This is a list of
positron emission tomography (PET)
radiotracers
A radioactive tracer, radiotracer, or radioactive label is a chemical compound in which one or more atoms have been replaced by a radionuclide so by virtue of its radioactive decay it can be used to explore the mechanism of chemical reactions by tr ...
. These are
chemical compounds
A chemical compound is a chemical substance composed of many identical molecules (or molecular entities) containing atoms from more than one chemical element held together by chemical bonds. A molecule consisting of atoms of only one element ...
in which one or more atoms have been replaced by a short-lived,
positron emitting radioisotope.
Cardiology
*
15O.html"_;"title="Oxygen-15.html"_;"title="/nowiki>Oxygen-15">15O">Oxygen-15.html"_;"title="/nowiki>Oxygen-15">15Owater
*[Nitrogen-13.html" ;"title="Oxygen-15">15O.html" ;"title="Oxygen-15.html" ;"title="/nowiki>Oxygen-15">15O">Oxygen-15.html" ;"title="/nowiki>Oxygen-15">15Owater
*[Nitrogen-13">13N] ammonia
*[Rubidium-82, 82Rb] Rubidium-82 chloride
*[Carbon-11, 11C] Acetate (Also used in oncology)
Neurology
* sup>11C 25B-NBOMe (Cimbi-36)
* sup>18FAltanserin
Altanserin is a compound that Binding (molecular), binds to the 5-HT2A receptor, 5-HT2A receptor (5-Hydroxytryptamine (serotonin) 2A receptor). Labeled with the isotope fluorine-18 it is used as a radioligand in positron emission tomography (PET) ...
* sup>11CCarfentanil
Carfentanil or carfentanyl, sold under the brand name Wildnil, is a very potent opioid analgesic which is used in veterinary medicine to anesthetize large animals such as elephants and rhinoceroses. It is typically administered in this context ...
* sup>11CDASB
DASB, also known as 3-amino-4-(2-dimethylaminomethylphenylsulfanyl)-benzonitrile, is a compound that binds to the serotonin transporter.
Labeled with carbon-11 — a radioactive isotope — it has been used as a radioligand in neuroimagin ...
* sup>11C DTBZ or sup>18Fluoropropyl-DTBZ
* sup>11C sup>11CME@HAPTHI
* sup>18F Fallypride
* sup>18F Florbetaben
* sup>18F Flubatine
* sup>18F Fluspidine
* sup>18F Florbetapir
* sup>18For sup>11CFlumazenil
Flumazenil (also known as flumazepil, code name Ro 15-1788) is a selective GABAA receptor antagonist administered via injection, otic insertion, or intranasally. Therapeutically, it acts as both an antagonist and antidote to benzodiazepines ( ...
* sup>18F Flutemetamol
* sup>18F Fluorodopa
* sup>18F Desmethoxyfallypride
* sup>18F Mefway
* sup>18F MPPF
* sup>18F Nifene
* sup>11CPittsburgh compound B
Pittsburgh compound B (PiB) is a radioactive analog of thioflavin T, which can be used in positron emission tomography scans to image beta-amyloid plaques in neuronal tissue. Due to this property, Pittsburgh compound B may be used in investiga ...
* sup>11C Raclopride
* sup>18FSetoperone
Setoperone is a compound that is a ligand to the 5-HT2A receptor.
It can be radiolabeled with the radioisotope fluorine-18 and used as a radioligand with positron emission tomography (PET).
Several research studies have used the radiolabeled seto ...
* sup>18For sup>11C N-Methylspiperone
* sup>11CVerapamil
Verapamil, sold under various trade names, is a calcium channel blocker medication used for the treatment of high blood pressure, angina (chest pain from not enough blood flow to the heart), and supraventricular tachycardia. It may also be ...
NIMH maintains a list of CNS radiotracers that may be useful for additional information.
Neuroepigenetics
* sup>11C Martinostat[
*]
Oncology
* sup>18FFludeoxyglucose (18F)
18F.html" ;"title="sup>18F">sup>18Fluorodeoxyglucose (INN), or fluorodeoxyglucose F 18 (USAN and USP), also commonly called fluorodeoxyglucose and abbreviated 18F.html" ;"title="sup>18F">sup>18FDG, 2- 18F.html" ;"title="sup>18F">sup>18FDG or F ...
(FDG)-glucose
Glucose is a simple sugar with the molecular formula . Glucose is overall the most abundant monosaccharide, a subcategory of carbohydrates. Glucose is mainly made by plants and most algae during photosynthesis from water and carbon dioxide, u ...
analogue
* sup>11C Acetate
* sup>11C Methionine
* sup>11Ccholine Choline is an essential nutrient for humans and many other animals. Choline occurs as a cation that forms various salts (X− in the depicted formula is an undefined counteranion). Humans are capable of some ''de novo synthesis'' of choline but r ...
[FDA approves new diagnostic imaging agent to detect recurrent prostate cance]
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* sup>18F Fluorocholine
* sup>18FFET
The field-effect transistor (FET) is a type of transistor that uses an electric field to control the flow of current in a semiconductor. FETs (JFETs or MOSFETs) are devices with three terminals: ''source'', ''gate'', and ''drain''. FETs contr ...
* sup>18F FMISO
* sup>18F Fluorothymidine F-18
* sup>64Cu Cu-ETS2
* sup>64Cu Copper-64 DOTA-TATE
* sup>68GaDOTA-pseudopeptides
* sup>68GaDOTA-TATE
DOTA-TATE (DOTATATE, DOTA-octreotate, oxodotreotide, DOTA-(Tyr3)-octreotate, and DOTA-0-Tyr3-Octreotate) is an eight amino acid long peptide, with a covalently bonded DOTA bifunctional chelator.
DOTA-TATE can be reacted with the radionuclides ...
* sup>68Ga PSMA
* sup>68GaCXCR4; solid and hematologic cancers
Infectious diseases
* sup>18F Fluorodeoxysorbitol (FDS)
Further readingCNS Radiotracers that have been advanced for use in Human Studies
References
{{Diagnostic radiopharmaceuticals
Neuroimaging
PET radiotracers