Punicalagins
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Punicalagins
The pomegranate ellagitannins, which include punicalagin isomers, are ellagitannins found in the sarcotestas, rind (peel), bark or heartwood of pomegranates (''Punica granatum''). Chemistry As the chemistry of punicalagins became known it was found to be not unique to pomegranate. Punicalagins are present in numerous species of the genus ''Terminalia'', species '' chebula'' Retz. (“Fructus Chebulae”), '' myriocarpa'', '' catappa'' and citrina (tropical flowering trees historically used in African traditional medicine for antibiotic and antifungal purposes). They have also been isolated from '' Cistus salvifolius'' (a Mediterranean shrub) and ''Combretum molle'' (an African shrub). Pomegranate fruits natural phenols can be extracted with ethyl acetate and fractionation can afford the ellagitannin punicalagins. Dietary supplementation A few dietary supplements and nutritional ingredients are available that contain extracts of whole pomegranate and/or are standardized to p ...
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Punicalagin
Punicalagin is an ellagitannin, a type of phenolic compound. It is found as alpha and beta isomers in pomegranates (''Punica granatum''), ''Terminalia catappa'', ''Terminalia myriocarpa'', and in ''Combretum molle'', the velvet bushwillow, a plant species found in South Africa. These three genera are all Myrtales and the last two are both Combretaceae. Research Punicalagins are water-soluble and hydrolyze into smaller phenolic compounds, such as ellagic acid. There were no toxic effects in rats on a 6% diet of punicalagins for 37 days. In laboratory research, punicalagins had carbonic anhydrase inhibitor Carbonic anhydrase inhibitors are a class of pharmaceuticals that suppress the activity of carbonic anhydrase. Their clinical use has been established as anti-glaucoma agents, diuretics, antiepileptics, in the management of mountain sickness, ... activity. References {{pomegranate ellagitannin Pomegranate ellagitannins Carbonic anhydrase inhibitors ...
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Punicalagin
Punicalagin is an ellagitannin, a type of phenolic compound. It is found as alpha and beta isomers in pomegranates (''Punica granatum''), ''Terminalia catappa'', ''Terminalia myriocarpa'', and in ''Combretum molle'', the velvet bushwillow, a plant species found in South Africa. These three genera are all Myrtales and the last two are both Combretaceae. Research Punicalagins are water-soluble and hydrolyze into smaller phenolic compounds, such as ellagic acid. There were no toxic effects in rats on a 6% diet of punicalagins for 37 days. In laboratory research, punicalagins had carbonic anhydrase inhibitor Carbonic anhydrase inhibitors are a class of pharmaceuticals that suppress the activity of carbonic anhydrase. Their clinical use has been established as anti-glaucoma agents, diuretics, antiepileptics, in the management of mountain sickness, ... activity. References {{pomegranate ellagitannin Pomegranate ellagitannins Carbonic anhydrase inhibitors ...
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Pomegranate03 Edit
The pomegranate (''Punica granatum'') is a fruit-bearing deciduous shrub in the family Lythraceae, subfamily Punicoideae, that grows between tall. The pomegranate was originally described throughout the Mediterranean Basin, Mediterranean region. It was introduced into Spanish America in the late 16th century and into California by New Spain, Spanish settlers in 1769. The fruit is typically in season in the Southern Hemisphere from March to May, and in the Northern Hemisphere from September to February. As intact sarcotestas or juice, pomegranates are used in baking, cooking, juice blends, meal garnish (food), garnishes, smoothies, and alcoholic beverages, such as cocktails and wine. Pomegranates are widely cultivated throughout the Middle East and Caucasus region, North Africa, north and tropical Africa, Iran, Armenia, the Indian subcontinent, Central Asia, the drier parts of Southeast Asia, and the Mediterranean Basin. Etymology The name pomegranate derives from medie ...
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Granatin B
Granatin B is an ellagitannin found in the fruit of ''Punica granatum'' (pomegranate). It is a molecule having an enantiomeric dehydrohexahydroxydiphenoyl group. It is a highly active carbonic anhydrase inhibitor Carbonic anhydrase inhibitors are a class of pharmaceuticals that suppress the activity of carbonic anhydrase. Their clinical use has been established as anti-glaucoma agents, diuretics, antiepileptics, in the management of mountain sickness, g .... References Pomegranate ellagitannins Carbonic anhydrase inhibitors {{aromatic-stub ...
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Granatin A
Granatin A is an ellagitannin found in the pericarp of ''Punica granatum'' (pomegranate). It is a weak carbonic anhydrase inhibitor Carbonic anhydrase inhibitors are a class of pharmaceuticals that suppress the activity of carbonic anhydrase. Their clinical use has been established as anti-glaucoma agents, diuretics, antiepileptics, in the management of mountain sickness, g .... References External links Granatin A at the Human Metabolome Database Pomegranate ellagitannins {{aromatic-stub ...
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Punicalin
Punicalin is an ellagitannin. It can be found in ''Punica granatum'' (pomegranate) or in the leaves of ''Terminalia catappa'', a plant used to treat dermatitis and hepatitis. It is also reported in ''Combretum glutinosum'', all three species being Myrtales, the two last being Combretaceae. It is a highly active carbonic anhydrase inhibitor. Chemistry The molecule contains a gallagic acid component linked to a glucose Glucose is a simple sugar with the molecular formula . Glucose is overall the most abundant monosaccharide, a subcategory of carbohydrates. Glucose is mainly made by plants and most algae during photosynthesis from water and carbon dioxide, using .... References Pomegranate ellagitannins Carbonic anhydrase inhibitors {{aromatic-stub ...
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Emblica Officinalis
''Phyllanthus emblica'', also known as emblic, emblic myrobalan, myrobalan, Indian gooseberry, Malacca tree, or amla, from the Sanskrit आमलकी (āmalakī), is a deciduous tree of the family Phyllanthaceae. Its native range is tropical and southern Asia. Plant morphology and harvesting The tree is small to medium in size, reaching in height. The branchlets are not glabrous or finely pubescent, long, usually deciduous; the leaves are simple, subsessile and closely set along branchlets, light green, resembling pinnate leaves. The flowers are greenish-yellow. The fruit is nearly spherical, light greenish-yellow, quite smooth and hard on appearance, with six vertical stripes or furrows. The fruit is up to in diameter, and, while the fruit of wild plants weigh approximately , cultivated fruits average to Ripening in autumn, the berries are harvested by hand after climbing to upper branches bearing the fruits. The taste of Indian emblic is sour, bitter and astringent, ...
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Punigluconin
Punigluconin is an ellagitannin, a polyphenol compound. It is found in the bark of ''Punica granatum'' (pomegranate) and in ''Emblica officinalis''. It is a molecule having a hexahydroxydiphenic acid group and two gallic acids attached to a gluconic acid Gluconic acid is an organic compound with molecular formula C6H12O7 and condensed structural formula HOCH2(CHOH)4COOH. It is one of the 16 stereoisomers of 2,3,4,5,6-pentahydroxyhexanoic acid. In aqueous solution at neutral pH, gluconic acid f ... core. References Pomegranate ellagitannins {{aromatic-stub ...
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Punicafolin
Punicafolin is an ellagitannin from the leaves of ''Punica granatum'' (pomegranate) and in ''Phyllanthus emblica''. Punicafolin is an isomer of tellimagrandin II and nupharin A, but the hexahydroxydiphenoyl Hexahydroxydiphenic acid is an organic compound with the formula HO)3C6HCO2Hsub>2. It is the oxidatively coupled derivative of gallic acid It is a white solid, although samples are typically brown owing to oxidation. left, 142px, Ellagic acid. ... group is not attached to the same hydroxyl groups in the glucose molecule. Punicafolin has been shown to have tumor suppressive effects in dogs.Tanimura S ''et al'' (2005) Suppression of tumor cell invasiveness by hydrolyzable tannins (plant polyphenols) via the inhibition of matrix metalloproteinase-2/-9 activity. ''Biochem Biophys Res Commun'' 330(4):1306-1313 References Pomegranate ellagitannins {{aromatic-stub ...
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Punicacortein D
Punicacortein D is an ellagitannin, a type of phenolic compound. It is found in the bark and heartwoodTwo ellagitannins from Punica granatum heartwood. Sayed A.A El-Toumy and Hans W Rauwald, Phytochemistry, Volume 61, Issue 8, December 2002, Pages 971–974, of ''Punica granatum'' (pomegranate). The molecule contains a gallagic acid component. References External links Knapsack Metabolite information
Pomegranate ellagitannins {{aromatic-stub ...
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