SOBERANA 02
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SOBERANA 02
Soberana 02 or Soberana 2, technical name FINLAY-FR-2, is a COVID-19 vaccine produced by the Finlay Institute, a Cuban epidemiological research institute. The vaccine is known as PastoCovac ( fa, پاستوکووک) in Iran, where it has been developed in collaboration with the Pasteur Institute of Iran. It is a conjugate vaccine that requires two doses, the second one being administered 28 days after the first shot. A third (booster) dose of Soberana Plus may also be given on day 56. It has received emergency use authorization in Iran on June 2021, and in Cuba on August 2021, where it has also been approved for children above 2 years old. The name of the vaccine, Soberana, is a Spanish word that means "sovereign". It followed a previous candidate vaccine called SOBERANA-01 (FINLAY-FR-1). Medical uses The vaccine requires two doses, the second one being administered four weeks after the first shot. A third (boost) dose of Soberana Plus may also be given on eight weeks. ...
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Severe Acute Respiratory Syndrome Coronavirus 2
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic. The virus previously had a Novel coronavirus, provisional name, 2019 novel coronavirus (2019-nCoV), and has also been called the human coronavirus 2019 (HCoV-19 or hCoV-19). First identified in the city of Wuhan, Hubei, China, the World Health Organization declared the outbreak a public health emergency of international concern on January 30, 2020, and a pandemic on March 11, 2020. SARS‑CoV‑2 is a positive-sense single-stranded RNA virus that is Contagious disease, contagious in humans. SARS‑CoV‑2 is a virus of the species ''severe acute respiratory syndrome–related coronavirus'' (SARSr-CoV), related to the Severe acute respiratory syndrome coronavirus 1, SARS-CoV-1 virus that caused the 2002–2004 SARS outbreak. Despite its close relation to SARS-CoV-1, i ...
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Chinese Hamster Ovary Cell
Chinese hamster ovary (CHO) cells are an epithelial cell line derived from the ovary of the Chinese hamster, often used in biological and medical research and commercially in the production of recombinant therapeutic proteins. They have found wide use in studies of genetics, toxicity screening, nutrition and gene expression, particularly to express recombinant proteins. CHO cells are the most commonly used mammalian hosts for industrial production of recombinant protein therapeutics. History Chinese hamsters had been used in research since 1919, where they were used in place of mice for typing pneumococci. They were subsequently found to be excellent vectors for transmission of kala-azar (visceral leishmaniasis), facilitating '' Leishmania'' research. In 1948, the Chinese hamster was first used in the United States for breeding in research laboratories. In 1957, Theodore T. Puck obtained a female Chinese hamster from Dr. George Yerganian's laboratory at the Boston Cancer R ...
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COVID-19 Vaccine Clinical Research
COVID-19 vaccine clinical research uses clinical research to establish the characteristics of COVID-19 COVID-19 vaccine, vaccines. These characteristics include #Efficacy, efficacy, #Effectiveness, effectiveness and safety. , 40 vaccines are authorized by at least one national regulation of therapeutic goods, regulatory authority for public use: * one DNA vaccine: ZyCoV-D * four RNA vaccines: Pfizer–BioNTech COVID-19 vaccine, Pfizer–BioNTech, Moderna COVID-19 vaccine, Moderna, Walvax COVID-19 vaccine, Walvax, and HGC019, Gemcovac * twelve inactivated vaccines: Chinese Academy of Medical Sciences COVID-19 vaccine, Chinese Academy of Medical Sciences, CoronaVac, Covaxin, CoviVac (Russia COVID-19 vaccine), CoviVac, COVIran Barekat, FAKHRAVAC, Minhai COVID-19 vaccine, Minhai-Kangtai, QazCovid-in, QazVac, Sinopharm Sinopharm BIBP COVID-19 vaccine, BIBP, Sinopharm WIBP COVID-19 vaccine, WIBP, Turkovac, and Valneva COVID-19 vaccine, VLA2001. * six viral vector vaccines: Sputnik Li ...
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Vaccine Adverse Event
A vaccine adverse event (VAE), sometimes referred to as a vaccine injury, is an adverse event caused by vaccination. The World Health Organization (WHO) knows VAEs as Adverse Events Following Immunization (AEFI). AEFIs can be related to the vaccine itself (product or quality defects), to the vaccination process (administration error or stress related reactions) or can occur independently from vaccination (coincidental). Most vaccine adverse events are mild. Serious injuries and deaths caused by vaccines are very rare, and the idea that severe events are common has been classed as a "common misconception about immunization" by the WHO. Some claimed vaccine injuries are not, in fact, caused by vaccines; for example, there is a subculture of advocates who attribute their children's autism to vaccine injury, despite the fact that vaccines do not cause autism. Claims of vaccine injuries appeared in litigation in the United States in the latter part of the 20th century. Some families ...
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Santiago De Cuba
Santiago de Cuba is the second-largest city in Cuba and the capital city of Santiago de Cuba Province. It lies in the southeastern area of the island, some southeast of the Cuban capital of Havana. The municipality extends over , and contains the communities of Antonio Maceo, Bravo, Castillo Duany, Daiquirí, El Caney, El Cobre, El Cristo, Guilera, Leyte Vidal, Moncada and Siboney. Historically Santiago de Cuba was the second-most important city on the island after Havana, and remains the second-largest. It is on a bay connected to the Caribbean Sea and an important sea port. In the 2012 population census, the city of Santiago de Cuba recorded a population of 431,272 people. History Santiago de Cuba was the fifth village founded by Spanish conquistador Diego Velázquez de Cuéllar on July 25, 1515. The settlement was destroyed by fire in 1516, and was immediately rebuilt. This was the starting point of the expeditions led by Juan de Grijalba and Hernán Cortés to the ...
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Havana
Havana (; Spanish: ''La Habana'' ) is the capital and largest city of Cuba. The heart of the La Habana Province, Havana is the country's main port and commercial center.Cuba
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The city has a population of 2.3million inhabitants, and it spans a total of – making it the largest city by area, the most populous city, and the
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