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Gerhard Armauer Hansen
Gerhard Henrik Armauer Hansen (; 29 July 1841 – 12 February 1912) was a Norwegians, Norwegian physician, remembered for his identification of the Bacteria, bacterium ''Mycobacterium leprae'' in 1873 as the causative agent of leprosy. His distinguished work was recognized at the International Leprosy Congress held at Bergen in 1909. Life Hansen was born in Bergen, Norway, and attended the Bergen Cathedral School. He worked at Rikshospitalet in Oslo, Christiania (now Oslo) and as a doctor in Lofoten. In 1868 Hansen returned to Bergen to study leprosy while working at Lungegård Hospital () with Daniel Cornelius Danielssen, a noted expert. Leprosy was regarded as largely hereditary or otherwise miasma theory of disease, miasmic in origin. Hansen concluded on the basis of Epidemiology, epidemiological studies that leprosy was a specific disease with a specific cause. In 1870–71 Hansen travelled to Bonn and Vienna to gain the training necessary for him to prove his hypothesis ...
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Daniel Cornelius Danielssen
Daniel Cornelius Danielssen (4 July 1815 – 13 July 1894) was a Norwegian physician. He was most noted for his research regarding the causes and treatment of leprosy. Biography Danielssen was from Bergen, Norway. Dating from 1839, he was associated with St George's Church, Bergen, St. Jørgens Hospital (''Sankt Jørgens Hospital'') in Bergen. He later worked with Gerhard Armauer Hansen, discovering the bacteria causing leprosy, and made Bergen a world centre of lepra research in the middle of the nineteenth century. With dermatologist Carl Wilhelm Boeck, he was co-author of an acclaimed study on lepra titled ''Om Spedalskhed'' (1847).Daniel Cornelius Danielssen biography
@ Who Named It
In October 1849, he was named head physician of research at Lungegaard Hospital (''Lungegaardshospitalet''). In 1859, German path ...
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Bergen
Bergen (, ) is a city and municipalities of Norway, municipality in Vestland county on the Western Norway, west coast of Norway. Bergen is the list of towns and cities in Norway, second-largest city in Norway after the capital Oslo. By May 2025 the population is 294 029 according to Statistics Norway. The municipality covers and is on the peninsula of Bergenshalvøyen. The city centre and northern neighbourhoods are on Byfjorden (Hordaland), Byfjorden, 'the city fjord'. The city is surrounded by mountains, causing Bergen to be called the "city of Seven Mountains, Bergen, seven mountains". Many of the extra-municipal suburbs are on islands. Bergen is the administrative centre of Vestland county. The city consists of eight boroughs: Arna, Bergen, Arna, Bergenhus, Fana, Bergen, Fana, Fyllingsdalen, Laksevåg, Ytrebygda, Årstad, Bergen, Årstad, and Åsane. Trading in Bergen may have started as early as the 1020s. According to tradition, the city was founded in 1070 by King Ol ...
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Disease
A disease is a particular abnormal condition that adversely affects the structure or function (biology), function of all or part of an organism and is not immediately due to any external injury. Diseases are often known to be medical conditions that are associated with specific signs and symptoms. A disease may be caused by external factors such as pathogens or by internal dysfunctions. For example, internal dysfunctions of the immune system can produce a variety of different diseases, including various forms of immunodeficiency, hypersensitivity, allergy, allergies, and autoimmune disorders. In humans, ''disease'' is often used more broadly to refer to any condition that causes pain, Abnormality (behavior), dysfunction, distress (medicine), distress, social problems, or death to the person affected, or similar problems for those in contact with the person. In this broader sense, it sometimes includes injury in humans, injuries, disability, disabilities, Disorder (medicine) ...
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Cardiovascular Disease
Cardiovascular disease (CVD) is any disease involving the heart or blood vessels. CVDs constitute a class of diseases that includes: coronary artery diseases (e.g. angina, heart attack), heart failure, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, arrhythmia, congenital heart disease, valvular heart disease, carditis, aortic aneurysms, peripheral artery disease, thromboembolic disease, and venous thrombosis. The underlying mechanisms vary depending on the disease. It is estimated that dietary risk factors are associated with 53% of CVD deaths. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by high blood pressure, smoking, diabetes mellitus, lack of exercise, obesity, high blood cholesterol, poor diet, excessive alcohol consumption, and poor sleep, among other things. High blood pressure is estimated to account for approximately 13% of CVD deaths, while tobacco accounts for 9%, di ...
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Syphilis
Syphilis () is a sexually transmitted infection caused by the bacterium ''Treponema pallidum'' subspecies ''pallidum''. The signs and symptoms depend on the stage it presents: primary, secondary, latent syphilis, latent or tertiary. The primary stage classically presents with a single chancre (a firm, painless, non-itchy Ulcer_(dermatology), skin ulceration usually between 1 cm and 2 cm in diameter), though there may be multiple sores. In secondary syphilis, a diffuse rash occurs, which frequently involves the palms of the hands and soles of the feet. There may also be sores in the mouth or vagina. Latent syphilis has no symptoms and can last years. In tertiary syphilis, there are Gumma (pathology), gummas (soft, non-cancerous growths), neurological problems, or heart symptoms. Syphilis has been known as "The Great Imitator, the great imitator", because it may cause symptoms similar to many other diseases. Syphilis is most commonly spread through human sexual activi ...
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Human Subject Research
Human subject research is systematic, scientific investigation that can be either interventional (a "trial") or observational (no "test article") and involves human beings as research subjects, commonly known as test subjects. Human subject research can be either medical (clinical) research or non-medical (e.g., social science) research. Systematic investigation incorporates both the collection and analysis of data in order to answer a specific question. Medical human subject research often involves analysis of biological specimens, epidemiological and behavioral studies and medical chart review studies. (A specific, and especially heavily regulated, type of medical human subject research is the "clinical trial", in which drugs, vaccines and medical devices are evaluated.) On the other hand, human subject research in the social sciences often involves surveys which consist of questions to a particular group of people. Survey methodology includes questionnaires, interviews, ...
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Informed Consent
Informed consent is an applied ethics principle that a person must have sufficient information and understanding before making decisions about accepting risk. Pertinent information may include risks and benefits of treatments, alternative treatments, the patient's role in treatment, and their Right to refuse medical treatment, right to refuse treatment. In most systems, healthcare providers have a legal and ethical responsibility to ensure that a patient's consent is informed. This principle applies more broadly than healthcare intervention, for example to conduct research, to disclose a person's medical information, or to participate in high risk sporting and recreational activities. Within the United States, definitions of informed consent vary, and the standard required is generally determined by the state. As of 2016, nearly half of the states adopted a reasonable patient standard, in which the informed consent process is viewed from the patient's perspective. These standards ...
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Bacillus (shape)
Bacterial cellular morphologies are the shapes that are characteristic of various types of bacteria and often key to their identification. Their direct examination under a light microscope enables the classification of these bacteria (and archaea). Generally, the basic morphologies are spheres (coccus) and round-ended cylinders or rod shaped (bacillus). But, there are also other morphologies such as helically twisted cylinders (example '' Spirochetes''), cylinders curved in one plane (selenomonads) and unusual morphologies (the square, flat box-shaped cells of the Archaean genus '' Haloquadratum)''. Other arrangements include pairs, tetrads, clusters, chains and palisades. Types Coccus A coccus (plural ''cocci'', from the Latin ''coccinus'' (scarlet) and derived from the Greek ''kokkos'' (berry)), is any microorganism (usually bacteria) whose overall shape is spherical or nearly spherical. Coccus refers to the shape of the bacteria and can contain multiple genera, such as st ...
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Microbiological Culture
A microbiological culture, or microbial culture, is a method of multiplying microorganism, microbial organisms by letting them reproduce in predetermined culture medium under controlled laboratory conditions. Microbial cultures are foundational and basic diagnostic methods used as research tools in molecular biology. The term ''culture'' can also refer to the microorganisms being grown. Microbial cultures are used to determine the type of organism, its abundance in the sample being tested, or both. It is one of the primary diagnostic methods of microbiology and used as a tool to determine the cause of infection, infectious disease by letting the agent multiply in a predetermined medium. For example, a throat culture is taken by scraping the lining of tissue in the back of the throat and blotting the sample into a medium to be able to screen for harmful microorganisms, such as ''Streptococcus pyogenes'', the causative agent of strep throat. Furthermore, the term culture is more ge ...
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Etiology
Etiology (; alternatively spelled aetiology or ætiology) is the study of causation or origination. The word is derived from the Greek word ''()'', meaning "giving a reason for" (). More completely, etiology is the study of the causes, origins, or reasons behind the way that things are, or the way they function, or it can refer to the causes themselves. The word is commonly used in medicine (pertaining to causes of disease or illness) and in philosophy, but also in physics, biology, psychology, political science, geography, cosmology, spatial analysis and theology in reference to the causes or origins of various phenomena. In the past, when many physical phenomena were not well understood or when histories were not recorded, myths often arose to provide etiologies. Thus, an etiological myth, or origin myth, is a myth that has arisen, been told over time or written to explain the origins of various social or natural phenomena. For example, Virgil's ''Aeneid'' is a national myth ...
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Staining
Staining is a technique used to enhance contrast in samples, generally at the Microscope, microscopic level. Stains and dyes are frequently used in histology (microscopic study of biological tissue (biology), tissues), in cytology (microscopic study of cell (biology), cells), and in the medical fields of histopathology, hematology, and cytopathology that focus on the study and diagnoses of diseases at the microscopic level. Stains may be used to define biological tissues (highlighting, for example, muscle fibers or connective tissue), cell (biology), cell populations (classifying different blood cells), or organelles within individual cells. In biochemistry, it involves adding a class-specific (DNA, proteins, lipids, carbohydrates) dye to a substrate to qualify or quantify the presence of a specific compound. Staining and fluorescent tagging can serve similar purposes. Biological staining is also used to mark cells in flow cytometry, and to flag proteins or nucleic acids in gel ...
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Albert Neisser
Albert Ludwig Sigesmund Neisser (22 January 1855, Schweidnitz – 30 July 1916, Breslau) was a German physician who discovered the causative agent (pathogen) of gonorrhea, a strain of bacteria that was named in his honour (''Neisseria gonorrhoeae''). Life and career Neisser was born in the Silesian town of Schweidnitz (now Świdnica, in Poland), the son of a well-known Jewish physician, Moritz Neisser. After he completed the elementary school in Münsterberg, Neisser enrolled in the St. Maria Magdalena School in Breslau (now Wrocław, in Poland). In this school, he was a contemporary of another great name in the history of medicine, Paul Ehrlich. He obtained the Abitur in 1872. Neisser began to study medicine at the University of Breslau, but later moved to Erlangen, completing his studies in 1877. Initially Neisser wanted to be an internist, but did not find a suitable place. He found work, however as an assistant of the dermatologist Oskar Simon (1845–1892), concentrat ...
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