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Joseph (Josef) Jadassohn (10 September 1863,
Jadassohn was among the first to take an ''Textbook of contact dermatitis''
by Richard J. G. Rycroft, et al In 1901 he described a rare childhood dermatological disorder known as ''
''Josef Jadassohn''
@
Liegnitz
Legnica (Polish: ; german: Liegnitz, szl, Lignica, cz, Lehnice, la, Lignitium) is a city in southwestern Poland, in the central part of Lower Silesia, on the Kaczawa River (left tributary of the Oder) and the Czarna Woda. Between 1 June 1975 a ...
– 24 March 1936, Zurich) was a German
German(s) may refer to:
* Germany (of or related to)
** Germania (historical use)
* Germans, citizens of Germany, people of German ancestry, or native speakers of the German language
** For citizens of Germany, see also German nationality law
**Ge ...
dermatologist
Dermatology is the branch of medicine dealing with the skin.''Random House Webster's Unabridged Dictionary.'' Random House, Inc. 2001. Page 537. . It is a speciality with both medical and surgical aspects. A dermatologist is a specialist medical ...
.
Biography
He was an assistant to Albert Neisser at the Allerheiligen Hospital in Breslau until 1892, the director of the university skin clinic inBern
german: Berner(in)french: Bernois(e) it, bernese
, neighboring_municipalities = Bremgarten bei Bern, Frauenkappelen, Ittigen, Kirchlindach, Köniz, Mühleberg, Muri bei Bern, Neuenegg, Ostermundigen, Wohlen bei Bern, Zollikofen
, website ...
(1896–1917), and later a professor of dermatology at Breslau University (1917–1932).
Jadassohn was among the first to take an immunological
Immunology is a branch of medicineImmunology for Medical Students, Roderick Nairn, Matthew Helbert, Mosby, 2007 and biology that covers the medical study of immune systems in humans, animals, plants and sapient species. In such we can see there ...
approach in research of dermatological disorders, and contributed to the understanding of the immunopathology Immunopathology is a branch of medicine that deals with immune responses associated with disease. It includes the study of the pathology of an organism, organ system, or disease with respect to the immune system, immunity, and immune responses. In ...
of tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...
and trichophytosis. He was a pioneer in the field of allergology
Allergies, also known as allergic diseases, refer a number of conditions caused by the hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic derma ...
, and is credited for introducing patch testing for diagnosis of contact dermatitis
Contact dermatitis is a type of acute or chronic inflammation of the skin caused by exposure to chemical or physical agents. Symptoms of contact dermatitis can include itchy or dry skin, a red rash, bumps, blisters, or swelling. These rashes are ...
.by Richard J. G. Rycroft, et al In 1901 he described a rare childhood dermatological disorder known as ''
granulosis rubra nasi
Granulosis rubra nasi is a rare familial disease of children, occurring on the nose, cheeks, and chin, characterized by diffuse redness, persistent excessive sweating, and small dark red papules that disappear on diascopic pressure.James, William ...
''.
Conditions
Two dermatological disorders that are named after him are: "Jadassohn's disease I" (a skin disorder originating at theelbow
The elbow is the region between the arm and the forearm that surrounds the elbow joint. The elbow includes prominent landmarks such as the olecranon, the cubital fossa (also called the chelidon, or the elbow pit), and the lateral and the media ...
) and "Jadassohn's disease II" (a natal skin disorder affecting the face and scalp). Together with his assistants, Walter Dössekker (1868–1962), Max Tièche (1878–1938), and Felix Lewandowsky (1879–1921), he shares the following eponymous medical conditions:
* Jadassohn–Dössekker disease: Also known as atypical tuberous myxedema
Myxedema is a term used synonymously with severe hypothyroidism. However, the term is also used to describe a dermatological change that can occur in hyperthyroidism and (rare) paradoxical cases of hypothyroidism. In this latter sense, myxedema ...
.
* Tièche–Jadassohn naevus: A hard, dark blue, benign melanocytic
Melanocytes are melanin-producing neural crest-derived cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea),
the inner ear,
vaginal epithelium, meninges,
bones,
and heart.
...
tumor.
* Jadassohn–Lewandowsky syndrome: An ectodermal dysplasia
Dysplasia is any of various types of abnormal growth or development of cells (microscopic scale) or organs (macroscopic scale), and the abnormal histology or anatomical structure(s) resulting from such growth. Dysplasias on a mainly microscopic ...
characterized by onychogryposis
Onychogryphosis is a hypertrophy that may produce nails resembling claws or a ram's horn.
Causes
Onychogryphosis may be caused by trauma or peripheral vascular disease, but most often secondary to self-neglect and failure to cut the nails for ...
, hyperkeratosis
Hyperkeratosis is thickening of the stratum corneum (the outermost layer of the epidermis, or skin), often associated with the presence of an abnormal quantity of keratin,Kumar, Vinay; Fausto, Nelso; Abbas, Abul (2004) ''Robbins & Cotran Patholo ...
, leukoplakia
Oral leukoplakia is a ''potentially malignant disorder'' affecting the oral mucosa. It is defined as "essentially an oral mucosal white lesion that cannot be considered as any other definable lesion." Oral leukoplakia is a white patch or plaque th ...
, hyperhidrosis
Hyperhidrosis is a condition characterized by abnormally increased sweating, in excess of that required for regulation of body temperature. Although primarily a benign physical burden, hyperhidrosis can deteriorate quality of life from a psychologi ...
and pachyonychia congenita
Pachyonychia congenita (often abbreviated as "PC") is a rare group of autosomal dominant skin disorders that are caused by a mutation in one of five different keratin genes. Pachyonychia congenita is often associated with thickened toenails, plant ...
.
* Nevus Sebaceous of Jadassohn: yellow-orange flat plaque, occurring most commonly on the scalp (60%) or face (30%), usually present at birth, malignant potential (estimated 1%, most commonly basal cell carcinoma), surgically excised prior to hormone-triggered growth during puberty
Literary works
Jadassohn published a revision ofEdmund Lesser
Edmund Lesser (12 May 1852 – 7 June 1918) was a German dermatologist who was a native of Neisse.
He studied medicine at the universities of Berlin, Bonn and Strasbourg, earning his medical doctorate in 1876. Later he became an assistant to Osk ...
’s ''Lehrbuch der Haut- und Geschlechtskrankheiten'' (14th edition, 1927–30), and from 1927 published the multi-volume ''Handbuch für Haut- und Geschlechtskrankheiten''. Other noted written works of his include:
* ''Die venerischen Krankheiten'', (1901).
* ''Ueber eine eigenartige Erkrankung der Nasenhaut bei Kindern'' (Granulosis rubra nasi
Granulosis rubra nasi is a rare familial disease of children, occurring on the nose, cheeks, and chin, characterized by diffuse redness, persistent excessive sweating, and small dark red papules that disappear on diascopic pressure.James, William ...
). Archiv für Dermatologie und Syphilis, Wien, 1901, 58: 145–158.
* ''Die Tuberkulose der Haut''. In: Franz Mracek's Handbuch der Hautkrankheiten (1904).
* ''Allgemeine Ätiologie, Pathologie, Diagnose und Therapie der Gonorrhoe'', (1910).
* ''Lepra'', in Wilhelm Kolle Wilhelm Kolle (born 2 November 1868 in Lerbach near Osterode am Harz, died 10 May 1935) was a German bacteriologist and hygienist. He served as the second director of the Royal Institute for Experimental Therapy, succeeding its founder, the Nobel ...
and August Paul von Wassermann
August Paul von Wassermann (21 February 1866 – 16 March 1925) was a German bacteriologist and hygienist.
Born in Bamberg, with Jewish origins, he studied at several universities throughout Germany, receiving his medical doctorate in 1888 from ...
's Handbuch der pathogenen Microorganismen. second edition, Jena
Jena () is a German city and the second largest city in Thuringia. Together with the nearby cities of Erfurt and Weimar, it forms the central metropolitan area of Thuringia with approximately 500,000 inhabitants, while the city itself has a popu ...
- 1913; third edition, volume 5,2- 1928.
* ''Dermatologie'', (1938).
See also
* Jadassohn–Lewandowsky syndromeReferences and external links
''Josef Jadassohn''
@
Who Named It
''Whonamedit?'' is an online English-language dictionary of medical eponyms and the people associated with their identification. Though it is a dictionary, many eponyms and persons are presented in extensive articles with comprehensive bibliograph ...
{{DEFAULTSORT:Jadassohn, Josef
1863 births
1936 deaths
People from Legnica
German dermatologists
People from the Province of Silesia
Academic staff of the University of Bern
Academic staff of the University of Breslau