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Abdala (vaccine)
Abdala, technical name CIGB-66, is a COVID-19 vaccine developed by the Center for Genetic Engineering and Biotechnology in Cuba. This candidate, named after a patriotic drama by Cuban independence hero José Martí, is a protein subunit vaccine containing COVID-derived proteins that trigger an immune response. The full results of the clinical trial have not yet been published. This candidate followed a previous one called CIGB-669 (MAMBISA). The vaccine is one of two Cuba-developed COVID-19 vaccines which has passed Phase III trials, and has received emergency authorisation. Medical uses The vaccine was administered in 3 doses spaced 2 weeks apart. Efficacy On 22 June 2021, The official Cuban government sources reported that the results of an initial study by the Cuban Center for Genetic Engineering and Biotechnology involving 48,290 participants found a 92.28% efficacy rate at preventing symptomatic COVID-19. The report included a confidence interval of without a sp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Severe Acute Respiratory Syndrome Coronavirus 2
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic. The virus previously had a Novel coronavirus, provisional name, 2019 novel coronavirus (2019-nCoV), and has also been called the human coronavirus 2019 (HCoV-19 or hCoV-19). First identified in the city of Wuhan, Hubei, China, the World Health Organization declared the outbreak a public health emergency of international concern on January 30, 2020, and a pandemic on March 11, 2020. SARS‑CoV‑2 is a positive-sense single-stranded RNA virus that is Contagious disease, contagious in humans. SARS‑CoV‑2 is a virus of the species ''severe acute respiratory syndrome–related coronavirus'' (SARSr-CoV), related to the Severe acute respiratory syndrome coronavirus 1, SARS-CoV-1 virus that caused the 2002–2004 SARS outbreak. Despite its close relation to SARS-CoV-1, i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Preprint
In academic publishing, a preprint is a version of a scholarly or scientific paper that precedes formal peer review and publication in a peer-reviewed scholarly or scientific journal. The preprint may be available, often as a non-typeset version available free, before or after a paper is published in a journal. History Since 1991, preprints have increasingly been distributed electronically on the Internet, rather than as paper copies. This has given rise to massive preprint databases such as arXiv and HAL (open archive) etc. to institutional repositories. The sharing of preprints goes back to at least the 1960s, when the National Institutes of Health circulated biological preprints. After six years the use of these Information Exchange Groups was stopped, partially because journals stopped accepting submissions shared via these channels. In 2017, the Medical Research Council started supporting citations of preprints in grant and fellowship applications, and Wellcome Trust star ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cuban COVID-19 Vaccines
Cuban may refer to: * Something of, from, or related to Cuba, a country in the Caribbean * Cubans, people from Cuba, or of Cuban descent ** Cuban exile, a person who left Cuba for political reasons, or a descendant thereof * Cuban citizen, a person who is part of the Cuban population, see Demographics of Cuba * Cuban Spanish, the dialect of Cuba * Cuban Americans, citizens of the United States who are of Cuban descent * Cuban cigar, often referred to as "Cubans" * Cuban culture * Cuban cuisine ** Cuban sandwich * Cuban-eight, a type of aerobatic maneuver People with the surname * Brian Cuban (born 1961), American lawyer and activist * Mark Cuban (born 1958), American entrepreneur See also * Cuban Missile Crisis * List of Cubans * * Cuban Boys, a British music act * Kuban (other) * Cubane Cubane () is a synthetic hydrocarbon compound that consists of eight carbon atoms arranged at the corners of a cube, with one hydrogen atom attached to each carbon atom. A solid cryst ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Trials
Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on dosage, safety and efficacy. They are conducted only after they have received health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial—their approval does not mean the therapy is 'safe' or effective, only that the trial may be conducted. Depending on product type and development stage, investigators initially enroll volunteers or patients into small pilot studies, and subsequently conduct progressively larger scale comparative studies. Clinical trials can vary i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Delcy Rodríguez
Delcy Eloína Rodríguez Gómez (born 18 May 1969) is a Venezuelan politician serving as the vice president of Venezuela since 2018. She was also Minister of Popular Power for Communication and Information of Venezuela from 2013 to 2014, Minister of Foreign Affairs from 2014 to 2017 and President of the Constituent Assembly of Venezuela from 4 August 2017 to 14 June 2018. She is the target of multiple international sanctions. Political career She held several posts during the course of the Chavez administration: as International Affairs Director in the Ministry of Energy and Mines, in 2003; as Vice-minister for European Affairs in 2005; serving from February–August 2006 as the Minister for Presidential Affairs and the following year as General Coordinator to the Vice-President of Venezuela, both of which roles she held while her brother occupied the office of Vice President of the Republic. She was the Minister for Presidential Affairs in 2006. Similarly, she was Vice Min ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vice President Of Venezuela
The vice president of Venezuela ( es, Vicepresidente de Venezuela), officially known as the Executive Vice President of the Bolivarian Republic of Venezuela ( es, Vicepresidente Ejecutivo de la República Bolivariana de Venezuela), is the second highest political position in the government of Venezuela. The vice president is the direct collaborator of the Venezuelan president according to the Constitution. The office of vice president appeared in the Constitution of 1830 until the Constitution of 1858, and once again in the Constitution of 1999. However, in its current (1999) incarnation, the office is more akin to a prime minister in systems as those of France and South Korea. Since June 14, 2018, Delcy Rodríguez of the United Socialist Party of Venezuela has been vice president, serving with President Nicolás Maduro. Office of the executive vice president Functions and duties According to the Constitution of 1999, the duties of the executive vice president are # To collabor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SOBERANA 02
Soberana 02 or Soberana 2, technical name FINLAY-FR-2, is a COVID-19 vaccine produced by the Finlay Institute, a Cuban epidemiological research institute. The vaccine is known as PastoCovac ( fa, پاستوکووک) in Iran, where it has been developed in collaboration with the Pasteur Institute of Iran. It is a conjugate vaccine that requires two doses, the second one being administered 28 days after the first shot. A third (booster) dose of Soberana Plus may also be given on day 56. It has received emergency use authorization in Iran on June 2021, and in Cuba on August 2021, where it has also been approved for children above 2 years old. The name of the vaccine, Soberana, is a Spanish word that means "sovereign". It followed a previous candidate vaccine called SOBERANA-01 (FINLAY-FR-1). Medical uses The vaccine requires two doses, the second one being administered four weeks after the first shot. A third (boost) dose of Soberana Plus may also be given on eight weeks. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Placebo
A placebo ( ) is a substance or treatment which is designed to have no therapeutic value. Common placebos include inert tablets (like sugar pills), inert injections (like Saline (medicine), saline), sham surgery, and other procedures. In general, placebos can affect how patients perceive their condition and encourage the body's chemical processes for relieving pain and a few other symptoms, but have no impact on the disease itself. Improvements that patients experience after being treated with a placebo can also be due to unrelated factors, such as regression to the mean (a statistical effect where an unusually high or low measurement is likely to be followed by a less extreme one). The use of placebos in clinical medicine raises ethical concerns, especially if they are disguised as an active treatment, as this introduces dishonesty into the doctor–patient relationship and bypasses informed consent. While it was once assumed that this deception was necessary for placebos to have ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ministry Of Health (Vietnam)
The Ministry of Health (MOH, vi, Bộ Y tế) is the government ministry responsible for the governance and guidance of the health, healthcare and health care industry, health industry of Vietnam. In conjunction with other ministries and the prime minister's office, the Ministry is responsible for creating and promulgating long-term health policy programs such as the "National Strategy on Nutrition for the 2001 - 2010 period" and the "National Policy on Injury Prevention 2002 - 2010". Its main offices are located in Ba Đình District, Hanoi. In November 2019, Minister Nguyễn Thị Kim Tiến was dismissed from the position because she reached retirement age and Deputy Prime Minister Vũ Đức Đam took charge of the ministry. On 7 July 2020, amidst the COVID-19 pandemic, Nguyễn Thanh Long, who is a professor specialized in infectious diseases, was temporarily appointed for the position, acting as the Minister of Health. On 12 November 2020, he officially became the Ministe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aljazeera
Al Jazeera ( ar, الجزيرة, translit-std=DIN, translit=al-jazīrah, , "The Island") is a state-owned Arabic-language international radio and TV broadcaster of Qatar. It is based in Doha and operated by the media conglomerate Al Jazeera Media Network. The flagship of the network, its station identification, is ''Al Jazeera.'' The patent holding is a " private foundation for public benefit" under Qatari law. Under this organizational structure, the parent receives funding from the government of Qatar but maintains its editorial independence. In June 2017, the Saudi, Emirati, Bahraini, and Egyptian governments insisted on the closure of the entire conglomerate as one of thirteen demands made to the Government of Qatar during the Qatar diplomatic crisis. The channel has been criticised by some organisations as well as nations such as Saudi Arabia for being "Qatari propaganda". Etymology In Arabic, ' literally means "the island". However, it refers here to the Arabian Pe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nicolás Maduro
Nicolás Maduro Moros (; born 23 November 1962) is a Venezuelan politician and president of Venezuela since 2013, with his presidency under dispute since 2019. Beginning his working life as a bus driver, Maduro rose to become a trade union leader before being elected to the National Assembly in 2000. He was appointed to a number of positions under President Hugo Chávez, serving as President of the National Assembly from 2005 to 2006, as Minister of Foreign Affairs from 2006 to 2013 and as the vice president from 2012 to 2013 under Chávez. After Chávez's death was announced on 5 March 2013, Maduro assumed the presidency. A special presidential election was held in 2013, which Maduro won with 50.62% of the vote as the United Socialist Party of Venezuela candidate. He has ruled Venezuela by decree since 2015 through powers granted to him by the ruling party legislature. Shortages in Venezuela and decreased living standards led to protests beginning in 2014 that escala ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polyhistidine-tag
A polyhistidine-tag is an amino acid motif in proteins that typically consists of at least six histidine (''His'') residues, often at the N- or C-terminus of the protein. It is also known as hexa histidine-tag, 6xHis-tag, His6 tag, by the US trademarked name HIS TAG (US Trademark serial number 74242707), and most commonly as His-Tag. The tag was invented by Roche, although the use of histidines and its vectors are distributed by Qiagen. Various purification kits for histidine-tagged proteins are available from Qiagen, Sigma-Aldrich Corporation, Sigma, Thermo Scientific, GE Healthcare, Macherey-NagelCube Biotech Clontech, Bio-Radand others. MK(HQ)6 may be used for enhanced expression in ''E. coli'' and tag removal. The total number of histidine residues may vary in the tag from as low as two, to as high as 10 or more His residues. N- or C-terminal His-tags may also be followed or preceded, respectively, by a suitable amino acid sequence that facilitates removal of the polyhistidine ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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