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Nucleocytoplasmic Large DNA Viruses
''Nucleocytoviricota'' is a phylum of viruses. Members of the phylum are also known as the nucleocytoplasmic large DNA viruses (NCLDV), which serves as the basis of the name of the phylum with the suffix - for virus phylum. These viruses are referred to as nucleocytoplasmic because they are often able to replicate in both the host's cell nucleus and cytoplasm. The phylum is notable for containing the giant viruses. There are nine families of NCLDVs that all share certain genomic and structural characteristics; however, it is uncertain whether the similarities of the different families of this group have a common viral ancestor. One feature of this group is a large genome and the presence of many genes involved in DNA repair, DNA replication, transcription, and translation. Typically, viruses with smaller genomes do not contain genes for these processes. Most of the viruses in this family also replicate in both the host's nucleus and cytoplasm, thus the name nucleocytoplasmic. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Virus
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898,Dimmock p. 4 more than 9,000 virus species have been described in detail of the millions of types of viruses in the environment. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent particles, or ''virions'', consisting of (i) the genetic material, i. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transcription Factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence. The function of TFs is to regulate—turn on and off—genes in order to make sure that they are expressed in the desired cells at the right time and in the right amount throughout the life of the cell and the organism. Groups of TFs function in a coordinated fashion to direct cell division, cell growth, and cell death throughout life; cell migration and organization (body plan) during embryonic development; and intermittently in response to signals from outside the cell, such as a hormone. There are up to 1600 TFs in the human genome. Transcription factors are members of the proteome as well as regulome. TFs work alone or with other proteins in a complex, by promoting (as an activator), or blocking (as a repressor) the recruitment of RNA ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pokkesviricetes
''Pokkesviricetes'' is a class of viruses. Orders The following orders are recognized: * '' Asfuvirales'' * ''Chitovirales ''Poxviridae'' is a family of double-stranded DNA viruses. Vertebrates and arthropods serve as natural hosts. There are currently 83 species in this family, divided among 22 genera, which are divided into two subfamilies. Diseases associated wit ...'' References Viruses {{Virus-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pandoraviridae
''Pandoraviridae'' is a family of double-stranded DNA viruses that infect amoebae. There is only one genus in this family: ''Pandoravirus''. Several species in this genus have been described, including ''Pandoravirus dulcis'', '' Pandoravirus salinus'' and ''Pandoravirus yedoma''. History The viruses were discovered in 2013. Description The viruses in this family are the second largest known virus (~1 micrometer) in capsid length, after ''Pithovirus'' (1.5 micrometer). ''Pandoravirus'' has the largest viral genome known, containing double-stranded DNA of 1.9 to 2.5 megabase A base pair (bp) is a fundamental unit of double-stranded nucleic acids consisting of two nucleobases bound to each other by hydrogen bonds. They form the building blocks of the DNA double helix and contribute to the folded structure of both D ... pairs. Evolution These viruses appear to be related to the phycodnaviruses. References {{Taxonbar, from=Q16987267 Nucleocytoplasmic large DNA viruses ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phycodnaviridae
''Phycodnaviridae'' is a family of large (100–560 kb) double-stranded DNA viruses that infect marine or freshwater eukaryotic algae. Viruses within this family have a similar morphology, with an icosahedral capsid (polyhedron with 20 faces). As of 2014, there were 33 species in this family, divided among 6 genera. This family belongs to a super-group of large viruses known as nucleocytoplasmic large DNA viruses. Evidence was published in 2014 suggesting that specific strains of ''Phycodnaviridae'' might infect humans rather than just algal species, as was previously believed. Most genera under this family enter the host cell by cell receptor endocytosis and replicate in the nucleus. ''Phycodnaviridae'' play important ecological roles by regulating the growth and productivity of their algal hosts. Algal species such ''Heterosigma akashiwo'' and the genus ''Chrysochromulina'' can form dense blooms which can be damaging to fisheries, resulting in losses in the aquaculture ind ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Algavirales
''Phycodnaviridae'' is a family of large (100–560 kb) double-stranded DNA viruses that infect marine or freshwater eukaryotic algae. Viruses within this family have a similar morphology, with an icosahedral capsid (polyhedron with 20 faces). As of 2014, there were 33 species in this family, divided among 6 genera. This family belongs to a super-group of large viruses known as nucleocytoplasmic large DNA viruses. Evidence was published in 2014 suggesting that specific strains of ''Phycodnaviridae'' might infect humans rather than just algal species, as was previously believed. Most genera under this family enter the host cell by cell receptor endocytosis and replicate in the nucleus. ''Phycodnaviridae'' play important ecological roles by regulating the growth and productivity of their algal hosts. Algal species such ''Heterosigma akashiwo'' and the genus ''Chrysochromulina'' can form dense blooms which can be damaging to fisheries, resulting in losses in the aquaculture in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mimiviridae
''Mimiviridae'' is a family of viruses. Amoeba and other protists serve as natural hosts. The family is divided in up to 4 subfamilies., UCPMS ID: 1889607PDF/ref> Fig. 4 and §Discussion: "Considering that tupanviruses comprise a sister group to amoebal mimiviruses…" Viruses in this family belong to the nucleocytoplasmic large DNA virus clade (NCLDV), also referred to as giant viruses. ''Mimiviridae'' is the sole recognized member of order ''Imitervirales''. ''Phycodnaviridae'' and ''Pandoraviridae'' of ''Algavirales'' are sister groups of ''Mimiviridae'' in many phylogenetic analyses. History The first member of this family, Mimivirus, was discovered in 2003, and the first complete genome sequence was published in 2004. However, the mimivirus Cafeteria roenbergensis virus was isolated and partially characterized in 1995, although the host was misidentified at the time, and the virus was designated BV-PW1. Taxonomy Group: dsDNA Family ''Mimiviridae'' is currently div ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Imitervirales
''Mimiviridae'' is a family of viruses. Amoeba and other protists serve as natural hosts. The family is divided in up to 4 subfamilies., UCPMS ID: 1889607PDF/ref> Fig. 4 and §Discussion: "Considering that tupanviruses comprise a sister group to amoebal mimiviruses…" Viruses in this family belong to the nucleocytoplasmic large DNA virus clade (NCLDV), also referred to as giant viruses. ''Mimiviridae'' is the sole recognized member of order ''Imitervirales''. ''Phycodnaviridae'' and ''Pandoraviridae'' of ''Algavirales'' are sister groups of ''Mimiviridae'' in many phylogenetic analyses. History The first member of this family, Mimivirus, was discovered in 2003, and the first complete genome sequence was published in 2004. However, the mimivirus Cafeteria roenbergensis virus was isolated and partially characterized in 1995, although the host was misidentified at the time, and the virus was designated BV-PW1. Taxonomy Group: dsDNA Family ''Mimiviridae'' is currently div ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pithoviridae
''Pithovirus'', first described in a 2014 paper, is a genus of giant virus known from two species, ''Pithovirus sibericum'', which infects amoebas and ''Pithovirus massiliensis''. It is a base pair, double-stranded DNA virus, and is a member of the nucleocytoplasmic large DNA viruses clade. The 2014 discovery was made when a viable specimen was found in a 30,000-year-old ice core harvested from permafrost in Siberia, Russia. Description The genus name ''Pithovirus'', a reference to large storage containers of ancient Greece known as pithos, pithoi, was chosen to describe the new species. A specimen of ''Pithovirus'' measures approximately 1.5 μm (1500 nanometre, nm) in length and 0.5 μm (500 nm) in diameter, making it the largest virus yet found. It is 50% larger in size than the ''Pandoraviridae'', the previous largest-known viruses, and is larger than ''Ostreococcus'', the smallest eukaryotic cell, although ''Pandoravirus'' has the largest viral genome, contai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marseilleviridae
''Marseilleviridae'' is a family of viruses first named in 2012. The genomes of these viruses are double-stranded DNA. Amoeba are often hosts, but there is evidence that they are found in humans as well. The family contains one genus and four species, two of which are unassigned to a genus. It is a member of the nucleocytoplasmic large DNA viruses ''Nucleocytoviricota'' is a phylum of viruses. Members of the phylum are also known as the nucleocytoplasmic large DNA viruses (NCLDV), which serves as the basis of the name of the phylum with the suffix - for virus phylum. These viruses are refe ... clade. Taxonomy The genus contains the following genera and species: *'' Marseillevirus'' **'' Marseillevirus marseillevirus'' **'' Senegalvirus marseillevirus'' *Species unassigned to a genus: **'' Lausannevirus'' **'' Tunisvirus'' Related Viruses Additional species have since been recognized. The first member of this family recognized has been named ''Acanthamoeba polyphaga marse ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Iridoviridae
''Iridoviridae'' is a family of viruses with double-stranded DNA genomes. Amphibians, fish, and invertebrates such as arthropods serve as natural hosts. There are currently 22 species in this family, divided among two subfamilies and seven genera. Nomenclature The name is derived from Iris, the Greek goddess of the rainbow. This name was chosen because of the "rainbow-like" iridescence observed in heavily infected insects and pelleted samples of invertebrate iridoviruses. It may refer to any member of the ''Iridoviridae'' family or a particular genus within ''Iridoviridae''. Taxonomy The following subfamilies and genera are recognized (-''virinae'' denotes subfamily and -''virus'' denotes genus): * '' Alphairdovirinae'' ** ''Lymphocystivirus'' ** ''Megalocytivirus'' ** ''Ranavirus'' * ''Betairidovirinae'' ** ''Chloriridovirus'' ** '' Daphniairidovirus'' ** '' Decapodiridovirus'' ** ''Iridovirus'' Structure The virions are icosahedral with triangulation number (T) = 189–217, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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