "An Ainu-English Dictionary" (chapter 1, section V: Place Names Considered) the Ainu language name was E-pet or "humour river" based on its murky colour. Demographics As of May 1, 2017, the city has an estimated population of 119,086, with 56,325 households, and a population density of 630 ...
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The Honolulu Advertiser
''The Honolulu Advertiser'' was a daily newspaper published in Honolulu, Hawaii. At the time publication ceased on June 6, 2010, it was the largest daily newspaper in the American state of Hawaii. It published daily with special Sunday and Internet editions. ''The Honolulu Advertiser'' was the parent publisher of ''Island Weekly'', ''Navy News'', ''Army Weekly'', ''Ka Nupepa People'', ''West Oahu People'', ''Leeward People'', ''East Oahu People'', ''Windward People'', ''Metro Honolulu People'', and ''Honolulu People'' small, community-based newspapers for the public. ''The Honolulu Advertiser'' has had a succession of owners since it began publishing in 1856 under the name the ''Pacific Commercial Advertiser''. On February 25, 2010, Black Press, which owned the '' Honolulu Star-Bulletin'', purchased ''The Honolulu Advertiser'' from Gannett Pacific Corporation, which acquired the ''Advertiser'' in 1992 after it had sold the ''Star-Bulletin'' to another publisher that later sold ...
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University Of Pavia
The University of Pavia ( it, Università degli Studi di Pavia, UNIPV or ''Università di Pavia''; la, Alma Ticinensis Universitas) is a university located in Pavia, Lombardy, Italy. There was evidence of teaching as early as 1361, making it one of the oldest universities in the world. It was the sole university in Milan and the greater Lombardy region until the end of the 19th century. In 2022 the University was recognized by the Times Higher Education among the top 10 in Italy and among the 300 best in the world. Currently, it has 18 departments and 9 faculties. It does not have a main campus; its buildings and facilities are scattered around the city, which is in turn called "a city campus." The university caters to more than 20,000 students who come from Italy and all over the world. The university offers more than 80 undergraduate programs; over 40 master programs, and roughly 20 doctoral programs (including 8 in English). About 1,500 students who enter the university every ...
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Sapienza University Of Rome
The Sapienza University of Rome ( it, Sapienza – Università di Roma), also called simply Sapienza or the University of Rome, and formally the Università degli Studi di Roma "La Sapienza", is a Public university, public research university located in Rome, Italy. It is one of the List of largest universities by enrollment, largest European universities by enrollments and List of oldest universities in continuous operation, one of the oldest in history, founded in 1303. The university is one of the most prestigious Italian universities in the world, commonly ranking first in national rankings and in Southern Europe. In 2018, 2019, 2021 and 2022 it ranked first in the world for classics and ancient history. Most of the Italian ruling class studied at the Sapienza. The Sapienza has educated numerous notable alumni, including many List of Nobel laureates, Nobel laureates, President of the European Parliament, Presidents of the European Parliament and European Commissioners, heads ...
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International Prize For Biology
The is an annual award for "outstanding contribution to the advancement of research in fundamental biology." The Prize, although it is not always awarded to a biologist, is one of the most prestigious honours a natural scientist can receive. There are no restrictions on the nationality of the recipient. Past laureates include John B. Gurdon, Motoo Kimura, Edward O. Wilson, Ernst Mayr, Thomas Cavalier-Smith, Yoshinori Ohsumi and many other great biologists in the world. Information The International Prize of Biology was created in 1985 to commemorate the 60-year reign of Emperor Shōwa of Japan and his longtime interest in and support of "Biology." The selection and award of the prize is managed by the Japan Society for the Promotion of Science. The laureate is awarded a beautiful medal, 10 million yen, and an international symposium on the scientist's area of research is held in Tokyo. The prize ceremony is held in the presence of Emperor of Japan. The first International Pri ...
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Fulbright Program
The Fulbright Program, including the Fulbright–Hays Program, is one of several United States Cultural Exchange Programs with the goal of improving intercultural relations, cultural diplomacy, and intercultural competence between the people of the United States and other countries, through the exchange of persons, knowledge, and skills. Via the program, competitively-selected American citizens including students, scholars, teachers, professionals, scientists, and artists may receive scholarships or grants to study, conduct research, teach, or exercise their talents abroad; and citizens of other countries may qualify to do the same in the United States. The program was founded by United States Senator J. William Fulbright in 1946 and is considered to be one of the most widely recognized and prestigious scholarships in the world. The program provides approximately 8,000 grants annually – roughly 1,600 to U.S. students, 1,200 to U.S. scholars, 4,000 to foreign students, 900 to f ...
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Pluripotent Stem Cells
Pluripotency: These are the cells that can generate into any of the three Germ layers which imply Endodermal, Mesodermal, and Ectodermal cells except tissues like the placenta. According to Latin terms, Pluripotentia means the ability for many things. We can generate Induced Pluripotent cells by using the Induced pluripotency technique by triggering or expressing the genes or the transcription factors of the normal somatic cells. They are abbreviated as iPSC or IPS. We can forcefully express the transcription factors like  Oct4, Sox2, Klf4, and c-Myc of a non-pluripotent cell and convert them into a stem cell. This procedure is first studied in a Mouse fibroblast cell in 2006 and followed the same instructions in developing a Human pluripotent cell from a Human epidermal fibroblast cell. The technique is called Regeneration. Though the iPSC has similar properties to embryonic stem cells they were never approved for clinical stage research because they are highly Tumerogenic, hav ...
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Ravan Press
Ravan Press, established in 1972 by Peter Ralph Randall, Danie van Zyl, and Beyers Naudé, was a South African anti-apartheid publishing house.Ravan Press
in Michael F. Suarez, S.J. and H. R. Woudhuysen, ''The Oxford Companion to the Book'', online ed., 2010.
Ravan Press was initially established to print the reports of the South African Study Project of Christianity in Apartheid Society (Spro-Cas). In 1974 it became a donor-funded oppositional publishing house, specializing in anti-apartheid literature. In 1984, following its release of 's novel ''Fools and Other Stories'' (

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In Vitro Fertilization
In vitro fertilisation (IVF) is a process of fertilisation where an egg is combined with sperm in vitro ("in glass"). The process involves monitoring and stimulating an individual's ovulatory process, removing an ovum or ova (egg or eggs) from their ovaries and letting sperm fertilise them in a culture medium in a laboratory. After the fertilised egg (zygote) undergoes embryo culture for 2–6 days, it is transferred by catheter into the uterus, with the intention of establishing a successful pregnancy. IVF is a type of assisted reproductive technology used for infertility treatment, gestational surrogacy, and, in combination with pre-implantation genetic testing, avoiding transmission of genetic conditions. A fertilised egg from a donor may implant into a surrogate's uterus, and the resulting child is genetically unrelated to the surrogate. Some countries have banned or otherwise regulate the availability of IVF treatment, giving rise to fertility tourism. Restrictions ...
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Zona Pellucida
The zona pellucida (plural zonae pellucidae, also egg coat or pellucid zone) is a specialized extracellular matrix that surrounds the plasma membrane of mammalian oocytes. It is a vital constitutive part of the oocyte. The zona pellucida first appears in unilaminar primary oocytes. It is secreted by both the oocyte and the ovarian follicles. The zona pellucida is surrounded by the Corona radiata (embryology), corona radiata. The corona is composed of cells that care for the egg when it is emitted from the ovary. This structure binds spermatozoa, and is required to initiate the acrosome reaction. In the mouse (the best characterised mammalian system), the zona glycoprotein, ZP3, is responsible for sperm binding, adhering to proteins on the sperm plasma membrane. ZP3 is then involved in the induction of the acrosome reaction, whereby a spermatozoon releases the contents of the acrosome, acrosomal vesicle. The exact characterisation of what occurs in other species has become more ...
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Micropyle (zoology)
A micropyle is a pore in the membrane covering the ovum, through which a sperm enters. Micropyles are also found in sporozoites of some digenetic microorganisms such as ''Plasmodium'' at the anterior part of the cell that ultimately leads towards the apical cap. Examples of other organisms that have micropyles are the ''Bombyx mandarina'' and the ''Ceratitis capitata ''Ceratitis capitata'', commonly known as the Mediterranean fruit fly or medfly, is a yellow-and-brown fly native to sub-Saharan Africa. It has no near relatives in the Western Hemisphere and is considered to be one of the most destructive frui ...''. References Reproduction {{animal-anatomy-stub ...
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Chemotaxis
Chemotaxis (from '' chemo-'' + ''taxis'') is the movement of an organism or entity in response to a chemical stimulus. Somatic cells, bacteria, and other single-cell or multicellular organisms direct their movements according to certain chemicals in their environment. This is important for bacteria to find food (e.g., glucose) by swimming toward the highest concentration of food molecules, or to flee from poisons (e.g., phenol). In multicellular organisms, chemotaxis is critical to early development (e.g., movement of sperm towards the egg during fertilization) and development (e.g., migration of neurons or lymphocytes) as well as in normal function and health (e.g., migration of leukocytes during injury or infection). In addition, it has been recognized that mechanisms that allow chemotaxis in animals can be subverted during cancer metastasis. The aberrant chemotaxis of leukocytes and lymphocytes also contribute to inflammatory diseases such as atherosclerosis, asthma, and arthr ...
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