Albert Neisser
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Albert Neisser
Albert Ludwig Sigesmund Neisser (22 January 1855, Schweidnitz – 30 July 1916, Breslau) was a German physician who discovered the causative agent (pathogen) of gonorrhea, a strain of bacteria that was named in his honour (''Neisseria gonorrhoeae''). Life and career Neisser was born in the Silesian town of Schweidnitz (now Świdnica, in Poland), the son of a well-known Jewish physician, Moritz Neisser. After he completed the elementary school in Münsterberg, Neisser enrolled in the St. Maria Magdalena School in Breslau (now Wrocław, in Poland). In this school, he was a contemporary of another great name in the history of medicine, Paul Ehrlich. He obtained the Abitur in 1872. Neisser began to study medicine at the University of Breslau, but later moved to Erlangen, completing his studies in 1877. Initially Neisser wanted to be an internist, but did not find a suitable place. He found work, however as an assistant of the dermatologist Oskar Simon (1845–1892), concentra ...
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Świdnica
Świdnica (; german: Schweidnitz; cs, Svídnice; szl, Świdńica) is a city in south-western Poland in the region of Silesia. As of 2019, it has a population of 57,014 inhabitants. It lies in Lower Silesian Voivodeship, being the seventh largest town in that voivodeship. From 1975–98 it was in the former Wałbrzych Voivodeship. It is now the seat of Świdnica County, and also of the smaller district of Gmina Świdnica (although it is not part of the territory of the latter, as the town forms a separate urban gmina). Świdnica became part of the Wałbrzych agglomeration on 23 January 2014. Świdnica is home to the St. Stanislaus and St. Wenceslaus Cathedral and the Church of Peace, two landmark churches listed as Historic Monuments of Poland with the latter also listed as a UNESCO World Heritage Site. History The city's name was first recorded as ''Svidnica'' in 1070, when it was part of Piast-ruled Poland. Świdnica became a town in 1250, although no founding documen ...
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Salvarsan
Arsphenamine, also known as Salvarsan or compound 606, is a drug that was introduced at the beginning of the 1910s as the first effective treatment for syphilis, relapsing fever, and African trypanosomiasis. This organoarsenic compound was the first modern antimicrobial agent. History Arsphenamine was first synthesized in 1907 in Paul Ehrlich's lab by Alfred Bertheim. The antisyphilitic activity of this compound was discovered by Sahachiro Hata in 1909, during a survey of hundreds of newly synthesized organic arsenical compounds. Ehrlich had theorized that by screening many compounds, a drug could be discovered that would have anti-microbial activity but not kill the human patient. Ehrlich's team began their search for such a " magic bullet" among chemical derivatives of the dangerously toxic drug atoxyl. This project was the first organized team effort to optimize the biological activity of a lead compound through systematic chemical modifications, the basis for nearly all mod ...
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Treponema Pallidum
''Treponema pallidum'', formerly known as ''Spirochaeta pallida'', is a spirochaete bacterium with various subspecies that cause the diseases syphilis, bejel (also known as endemic syphilis), and yaws. It is transmitted only among humans. It is a helically coiled microorganism usually 6–15 μm long and 0.1–0.2 μm wide. ''T. pallidum'''s lack of either a tricarboxylic acid cycle or oxidative phosphorylation results in minimal metabolic activity. The treponemes have a cytoplasmic and an outer membrane. Using light microscopy, treponemes are visible only by using dark field illumination. ''Treponema pallidum'' consists of three subspecies, ''T. p. pallidum, T. p. endemicum,'' and ''T. p. pertenue,'' each of which has a distinct associated disease. Subspecies Three subspecies of ''T. pallidum'' are known: * ''Treponema pallidum pallidum'', which causes syphilis * ''T. p. endemicum'', which causes bejel or endemic syphilis * ''T. p. pertenue'', which causes yaws The ...
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August Paul Von Wassermann
August Paul von Wassermann (21 February 1866 – 16 March 1925) was a German bacteriologist and hygienist. Born in Bamberg, with Jewish origins, he studied at several universities throughout Germany, receiving his medical doctorate in 1888 from the University of Strassburg. In 1890 he began work under Robert Koch at the Institute for Infectious Diseases in Berlin. In 1906 he became director of the division for experimental therapy and serum research at the institute, followed by a directorship of the department of experimental therapy at the Kaiser-Wilhelm-Gesellschaft for the Advancement of Science in Berlin-Dahlem (1913).August Paul von Wassermann
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Wassermann developed a
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Apes
Apes (collectively Hominoidea ) are a clade of Old World simians native to sub-Saharan Africa and Southeast Asia (though they were more widespread in Africa, most of Asia, and as well as Europe in prehistory), which together with its sister group Cercopithecidae form the catarrhine clade, cladistically making them monkeys (though this is the subject of much debate). Apes do not have tails due to a mutation of the TBXT gene. In traditional and non-scientific use, the term "ape" can include tailless primates taxonomically considered Cercopithecidae (such as the Barbary ape and black ape), and is thus not equivalent to the scientific taxon Hominoidea. There are two extant branches of the superfamily Hominoidea: the gibbons, or lesser apes; and the hominids, or great apes. * The family Hylobatidae, the lesser apes, include four genera and a total of 20 species of gibbon, including the lar gibbon and the siamang, all native to Asia. They are highly arboreal and bipedal on the g ...
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Syphilis
Syphilis () is a sexually transmitted infection caused by the bacterium ''Treponema pallidum'' subspecies ''pallidum''. The signs and symptoms of syphilis vary depending in which of the four stages it presents (primary, secondary, latent, and tertiary). The primary stage classically presents with a single chancre (a firm, painless, non-itchy skin ulceration usually between 1 cm and 2 cm in diameter) though there may be multiple sores. In secondary syphilis, a diffuse rash occurs, which frequently involves the palms of the hands and soles of the feet. There may also be sores in the mouth or vagina. In latent syphilis, which can last for years, there are few or no symptoms. In tertiary syphilis, there are gummas (soft, non-cancerous growths), neurological problems, or heart symptoms. Syphilis has been known as "the great imitator" as it may cause symptoms similar to many other diseases. Syphilis is most commonly spread through sexual activity. It may also be transmi ...
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Java
Java (; id, Jawa, ; jv, ꦗꦮ; su, ) is one of the Greater Sunda Islands in Indonesia. It is bordered by the Indian Ocean to the south and the Java Sea to the north. With a population of 151.6 million people, Java is the world's List of islands by population, most populous island, home to approximately 56% of the Demographics of Indonesia, Indonesian population. Indonesia's capital city, Jakarta, is on Java's northwestern coast. Many of the best known events in Indonesian history took place on Java. It was the centre of powerful Hindu-Buddhist empires, the Islamic sultanates, and the core of the colonial Dutch East Indies. Java was also the center of the History of Indonesia, Indonesian struggle for independence during the 1930s and 1940s. Java dominates Indonesia politically, economically and culturally. Four of Indonesia's eight UNESCO world heritage sites are located in Java: Ujung Kulon National Park, Borobudur Temple, Prambanan Temple, and Sangiran Early Man Site. ...
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Dermatologist
Dermatology is the branch of medicine dealing with the skin.''Random House Webster's Unabridged Dictionary.'' Random House, Inc. 2001. Page 537. . It is a speciality with both medical and surgical aspects. A dermatologist is a specialist medical doctor who manages diseases related to skin, hair, nails, and some cosmetic problems. Etymology Attested in English in 1819, the word "dermatology" derives from the Greek δέρματος (''dermatos''), genitive of δέρμα (''derma''), "skin" (itself from δέρω ''dero'', "to flay") and -λογία '' -logia''. Neo-Latin ''dermatologia'' was coined in 1630, an anatomical term with various French and German uses attested from the 1730s. History In 1708, the first great school of dermatology became a reality at the famous Hôpital Saint-Louis in Paris, and the first textbooks (Willan's, 1798–1808) and atlases ( Alibert's, 1806–1816) appeared in print around the same time.Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in ...
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Professor Extraordinarius
Academic ranks in Germany are the titles, relative importance and power of professors, researchers, and administrative personnel held in academia. Overview Appointment grades * (Pay grade: ''W3'' or ''W2'') * (''W3'') * (''W2'') * (''W2'', only in ''Baden-Württemberg'') – although paid like a professor appointed at level W2, lecturers in this position do not have a professor title; the term was formerly used in all states for senior lecturer positions with research and teaching responsibilities (''C2'', being phased out since 2002) * (not tenured, only rarely with tenure track) (''W1'') * (not tenured) (''W1'', only in ''Baden-Württemberg'') * or (''A13'', ''A14'', ''A15'') * (''TVöD 13/14/15'', ''TvL 13/14/15'') * (''TVöD'', ''TvL'' ''A13 a. Z.'') * (''TVöD'', only in ''Baden-Württemberg'') * (''TdL'') * (''TdL'') Non-appointment grades * * – conferred, in some German states, to a ''Privatdozent'' who has been in service for several years, without forma ...
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Gerhard Armauer Hansen
Gerhard Henrik Armauer Hansen () (29 July 1841 – 12 February 1912) was a Norwegian physician, remembered for his identification of the bacterium ''Mycobacterium leprae'' in 1873 as the causative agent of leprosy. His distinguished work was recognized at the International Leprosy Congress held at Bergen in 1909. Life Hansen was born in Bergen, Norway, and attended the Bergen Cathedral School. He worked at Rikshospitalet in Christiania (now Oslo) and as a doctor in Lofoten. In 1868 Hansen returned to Bergen to study leprosy while working at Lungegård Hospital (''Lungegårdshospitalet'') with Daniel Cornelius Danielssen, a noted expert. Leprosy was regarded as largely hereditary or otherwise miasmic in origin. Hansen concluded on the basis of epidemiological studies that leprosy was a specific disease with a specific cause. In 1870–71 Hansen travelled to Bonn and Vienna to gain the training necessary for him to prove his hypothesis. In 1873, he announced the discovery ...
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Neisseria Gonorrhoeae
''Neisseria gonorrhoeae'', also known as ''gonococcus'' (singular), or ''gonococci'' (plural), is a species of Gram-negative diplococci bacteria isolated by Albert Ludwig Sigesmund Neisser, Albert Neisser in 1879. It causes the sexually transmitted infection, sexually transmitted genitourinary infection gonorrhea as well as other forms of gonococcal disease including disseminated gonococcemia, septic arthritis, and gonococcal ophthalmia neonatorum. It is oxidase test, oxidase positive and aerobic, and it survives phagocyte, phagocytosis and grows inside neutrophils. Microbiological culture, Culturing it requires carbon dioxide supplementation and enriched agar (chocolate agar) with various antibiotics (Thayer–Martin agar, Thayer–Martin). It exhibits antigenic variation through genetic recombination of its pilus, pili and surface proteins that interact with the immune system. Sexual transmission is through vaginal, anal, or oral sex. Sexual transmission may be prevented throu ...
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