Punicalin is an ellagitannin. It can be found in ''

Punica granatum The pomegranate (''Punica granatum'') is a fruit-bearing deciduous shrub in the family Lythraceae, subfamily Punicoideae, that grows between tall. The pomegranate was originally described throughout the Mediterranean region. It was introduc ...

'' (pomegranate) or in the leaves of ''

Terminalia catappa ''Terminalia catappa'' is a large tropical tree in the leadwood tree family, Combretaceae, native to Asia, Australia, the Pacific, Madagascar and Seychelles. Common names in English include country almond, Indian almond, Malabar almond, sea almon ...

'', a plant used to treat

dermatitis Dermatitis is inflammation of the skin, typically characterized by itchiness, redness and a rash. In cases of short duration, there may be small blisters, while in long-term cases the skin may become thickened. The area of skin involved can v ...

and

hepatitis Hepatitis is inflammation of the liver tissue. Some people or animals with hepatitis have no symptoms, whereas others develop yellow discoloration of the skin and whites of the eyes (jaundice), poor appetite, vomiting, tiredness, abdominal pa ...

. It is also reported in ''

Combretum glutinosum ''Combretum glutinosum'' is a shrub species of the genus ''Combretum'', found in the Sahel belt in parts of Senegal, Burkina Faso, Ghana, Mali, the Gambia, Niger, Nigeria and Cameroon, across to parts of Sudan. It is known as dooki in Pulaar, Ka ...

'', all three species being Myrtales, the two last being

Combretaceae The Combretaceae, often called the white mangrove family, are a family of flowering plants in the order Myrtales. The family includes about 530 species of trees, shrubs, and lianas in ca 10 genera. The family includes the leadwood tree, ''Combre ...

. It is a highly active

carbonic anhydrase inhibitor Carbonic anhydrase inhibitors are a class of pharmaceuticals that suppress the activity of carbonic anhydrase. Their clinical use has been established as anti-glaucoma agents, diuretics, antiepileptics, in the management of mountain sickness, ...

Chemistry

The molecule contains a

gallagic acid Gallagic acid is a polyphenolic chemical compound that can be found in the ellagitannins, a type of tannin, found in ''Punica granatum'' (pomegranate).Antioxidant, antimalarial and antimicrobial activities of tannin-rich fractions, ellagitannins an ...

component linked to a

glucose Glucose is a simple sugar with the molecular formula . Glucose is overall the most abundant monosaccharide, a subcategory of carbohydrates. Glucose is mainly made by plants and most algae during photosynthesis from water and carbon dioxide, using ...

References

Pomegranate ellagitannins Carbonic anhydrase inhibitors {{aromatic-stub