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American Society Of Pharmacognosy
The American Society of Pharmacognosy (ASP) is a scientific society that promotes the growth and development of pharmacognosy through presentation of research achievements and publication of meritorious research. ASP was founded in 1959 as an outgrowth of the Plant Science Seminar established in 1923. ASP has over 1,100 active and associate members. Approximately 40 percent of the active members reside outside the U.S. and Canada in more than 60 countries. Pharmacognosy includes the study of the physical, chemical, biochemical and biological properties of drugs, drug substances, or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources. Research problems in pharmacognosy include studies in the areas of phytochemistry, microbial chemistry, biosynthesis, biotransformation, chemotaxonomy and other biological and chemical sciences. ASP publishes the quarterly ''ASP Newsletter'' and co-publishes the ''Journal of Natural Products' ...
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Pharmacognosy
Pharmacognosy is the study of medicinal plants and other natural substances as sources of drugs. The American Society of Pharmacognosy defines pharmacognosy as "the study of the physical, chemical, biochemical, and biological properties of drugs, drug substances, or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources". Description The word "pharmacognosy" is derived from two Greek words: ', (drug), and ''gnosis'' (knowledge) or the Latin verb '' cognosco'' (', 'with', and , 'know'; itself a cognate of the Greek verb , , meaning 'I know, perceive'), meaning 'to conceptualize' or 'to recognize'. The term "pharmacognosy" was used for the first time by the Austrian physician Schmidt in 1811 and by Anotheus Seydler in 1815 in a work titled ''Analecta Pharmacognostica''. Originally—during the 19th century and the beginning of the 20th century—"pharmacognosy" was used to define the branch of medicine or commodity scie ...
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Phytochemistry
Phytochemistry is the study of phytochemicals, which are chemicals derived from plants. Phytochemists strive to describe the structures of the large number of secondary metabolites found in plants, the functions of these compounds in human and plant biology, and the biosynthesis of these compounds. Plants synthesize phytochemicals for many reasons, including to protect themselves against insect attacks and plant diseases. The compounds found in plants are of many kinds, but most can be grouped into four major biosynthetic classes: alkaloids, phenylpropanoids, polyketides, and terpenoids. Phytochemistry can be considered a subfield of botany or chemistry. Activities can be led in botanical gardens or in the wild with the aid of ethnobotany. Phytochemical studies directed toward human (i.e. drug discovery) use may fall under the discipline of pharmacognosy, whereas phytochemical studies focused on the ecological functions and evolution of phytochemicals likely fall under the disci ...
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Microbial Chemistry
A microorganism, or microbe,, ''mikros'', "small") and ''organism'' from the el, ὀργανισμός, ''organismós'', "organism"). It is usually written as a single word but is sometimes hyphenated (''micro-organism''), especially in older texts. The informal synonym ''microbe'' () comes from μικρός, mikrós, "small" and βίος, bíos, "life". is an organism of microscopic size, which may exist in its single-celled form or as a colony of cells. The possible existence of unseen microbial life was suspected from ancient times, such as in Jain scriptures from sixth century BC India. The scientific study of microorganisms began with their observation under the microscope in the 1670s by Anton van Leeuwenhoek. In the 1850s, Louis Pasteur found that microorganisms caused food spoilage, debunking the theory of spontaneous generation. In the 1880s, Robert Koch discovered that microorganisms caused the diseases tuberculosis, cholera, diphtheria, and anthrax. Because micro ...
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Biosynthesis
Biosynthesis is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms. In biosynthesis, simple compounds are modified, converted into other compounds, or joined to form macromolecules. This process often consists of metabolic pathways. Some of these biosynthetic pathways are located within a single cellular organelle, while others involve enzymes that are located within multiple cellular organelles. Examples of these biosynthetic pathways include the production of lipid membrane components and nucleotides. Biosynthesis is usually synonymous with anabolism. The prerequisite elements for biosynthesis include: precursor compounds, chemical energy (e.g. ATP), and catalytic enzymes which may require coenzymes (e.g.NADH, NADPH). These elements create monomers, the building blocks for macromolecules. Some important biological macromolecules include: proteins, which are composed of amino acid monomers joined via peptide bon ...
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Biotransformation
Biotransformation is the biochemical modification of one chemical compound or a mixture of chemical compounds. Biotransformations can be conducted with whole cells, their lysates, or purified enzymes. Increasingly, biotransformations are effected with purified enzymes. Major industries and life-saving technologies depend on biotransformations. Advantages and disadvantages Compared to the conventional production of chemicals, biotransformations are often attractive because their selectivities can be high, limiting the coproduction of undesirable coproducts. Generally operating under mild temperatures and pressures in aqueous solutions, many biotransformations are "green". The catalysts, i.e. the enzymes, are amenable to improvement by genetic manipulation. Biotechnology usually is restrained by substrate scope. Petrochemicals for example are often not amenable to biotransformations, especially on the scale required for some applications, e.g. fuels. Biotransformations can be s ...
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Chemotaxonomy
Webster's Dictionary, Merriam-Webster defines ''chemotaxonomy'' as the method of biology, biological classification based on similarities and dissimilarity in the structure of certain chemical compound, compounds among the organisms being classified. Advocates argue that, as proteins are more closely controlled by genes and less subjected to natural selection than the anatomy, anatomical features, they are more reliable indicators of genetic distance, genetic relationships. The compounds studied most are proteins, amino acids, nucleic acids, peptides etc. Physiology is the study of working of organ (anatomy), organs in a List of life forms, living being. Since working of the organs involves chemicals of the human body, body, these compounds are called biochemical, biochemical evidences. The study of Morphology (biology), morphological change has shown that there are changes in the anatomy, structure of animals which result in evolution. When changes take place in the structure of a ...
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Journal Of Natural Products
The ''Journal of Natural Products'' is a monthly peer-reviewed scientific journal covering all aspects of research on the chemistry and/or biochemistry of naturally occurring compounds. It is co-published by the American Society of Pharmacognosy and the American Chemical Society. The editor-in-chief is Philip J. Proteau (Oregon State University). History The journal was established in 1938 as ''Lloydia'', published by the Lloyd Library and Museum, and obtained its present title in 1979. It has been the official journal of the American Society of Pharmacognosy since 1961. Originally a quarterly publication, it became a bimonthly journal in 1975, and has appeared monthly since 1992. The American Society of Pharmacognosy began to co-publish the journal with the American Chemical Society in 1996. In 2008, the journal was hijacked by a low-quality open access journal using the same title. , this counterfeit journal was still active. Abstracting and indexing The journal is abstracted a ...
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American Chemical Society
The American Chemical Society (ACS) is a scientific society based in the United States that supports scientific inquiry in the field of chemistry. Founded in 1876 at New York University, the ACS currently has more than 155,000 members at all degree levels and in all fields of chemistry, chemical engineering, and related fields. It is one of the world's largest scientific societies by membership. The ACS is a 501(c) organization, 501(c)(3) non-profit organization and holds a congressional charter under Title 36 of the United States Code. Its headquarters are located in Washington, D.C., and it has a large concentration of staff in Columbus, Ohio. The ACS is a leading source of scientific information through its peer-reviewed scientific journals, national conferences, and the Chemical Abstracts Service. Its publications division produces over 60 Scientific journal, scholarly journals including the prestigious ''Journal of the American Chemical Society'', as well as the weekly tra ...
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Satoshi Ōmura
is a Japanese biochemist. He is known for the discovery and development of hundreds of pharmaceuticals originally occurring in microorganisms. In 2015, he was awarded the Nobel Prize in Physiology or Medicine jointly with William C. Campbell for their role in the discovery of avermectins and ivermectin, the world's first endectocide and a safe and highly effective microfilaricide. It is believed that the large molecular size of ivermectin prevents it from crossing the blood/aqueous humour barrier, and renders the drug an important treatment of helminthically-derived blindness. Early life and education Satoshi Ōmura was born in Nirasaki, Yamanashi Japan in 1935, the second son of Ōmura family. After graduating from the University of Yamanashi in 1958, he was appointed to science teacher at Tokyo Metropolitan Sumida Tech High School. In 1960, he became an auditor of Koji Nakanishi’s course at Tokyo University of Education, one year later, he enrolled in the Tokyo Universit ...
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Nobel Prize In Physiology Or Medicine
The Nobel Prize in Physiology or Medicine is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, according to Alfred Nobel's 1895 will, are awarded "to those who, during the preceding year, have conferred the greatest benefit to humankind". Nobel Prizes are awarded in the fields of Physics, Chemistry, Physiology or Medicine, Literature, and Peace. The Nobel Prize is presented annually on the anniversary of Alfred Nobel's death, 10 December. As of 2022, 114 Nobel Prizes in Physiology or Medicine have been awarded to 226 laureates, 214 men and 12 women. The first one was awarded in 1901 to the German physiologist, Emil von Behring, for his work on serum therapy and the development of a vaccine against diphtheria. The first woman to receive the Nobel Prize in Physiology or Medicine, Gerty Cori, received it in 1947 for her role in elucidati ...
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Streptomyces Avermitilis
''Streptomyces avermitilis'' is a species of bacteria in the genus ''Streptomyces''. This bacterium was discovered by Satoshi Ōmura in Shizuoka Prefecture, Japan. The first complete genome sequence of ''S. avermitilis'' was completed in 2003. The genome consists of a single chromosome with a linear structure, unlike most bacterial genomes, which exist in the form of circular chromosomes. Avermectins are industrially produced from ''S. avermitilis''. Avermectin itself was discovered by the Satoshi Ōmura group and first disclosed in Burg ''et al.'' 1979. One of the most widely employed drugs against nematode and arthropod infestations is the avermectin derivative ivermectin, as well as abamectin, a widely used insecticide and antihelmintic. See also * List of Streptomyces species, List of ''Streptomyces'' species References External links *Type strain of ''Streptomyces avermitilis'' at Bac''Dive'' - the Bacterial Diversity Metadatabase
Streptomyces, avermitilis ...
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Jerry L
Jerry may refer to: Animals * Jerry (Grand National winner), racehorse, winner of the 1840 Grand National * Jerry (St Leger winner), racehorse, winner of 1824 St Leger Stakes Arts, entertainment, and media * ''Jerry'' (film), a 2006 Indian film * "Jerry", a song from the album ''Young and Free'' by Rock Goddess * Tom and Jerry (other) People * Jerry (given name), including a list of people and fictional characters with the name * Harold A. Jerry, Jr. (1920–2001), New York politician * Thomas Jeremiah (d. 1775), commonly known simply as "Jerry", a free Negro in colonial South Carolina Places * Branche à Jerry, a tributary of the Baker River in Quebec and New Brunswick, Canada * Jerry, Washington, a community in the United States Other uses * Jerry (company) * Jerry (WWII), Allied nickname for Germans, originally from WWI but widely used in World War II * Jerry Rescue (1851), involving American slave William Henry, who called himself "Jerry" See also * Geri ( ...
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