Aplidium Albicans
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Aplidium Albicans
''Aplidium albicans'' is a toxic sea squirt native to the Mediterranean Sea. Range Native to the Mediterranean Sea. Population density is sparse in its native range. Toxins ''A. albicans'' contains aplidine (aplidin, plitidepsin), found by Steiner et al 2015 and Borjan et al 2015 to be a cytotoxin (due to its apoptotic effect) and antiangiogenic. The toxin is structurally and functionally almost identical to toxins produced by the genus ''Tistrella'' of marine bacteria. Aquaculture Aquaculture of ''A. albicans'' has not been economically feasible . References

{{Tunicata-stub Enterogona Poisonous animals ...
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Henri Milne-Edwards
Henri Milne-Edwards (23 October 1800 – 29 July 1885) was an eminent French zoologist. Biography Henri Milne-Edwards was the 27th child of William Edwards, an English planter and colonel of the militia in Jamaica and Elisabeth Vaux, a Frenchwoman. Henri was born in Bruges, in present-day Belgium, where his parents had retired; Bruges was then a part of the newborn French Republic. His father had been jailed for several years for helping some Englishmen in their escape to their country. Henri spent most of his life in France. He was brought up in Paris by his older brother Guillaume Frederic Edwards (1777–1842), a distinguished physiologist and ethnologist. His father was released after the fall of Napoleon. The whole family then moved to Paris. At first he turned his attention to medicine, in which he graduated as an MD at Paris in 1823. His passion for natural history soon prevailed, and he gave himself up to the study of the lower forms of animal life. He became a stude ...
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Springer Reference
Springer or springers may refer to: Publishers * Springer Science+Business Media, aka Springer International Publishing, a worldwide publishing group founded in 1842 in Germany formerly known as Springer-Verlag. ** Springer Nature, a multinational academic publishing group created by the merger of Springer Science+Business Media, Nature Publishing Group, Palgrave Macmillan, and Macmillan Education * Axel Springer SE, an important conservative German publishing house, including several newspapers * Springer Publishing Company, an American publishing company of academic journals and books, focusing on public health and the like Places ;United States * Springer, New Mexico * Springer, Oklahoma * Springer Mountain Springer Mountain is a mountain located in the Chattahoochee National Forest on the border of Fannin and Gilmer counties. Located in the Blue Ridge Mountains in northern Georgia, the mountain has an elevation of about . Springer Mountain serves ..., southern termin ...
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Aquaculture
Aquaculture (less commonly spelled aquiculture), also known as aquafarming, is the controlled cultivation ("farming") of aquatic organisms such as fish, crustaceans, mollusks, algae and other organisms of value such as aquatic plants (e.g. lotus). Aquaculture involves cultivating freshwater, brackish water and saltwater populations under controlled or semi-natural conditions, and can be contrasted with commercial fishing, which is the harvesting of wild fish. Mariculture, commonly known as marine farming, refers specifically to aquaculture practiced in seawater habitats and lagoons, opposed to in freshwater aquaculture. Pisciculture is a type of aquaculture that consists of fish farming to obtain fish products as food. Aquaculture can also be defined as the breeding, growing, and harvesting of fish and other aquatic plants, also known as farming in water. It is an environmental source of food and commercial product which help to improve healthier habitats and used to recon ...
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Tistrella
''Tistrella'' is a bacterial genus from the family of Rhodospirillaceae. ''Tistrella'' produces didemnin Didemnins are cyclic depsipeptide compounds isolated from a tunicate (ascidian, or sea-squirt) of the genus '' Trididemnum'' (family of Didemnidæ) that were collected in the Caribbean Sea. They were first isolated in 1978 at the University of ...s. References Further reading * * Rhodospirillales Bacteria genera {{Alphaproteobacteria-stub ...
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Antiangiogenic
An angiogenesis inhibitor is a substance that inhibits the growth of new blood vessels (angiogenesis). Some angiogenesis inhibitors are endogenous and a normal part of the body's control and others are obtained exogenously through pharmaceutical drugs or diet. While angiogenesis is a critical part of wound healing and other favorable processes, certain types of angiogenesis are associated with the growth of malignant tumors. Thus angiogenesis inhibitors have been closely studied for possible cancer treatment. Angiogenesis inhibitors were once thought to have potential as a " silver bullet" treatment applicable to many types of cancer, but the limitations of anti-angiogenic therapy have been shown in practice. Nonetheless, inhibitors are used to effectively treat cancer, macular degeneration in the eye, and other diseases that involve a proliferation of blood vessels. Mechanism of action When a tumor stimulates the growth of new vessels, it is said to have undergone an 'an ...
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Elsevier
Elsevier () is a Dutch academic publishing company specializing in scientific, technical, and medical content. Its products include journals such as ''The Lancet'', ''Cell'', the ScienceDirect collection of electronic journals, '' Trends'', the '' Current Opinion'' series, the online citation database Scopus, the SciVal tool for measuring research performance, the ClinicalKey search engine for clinicians, and the ClinicalPath evidence-based cancer care service. Elsevier's products and services also include digital tools for data management, instruction, research analytics and assessment. Elsevier is part of the RELX Group (known until 2015 as Reed Elsevier), a publicly traded company. According to RELX reports, in 2021 Elsevier published more than 600,000 articles annually in over 2,700 journals; as of 2018 its archives contained over 17 million documents and 40,000 e-books, with over one billion annual downloads. Researchers have criticized Elsevier for its high profit marg ...
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Apoptotic
Apoptosis (from grc, ἀπόπτωσις, apóptōsis, 'falling off') is a form of programmed cell death that occurs in multicellular organisms. Biochemical events lead to characteristic cell changes (morphology) and death. These changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, DNA fragmentation, and mRNA decay. The average adult human loses between 50 and 70 billion cells each day due to apoptosis. For an average human child between eight and fourteen years old, approximately twenty to thirty billion cells die per day. In contrast to necrosis, which is a form of traumatic cell death that results from acute cellular injury, apoptosis is a highly regulated and controlled process that confers advantages during an organism's life cycle. For example, the separation of fingers and toes in a developing human embryo occurs because cells between the digits undergo apoptosis. Unlike necrosis, apoptosis produces cell fragments called apoptotic bod ...
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Cytotoxin
Cytotoxicity is the quality of being toxic to cells. Examples of toxic agents are an immune cell or some types of venom, e.g. from the puff adder (''Bitis arietans'') or brown recluse spider (''Loxosceles reclusa''). Cell physiology Treating cells with the cytotoxic compound can result in a variety of cell fates. The cells may undergo necrosis, in which they lose membrane integrity and die rapidly as a result of cell lysis. The cells can stop actively growing and dividing (a decrease in cell viability), or the cells can activate a genetic program of controlled cell death (apoptosis). Cells undergoing necrosis typically exhibit rapid swelling, lose membrane integrity, shut down metabolism, and release their contents into the environment. Cells that undergo rapid necrosis in vitro do not have sufficient time or energy to activate apoptotic machinery and will not express apoptotic markers. Apoptosis is characterized by well defined cytological and molecular events including a change i ...
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Cham, Switzerland
Cham is a municipality in the canton of Zug in Switzerland. Location Cham is located on the northern shore of Lake Zug, northwest of the cantonal capital of Zug. Surrounding Cham, Steinhausen is to the east, Hünenberg is to the west, Lake Zug is south, and Maschwanden and Knonau in the Canton of Zürich are to the north. The town has an area of . The train station is located above sea level and the highest point in town is above sea level. The town is located at the mouth of the Lorze river, with two sections (Kirchbühl and Städtli) located on both sides of the river. Cham also includes a number of smaller villages; Enikon, Lindencham, Friesencham, Hagendorn, Rumentikon, Niederwil, Oberwil and Bibersee. Cham has an area, , of . Of this area, 63.3% is used for agricultural purposes, while 13.2% is forested. Of the rest of the land, 21.7% is settled (buildings or roads) and the remainder (1.8%) is non-productive (rivers, glaciers or mountains). History The shores of Lak ...
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Japan Antibiotics Research Association
Japan ( ja, 日本, or , and formally , ''Nihonkoku'') is an island country in East Asia. It is situated in the northwest Pacific Ocean, and is bordered on the west by the Sea of Japan, while extending from the Sea of Okhotsk in the north toward the East China Sea, Philippine Sea, and Taiwan in the south. Japan is a part of the Ring of Fire, and spans an archipelago of 6852 islands covering ; the five main islands are Hokkaido, Honshu (the "mainland"), Shikoku, Kyushu, and Okinawa. Tokyo is the nation's capital and largest city, followed by Yokohama, Osaka, Nagoya, Sapporo, Fukuoka, Kobe, and Kyoto. Japan is the eleventh most populous country in the world, as well as one of the most densely populated and urbanized. About three-fourths of the country's terrain is mountainous, concentrating its population of 123.2 million on narrow coastal plains. Japan is divided into 47 administrative prefectures and eight traditional regions. The Greater Tokyo Area is the most pop ...
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Sea Squirt
Ascidiacea, commonly known as the ascidians, tunicates (in part), and sea squirts (in part), is a polyphyletic class (biology), class in the subphylum Tunicate, Tunicata of sac-like marine (ocean), marine invertebrate filter feeders. Ascidians are characterized by a tough outer "tunic" made of a polysaccharide. Ascidians are found all over the world, usually in shallow water with salinity, salinities over 2.5%. While members of the Thaliacea and Larvacea (Appendicularia) swim freely like plankton, sea squirts are Sessility (zoology), sessile animals after their larval phase: they then remain firmly attached to their Substrate (marine biology), substratum, such as rocks and shells. There are 2,300 species of ascidians and three main types: solitary ascidians, social ascidians that form clumped communities by attaching at their bases, and compound ascidians that consist of many small individuals (each individual is called a zooid) pyrosome, forming colonies up to several meters in ...
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The Journal Of Antibiotics
''The Journal of Antibiotics'' is a peer-reviewed medical journal published by the Nature Publishing Group Nature Portfolio (formerly known as Nature Publishing Group and Nature Research) is a division of the international scientific publishing company Springer Nature that publishes academic journals, magazines, online databases, and services in scien ... for the Japan Antibiotics Research Association. The journal seeks to endorse studies on antibiotics and associated types of biologically substances. In June 2020, the journal published a pioneer systematic review on Ivermectin and COVID-19 by Fatemeh Heiday and Reza Gharebaghi which later identified as highly cited in this field. References External links * Microbiology journals Nature Research academic journals Monthly journals Publications established in 1948 English-language journals Academic journals associated with learned and professional societies {{med-journal-stub ...
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