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A sprain, also known as a torn ligament, is an acute
soft tissue injury A soft tissue injury is the damage of muscles, ligaments and tendons throughout the body. Common soft tissue injuries usually occur from a sprain, strain, a one-off blow resulting in a contusion or overuse of a particular part of the body. Soft ti ...
of the ligaments within a joint, often caused by a sudden movement abruptly forcing the joint to exceed its functional range of motion. Ligaments are tough, inelastic fibers made of
collagen Collagen () is the main structural protein in the extracellular matrix found in the body's various connective tissues. As the main component of connective tissue, it is the most abundant protein in mammals, making up from 25% to 35% of the whole ...
that connect two or more bones to form a joint and are important for joint stability and proprioception, which is the body's sense of limb position and movement. Sprains can occur at any joint but most commonly occur in the ankle, knee, or wrist. An equivalent injury to a
muscle Skeletal muscles (commonly referred to as muscles) are organs of the vertebrate muscular system and typically are attached by tendons to bones of a skeleton. The muscle cells of skeletal muscles are much longer than in the other types of muscl ...
or tendon is known as a strain. The majority of sprains are mild, causing minor swelling and bruising that can be resolved with
conservative treatment Conservative management is a type of medical treatment defined by the avoidance of invasive measures such as surgery or other invasive procedures, usually with the intent to preserve function or body parts. For example, in appendicitis, conservati ...
, typically summarized as RICE: rest, ice, compression, elevation. However, severe sprains involve complete tears, ruptures, or fractures, often leading to joint instability, severe pain, and decreased functional ability. These sprains require surgical fixation, prolonged immobilization, and
physical therapy Physical therapy (PT), also known as physiotherapy, is one of the allied health professions. It is provided by physical therapists who promote, maintain, or restore health through physical examination, diagnosis, management, prognosis, patient ...
.


Signs and symptoms

*
Pain Pain is a distressing feeling often caused by intense or damaging stimuli. The International Association for the Study of Pain defines pain as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, ...
* Swelling * Bruising or
hematoma A hematoma, also spelled haematoma, or blood suffusion is a localized bleeding outside of blood vessels, due to either disease or trauma including injury or surgery and may involve blood continuing to seep from broken capillary, capillaries. A he ...
caused by broken blood vessels within the injured ligament *Joint instability *Difficulty with bearing weight * Decreased functional ability or range of motion of the injured joint *Ligament rupture may cause a cracking or popping sound at the time of injury Knowing the signs and symptoms of a sprain can be helpful in differentiating the injury from a strain or
fracture Fracture is the separation of an object or material into two or more pieces under the action of stress. The fracture of a solid usually occurs due to the development of certain displacement discontinuity surfaces within the solid. If a displa ...
. Strains typically present with pain, cramping, muscle spasm, and muscle weakness, and fractures typically present with bone tenderness, especially when bearing weight.


Causes

Acute sprains typically occur when the joint is abruptly forced beyond its functional range of motion, often in the setting of trauma or sports injuries. Chronic sprains are caused by repetitive movements leading to overuse.


Mechanism

Ligament A ligament is the fibrous connective tissue that connects bones to other bones. It is also known as ''articular ligament'', ''articular larua'', ''fibrous ligament'', or ''true ligament''. Other ligaments in the body include the: * Peritoneal li ...
s are
collagen Collagen () is the main structural protein in the extracellular matrix found in the body's various connective tissues. As the main component of connective tissue, it is the most abundant protein in mammals, making up from 25% to 35% of the whole ...
fibers that connect bones together, providing passive stabilization to a joint. These fibers can be found in various organizational patterns (parallel, oblique, spiral, etc.) depending on the function of the joint involved. Ligaments can be extra-capsular (located outside the joint capsule), capsular (continuation of the joint capsule), or intra-articular (located within a joint capsule). The location has important implications for healing as blood flow to intra-articular ligaments is diminished compared to extra-capsular or capsular ligaments. Collagen fibers have about a 4% elastic zone where fibers stretch out with increased load on the joint. However, exceeding this elastic limit causes a rupture of fibers, leading to a sprain. It is important to recognize that ligaments adapt to training by increasing the cross-sectional area of fibers. When a ligament is immobilized, the ligament has been shown to rapidly weaken. Normal daily activity is important for maintaining about 80–90% of the mechanical properties of a ligament.


Risk factors

*
Fatigue Fatigue describes a state of tiredness that does not resolve with rest or sleep. In general usage, fatigue is synonymous with extreme tiredness or exhaustion that normally follows prolonged physical or mental activity. When it does not resolve ...
and overuse * High-intensity contact sports * Environmental factors * Poor
conditioning Conditioning may refer to: Science, computing, and technology * Air conditioning, the removal of heat from indoor air for thermal comfort ** Automobile air conditioning, air conditioning in a vehicle ** Ice storage air conditioning, air condition ...
or equipment *Age and
genetic predisposition A genetic predisposition is a genetic characteristic which influences the possible phenotypic development of an individual organism within a species or population under the influence of environmental conditions. In medicine, genetic susceptibilit ...
to ligament injuries * Lack of stretching or " warming up", which when performed properly increases blood flow and joint flexibility


Diagnosis

Sprains can often be diagnosed clinically based on the patient's signs and symptoms, mechanism of injury, and physical examination. However, x-rays can be obtained to help identify fractures, especially in cases of tenderness or bone pain at the injured site. In some instances, particularly if the healing process is prolonged or a more serious injury is suspected,
magnetic resonance imaging Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio wave ...
(MRI) is performed to look at the surrounding soft tissue and
ligament A ligament is the fibrous connective tissue that connects bones to other bones. It is also known as ''articular ligament'', ''articular larua'', ''fibrous ligament'', or ''true ligament''. Other ligaments in the body include the: * Peritoneal li ...
s.


Classification

#First degree sprain (mild) – There is minor stretching and structural damage to the ligament, leading to mild swelling and bruising. Patients typically present without joint instability or decreased range of motion of the joint. #Second degree sprain (moderate) – There is a partial tear of the affected ligament. Patients typically experience moderate swelling, tenderness, and some instability of the joint. There may be some difficulty bearing weight on the affected joint. #Third degree sprain (severe) – There is a complete rupture or tear of the ligament, sometimes avulsing a piece of bone. Patients typically experience severe joint instability, pain, bruising, swelling, and inability to apply weight to the joint.


Joints involved

Although any joint can experience a sprain, some of the more common injuries include the following: * Ankle - Sprains most commonly occur at the ankle and can take longer to heal than ankle bone fractures. Most sprained ankles usually occur in the lateral ligaments on the outside of the ankle. Common causes include walking on uneven surfaces or during contact sports. See sprained ankle or high ankle sprain for more details. **Inversion Ankle Sprain - injury that occurs when ankle rolls inward **Eversion Ankle Sprain - injury that occurs when ankle rolls outward * Toes ** Turf toe (metatarsophalangeal joint sprain) - forced hyperextension of the big toe upwards, especially during sports (initiating a sprint on a hard surface) *
Knee In humans and other primates, the knee joins the thigh with the leg and consists of two joints: one between the femur and tibia (tibiofemoral joint), and one between the femur and patella (patellofemoral joint). It is the largest joint in the hu ...
- Sprains commonly occur at the knee, especially following intense pivoting on a planted leg during contact sports ( American football,
football Football is a family of team sports that involve, to varying degrees, kicking a ball to score a goal. Unqualified, the word ''football'' normally means the form of football that is the most popular where the word is used. Sports commonly c ...
, basketball, pole vaulting, softball, baseball and some styles of
martial arts Martial arts are codified systems and traditions of combat practiced for a number of reasons such as self-defense; military and law enforcement applications; combat sport, competition; physical, mental, and spiritual development; entertainment; a ...
). ** Anterior cruciate ligament (ACL) injury ** Posterior cruciate ligament (PCL) injury **Medial collateral ligament (MCL) injury **Lateral collateral ligament (LCL) injury **Superior Tibiofibular Joint Sprain - typically caused by a twisting injury to the joint connecting the tibia (shinbone) and fibula ** Patellar dislocation * Fingers and wrists - Wrist sprains commonly occur, especially during a fall on an outstretched hand. **
Gamekeeper's thumb Gamekeeper's thumb (also known as skier's thumb or UCL tear) is a type of injury to the ulnar collateral ligament (UCL) of the thumb. The UCL may be merely stretched, or it may be torn from its insertion site into the proximal phalanx of the thum ...
( Skier's thumb) - forceful grabbing that leads to an injury to the ulnar collateral ligament (UCL) at the metacarpophalangeal (MCP) joint of the thumb, historically found in Scottish gamekeepers *
Spine Spine or spinal may refer to: Science Biology * Vertebral column, also known as the backbone * Dendritic spine, a small membranous protrusion from a neuron's dendrite * Thorns, spines, and prickles, needle-like structures in plants * Spine (zoolog ...
**Neck sprain at the
cervical vertebrae In tetrapods, cervical vertebrae (singular: vertebra) are the vertebrae of the neck, immediately below the skull. Truncal vertebrae (divided into thoracic and lumbar vertebrae in mammals) lie caudal (toward the tail) of cervical vertebrae. In ...
** Whiplash (Traumatic Cervical Spine Syndrome) - forced hyperextension and flexion of the neck, classically found in rear-end auto accidents ** Back sprain - Back sprains are one of the most common medical complaints, often caused by poor lifting mechanics and weak core muscles.


Treatment

Treatment of sprains usually involves incorporating conservative measures to reduce the signs and symptoms of sprains, surgery to repair severe tears or ruptures, and rehabilitation to restore function to the injured joint. Although most sprains can be managed without surgery, severe injuries may require tendon
grafting Grafting or graftage is a horticultural technique whereby tissues of plants are joined so as to continue their growth together. The upper part of the combined plant is called the scion () while the lower part is called the rootstock. The succ ...
or ligament repair based on the individual's circumstances. The amount of rehabilitation and time needed for recovery will depend on the severity of the sprain.


Treating Sprains

Depending on the mechanism of injury, joint involvement, and severity, most sprains can be treated using conservative measures following the acronym RICE within the first 24 hours of sustaining an injury. However, it is important to recognize that treatments should be individualized depending on the patient's particular injury and symptoms. Over-the-counter medications such as non-steroidal anti-inflammatory drugs (NSAIDs) can help relieve pain, and topical NSAIDs can be as effective as medications taken by mouth. * Protect: The injured site should be protected and immobilized, as there is an increased risk of recurrent injury to the affected ligaments. * Rest: The joint affected should be immobilized and bearing weight should be minimized. For example, walking should be limited in cases of sprained ankles. * Ice: Ice should be applied immediately to the sprain to reduce swelling and pain. Ice can be applied 3–4 times a day for 10–15 minutes at a time or until the swelling subsides and can be combined with a wrapping for support. Ice can also be used to numb pain but should only be applied for a short period of time (less than twenty minutes) for this purpose. Prolonged ice exposure can reduce blood flow to the injured area and slow the healing process. * Compression: Dressings, bandages, or wraps should be used to immobilize the sprain and provide support. When wrapping the injury, more pressure should be applied to the
distal Standard anatomical terms of location are used to unambiguously describe the anatomy of animals, including humans. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position pro ...
end of the injury and decrease in the direction of the heart. This helps circulate the blood from the extremities to the heart. Careful management of swelling through cold compression therapy is critical to the healing process by preventing further pooling of fluid in the sprained area. However, compression should not impede circulation of the limb. * Elevation: Keeping the sprained joint elevated (in relation to the rest of the body) can minimize swelling. Other non-operative therapies including the continuous passive motion machine (moves joint without patient exertion) and cryocuff (type of cold compress that is activated similarly to a blood pressure cuff) have been effective in reducing swelling and improving range of motion. Recent studies have shown that traction is just as effective as the RICE technique in treating ankle sprains in pediatric patients.


Functional rehabilitation

The components of an effective rehabilitation program for all sprain injuries include increasing the range of motion of the affected joint and progressive muscle strengthening exercises. After implementing conservative measures to reduce swelling and pain, mobilizing the limb within 48–72 hours following injury has been shown to promote healing by stimulating growth factors in musculoskeletal tissues linked to cellular division and matrix remodeling. Prolonged immobilization can delay the healing of a sprain, as it usually leads to
muscle atrophy Muscle atrophy is the loss of skeletal muscle mass. It can be caused by immobility, aging, malnutrition, medications, or a wide range of injuries or diseases that impact the musculoskeletal or nervous system. Muscle atrophy leads to muscle weakness ...
and weakness. Although prolonged immobilization can have a negative effect on recovery, a study in 1996 suggest that the use of bracing can improve healing by alleviating pain and stabilizing the injury to prevent further damage to the ligament or re-injury. When using a brace, it is necessary to ensure adequate blood flow to the extremity. Ultimately, the goal of functional rehabilitation is to return the patient to full daily activities while minimizing the risk of re-injury.


References


External links


Questions and Answers about Sprains and Strains
nbsp;- US National Institute of Arthritis and Musculoskeletal and Skin Diseases {{Authority control Disorders of fascia Dislocations, sprains and strains Hazards of outdoor recreation