Combretum Glutinosum
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Combretum Glutinosum
''Combretum glutinosum'' is a shrub species of the genus ''Combretum'', found in the Sahel belt in parts of Senegal, Burkina Faso, Ghana, Mali, the Gambia, Niger, Nigeria and Cameroon, across to parts of Sudan. It is known as dooki in Pulaar, Kantakara in Hausa, rat in Wolof and jambakatan kè in Maninka. Its synonyms are ''Combretum cordofanum'' Engl. & Diels, ''C. passargei'' Engl. & Diels, ''C. leonense'' Engl. & Diels. Habitat ''Combretum glutinosum'' tends to grow in savanna type forests, in several soil types but is best suited to sandy and free draining soils. It is drought resistant and grows in areas of annual rainfall of . Its growth is fast and profuse. Plant growth As a bushy shrub the plant grows up to with an open crown with low branches that droop down, and is deciduous. The trunk is usually twisted and low branched, with grey-black rough bark. The thick leathery green leaves have a gummy feel to them and are glutinous when young. The plant flowers during the dr ...
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Perr
Perr may refer to: *Yechiel Perr (born 1935), American rabbi *Janet Perr, art director See also

*George Samuel Perrottet (1793–1870), French botanist who used the botanical author abbreviation "Perr." *Per (other) *Purr (other) {{Disambiguation ...
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Combretum Collinum Bild0860
''Combretum'', the bushwillows or combretums, make up the type genus of the family Combretaceae. The genus comprises about 272 species of trees and shrubs, most of which are native to tropical and southern Africa, about 5 to Madagascar, but there are others that are native to tropical Asia, New Guinea and the Bismarck Archipelago, Australia, and tropical America. Though somewhat reminiscent of willows (''Salix'') in their habitus, they are not particularly close relatives of these. Ecology Bushwillow trees often are important plants in their habitat. Savannahs in Africa, in particular those growing on granitic soils, are often dominated by ''Combretum'' and its close relative ''Terminalia''. For example, ''C. apiculatum'' is a notable tree in the Angolan mopane woodlands ecoregion in the Kunene River basin in southern Africa. Other species of this genus are a major component of Southwestern Amazonian moist forests. This genus contains several species that are pollinated ...
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Sahel
The Sahel (; ar, ساحل ' , "coast, shore") is a region in North Africa. It is defined as the ecoclimatic and biogeographic realm of transition between the Sahara to the north and the Sudanian savanna to the south. Having a hot semi-arid climate, it stretches across the south-central latitudes of Northern Africa between the Atlantic Ocean and the Red Sea. The Sahel part of Africa includes – from west to east – parts of northern Senegal, southern Mauritania, central Mali, northern Burkina Faso, the extreme south of Algeria, Niger, the extreme north of Nigeria, Cameroon and Central African Republic, central Chad, central and southern Sudan, the extreme north of South Sudan, Eritrea and Ethiopia. Historically, the western part of the Sahel was sometimes known as the Sudan region (''bilād as-sūdān'' "lands of the Sudan"). This belt was located between the Sahara and the coastal areas of West Africa. There are frequent shortages of food and water due to the dry h ...
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Bògòlanfini
Bògòlanfini or bogolan ( bm, bɔgɔlanfini; "mud cloth"; sometimes called mud-dyed cloth or mud-painted cloth in English) is a handmade Malian cotton fabric traditionally dyed with fermented mud. It has an important place in traditional Malian culture and has, more recently, become a symbol of Malian cultural identity. The cloth is exported worldwide for use in fashion, fine art and decoration. Origins and etymology The dye technique is associated with several Malian ethnic groups, but the Bamana version has become best known outside Mali. In the Bambara language, the word ''bògòlanfini'' is a composite of ''bɔgɔ'', meaning "earth" or "mud"; ''lan'', meaning "with" or "by means of"; and ''fini'', meaning "cloth". Although usually translated as "mud cloth," ''bògòlan'' actually refers to slip clay with a high iron content. The iron in the clay will stain handspun and handwoven cotton textiles black. Production The center of bògòlanfini production, and the source of ...
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Combreglutinin
1-α-''O''-Galloylpunicalagin is an ester of gallic acid and punicalagin, a type of ellagitannin. It is found in the pomegranate ('' Punica granatum'') and in '' Combretum glutinosum''. A study in Taiwan showed that 1-α-''O''-galloylpunicalagin induced nitric oxide production in a dose-dependent manner in endothelial cells via the PI3K/AKT/mTOR pathway The PI3K/AKT/mTOR pathway is an intracellular signaling pathway important in regulating the cell cycle. Therefore, it is directly related to cellular quiescence, proliferation, cancer, and longevity. PI3K activation phosphorylates and activates A .... References Pomegranate ellagitannins Heterocyclic compounds with 7 or more rings Oxygen heterocycles {{aromatic-stub ...
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Punicalagin
Punicalagin is an ellagitannin, a type of phenolic compound. It is found as alpha and beta isomers in pomegranates (''Punica granatum''), ''Terminalia catappa'', ''Terminalia myriocarpa'', and in ''Combretum molle'', the velvet bushwillow, a plant species found in South Africa. These three genera are all Myrtales and the last two are both Combretaceae. Research Punicalagins are water-soluble and hydrolyze into smaller phenolic compounds, such as ellagic acid. There were no toxic effects in rats on a 6% diet of punicalagins for 37 days. In laboratory research, punicalagins had carbonic anhydrase inhibitor Carbonic anhydrase inhibitors are a class of pharmaceuticals that suppress the activity of carbonic anhydrase. Their clinical use has been established as anti-glaucoma agents, diuretics, antiepileptics, in the management of mountain sickness, ... activity. References {{pomegranate ellagitannin Pomegranate ellagitannins Carbonic anhydrase inhibitors ...
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Punicalin
Punicalin is an ellagitannin. It can be found in ''Punica granatum'' (pomegranate) or in the leaves of ''Terminalia catappa'', a plant used to treat dermatitis and hepatitis. It is also reported in ''Combretum glutinosum'', all three species being Myrtales, the two last being Combretaceae. It is a highly active carbonic anhydrase inhibitor. Chemistry The molecule contains a gallagic acid component linked to a glucose Glucose is a simple sugar with the molecular formula . Glucose is overall the most abundant monosaccharide, a subcategory of carbohydrates. Glucose is mainly made by plants and most algae during photosynthesis from water and carbon dioxide, using .... References Pomegranate ellagitannins Carbonic anhydrase inhibitors {{aromatic-stub ...
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Glycoside
In chemistry, a glycoside is a molecule in which a sugar is bound to another functional group via a glycosidic bond. Glycosides play numerous important roles in living organisms. Many plants store chemicals in the form of inactive glycosides. These can be activated by enzyme hydrolysis, which causes the sugar part to be broken off, making the chemical available for use. Many such plant glycosides are used as medications. Several species of ''Heliconius'' butterfly are capable of incorporating these plant compounds as a form of chemical defense against predators. In animals and humans, poisons are often bound to sugar molecules as part of their elimination from the body. In formal terms, a glycoside is any molecule in which a sugar group is bonded through its anomeric carbon to another group via a glycosidic bond. Glycosides can be linked by an O- (an ''O-glycoside''), N- (a ''glycosylamine''), S-(a ''thioglycoside''), or C- (a '' C-glycoside'') glycosidic bond. According to th ...
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Flavonoid
Flavonoids (or bioflavonoids; from the Latin word ''flavus'', meaning yellow, their color in nature) are a class of polyphenolic secondary metabolites found in plants, and thus commonly consumed in the diets of humans. Chemically, flavonoids have the general structure of a 15-carbon skeleton, which consists of two phenyl rings (A and B) and a heterocyclic ring (C, the ring containing the embedded oxygen). This carbon structure can be abbreviated C6-C3-C6. According to the IUPAC nomenclature, they can be classified into: *flavonoids or bioflavonoids *isoflavonoids, derived from 3-phenyl chromen-4-one (3-phenyl-1,4-benzopyrone) structure *neoflavonoids, derived from 4-phenylcoumarine (4-phenyl-1,2-benzopyrone) structure The three flavonoid classes above are all ketone-containing compounds and as such, anthoxanthins ( flavones and flavonols). This class was the first to be termed bioflavonoids. The terms flavonoid and bioflavonoid have also been more loosely used to describe non ...
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Ellagic Acid
Ellagic acid is a polyphenol found in numerous fruits and vegetables. It is the dilactone of hexahydroxydiphenic acid. Name The name comes from the French term ''acide ellagique'', from the word ''galle'' spelled backwards because it can be obtained from ''noix de galle'' ( galls), and to distinguish it from ''acide gallique'' (gallic acid). The molecule structure resembles to that of two gallic acid molecules being assembled "head to tail" and bound together by a C–C bond (as in biphenyl, or in diphenic acid) and two lactone links (cyclic carboxylic esters). Metabolism Biosynthesis Plants produce ellagic acid from hydrolysis of tannins such as ellagitannin and geraniin. Biodegradation Urolithins are gut flora human metabolites of dietary ellagic acid derivatives. Ellagic acid has low bioavailability, with 90% remaining unabsorbed from the intestines until metabolized by microflora to the more bioavailable urolintins. History Ellagic acid was first discovered by ...
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Gallic Acid
Gallic acid (also known as 3,4,5-trihydroxybenzoic acid) is a trihydroxybenzoic acid with the formula C6 H2( OH)3CO2H. It is classified as a phenolic acid. It is found in gallnuts, sumac, witch hazel, tea leaves, oak bark, and other plants. It is a white solid, although samples are typically brown owing to partial oxidation. Salts and esters of gallic acid are termed "gallates". Isolation and derivatives Gallic acid is easily freed from gallotannins by acidic or alkaline hydrolysis. When heated with concentrated sulfuric acid, gallic acid converts to rufigallol. Hydrolyzable tannins break down on hydrolysis to give gallic acid and glucose or ellagic acid and glucose, known as gallotannins and ellagitannins, respectively. Biosynthesis Gallic acid is formed from 3-dehydroshikimate by the action of the enzyme shikimate dehydrogenase to produce 3,5-didehydroshikimate. This latter compound aromatizes. Reactions Oxidation and oxidative coupling Alkaline solutions of gallic a ...
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