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Streptomyces Avermitilis
''Streptomyces avermitilis'' is a species of bacteria in the genus ''Streptomyces''. This bacterium was discovered by Satoshi Ōmura in Shizuoka Prefecture, Japan. The first complete genome sequence of ''S. avermitilis'' was completed in 2003. The genome consists of a single chromosome with a linear structure, unlike most bacterial genomes, which exist in the form of circular chromosomes. Avermectins are industrially produced from ''S. avermitilis''. Avermectin itself was discovered by the Satoshi Ōmura group and first disclosed in Burg ''et al.'' 1979. One of the most widely employed drugs against nematode and arthropod infestations is the avermectin derivative ivermectin, as well as abamectin, a widely used insecticide and antihelmintic. See also * List of Streptomyces species, List of ''Streptomyces'' species References External links *Type strain of ''Streptomyces avermitilis'' at Bac''Dive'' - the Bacterial Diversity Metadatabase Streptomyces, avermitilis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Richard W
Richard is a male given name. It originates, via Old French, from Old Frankish and is a compound of the words descending from Proto-Germanic ''*rīk-'' 'ruler, leader, king' and ''*hardu-'' 'strong, brave, hardy', and it therefore means 'strong in rule'. Nicknames include "Richie", "Dick", "Dickon", " Dickie", "Rich", "Rick", "Rico", "Ricky", and more. Richard is a common English, German and French male name. It's also used in many more languages, particularly Germanic, such as Norwegian, Danish, Swedish, Icelandic, and Dutch, as well as other languages including Irish, Scottish, Welsh and Finnish. Richard is cognate with variants of the name in other European languages, such as the Swedish "Rickard", the Catalan "Ricard" and the Italian "Riccardo", among others (see comprehensive variant list below). People named Richard Multiple people with the same name * Richard Andersen (other) * Richard Anderson (other) * Richard Cartwright (other) * Ri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Seung Bum Kim
The ''sueng'' ( th, ซึง, Burmese: ၄ကြိုးထပ်ပို (ဆီုင်), , also spelled ''seung'' or ''süng'') is a plucked fretted lute from the northern (Lanna) region of Thailand. The instrument is made from hardwood and its strings (numbering either four or six and arranged in courses of two) are most often made of steel wire. It has nine bamboo frets. The ''sueng'' is part of a northern Thai traditional ensemble called the ''salo''-''so (saw)''-''sueng'' ensemble, along with the ''salo'' (3-string spike fiddle) and ''pi so'' (free reed pipe). The ''sueng'' is similar to the ''grajabpi'' (กระจับปี่), an ancient Thai instrument that is used in the classical music of central Thailand. Construction Most suengs are made from a single piece of Jackfruit wood, carved into shape by the artisan. Once carved, a round sound board of the same wood is glued to the instrument. Trapezoid shaped sticks are cut form a bamboo stem and installed ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Michael Goodfellow
Michael Goodfellow OBE (born 8 January 1941) is a British professor in microbial systematics, specialising in Actinomycetota taxonomy. He earlier served as head of the School of Biology in University of Newcastle upon Tyne. He is also the chair of the Bergey's Manual Trust. Education Goodfellow was born in Ecclefechan, Scotland and went to school at Carlisle Grammar School. He did both his undergraduate and postgraduate degrees at the University of Liverpool, graduating with PhD in 1966. He took a postdoctoral fellowship at Penn State, then as an MRC Junior Research Fellow at the University of Leicester. In 1969 he joined the then newly established University of Newcastle, where he currently serves as head of the School of Biology.Homepage of Prof Michael Goodfellow at University of New ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yōko Takahashi
is a Japanese singer, who is best known for her work throughout the 1990s, most particularly for her singles which were performed for and featured in anime, most notably the ''Neon Genesis Evangelion'' franchise. Career Takahashi began her career in 1991, and released her first album, ''Pizzicato'', in 1992, which reached #28 on the Oricon weekly charts. In the following years, she released the albums ''Kugatsu no Sotsugyō'' which charted, and '' Watashi wo Mitsukete'', which did not achieve the same success of her previous albums. In 1995, she released the single , which was used as the opening song in the anime series ''Neon Genesis Evangelion''. The song has received gold and platinum certifications, charted on the Oricon weekly chart numerous times, and has frequently been cited as one of the most influential songs used in anime. She has remixed and released several versions of the single, which have been met with the same commercial success. In 1996, she released ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Streptomyces
''Streptomyces'' is the largest genus of Actinomycetota and the type genus of the family Streptomycetaceae. Over 500 species of ''Streptomyces'' bacteria have been described. As with the other Actinomycetota, streptomycetes are gram-positive, and have genomes with high GC content. Found predominantly in soil and decaying vegetation, most streptomycetes produce spores, and are noted for their distinct "earthy" odor that results from production of a volatile metabolite, geosmin. Streptomycetes are characterised by a complex secondary metabolism. They produce over two-thirds of the clinically useful antibiotics of natural origin (e.g., neomycin, streptomycin, cypemycin, grisemycin, bottromycins and chloramphenicol). The antibiotic streptomycin takes its name directly from ''Streptomyces''. Streptomycetes are infrequent pathogens, though infections in humans, such as mycetoma, can be caused by '' S. somaliensis'' and '' S. sudanensis'', and in plants can be caused by '' S. cavi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Satoshi Ōmura
is a Japanese biochemist. He is known for the discovery and development of hundreds of pharmaceuticals originally occurring in microorganisms. In 2015, he was awarded the Nobel Prize in Physiology or Medicine jointly with William C. Campbell for their role in the discovery of avermectins and ivermectin, the world's first endectocide and a safe and highly effective microfilaricide. It is believed that the large molecular size of ivermectin prevents it from crossing the blood/aqueous humour barrier, and renders the drug an important treatment of helminthically-derived blindness. Early life and education Satoshi Ōmura was born in Nirasaki, Yamanashi Japan in 1935, the second son of Ōmura family. After graduating from the University of Yamanashi in 1958, he was appointed to science teacher at Tokyo Metropolitan Sumida Tech High School. In 1960, he became an auditor of Koji Nakanishi’s course at Tokyo University of Education, one year later, he enrolled in the Tokyo Universit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Shizuoka Prefecture
is a prefecture of Japan located in the Chūbu region of Honshu. Shizuoka Prefecture has a population of 3,637,998 and has a geographic area of . Shizuoka Prefecture borders Kanagawa Prefecture to the east, Yamanashi Prefecture to the northeast, Nagano Prefecture to the north, and Aichi Prefecture to the west. Shizuoka is the capital and Hamamatsu is the largest city in Shizuoka Prefecture, with other major cities including Fuji, Numazu, and Iwata. Shizuoka Prefecture is located on Japan's Pacific Ocean coast and features Suruga Bay formed by the Izu Peninsula, and Lake Hamana which is considered to be one of Japan's largest lakes. Mount Fuji, the tallest volcano in Japan and cultural icon of the country, is partially located in Shizuoka Prefecture on the border with Yamanashi Prefecture. Shizuoka Prefecture has a significant motoring heritage as the founding location of Honda, Suzuki, and Yamaha, and is home to the Fuji International Speedway. History Shizuoka Prefe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Japan
Japan ( ja, 日本, or , and formally , ''Nihonkoku'') is an island country in East Asia. It is situated in the northwest Pacific Ocean, and is bordered on the west by the Sea of Japan, while extending from the Sea of Okhotsk in the north toward the East China Sea, Philippine Sea, and Taiwan in the south. Japan is a part of the Ring of Fire, and spans Japanese archipelago, an archipelago of List of islands of Japan, 6852 islands covering ; the five main islands are Hokkaido, Honshu (the "mainland"), Shikoku, Kyushu, and Okinawa Island, Okinawa. Tokyo is the Capital of Japan, nation's capital and largest city, followed by Yokohama, Osaka, Nagoya, Sapporo, Fukuoka, Kobe, and Kyoto. Japan is the List of countries and dependencies by population, eleventh most populous country in the world, as well as one of the List of countries and dependencies by population density, most densely populated and Urbanization by country, urbanized. About three-fourths of Geography of Japan, the c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chromosome
A chromosome is a long DNA molecule with part or all of the genetic material of an organism. In most chromosomes the very long thin DNA fibers are coated with packaging proteins; in eukaryotic cells the most important of these proteins are the histones. These proteins, aided by chaperone proteins, bind to and condense the DNA molecule to maintain its integrity. These chromosomes display a complex three-dimensional structure, which plays a significant role in transcriptional regulation. Chromosomes are normally visible under a light microscope only during the metaphase of cell division (where all chromosomes are aligned in the center of the cell in their condensed form). Before this happens, each chromosome is duplicated ( S phase), and both copies are joined by a centromere, resulting either in an X-shaped structure (pictured above), if the centromere is located equatorially, or a two-arm structure, if the centromere is located distally. The joined copies are now called si ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Avermectin
The avermectins are a series of drugs and pesticides used to treat parasitic worms and insect pests. They are a group of 16-membered macrocyclic lactone derivatives with potent anthelmintic and insecticidal properties. These naturally occurring compounds are generated as fermentation products by ''Streptomyces avermitilis'', a soil actinomycete. Eight different avermectins were isolated in four pairs of homologue compounds, with a major (a-component) and minor (b-component) component usually in ratios of 80:20 to 90:10. Other anthelmintics derived from the avermectins include ivermectin, selamectin, doramectin, eprinomectin, and abamectin. Half of the 2015 Nobel Prize in Physiology or Medicine was awarded to William C. Campbell and Satoshi Ōmura for discovering avermectin, "the derivatives of which have radically lowered the incidence of river blindness and lymphatic filariasis, as well as showing efficacy against an expanding number of other parasitic diseases." History I ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Journal Of Antibiotics
''The Journal of Antibiotics'' is a peer-reviewed medical journal published by the Nature Publishing Group Nature Portfolio (formerly known as Nature Publishing Group and Nature Research) is a division of the international scientific publishing company Springer Nature that publishes academic journals, magazines, online databases, and services in scien ... for the Japan Antibiotics Research Association. The journal seeks to endorse studies on antibiotics and associated types of biologically substances. In June 2020, the journal published a pioneer systematic review on Ivermectin and COVID-19 by Fatemeh Heiday and Reza Gharebaghi which later identified as highly cited in this field. References External links * Microbiology journals Nature Research academic journals Monthly journals Publications established in 1948 English-language journals Academic journals associated with learned and professional societies {{med-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Japan Antibiotics Research Association
Japan ( ja, 日本, or , and formally , ''Nihonkoku'') is an island country in East Asia. It is situated in the northwest Pacific Ocean, and is bordered on the west by the Sea of Japan, while extending from the Sea of Okhotsk in the north toward the East China Sea, Philippine Sea, and Taiwan in the south. Japan is a part of the Ring of Fire, and spans an archipelago of 6852 islands covering ; the five main islands are Hokkaido, Honshu (the "mainland"), Shikoku, Kyushu, and Okinawa. Tokyo is the nation's capital and largest city, followed by Yokohama, Osaka, Nagoya, Sapporo, Fukuoka, Kobe, and Kyoto. Japan is the eleventh most populous country in the world, as well as one of the most densely populated and urbanized. About three-fourths of the country's terrain is mountainous, concentrating its population of 123.2 million on narrow coastal plains. Japan is divided into 47 administrative prefectures and eight traditional regions. The Greater Tokyo Area is the most pop ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
