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Black Queen Cell Virus
The black queen cell virus (BQCV) is a virus that infects honey bees, specifically ''Apis mellifera'', ''Apis florea'', and ''Apis dorsata''. Infection of the latter two species is more recent and can be attributed to genetic similarity and geographical closeness. It is important to learn about this virus because it is one of the most common bee viruses and bees are the most important pollinators. The agricultural industry depends on the bee's pollination to increase its economic value. Description Black queen cell virus was originally described in 1977, but its genome was not sequenced until 2000. BQCV can currently be found most commonly in Australia and parts of South Africa. BQCV visibly affects the pupae of queen bees, causing them first to turn yellow and then black, and eventually die. These pupae come from queen bees that seem healthy and show no symptoms of being infected with this virus, as it only manifests itself with visible symptoms in the larvae. Although only the ...
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Virus
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898,Dimmock p. 4 more than 9,000 virus species have been described in detail of the millions of types of viruses in the environment. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent particles, or ''virions'', consisting of (i) the genetic material, i. ...
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Vaccine
A vaccine is a biological Dosage form, preparation that provides active acquired immunity to a particular infectious disease, infectious or cancer, malignant disease. The safety and effectiveness of vaccines has been widely studied and verified. A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or Antigen, killed forms of the microbe, its toxins, or one of its surface proteins. The agent stimulates the body's immune system to recognize the agent as a threat, destroy it, and to further recognize and destroy any of the microorganisms associated with that agent that it may encounter in the future. Vaccines can be prophylaxis, prophylactic (to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen), or therapeutic vaccines, therapeutic (to fight a disease that has already occurred, such as cancer vaccine, cancer).
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Major Capsid Protein VP1
Major capsid protein VP1 is a viral protein that is the main component of the polyomavirus capsid. VP1 monomers are generally around 350 amino acids long and are capable of self-assembly into an icosahedral structure consisting of 360 VP1 molecules organized into 72 pentamers. VP1 molecules possess a surface binding site that interacts with sialic acids attached to glycans, including some gangliosides, on the surfaces of cells to initiate the process of viral infection. The VP1 protein, along with capsid components VP2 and VP3, is expressed from the "late region" of the circular viral genome. Structure VP1 is the major structural component of the polyomavirus icosahedral capsid, which has T=7 symmetry and a diameter of 40-45 nm. The capsid contains three proteins; VP1 is the primary component and forms a 360-unit outer capsid layer composed of 72 pentamers. The other two components, VP2 and VP3, have high sequence similarity to each other, with VP3 truncated at the N- ...
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Capsid
A capsid is the protein shell of a virus, enclosing its genetic material. It consists of several oligomeric (repeating) structural subunits made of protein called protomers. The observable 3-dimensional morphological subunits, which may or may not correspond to individual proteins, are called capsomeres. The proteins making up the capsid are called capsid proteins or viral coat proteins (VCP). The capsid and inner genome is called the nucleocapsid. Capsids are broadly classified according to their structure. The majority of the viruses have capsids with either helical or icosahedral structure. Some viruses, such as bacteriophages, have developed more complicated structures due to constraints of elasticity and electrostatics. The icosahedral shape, which has 20 equilateral triangular faces, approximates a sphere, while the helical shape resembles the shape of a spring, taking the space of a cylinder but not being a cylinder itself. The capsid faces may consist of one or more ...
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Aparavirus
''Aparavirus'' is a genus of viruses in the order ''Picornavirales'', in the family ''Dicistroviridae''. Invertebrates, honeybee, and bumblebees serve as natural hosts. There are six species in this genus. Diseases associated with this genus include: ABPV: paralysis. This virus plays a role in sudden collapse of honey bee colonies infested with the parasitic mite varroa destructor. Taxonomy The genus contains the following species: *''Acute bee paralysis virus'' *''Israeli acute paralysis virus'' *''Kashmir bee virus Diseases of the honey bee or abnormal hive conditions include: Pests and parasites ''Varroa'' mites ''Varroa destructor'' and ''V. jacobsoni'' are parasitic mites that feed on the fat bodies of adult, pupal and larval bees. When the hive ...'' *'' Mud crab virus'' *'' Solenopsis invicta virus-1'' *'' Taura syndrome virus'' Structure Viruses in ''Aparavirus'' are non-enveloped, with icosahedral geometries, and T=pseudo3 symmetry. The diameter is around 30 ...
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Cripavirus
''Cripavirus'' is a genus of viruses in the order ''Picornavirales'', in the family ''Dicistroviridae''. Invertebrates serve as natural hosts. There are four species in this genus. Diseases associated with this genus include: DCV: increased reproductive potential; extremely pathogenic when injected with high associated mortality; CrPV: paralysis and death. These viruses can produce proteins directly from their RNA genome upon entering a cell; and therefore, does not require an RNA polymerase packaged in with it, as this may be produced from the genome after entering the cell.International Committee on the Taxonomy of Viruses
The name of the cripavirus family originates from its most famous member the Cricket Paralysis Virus. Which was made famous by its rather unusual < ...
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Arthropod
Arthropods (, (gen. ποδός)) are invertebrate animals with an exoskeleton, a Segmentation (biology), segmented body, and paired jointed appendages. Arthropods form the phylum Arthropoda. They are distinguished by their jointed limbs and Arthropod cuticle, cuticle made of chitin, often Mineralization (biology), mineralised with calcium carbonate. The arthropod body plan consists of segments, each with a pair of appendages. Arthropods are bilaterally symmetrical and their body possesses an exoskeleton, external skeleton. In order to keep growing, they must go through stages of moulting, a process by which they shed their exoskeleton to reveal a new one. Some species have wings. They are an extremely diverse group, with up to 10 million species. The haemocoel, an arthropod's internal cavity, through which its haemolymph – analogue of blood – circulates, accommodates its interior Organ (anatomy), organs; it has an open circulatory system. Like their exteriors, the internal or ...
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Marnaviridae
''Marnaviridae'' is a family of positive-stranded RNA viruses in the order ''Picornavirales''. The first species of this family that was isolated is ''Heterosigma akashiwo RNA virus'' (HaRNAV) in the genus '' Marnavirus'', that infects the toxic bloom-forming Raphidophyte alga, ''Heterosigma akashiwo''. Using a sequence-based framework an additional twenty marine RNA viruses have been added to the family. HaRNAV was isolated from water collected in the Strait of Georgia in British Columbia, Canada, from a concentrated virus assemblage using the host ''Heterosigma akashiwo'' (NEPCC 522). It must not be confused with two other unrelated viruses that infect this host, ''Heterosigma akashiwo virus 01'' (HaV-1, isolate: HaV53) in the genus ''Raphidovirus'', and '' Heterosigma akashiwo Nuclear Inclusion Virus'' (HaNIV). Taxonomy The family contains the following seven genera: *'' Bacillarnavirus'' *'' Kusarnavirus'' *'' Labyrnavirus'' *'' Locarnavirus'' *'' Marnavirus'' *'' Sal ...
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Dicistroviridae
''Dicistroviridae'' is a family of viruses in the order ''Picornavirales''. Invertebrates, including aphids, leafhoppers, flies, bees, ants, and silkworms, serve as natural hosts. There are 15 species in this family, assigned to three genera. Diseases associated with this family include: DCV: increased reproductive potential. extremely pathogenic when injected with high associated mortality. CrPV: paralysis and death. Taxonomy Although many dicistroviruses were initially placed in the ''Picornaviridae'', they have since been reclassified into their own family. The name (Dicistro) is derived from the characteristic dicistronic arrangement of the genome. This family is a member of the Order ''Picornavirales'' (along with the families ''Iflaviridae'', ''Picornaviridae'', and ''Secoviridae'' and '' Marnaviridae''). Within this order, the gene order is the gene order of the nonstructural proteins Hel(helicase)-Pro(protease)-RdRp(polymerase). The ''Dicistroviridae'' can be disting ...
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Comovirinae
''Comovirinae'' is a subfamily of viruses in the order ''Picornavirales'', in the family ''Secoviridae''; its genera were formerly classified in the family ''Comoviridae''. Plants serve as natural hosts. There are 62 species in this subfamily, assigned to 3 genera. Taxonomy The genera ''Comovirus'', ''Nepovirus'' and ''Fabavirus'' were classified into the family ''Comoviridae'' in 1993. This family was classified as part of the order ''Picornavirales'' when this order was created (2008), and its genera were reclassified as the subfamily ''Comovirinae'' of the family ''Secoviridae'' in 2009.ICTV Taxonomy History for Comovirinae
accessed on line Nov. 20, 2015. The subfamily contains the following genera: * ''