Punicafolin is an ellagitannin from the leaves of ''
Punica granatum
The pomegranate (''Punica granatum'') is a fruit-bearing deciduous shrub in the family Lythraceae, subfamily Punicoideae, that grows between tall.
The pomegranate was originally described throughout the Mediterranean region. It was introduc ...
'' (pomegranate) and in ''
Phyllanthus emblica
''Phyllanthus emblica'', also known as emblic, emblic myrobalan, myrobalan, Indian gooseberry, Malacca tree, or amla, from the Sanskrit आमलकी (āmalakī), is a deciduous tree of the family Phyllanthaceae. Its native range is tropical a ...
''.
Punicafolin is an isomer of
tellimagrandin II
Tellimagrandin II is the first of the ellagitannins formed from 1,2,3,4,6-pentagalloyl-glucose. It can be found in '' Geum japonicum'' and ''Syzygium aromaticum'' (clove).Purification and Characterization of Eugeniin as an Anti-herpesvirus Compoun ...
and
nupharin A, but the
hexahydroxydiphenoyl
Hexahydroxydiphenic acid is an organic compound with the formula HO)3C6HCO2Hsub>2. It is the oxidatively coupled derivative of gallic acid It is a white solid, although samples are typically brown owing to oxidation.
left, 142px, Ellagic acid. ...
group is not attached to the same hydroxyl groups in the glucose molecule.
Punicafolin has been shown to have tumor suppressive effects in dogs.
[Tanimura S ''et al'' (2005) Suppression of tumor cell invasiveness by hydrolyzable tannins (plant polyphenols) via the inhibition of matrix metalloproteinase-2/-9 activity. ''Biochem Biophys Res Commun'' 330(4):1306-1313]
References
Pomegranate ellagitannins
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