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Protothecosis
Protothecosis, otherwise known as Algaemia, is a disease found in dogs, cats, cattle, and humans caused by a type of green alga known as '' Prototheca'' that lacks chlorophyll and enters the human or animal bloodstream. It and its close relative '' Helicosporidium'' are unusual in that they are actually green algae that have become parasites. The two most common species are '' Prototheca wickerhamii'' and '' Prototheca zopfii''. Both are known to cause disease in dogs, while most human cases are caused by ''P. wickerhami''. ''Prototheca'' is found worldwide in sewage and soil. Infection is rare despite high exposure, and can be related to a defective immune system. In dogs, females and Collies are most commonly affected. The first human case was identified in 1964 in Sierra Leone. Cause ''Prototheca'' has been thought to be a mutant of ''Chlorella'', a type of single-celled green alga. However, while ''Chlorella'' contains galactose and galactosamine in the cell wall, ''Pro ...
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Prototheca Wickerhamii
''Prototheca wickerhamii'' is a ubiquitous green alga that does not have chlorophyll. It is widely present in the environment but is a rare cause of opportunistic infection in humans ( protothecosis). Biology ''P. wickerhamii'' has a round to elliptical cell shape measuring 3–11 μm in diameter. The organism has thick wall (''theca'') with internal septations that form the small wedge-shaped endospores, which are arranged radially and moulded (morula-like form). Reproduction is asexual by release of the spores from the sporangia, which can occur every 5–6 hours in ideal conditions.Lass-Flörl C, Mayr A. Human protothecosis. Clin Microbiol Rev. 2007 Apr;20(2):230-42. Review. PMID 17428884 ''P. wickerhamii'' can be found ubiquitously in the environment as '' Prototheca'' species have been found associated with plants, fresh and sea water as well as the soil. ''P. wickerhamii'' can be cultured on Sabouraud dextrose agar. Infection ''P. wickerhamii'' can cause opportun ...
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Algaemia
Algaemia is a secondary term that refers to the emerging condition in which green algae enter the bloodstream. Members of the genus '' Prototheca'' are the most common algae that leads to algaemia. ''Prototheca'' and ''Chlorella'', which is extremely rare, are the only two known algae genera capable of inflicting disease on mammals, including humans, through invasion of host tissue. The majority of cases are observed in dairy cattle as a cause of bovine mastitis as well as other domesticated animals. Cases of algaemia have been observed in dogs and cats as well. Few cases have been observed in humans. Human cases of protothecosis are examined on a case-by-case basis due to the particularity of each case. Protothecosis infection is classified based on the symptoms: (i) cutaneous lesions, (ii) olecranon bursitis, and (iii) disseminated or systemic type infections. Symptoms and signs Protothecosis can affect anyone but is most commonly seen with more severe symptoms in those who h ...
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Prototheca
''Prototheca'' is a genus of algae in the family Chlorellaceae. While this genus is a member of the green algae, all ''Prototheca'' no longer have chloroplasts and therefore their photosynthetic ability. Some species can cause protothecosis in humans and various vertebrates. Etymology From the Greek ''proto''- (first) + ''thēkē'' (sheath), ''Prototheca'' is a genus of variably shaped spherical cells of achloric algae in the family Chlorellaceae. Wilhelm Krüger, a German expert in plant physiology and sugar production, reported ''Prototheca'' microorganisms in 1894, shortly after spending 7 years in Java studying sugarcane. He isolated ''Prototheca'' species from the sap of 3 tree species. Krüger named these organisms as ''P. moriformis'' and ''P. zopfii'', the second name as a tribute to Friedrich Wilhelm Zopf, a renowned botanist, mycologist, and lichenologist. Biology ''Prototheca'' consists of microscopic, single cells, which may sometimes be clustered to form irre ...
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Prototheca Zopfii
''Prototheca zopfii'' is an ubiquitous achlorophyllic (without chlorophyll) green alga. It is a known cause of mastitis in cattle. Taxonomy The genome of this organism's mitochondrion and plastid were first sequenced in 2018.Severgnini M, Lazzari B, Capra E, Chessa S, Luini M, Bordoni R, Castiglioni B, Ricchi M, Cremonesi P (2018) Genome sequencing of Prototheca zopfii genotypes 1 and 2 provides evidence of a severe reduction in organellar genomes. Sci Rep 8(1):14637. doi: 10.1038/s41598-018-32992-0. Polymerase chain reaction and restriction fragment length polymorphism analysis are useful tool for rapid confirmative diagnosis.Molecular characterization of ''Prototheca ''strains isolated from bovine mastitis., A. Aouay , F. Coppée , S. Cloet , P. Cuvelier , A. Belayew , P.-E. Lagneau , C. Mullender ., Journal de Mycologie Médicale (2008) 18, 224—227. Biology ''Prototheca zopfii'' is ubiquitous in nature, but mainly associated with wet areas and places with high amounts of org ...
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Diarrhea
Diarrhea (American English), also spelled diarrhoea or diarrhœa (British English), is the condition of having at least three loose, liquid, or watery bowel movements in a day. It often lasts for a few days and can result in dehydration due to fluid loss. Signs of dehydration often begin with loss of the normal stretchiness of the skin and irritable behaviour. This can progress to decreased urination, loss of skin color, a fast heart rate, and a decrease in responsiveness as it becomes more severe. Loose but non-watery stools in babies who are exclusively breastfed, however, are normal. What is diarrhea? How is it caused, treated and prevented? (see also script)The most common cause is an infection of the intestines due to a virus, bacterium, or parasite—a condition also known as gastroenteritis. These infections are often acquired from food or water that has been contaminated by feces, or directly from another person who is infected. The three types of diarrhea ...
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Brazil
Brazil, officially the Federative Republic of Brazil, is the largest country in South America. It is the world's List of countries and dependencies by area, fifth-largest country by area and the List of countries and dependencies by population, seventh-largest by population, with over 212 million people. The country is a federation composed of 26 Federative units of Brazil, states and a Federal District (Brazil), Federal District, which hosts the capital, Brasília. List of cities in Brazil by population, Its most populous city is São Paulo, followed by Rio de Janeiro. Brazil has the most Portuguese-speaking countries, Portuguese speakers in the world and is the only country in the Americas where Portuguese language, Portuguese is an Portuguese-speaking world, official language. Bounded by the Atlantic Ocean on the east, Brazil has a Coastline of Brazil, coastline of . Covering roughly half of South America's land area, it Borders of Brazil, borders all other countries and ter ...
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United States
The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 contiguous states border Canada to the north and Mexico to the south, with the semi-exclave of Alaska in the northwest and the archipelago of Hawaii in the Pacific Ocean. The United States asserts sovereignty over five Territories of the United States, major island territories and United States Minor Outlying Islands, various uninhabited islands in Oceania and the Caribbean. It is a megadiverse country, with the world's List of countries and dependencies by area, third-largest land area and List of countries and dependencies by population, third-largest population, exceeding 340 million. Its three Metropolitan statistical areas by population, largest metropolitan areas are New York metropolitan area, New York, Greater Los Angeles, Los Angel ...
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Uveitis
Uveitis () is inflammation of the uvea, the pigmented layer of the eye between the inner retina and the outer fibrous layer composed of the sclera and cornea. The uvea consists of the middle layer of pigmented vascular structures of the eye and includes the iris, ciliary body, and choroid. Uveitis is described anatomically, by the part of the eye affected, as anterior, intermediate or posterior, or panuveitic if all parts are involved. Anterior uveitis ( iridocyclitis) is the most common, with the incidence of uveitis overall affecting approximately 1:4500, most commonly those between the ages of 20–60. Symptoms include eye pain, eye redness, floaters and blurred vision, and ophthalmic examination may show dilated ciliary blood vessels and the presence of cells in the anterior chamber. Uveitis may arise spontaneously, have a genetic component, or be associated with an autoimmune disease or infection. While the eye is a relatively protected environment, its immune mecha ...
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Slime Flux
Slime flux, also known as bacterial slime or bacterial wetwood, is a bacterial disease of certain trees, primarily elm, cottonwood, poplar, boxelder, ash, aspen, fruitless mulberry and oak. A wound to the bark, caused by pruning, insects, poor branch angles or natural cracks and splits, causes sap to ooze from the wound. Bacteria may infect this sap causing it to darken and stain the bark, eventually taking on a foamy appearance and unpleasant odor. This slimy ooze becomes toxic to the bark and eats into the tree. The fermented sap attracts insects like flies, ants, and maggots. Cause Slime flux occurs when a wound is made in a tree trunk through things such as natural growth cracks, frost, insects, birds, lawn mowers, cat scratches, or pruning wounds, which causal bacteria can enter. Once inside the xylem, the internal pressure of the tree is raised, from the normal range of up to , due to bacteria fermenting and emitting a gas mixture of methane, nitrogen, carbon dioxide, a ...
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Germany
Germany, officially the Federal Republic of Germany, is a country in Central Europe. It lies between the Baltic Sea and the North Sea to the north and the Alps to the south. Its sixteen States of Germany, constituent states have a total population of over 84 million in an area of , making it the most populous member state of the European Union. It borders Denmark to the north, Poland and the Czech Republic to the east, Austria and Switzerland to the south, and France, Luxembourg, Belgium, and the Netherlands to the west. The Capital of Germany, nation's capital and List of cities in Germany by population, most populous city is Berlin and its main financial centre is Frankfurt; the largest urban area is the Ruhr. Settlement in the territory of modern Germany began in the Lower Paleolithic, with various tribes inhabiting it from the Neolithic onward, chiefly the Celts. Various Germanic peoples, Germanic tribes have inhabited the northern parts of modern Germany since classical ...
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Endemic (epidemiology)
In epidemiology, an infection is said to be endemic in a specific population or populated place when that infection is constantly present, or maintained at a baseline level, without extra infections being brought into the group as a result of travel or similar means. The term describes the distribution of an infectious disease among a group of people or within a populated area. An endemic disease always has a steady, predictable number of people getting sick, but that number can be high ('' hyperendemic'') or low (''hypoendemic''), and the disease can be severe or mild. Also, a disease that is usually endemic can become epidemic. For example, chickenpox is endemic in the United Kingdom, but malaria is not. Every year, there are a few cases of malaria reported in the UK, but these do not lead to sustained transmission in the population due to the lack of a suitable vector (mosquitoes of the genus '' Anopheles''). Consequently, there is no constant baseline level of malaria inf ...
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Mastitis
Mastitis is inflammation of the breast or udder, usually associated with breastfeeding. Symptoms typically include local pain and redness. There is often an associated fever and general soreness. Onset is typically fairly rapid and usually occurs within the first few months of delivery. Complications can include abscess formation. Risk factors include poor latch (breastfeeding), latch, cracked nipples, and weaning. Use of a breast pump has historically been associated with Mastitis, but has been determined as an indirect association. The bacteria most commonly involved are ''Staphylococcus'' and ''Streptococci''. Diagnosis is typically based on symptoms. Ultrasound may be useful for detecting a potential abscess. Prevention of this Breastfeeding difficulties, breastfeeding difficulty is by proper breastfeeding techniques. When infection is present, antibiotics such as cephalexin may be recommended. Breastfeeding should typically be continued, as emptying the breast is import ...
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